Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Polyhexamethyleneguanidine hydrochloride is a cationic polymer known for its broad-spectrum antimicrobial activity. It primarily exerts its antibacterial effects by interacting with bacterial and fungal cell membranes, leading to disruption of membrane integrity. This compound is valuable in research related to disinfection, water treatment, and agricultural pesticides. -
Antibiotic
Pyrrolnitrin is an antibiotic derived from Pseudomonas pyrrocinia, demonstrating potent activity against a wide range of fungal pathogens, yeast, and gram-positive bacteria. This compound is utilized extensively in research to explore antimicrobial mechanisms and develop therapeutic strategies against resistant infections. Its broad-spectrum effectiveness makes it a valuable tool in microbiological studies and antibiotic susceptibility testing. -
Antibiotic
Piperlonguminine is an alkaloid amide derived from Piper species, exhibiting significant antibacterial properties. Furthermore, it demonstrates a range of biological activities, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, and antifungal effects. This compound is of interest in various research applications, particularly in the fields of pharmaceutical development and disease prevention. -
Antibiotic Agent
Tyrothricin is a polypeptide antibiotic mixture derived from Bacillus brevis, comprising tyrocidines and gramicidins. This compound exhibits broad-spectrum antimicrobial activity, effectively targeting bacteria, fungi, and some viruses. Tyrothricin is commonly used in formulations for the treatment of sore throat and the healing of infected superficial and small-area wounds, making it valuable in both clinical and research settings. -
Antibiotic
α-Terpineol is an antimicrobial compound primarily targeting periodontopathic and cariogenic bacteria. This compound demonstrates significant antifungal activity against Trichophyton mentagrophytes, potentially causing irreversible cellular damage. Additionally, α-Terpineol exhibits antineuropathic and anti-inflammatory properties, making it a valuable reagent for research involving diarrhea, neuropathic pain, infections, and inflammation. -
Antibiotic
Cefaclor monohydrate is an orally active cephalosporin antibiotic that targets penicillin-binding protein 3 (PBP3). It is effective against a variety of bacterial infections, including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections. Additionally, Cefaclor has potential applications in research related to depression and other bacterial pathologies. -
Antibiotic
Erythromycin Ethylsuccinate is an antibiotic that primarily targets bacterial infections by inhibiting protein synthesis in susceptible microorganisms. It demonstrates an antimicrobial spectrum that is comparable to, or slightly broader than, that of penicillin, making it effective against a variety of Gram-positive and some Gram-negative bacteria. Additionally, Erythromycin Ethylsuccinate exhibits antiviral activity against HIV-1, providing a versatile option for researchers studying bacterial and viral pathogens. Its applications include exploring antimicrobial resistance and developing new therapeutic strategies. -
Antibiotic
Oxolinic acid is an antibiotic effective against both Gram-negative and Gram-positive bacteria. It is primarily utilized in research focused on acute and chronic urinary tract infections. Additionally, Oxolinic acid functions as a DNA/RNA synthesis inhibitor and acts as a dopamine uptake inhibitor, demonstrating stimulatory effects on locomotor activity in murine models. -
Antibiotic
Pefloxacin mesylate dihydrate is a broad-spectrum antibiotic that primarily inhibits DNA gyrase, disrupting DNA replication. This compound demonstrates significant antibacterial activity against both Escherichia coli and Pseudomonas aeruginosa, with MIC90 values of 0.12 mg/L and 4 mg/L, respectively, and also targets Bacteroides fragilis with an MIC90 of 16 mg/L. Additionally, Pefloxacin mesylate dihydrate exhibits anti-Plasmodium yoelii activity and can enhance UVA-induced edema and immunosuppression. Its diverse profile makes it a valuable tool for infection studies and related research applications. -
Antibiotic
