Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Leucomycin tartrate is a potent 16-membered macrolide antibiotic that primarily targets bacterial protein synthesis. It exhibits strong antibacterial activity against a range of Gram-positive organisms, making it useful in research applications focused on antimicrobial resistance and the mechanisms of action of antibiotics. This compound is instrumental for studies investigating bacterial infections and developing novel therapeutic strategies. -
Antibiotic
Armeniaspirol B is a selective antibiotic that primarily targets Gram-positive pathogens. It exhibits minimal inhibitory concentration (MIC) values of 0.5 μg/mL against Staphylococcus aureus Newman and 2.0 μg/mL against Staphylococcus aureus USA300. This compound is of particular interest for research focused on Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) infections. -
Antibacterial Agent
Valnemulin is a broad-spectrum antibacterial agent with efficacy against both Gram-positive and Gram-negative bacteria, as well as anaerobic bacteria, Mycoplasma, and Spirochetes. It is primarily utilized in veterinary medicine to treat enteric diseases, acute polyarthritis, and enzootic pneumonia in swine. Additionally, Valnemulin demonstrates anti-inflammatory properties, effectively mitigating lipopolysaccharide-induced lung injury in experimental models. -
Antibiotic
TMC-169 is a potent antibiotic belonging to the Aspochalasin group, isolated from Aspergillus flavipes. This compound demonstrates significant anti-tumor activity across various cancer cell types, making it relevant for research into hematologic malignancies, non-small cell lung cancer, breast cancer, and glioma. TMC-169 serves as a valuable tool for exploring therapeutic strategies against these malignancies. -
Bacteriostatic Antibiotic
Trimethoprim sulfate is a potent bacteriostatic antibiotic that functions primarily as a dihydrofolate reductase inhibitor. It exhibits broad-spectrum activity against various Gram-positive and Gram-negative aerobic bacteria, making it valuable in the study of urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim sulfate has demonstrated potential in inhibiting Influenza A virus infection in chick embryos when used in combination with zinc, highlighting its multifaceted applications in microbial research. -
Antibiotic/Antimicrobial Peptide
Aurein 2.2 is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria including Staphylococcus aureus and S. epidermidis. Isolated from the skin secretions of L. aurea, Aurein 2.2 demonstrates potential as an effective antibiotic, making it a valuable tool for research in microbiology and antimicrobial therapy. Its unique mechanism of action and efficacy against resistant strains underline its relevance in the study of infection control and antibiotic development. -
Macrolide Antibiotic
Aldgamycin G is a macrolide antibiotic that targets Gram-positive bacteria. Isolated from Streptomyces avidinii, it exhibits significant antibacterial activity, making it a valuable compound for research in microbiology and antibiotic resistance studies. Its mechanism of action involves inhibition of bacterial protein synthesis, enhancing its utility in the investigation of microbial pathogenicity and treatment options against Gram-positive infections. -
Antibiotic
LL-Z1220 is a novel antibiotic targeting bacterial cell integrity. Featuring a unique 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one structure, it represents the first known natural product containing a benzene dioxide group. LL-Z1220 exhibits valence isomerization, forming 1,4-dioxopentacyclo, with spectral properties indicating a cis configuration of the benzene dioxide moiety. Its distinctive mechanism and structure make it a valuable compound for antibiotic research and development. -
Antibiotic
Daunosamnyl-daunorubicin is an antibiotic that binds to calf thymus DNA, exhibiting significant intercalation properties. This compound is primarily utilized in research focused on anticancer therapies and the study of DNA-drug interactions. Its mechanism of action involves disrupting the normal functioning of DNA, making it valuable for investigations into its therapeutic efficacy against various malignancies. -
Antibacterial Agent
Altromycin D is an antibiotic primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable reagent for research applications focused on the study of bacterial resistance and the development of new antimicrobial therapies. Its specific mechanism of action contributes to its efficacy in inhibiting the growth of pathogenic bacteria. -
Quinolone Antibiotic
Lomefloxacin (aspartate) targets bacterial DNA gyrase, exhibiting potent antibacterial activity as a broad-spectrum quinolone antibiotic. It is effective against a wide range of bacterial pathogens and is utilized in research concerning respiratory tract infections, genitourinary infections, gastrointestinal infections, and ENT infections. Its mechanism of action disrupts bacterial DNA replication, making it a valuable tool for investigating antibiotic resistance and treatment efficacy. -
Antibiotic
Spiramycin (hexanedioate) is a macrolide antibiotic derived from Streptomyces ambofaciens, primarily targeting bacterial infections and Toxoplasma gondii. Its chemical structure features a 16-membered lactone ring with three sugar moieties: mycaminose, forosamine, and mycarose. Spiramycin exhibits significant antibacterial and antiparasitic activity, making it valuable in the study of infectious diseases and potential therapeutic applications. -
