Catalog No.
Product Name
Application
Product Information
Citations
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Herbicidal Antibiotic
Phosalacine is a phosphorous-containing tripeptide with herbicidal antibiotic properties, derived from the soil isolate Kitasatosporia phosalacinea KA-338. This compound exhibits significant antibacterial and antifungal activity, making it valuable for research applications in plant protection and microbial control. Its broad-spectrum activity provides an effective tool for studying the mechanisms of action against diverse pathogens. -
Antibiotic
Nikkomycin N is a nucleoside antibiotic derived from Streptomyces tendae, primarily targeting chitin synthesis. This compound demonstrates potent fungicidal and insecticidal activities, making it valuable in studies focused on antifungal and insecticidal mechanisms. Its unique mode of action offers significant research potential in understanding chitin metabolism and developing novel antimicrobial strategies. -
Antibiotic
Pterygospermin is an antibiotic compound derived from the Moringa plant, primarily targeting bacterial and fungal pathogens. This compound exhibits significant antibacterial and fungicidal activity, making it a valuable agent in research focused on antimicrobial properties and drug development. Its efficacy against a range of microorganisms positions Pterygospermin as a potential candidate for further exploration in the fields of microbiology and pharmacology. -
Antibiotic
Alamethicin F 50 is an antibiotic that functions as a membrane-active peptide. It exhibits significant antifungal and antibacterial activity by disrupting microbial cell membrane integrity, leading to cellular content leakage and cell death. Additionally, Alamethicin F 50 reduces water surface tension, making it suitable for applications as a surfactant or detergent in various research settings. -
Antibiotic
Rodaplutin is a ribosomal peptide antibiotic that targets bacterial protein synthesis. It exhibits significant anti-inflammatory effects by inhibiting the release of inflammatory mediators in various animal models. This compound is of particular interest for research applications related to infections and inflammatory diseases, making it a valuable tool for studying potential therapeutic interventions. -
Antibiotic
Ossamycin is a macrolide antibiotic primarily targeting bacterial and fungal infections. It exhibits significant antifungal activity while demonstrating weaker effects against Gram-positive bacteria. In cellular assays, Ossamycin effectively inhibits the proliferation of various cancer cell lines, including L cells, Epstein-Barr ascites cancer cells, KB cells, sarcoma-180 cells, L-1210 cells, and HeLa cells, with IC50 values ranging from 0.003 to 0.008 µg/mL. This makes Ossamycin a valuable tool for research applications in microbiology and oncology. -
Antifungal Antibiotic
Echinocandin B is an antifungal antibiotic that targets the synthesis of β-glucan in the fungal cell wall. It exhibits potent activity against a variety of pathogenic fungi, making it a valuable reagent in antifungal research. This compound is particularly useful for studying fungal infections and evaluating the efficacy of new antifungal therapies. -
Antibiotic
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound primarily acting as an antibiotic. It exhibits a broad range of biological activities including antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antituberculosis, antiparasitic, and antiviral effects. This compound is valuable for research in drug development, infectious disease studies, and the investigation of therapeutic pathways in various biological systems. -
Antibiotic
Tetranactin is an orally active antibiotic targeting Gram-positive bacteria and fungal pathogens. It demonstrates significant insecticidal properties and effectively inhibits the growth of various plant pathogenic fungi in vitro. Toxicity studies indicate a high safety margin, with an LD50 greater than 300 mg/kg for intraperitoneal injection in mice and greater than 15,000 mg/kg overall. This compound is valuable for research applications focusing on antibacterial and antifungal mechanisms. -
Antifungal Antibiotic
3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic that targets fungal infections, derived from Streptomyces subflavus subsp. Irumaensis. This compound exhibits significant antifungal activity against plant pathogenic fungi, including Piricularia oryzae and Sclerotinia cinerea. It is utilized in research focused on antifungal drug development and the study of fungal biology. -