Succinylsulfathiazole is a sulfonamide antibiotic that targets bacterial folate synthesis, providing localized, gut-specific antibacterial activity. This compound effectively reduces coliform counts, suppresses intestinal bacterial growth, and depletes gut folate-producing bacteria while modulating hepatic mTOR signaling. Succinylsulfathiazole is utilized in research focused on nutrient deficiency and its implications, as it induces folate deficiency and related nutritional symptoms in animal models such as rats and C57BL/6 mice. This antibiotic is valuable for understanding the mechanisms of gut flora modulation and the impact on nutritional status. -
Ansamycin Antibiotic
Rifamycin sodium is an orally active ansamycin antibiotic that inhibits DNA-dependent RNA synthesis. It demonstrates significant antibacterial activity against Mycobacterium tuberculosis and modulates hepatic bile acid metabolism. Additionally, Rifamycin sodium exhibits anti-inflammatory properties, making it valuable for studying Mycobacterium tuberculosis, Bacteroides fragilis infections, and inflammation induced by lipopolysaccharides. -
Antibiotic
Erythromycin thiocyanate is a macrolide antibiotic that targets bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively inhibiting RNA-dependent protein synthesis through interference with transpeptidation and translocation processes. This compound exhibits broad-spectrum antimicrobial activity, making it valuable in research applications related to bacterial infections. Additionally, erythromycin thiocyanate has been shown to possess antitumor and neuroprotective properties, expanding its potential utility across various biomedical research fields. -
Quinolone Antibiotic
Lomefloxacin is a difluoroquinolone antibiotic that primarily targets bacterial topoisomerase II, inhibiting DNA supercoiling and replication. This compound exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria and is effective in inducing reactive oxygen species (ROS) production and apoptosis. Additionally, Lomefloxacin demonstrates promising anticancer efficacy against melanoma, making it a valuable tool for research applications involving systemic bacterial infections and skin cancer studies. -
Antibiotic
Bafilomycin C1 is a macrolide antibiotic that functions as a specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). It exhibits potent antibacterial and antifungal activity, particularly against gram-positive organisms. Additionally, Bafilomycin C1 has been shown to induce apoptosis, making it a valuable tool for research into hepatocellular carcinoma (HCC) and related cellular processes. -
Antibiotic
Metronidazole hydrochloride is a nitroimidazole antibiotic with a primary mechanism of action against anaerobic bacteria. It is effective in the treatment of various anaerobic infections and possesses the ability to penetrate the blood-brain barrier. Research applications include studying its effects on inflammation and skeletal muscle contraction associated with long-term use. -
Polyether Antibiotic
Monensin, a polyether antibiotic, functions primarily as an ionophore that mediates Na+/H+ exchange. It has been identified as a potent inhibitor of Wnt signaling, leading to significant enlargement of multivesicular bodies (MVBs) and modulating exosome secretion. This compound is utilized in research focused on bacterial, fungal, and parasitic infections, and it also exhibits anticancer properties, making it a valuable tool in various biological studies. -
Antibiotic/FOXM1 Inhibitor
Siomycin A is a thiopeptide antibiotic that selectively inhibits Forkhead box M1 (FOXM1), while sparing other Forkhead box family members. It exhibits significant anti-tumor activity and promotes apoptosis, making it a valuable tool for cancer research. This compound is particularly useful for studies focused on the role of FOXM1 in tumorigenesis and therapeutic resistance. -
Antibiotic
Terrein is an antibiotic that functions as a melanogenesis inhibitor. It induces apoptosis in breast cancer cell lines and acts as an inhibitor of quorum sensing and cyclic di-GMP levels in Pseudomonas aeruginosa. This compound is valuable in studying mechanisms of cancer cell regulation and bacterial communication processes. -
Antibiotic/DNA Inhibitor
