Licofelone

Catalog No.: A11697

COX/LOX inhibitor

Licofelone Chemical Structure

CAS NO. 156897-06-2

Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $760.00

Special Price $608.00

100 mg

Regular Price: $1,200.00

Special Price $960.00

10mM * 1mL in DMSO
$135.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both.
In vitro DMSO 76 mg/mL (200.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL (26.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.32 mL 131.62 mL 263.24 mL
0.5 mM 5.26 mL 26.32 mL 52.65 mL
1 mM 2.63 mL 13.16 mL 26.32 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 379.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11697
Actions Inhibitor
M. Wt 379.88
Formula C23H22ClNO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 156897-06-2
SMILES CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C

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