Antibiotic
Adenoregulin, also known as Dermaseptin b2, is an antimicrobial peptide antibiotic that targets a broad spectrum of microorganisms. It exhibits activity against both Gram-negative and Gram-positive bacteria, as well as yeast and fungi. Additionally, Adenoregulin enhances the binding of agonists to the A1 adenosine receptor, making it valuable for research applications in microbiology and pharmacology. -
Antibiotic
TAN 950A is an antifungal amino acid antibiotic that targets excitatory amino acid (EAA) receptors. It exhibits competitive inhibition of [3H]AMPA, [3H]kainate, and [3H]CPP binding, making it a valuable tool for research related to infections and neurological diseases. Its unique mechanism underscores its potential in exploring the relationship between amino acid signaling and various pathophysiological conditions. -
Acylpeptide Antibiotic
Cepafungin III is an acylpeptide antibiotic derived from the culture broth of Pseudomonas species. This compound demonstrates significant inhibitory activity against yeast and fungi, as well as exhibiting antitumor properties against P388 leukemia in murine models, particularly when utilized in conjunction with Cepafungin I and II. Its multifaceted biological activity makes Cepafungin III a valuable reagent for research in antifungal and anticancer studies. -
Antifungal Antibiotic
Amphotericin A is a potent antifungal antibiotic that exerts its activity by binding to ergosterol in fungal cell membranes, leading to increased permeability and cell death. It demonstrates strong efficacy against a variety of fungal pathogens, making it a valuable tool in research focused on fungal infections and therapeutic interventions. Its use spans studies in drug resistance, mechanism of action, and the development of novel antifungal agents. -
Antibiotic
Mildiomycin is an antibiotic derived from Streptoverticillium rimofaciens, primarily targeting powdery mildew in barley. It exhibits inhibitory activity against certain strains of Mycobacterium and Rhodotorula, making it useful for specific antimicrobial applications. However, it is ineffective against the majority of fungi and bacteria, limiting its broad-spectrum utility. -
Antibiotic
Malolactomycin C is a macrolide antifungal antibiotic targeting fungal pathogens. Isolated from Streptomyces strain KP-3144, it demonstrates potent inhibitory activity against Botrytis cinerea, a key agent of gray mold in plants. This compound is valuable for research in plant disease management and the development of antifungal agents. -
Antibiotic
Fenpicoxamid is an antibiotic that targets and inhibits the growth of the fungus Zymoseptoria tritici, demonstrating an effective EC50 value of 0.051 mg/L. This compound is utilized in research applications focused on fungal disease management in crops, providing insights into the mechanisms of fungicide action and resistance. These properties make Fenpicoxamid a valuable tool for studies in plant pathology and agricultural biotechnology. -
Antibiotic
Albaflavenone is a sesquiterpene antibiotic characterized by a zizaene skeleton. It exhibits potent antibacterial activity against Bacillus subtilis, making it valuable for studies in microbial resistance and antibiotic efficacy. Albaflavenone can be utilized in research applications focused on the development of novel antimicrobial agents. -
Antibiotic
Burnettramic acid A is a potent antibiotic derived from Aspergillus burnettii, targeting various bacterial and fungal pathogens. It demonstrates significant antibacterial and antifungal activities, with IC50 values of 0.2 μg/mL against Saccharomyces cerevisiae, 0.5 μg/mL against Candida albicans, 2.3 μg/mL against Bacillus subtilis, and 5.9 μg/mL against Staphylococcus aureus. Additionally, Burnettramic acid A exhibits cytotoxic effects on NS-1 cancer cells, with an IC50 of 13.8 μg/mL, making it a valuable candidate for further research in antimicrobial and anticancer applications. -
Antibiotic/Antimicrobial Peptide
Aurein 2.5 is an antibiotic antimicrobial peptide that exhibits potent antibacterial and antifungal activity. It targets microbial membranes, disrupting their integrity and leading to cell death. This compound is valuable for research applications focused on exploring novel antimicrobial therapies and understanding peptide-microbe interactions. -
Antibiotic