Bleomycin A5 (hydrochloride) is a glycopeptide antibiotic that primarily functions as a DNA inhibitor. This compound exerts its cytotoxic effects by chelating Fe2+, which leads to the formation of reactive species that induce both single-strand and double-strand breaks in DNA, thereby disrupting DNA replication. Additionally, Bleomycin A5 (hydrochloride) inhibits Drp1-mediated mitochondrial fission and modulates the PINK1/Parkin pathway, contributing to mitochondria-mediated apoptosis. It is widely utilized in cancer research applications. -
Antibiotic and APN Inhibitor
Actinonin is a naturally occurring antibiotic that functions primarily as an aminopeptidase N inhibitor. It exhibits potent antimicrobial activity and acts as a reversible peptide deformylase (PDF) inhibitor with a Ki value of 0.28 nM. Additionally, Actinonin shows inhibitory effects on matrix metalloproteinases MMP-1, MMP-3, MMP-8, and MMP-9, with respective Ki values of 300 nM, 1,700 nM, 190 nM, and 330 nM. It also possesses pro-apoptotic properties and has demonstrated antiproliferative and antitumor activities, making it a valuable tool for cancer research and therapeutic exploration. -
Antibiotic
Bleomycin A5 is a glycopeptide antibiotic that exerts cytotoxic effects primarily through its interaction with Fe2+, leading to the formation of a complex that induces both single-strand and double-strand DNA breaks, while inhibiting DNA replication. Additionally, it targets Drp1-mediated mitochondrial fission and suppresses the PINK1/Parkin pathway-mediated mitophagy, ultimately promoting mitochondria-mediated cellular apoptosis. This compound is valuable in cancer research, particularly in studies focused on mechanisms of apoptosis and DNA damage responses. -
Antibiotic
Tylvalosin is a macrolide antibiotic that exhibits broad-spectrum antimicrobial activity. Primarily utilized as an antiviral agent, Tylvalosin is effective in studying Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection. This compound also induces apoptosis and possesses anti-inflammatory properties, helping to mitigate oxidative stress and acute lung injury by inhibiting NF-κB activation. Its diverse biological activities make Tylvalosin valuable for research in infectious diseases and inflammation. -
Antibiotic
Tylvalosin tartrate is a broad-spectrum macrolide antibiotic primarily targeting bacterial infections. This compound exhibits significant antimicrobial activity and is effective in studying Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infections. Additionally, Tylvalosin tartrate induces apoptosis, demonstrates anti-inflammatory properties, relieves oxidative stress, and mitigates acute lung injury by inhibiting NF-κB activation. It serves as a valuable tool for research into viral pathogenesis and cellular responses. -
Antibiotic
Maduramicin ammonium is a potent antibiotic derived from the actinomycete Actinomadura rubra, primarily functioning as an anticoccidial agent. It effectively targets Eimeria spp., including E. adenoeides, E. gallopavonis, and E. dispersa, making it valuable in the treatment of coccidiosis. Additionally, Maduramicin ammonium has been shown to induce apoptosis in chicken myocardial cells through both intrinsic and extrinsic pathways, underscoring its utility in biological research involving cell viability and apoptosis mechanisms. -
Antitumor Antibiotic
Neocarzinostatin (solution) is a potent antitumor antibiotic that primarily targets double-stranded DNA through the recognition of DNA bulges, leading to the induction of double strand breaks (DSBs). This mechanism initiates apoptosis in cancer cells, making Neocarzinostatin an important reagent for studying DNA damage response and cancer biology. It exhibits potential in the treatment of EpCAM-positive cancers, providing a valuable tool for researchers investigating therapeutic strategies in oncology. -
Antibiotic
Levofloxacin hydrochloride is a fluoroquinolone antibiotic that primarily targets DNA gyrase and topoisomerase IV, leading to the inhibition of bacterial DNA replication and subsequent apoptosis. This compound exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative pathogens, making it suitable for research on infectious diseases, including tuberculosis and chronic periodontitis. Additionally, Levofloxacin hydrochloride demonstrates anticancer effects against lung cancer, along with potential anti-acnegenic, anxiogenic, and analgesic properties. Its effects on sleep duration in murine models further support its utility in various biomedical research applications. -