Antibiotic
BAL-19403 is a macrolide antibiotic that primarily targets bacterial infections. It demonstrates potent activity against Propionibacterium acnes, specifically against strains resistant to erythromycin and clindamycin. BAL-19403 exhibits both antibacterial and anti-inflammatory properties, making it a valuable reagent for research focused on acne treatment and related inflammatory skin conditions. -
Bacterial Inhibitor
Gramicidin C is a polypeptide antibiotic with a primary mechanism of action as a bacterial inhibitor. It disrupts bacterial cell membrane function, resulting in increased permeability that leads to cell lysis. This compound is widely utilized in microbiology research to study bacterial resistance mechanisms and to investigate antibiotic efficacy against various gram-positive and gram-negative bacteria. -
Antibiotic
BU-2313 A is an antibiotic that exhibits antimicrobial activity through its unique dienoyltetraamide acid structure. This compound is related to streptolysin and tilamycin, making it a valuable tool for studying bacterial resistance mechanisms and evaluating potential therapeutic strategies. Its efficacy in combating bacterial infections positions it as a relevant candidate for research in antimicrobial drug development. -
Peptide Antibiotic
Angiotensin III antipeptide is a peptide antibiotic that inhibits the activity of angiotensin II, a key regulator in the renin-angiotensin system. It exhibits biological activity by modulating blood pressure and fluid balance, making it a valuable tool in cardiovascular and renal research. Its applications include studying the effects of angiotensin peptides on physiological processes and exploring potential therapeutic interventions in related diseases. -
Antitumor Antibiotic
Kapurimycin A2 is an antitumor antibiotic derived from the culture of Streptomyces sp., primarily targeting bacterial infections. It exhibits notable antibacterial activity, particularly against Gram-positive bacteria. This compound is utilized in research applications to investigate its potential therapeutic effects in tumor treatment and microbial resistance studies. -
Antibacterial Agent
Antofloxacin is a potent, orally active broad-spectrum 8-amino-fluoroquinolone that serves as an antibacterial agent. It exhibits enhanced activity against gyrA mutation-positive Helicobacter pylori strains, particularly those with Asn87 mutations, outperforming levofloxacin. Additionally, Antofloxacin acts as a weak, reversible inhibitor of CYP1A2, making it a valuable tool for the study of infections caused by various bacterial species. -
Antibiotic
A2315A, also known as Madumycin II, is an alanine-containing streptogramin A antibiotic that functions as a potent inhibitor of the peptidyl transferase center (PTC) within the ribosome. By targeting the ribosomal machinery, A2315A effectively prevents the initiation of the first cycle of peptide bond formation, demonstrating significant antibiotic activity. This compound is valuable for research focusing on ribosomal function and antibiotic mechanism of action. -
Antibiotic/Antimicrobial Peptide
Aurein 2.6 is an antimicrobial peptide that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, with minimum inhibitory concentrations (MIC) of 25 to 30 μM against various strains, including Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Bacillus subtilis. Aurein 2.6 is valuable for research applications involving antibiotic resistance studies and the development of new antimicrobial agents. -
Antibiotic
Okilactomycin is a lactone antibiotic derived from the culture filtrate of Streptomyces species. It exhibits antibacterial activity by inhibiting bacterial growth mechanisms, making it valuable for studying antibiotic resistance and bacterial infections. This compound can be utilized in research related to microbiology and pharmacology to further understand antibiotic properties and develop new therapeutic strategies. -
Antibiotic
Boromycin is an antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. Isolated from Streptomyces antibioticus, it exhibits potent activity against a range of gram-positive bacteria. This compound is valuable for research applications related to antimicrobial resistance and the development of new therapeutic agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibiotic
Altersolanol B, a fungal-derived compound, exhibits antibiotic properties through its ability to induce ATP catabolism in Ehrlich ascites tumor cells. This molecular action highlights its potential as a research tool for studying cellular energy dynamics and responses to antimicrobial agents. Altersolanol B may contribute to the understanding of antibiotic mechanisms and resistance patterns in cancer biology. -
Antibiotic
Ranbezolid is an orally active oxazolidinone antibiotic primarily targeting Gram-positive and Gram-negative anaerobes, including Staphylococcus aureus and Bacteroides fragilis. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, demonstrating an IC50 of 17 μM. Ranbezolid is effective in rapidly reducing bacterial load and has an enhanced cardiovascular safety profile. This compound is valuable for research applications focused on antibiotic effects against anaerobic bacteria. -
Sulfur-containing Antibiotic