Amphotericin B trihydrate is a polyene antibiotic primarily targeting fungal cell membranes by binding to ergosterol, leading to cell membrane disruption and cell death. This compound exhibits broad-spectrum antifungal activity and is also effective against leishmaniasis, making it valuable in the study of fungal infections and parasitic diseases. Its unique mechanism of action allows for diverse research applications in microbiology and infectious disease studies. -
Antibiotic
Echinosporin is an antibiotic derived from the Amycolatopsis strain, primarily functioning as an antifungal agent. This compound exhibits potent biological activity against various fungal pathogens and demonstrates antitumor properties, making it a valuable reagent for research in microbiology and cancer biology. Its unique mechanism of action provides a useful tool for studies aimed at understanding antifungal resistance and evaluating therapeutic strategies in oncological contexts. -
Antibiotic
Fistupyrone is an antibiotic compound derived from the microbial metabolite of Streptomyces sp. TP-A0569. It exhibits significant activity against Alternaria brassicicola, effectively inhibiting the growth of this pathogen in infected Chinese cabbage. This compound is valuable for research applications focused on plant microbiology and the development of bioactive agents for agricultural protection. -
Antibiotic
Anguinomycin A is an antibiotic with potent inhibitory activity against Ganoderma boninense, exhibiting a minimum inhibitory concentration (MIC) of 5 µg/disk. In addition to its antibacterial properties, Anguinomycin A demonstrates significant antitumor activity. This compound is valuable for research in microbial resistance and cancer therapeutics. -
Antifungal Antibiotic
Aranorosin is a potent antifungal antibiotic that targets fungal cell membrane integrity. Isolated from the culture filtrate and mycelium of the fungus Pseudoarachniotus roseus Kuehn, it exhibits significant antifungal activity against various pathogenic fungi. This compound is valuable for research applications focused on fungal pathogenesis and therapy development. -
Antibiotic
Viridicatumtoxin is a potent antibiotic derived from the fungus Penicillium viridicatum, demonstrating significant antimicrobial activity. With an LD50 of 122.4 mg/kg in rat models, this mycotoxin may have potential applications in the study of bacterial resistance and the development of new antimicrobial therapies. It serves as a valuable tool for researchers investigating the pharmacological properties of novel antibiotics. -
Antitumor Antibiotic
Mazethramycin B is an antitumor antibiotic derived from Streptomyces thioluteus ME561-L4. It exhibits broad-spectrum antimicrobial activity, with minimum inhibitory concentrations of 1.56 μg/mL against Bacillus subtilis and 6.25 μg/mL against Candida pseudotropicalis. Mazethramycin B has shown significant efficacy in enhancing survival rates in L1210 leukemia mouse models, highlighting its potential for further research in cancer treatment and antimicrobial applications. -
Antibiotic
Leucinostatin A is a hydrophobic nonapeptide antibiotic with significant activity against Candida albicans and Cryptococcus neoformans. This compound also demonstrates potential in inhibiting prostate cancer growth by reducing insulin-like growth factor-I expression in prostate stromal cells. Additionally, Leucinostatin A exhibits antiprotozoal properties, making it relevant for various research applications in microbiology and oncology. -
Antibiotic
IT-143A is an antibiotic that demonstrates significant antibacterial and antifungal activity, specifically targeting Micrococcus luteus and Aspergillus fumigatus with a minimum inhibitory concentration (MIC) ranging from 6.25 to 25 μg/mL. Additionally, IT-143A effectively inhibits the proliferation of KB cancer cells with an IC50 of 0.36 ng/mL. This compound is valuable for research applications focusing on microbial resistance and oncology studies. -
Macrolide Antibiotic
PC-766B is a macrolide antibiotic that exhibits significant activity against Gram-positive bacteria, as well as certain fungi and yeasts, while showing no effectiveness against Gram-negative bacteria. Additionally, PC-766B demonstrates antitumor activity against murine tumor cells, making it a candidate for cancer research applications. It also displays weak inhibitory activity against Na+, K+-ATPase, providing insights into its potential biochemical interactions. -
Antibiotic
