2-Methylcitric acid-d3 is a deuterium-labeled derivative of 2-Methylcitric acid, which functions as a stable isotope useful in metabolic studies. This compound is a key metabolite in the 2-methylcitric acid cycle, accumulating in conditions such as methylmalonic and propionic acidemias, thereby serving as a valuable biomarker. Additionally, 2-Methylcitric acid is known to significantly inhibit ADP-stimulated and uncoupled respiration in mitochondria when supported by glutamate, making it relevant for research on mitochondrial function and metabolic disorders.
2-Methylcitric acid-d3 is a deuterium-labeled derivative of 2-Methylcitric acid, which functions as a stable isotope useful in metabolic studies. This compound is a key metabolite in the 2-methylcitric acid cycle, accumulating in conditions such as methylmalonic and propionic acidemias, thereby serving as a valuable biomarker. Additionally, 2-Methylcitric acid is known to significantly inhibit ADP-stimulated and uncoupled respiration in mitochondria when supported by glutamate, making it relevant for research on mitochondrial function and metabolic disorders.
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