Tropodithietic acid is a sulfur-containing antibiotic derived from the marine bacterium Phaeobacter inhibens. It demonstrates potent antibacterial activity against a wide range of bacterial species, including alpha- and gammaproteobacteria, flavobacteria, and actinobacteria. This compound is valuable for research applications involving antimicrobial resistance and the study of microbial interactions in marine environments. -
Antibiotic, Insecticide
Cafamycin is a polyether antibiotic that targets gram-positive bacteria, notably Staphylococcus aureus. In addition to its antibacterial properties, Cafamycin exhibits insecticidal and antiprotozoal activities. It is isolated from the culture fluid of Streptomyces sp., an organism recognized for producing various bioactive compounds, including the anthracycline antibiotic galtamycin. This compound is valuable for research applications in microbiology and pest control. -
Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways. -
Bacterial Inhibitor
Cefsulodin is a bacterial inhibitor primarily targeting Pseudomonas aeruginosa. It exhibits potent antimicrobial activity against penicillin-susceptible and gentamicin-sensitive strains, demonstrating effectiveness comparable to gentamicin and debendazole. However, Cefsulodin's efficacy is reduced against penicillin-resistant strains of P. aeruginosa, particularly those also resistant to gentamicin. The compound shows a similar minimum inhibitory concentration for P. aeruginosa maltofila when compared to penicillin, gentamicin, and debendazole, while Pseudomonas cepacia strains typically present moderate resistance to Cefsulodin. Its applications include evaluating bacterial resistance mechanisms and antibiotic efficacy in clinical microbiology. -
Antibiotic
Avilamycin A is an orally active antibiotic that targets bacterial pathogens, particularly effective against veterinary strains of Clostridium perfringens (MICs ≤ 0.06-0.5 mg/L) and Brachyspira hyodysenteriae (MICs = 12.5-100 μg/ml). Its potent antibacterial properties make it a valuable reagent for research focused on combating bacterial infections in veterinary medicine. Avilamycin A is often utilized in studies aiming to understand antibiotic resistance mechanisms and to develop new therapeutic strategies against resistant bacterial strains. -
Antibiotic
(R)-10,11-Dehydrocurvularin is an antibiotic derived from the secondary metabolites of Curvularia species. It exhibits concentration-dependent cytotoxicity against various human tumor cell lines, with a mean IC50 value of 1.25 µM. This compound is valuable for research applications in cancer biology and the development of novel antimicrobial agents. -
Antibiotic
Erythromycin C is an antibiotic that primarily targets bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits potent activity against a wide range of gram-positive bacteria and some gram-negative pathogens. Erythromycin C is widely used in research to study bacterial resistance mechanisms and as a model compound in antibiotic development studies. Its properties make it a valuable tool in microbiological and pharmaceutical research. -
Parasite Inhibitor
Asimilobine is an aporphine isoquinoline alkaloid derived from Magnolia obovata. This compound acts as a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist, making it a valuable reagent for studying neurotransmitter pathways. Asimilobine exhibits significant antimalarial and anti-cancer activities, highlighting its potential applications in parasitology and oncology research. -
Diterpene Ester
12-Deoxyphorbol-13-isobutyrate-20-acetate is a diterpene ester that functions as a selective agonist of protein kinase C (PKC). It effectively activates PKC to facilitate the phosphorylation of troponin I and troponin T, contributing to key regulatory pathways in cardiac function. Additionally, this compound has been shown to induce dermal irritation and necrosis in murine models while demonstrating no cocarcinogenic activity. Furthermore, 12-Deoxyphorbol-13-isobutyrate-20-acetate exhibits inhibitory effects on the growth of Aspergillus carbonarius, making it valuable for research in heart failure, cardiomyopathies, and fungal infections. -
Antifugal Agent
Polyoxin D is a potent antifungal agent that acts as a chitin synthetase inhibitor. By disrupting chitin synthesis in fungal cell walls, it effectively inhibits fungal growth and proliferation. This compound is primarily utilized in research settings to study fungal pathogenesis and to explore potential therapeutic strategies against fungal infections. -
Bacterial Inhibitor
Ampicillin is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent in microbiological research and antibiotic susceptibility testing. Ampicillin is commonly used to study bacterial resistance mechanisms and is also employed in molecular biology for the selection of recombinant plasmids in cloning applications. -
SPT Inhibitor
Myriocin is a potent serine palmitoyltransferase (SPT) inhibitor derived from various fungal species such as Myriococcum albomyces, Isaria sinclairi, and Mycelia sterilia. By inhibiting SPT, Myriocin plays a crucial role in the disruption of de novo sphingolipid synthesis. It has demonstrated significant antiviral activity, effectively suppressing the replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL. This compound is valuable for research into sphingolipid metabolism and hepatitis C virus infection mechanisms. -