Leucinostatin D is a peptide antibiotic derived from the fungus Paecilomyces marquandii. It exhibits potent antibacterial activity against Gram-positive bacteria and antifungal effects against select fungal species. This compound is valuable for studying microbial resistance mechanisms and evaluating its potential as a therapeutic agent in treating bacterial and fungal infections. -
Antifungal Antibiotic
UK-2A is a potent antifungal antibiotic that targets fungal organisms through the inhibition of cell wall synthesis. Its ability to disrupt the integrity of the fungal cell wall leads to cell lysis and death, making it an effective agent in combating fungal infections. UK-2A is particularly useful in research applications focused on antifungal drug development and the mechanistic study of fungal resistance. -
Antitumor Antibiotic
Oligomycin E is an antitumor antibiotic derived from Streptomyces. It exhibits potent antifungal activity, with minimum inhibitory concentration (MIC) values ranging from 2 to 75 μg/mL. Oligomycin E demonstrates significant cytotoxicity against HeLa cells, exhibiting an IC50 of 0.014 μg/mL, making it valuable for investigations into cancer therapeutics and antifungal mechanisms. -
Antifungal Antibiotic/Iron Chelator
Dihydroaeruginoic acid functions as an antifungal antibiotic and iron chelator. This thiazoline derivative, synthesized from salicylate and cysteine, effectively chelates Fe(III) and inhibits ribonucleotide reductase, leading to suppressed DNA replication and a G1/S cell cycle block. It demonstrates significant activity against phytopathogenic fungi and bacteria, notably inhibiting the growth of Candida albicans and preventing biofilm formation in Agrobacterium tumefaciens through iron sequestration. Dihydroaeruginoic acid is valuable for research into phytopathogenic infections and leukemia treatment strategies. -
Macrolide Antibiotic
Oligomycin C is a macrolide antibiotic that specifically inhibits ATP synthase, thereby disrupting mitochondrial function. This compound demonstrates potent antifungal activity against a range of pathogens, including Aspergillus niger, Alternaria alternata, Botrytis cinerea, and Phytophthora capsici, making it a valuable tool for studying fungal infections and mitochondrial bioenergetics. Its selective action on fungi, with no antibacterial activity, further emphasizes its utility in antifungal research applications. -
Antibiotic
Asukamycin is a manumycin-type antibiotic derived from Streptomyces nodosus subsp. asukaensis, known for its broad-spectrum antimicrobial properties. This compound exhibits potent antibacterial activity and has been shown to inhibit the growth of various tumor cell lines, making it a valuable reagent for cancer research and antimicrobial studies. -
Antibiotic
Bikaverin is a natural antibiotic compound derived from various fungal species, known for its distinctive reddish pigment. This reagent exhibits effective antimicrobial activity, specifically targeting certain protozoa and fungi. It is commonly used in research applications focused on the exploration of microbial resistance and the development of novel antimicrobial therapies. -
Quinolone Antibiotic
Lomefloxacin hydrochloride is a difluoroquinolone antibiotic that primarily targets bacterial topoisomerase II, inhibiting DNA supercoiling and replication. It exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria and induces reactive oxygen species (ROS) production, leading to apoptosis. Additionally, Lomefloxacin hydrochloride demonstrates anticancer effects, particularly against melanoma, making it a valuable reagent for studying systemic bacterial infections and skin malignancies. -
Antibiotic
Novobiocin sodium is a potent antibiotic that primarily targets DNA gyrase, exhibiting significant inhibitory action in various bacterial strains. Additionally, it acts as an antagonist of heat shock protein 90 (Hsp90), expanding its potential applicability in therapeutic research. Novobiocin sodium is particularly valuable for studies on beta-lactam-resistant pneumococcal infections and demonstrates anti-orthopoxvirus activity, highlighting its relevance in infectious disease research. -
Antibiotic
Bifonazole is an imidazole antifungal agent that primarily targets fungal cell membranes. It exhibits broad-spectrum antibacterial and antifungal activity, making it effective against various dermatophytes and yeast infections. Bifonazole is utilized in research settings to study antifungal mechanisms and evaluate new therapeutic strategies for fungal infections. -
Antibiotic
Phenothiazine is an antibiotic that exhibits broad-spectrum biological activity, including insecticidal, fungicidal, antibacterial, and anthelmintic effects. Additionally, it is instrumental in research related to neurological diseases, offering insights into potential therapeutic mechanisms. This compound serves as a valuable tool for scientists studying microbial resistance and the treatment of parasitic infections. -
Antibiotic
Sulfacetamide sodium is a sulfonamide antibiotic targeting bacterial infections, primarily utilized in ocular research. It exhibits both antibacterial and antifungal activity, making it an important reagent for studying and treating various infections. Applications include investigation of microbial resistance and the efficacy of topical treatments against ocular pathogens. -
Antibiotic
Sulfacetamide sodium monohydrate is a sulfonamide antibiotic primarily targeting bacterial infections. It exhibits both antifungal and antibacterial activities, making it valuable for studying ocular infections. This reagent is useful in research applications that explore mechanisms of infection and treatment efficacy in ophthalmology. -
Antibiotics
Fluconazole hydrate is a triazole antifungal agent that targets fungal cell membrane synthesis by inhibiting the enzyme lanosterol 14-alpha-demethylase. It exhibits significant efficacy against a range of superficial and systemic fungal infections, making it a critical tool in the treatment and prevention of candidiasis and cryptococcosis. Fluconazole hydrate is widely utilized in clinical research to explore antifungal resistance mechanisms and assess therapeutic strategies in various fungal pathogens. -
Antibiotic
(S)-Dihydroaeruginoic acid is an antibiotic derived from Pseudomonas fluorescens, targeting various microbial pathogens. It exhibits substantial antimicrobial activity against a range of fungi, including Rhizoctonia solani, Phytophthora ultimum, Botrytis cinerea, Sclerotium rolfsii, Colletotrichum gloeosporioides, Fusarium oxysporum, and Septoria tritici, as well as against bacterial strains such as Bacillus subtilis, Erwinia herbicola, and Streptomyces albus when assessed at a concentration of 200 μg/disc. This compound is valuable for research focused on antibiotic development and the study of microbial resistance. -
Antibiotic
Verlamelin is a depsipeptide antibiotic that targets and disrupts cellular processes in fungi. It exhibits significant antifungal activity against various plant pathogens, making it a valuable tool for research into plant disease management and fungal biology. Its unique mechanism of action can be explored for insights into antibiotic resistance and the development of new antifungal therapies. -
Antifungal Antibiotic
Mucidin is an antifungal antibiotic that primarily targets the cytochrome bc1 complex within the mitochondrial respiratory chain, inhibiting electron-transfer reactions. This mechanism disrupts ATP production in fungi, leading to their growth inhibition. Mucidin is useful in research applications focused on fungal pathogenesis and mitochondrial function, providing insights into antifungal resistance and treatment strategies. -
Antibiotic
Oudemansin A is an antibiotic that targets fungal pathogens by inhibiting protein, RNA, and DNA synthesis. This compound demonstrates significant antifungal activity, making it a valuable reagent in research focused on the mechanisms of fungal infection and resistance. Its efficacy in disrupting essential cellular processes highlights its potential for exploring new therapeutic approaches in mycology. -
Antibiotic
Pulvilloric acid is an antifungal antibiotic that specifically targets fungal pathogens. Isolated from the fungus Penicillium pulvillorum, this compound exhibits significant antimicrobial activity, making it valuable in research related to antifungal drug development and microbial resistance studies. Its unique mechanism of action positions it as a critical reagent for investigating fungal infections and developing effective therapeutic strategies. -
Antibiotic
Exfoliazone is a phenoxazine antibiotic that targets fungal organisms, specifically demonstrating efficacy against Valsa ceratosperma. This compound exhibits significant antifungal activity, with an effective dose (ED50) for inhibiting mycelial growth calculated at 70 μg/mL. It serves as a valuable tool for studying fungal resistance mechanisms and exploring potential therapeutic applications in mycology research.