Antibiotic
Concanamycin A is a macrolide antibiotic that functions as an inhibitor of vacuolar type H+-ATPase (V-ATPase). By inhibiting V-ATPase, Concanamycin A disrupts lysosomal acidification, making it a valuable tool in the study of T cell-mediated inflammation. Its properties allow for exploration of cellular processes related to inflammation and lysosomal function, contributing to a better understanding of various disease mechanisms. -
Antibiotic
Streptomycin is an aminoglycoside antibiotic primarily targeting bacterial protein synthesis by binding to ribosomal RNA. It exhibits potent activity against Mycobacterium tuberculosis, making it essential for tuberculosis research. In addition, Streptomycin demonstrates bactericidal properties against various bacterial infections and interferes with nucleic acid interactions. Furthermore, this compound acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes, enabling its use in studies related to electrophysiological processes. -
CCR3 Antagonist
SB-328437 is a selective non-peptide antagonist of the CCR3 receptor, demonstrating an IC50 of 4.5 nM. This compound effectively inhibits eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4, making it valuable in studies of allergic inflammation. Additionally, SB-328437 has shown the ability to sensitize 5-FU-resistant gastric cancer cells and reduce neutrophil recruitment to the lungs, thus mitigating pulmonary inflammation during acute inflammatory responses. Its applications extend to the investigation of various inflammation-related diseases. -
CCR6 Antagonist
IDOR-1117-2520 is a potent and selective reversible antagonist targeting CCR6. It effectively inhibits CCL20-mediated calcium influx with an IC50 of 63 nM and blocks β-arrestin recruitment to human CCR6, showing an IC50 of 30 nM in recombinant cell models. As a substrate of P-glycoprotein/MDR1, IDOR-1117-2520 is a valuable tool for investigating autoimmune diseases and skin inflammation in research settings. -
Bacterial Metabolite
Palmitoyl serinol is a bacterial metabolite analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). It exhibits enhanced activity in improving the epidermal permeability barrier, demonstrating efficacy in both normal and inflamed skin conditions. Its unique properties make it a valuable tool for research into skin barrier function and inflammation-related studies. -
HIV-I Integrase Inhibitor
Bis-T-23 is a potent inhibitor of HIV-1 integrase, acting through a tyrphostin derivative mechanism. This compound has been shown to promote actin-dependent dynamin oligomerization, highlighting its role in cellular processes related to viral replication. Bis-T-23 is valuable for research focused on HIV and chronic kidney diseases (CKD), providing insights into the intersection of viral infection and renal pathophysiology. -
Myosin I Inhibitor
ZJS178 is a selective inhibitor of myosin I, exhibiting significant antifungal activity against Fusarium graminearum. This compound effectively reduces the synthesis of the mycotoxin deoxynivalenol (DON) and is valuable for research on plant diseases, particularly wheat scab. ZJS178 serves as a potent tool for studies aimed at understanding myosin I functions in fungal pathogenesis and developing strategies for disease management in crops. -
Bacterial Inhibitor
Allergen Gal d 4 (46-61), chicken is a peptide derived from hen egg white lysozyme, exhibiting bacterial inhibitory activity. This compound is utilized in research related to allergenic responses and microbial interactions, making it significant in studies of food allergies and immunological reactions. Its targeted application in bacterial inhibition aids in understanding the role of allergens in various biological systems. -
Antibacterial Agent
Maniladiol is a triterpenoid that serves as an antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 4 mg/mL against the H37Rv strain of M. tuberculosis. This compound is valuable for research focused on tuberculosis infection mechanisms and potential therapeutic applications. -
Antibacterial Agent
8-Desmethyleleutherin is an antibacterial agent derived from the bulbs of Eleutherine americana. It exhibits potent antibacterial activity with minimal inhibitory concentration (MIC) values of 62.5 µg/mL against Staphylococcus aureus strains ATCC27664 and ATCC25923. This compound is valuable for research applications focusing on bacterial resistance and the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 80 is an antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant inhibitory activity against a wide range of gram-positive and gram-negative bacteria. This reagent is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Antibacterial Agent
Xanthoascin is a natural phenolic metabolite that exhibits strong antibacterial activity. Derived from the fermentation products of the endophytic fungus Aspergillus sp. IFB-YXS found in Ginkgo biloba leaves, Xanthoascin demonstrates a minimum inhibitory concentration (MIC) of 0.3125 µg/mL against Clavibacter michiganense subsp. sepedonicus, along with moderate activity against other bacterial pathogens (MIC = 5-20 µg/mL). Its mechanism involves disrupting bacterial cell membrane permeability, resulting in the leakage of nucleic acids. This compound holds potential for research applications in antimicrobial development and the study of plant pathogen interactions.