Antibiotic
Narasin is a cationic ionophore antibiotic that effectively targets various microbial pathogens and acts as a coccidiostat agent. Its biological activity includes the inhibition of NF-κB signaling, leading to the induction of apoptosis in tumor cells. Narasin also exhibits antimicrobial, antiviral, and anticancer properties, specifically inhibiting tumor metastasis and the growth of ERα-positive breast cancer cells by inactivating the TGF-β/SMAD3 and IL-6/STAT3 signaling pathways, making it a valuable tool for cancer research and therapeutic applications. -
Antibiotic
Nonactin is a macrotetrolide antibiotic that functions primarily as a mitochondrial uncoupler. It exhibits antibacterial, insecticidal, and acaricidal properties by acting as an ionophore for monovalent cations such as K+ and NH4+. Additionally, Nonactin inhibits the surface expression of endogenous HSP60 and can induce apoptosis in β-catenin mutant tumor cells, demonstrating its potential for anti-tumor applications. This compound is valuable for research in antibiotic resistance and cancer biology. -
Antibiotic
Quinocetone is an orally active antibiotic that targets various pathogenic microorganisms, making it effective as an animal feed additive to enhance meat production in livestock and poultry. It demonstrates antibacterial activity while also exhibiting tissue-specific toxicity, notably in the liver and lymphocytes. Quinocetone induces autophagy through the ATF6/DAPK1 pathway and activates the NF-κB and iNOS pathways, resulting in cell apoptosis and hepatocyte vacuolar degeneration. Furthermore, it can inhibit the Nrf2/HO-1 pathway and promote the production of reactive oxygen species (ROS), contributing to oxidative stress and DNA damage. -
Antibiotic
Pyoluteorin is an antibiotic with a primary mechanism of inhibiting Oomycete fungi, specifically targeting the plant pathogen Pythium ultimum. This compound effectively suppresses diseases caused by this pathogen in plants. Additionally, Pyoluteorin has been shown to induce apoptosis in human triple-negative breast cancer MDA-MB-231 cells in vitro, making it a valuable reagent for research in human triple-negative breast cancer. -
Antibiotic
2,4-Diacetylphloroglucinol is a polyketide antibiotic that primarily targets a range of pathogenic organisms. This compound demonstrates broad-spectrum antimicrobial activity, effective against bacteria, fungi, oomycetes, and nematodes. Additionally, 2,4-Diacetylphloroglucinol is known to inhibit plant pathogens and can influence root development in tomato seedlings, making it valuable for agricultural research and pathogen control studies. -
Antibiotic
Ascochlorin is an isoprenoid antibiotic that primarily targets the STAT3 signaling cascade, leading to the suppression of tumor growth. It has demonstrated the ability to induce apoptosis in cancer cells while exhibiting anti-inflammatory properties. This compound is valuable for research applications focusing on cancer biology, inflammation, and the modulation of intracellular signaling pathways. -
Antitumor Antibiotic
Peplomycin is an analog of bleomycin that functions as an antitumor antibiotic. It demonstrates significant antitumor activity while exhibiting lower pulmonary toxicity compared to its parent compound. Peplomycin is known to induce apoptosis in oral squamous cell carcinoma (SSCKN) cells and may lead to skin abnormalities and pulmonary fibrosis. This compound is valuable for research related to tumors, pulmonary fibrosis, and associated diseases. -
Antibiotic Agent
Nargenicin A1 is an antibiotic agent primarily targeting Gram-positive bacteria. It exhibits anti-inflammatory properties and has been shown to protect HINAE cells from DNA damage and apoptosis induced by Tacrolimus. Additionally, Nargenicin A1 is relevant for research applications related to acute myeloid leukemia, making it a valuable compound for studies in both infection and cancer biology. -
Antibiotic
Undecylprodigiosin is an antibiotic derived from the prodiginine family, known for its potent antibacterial properties. It has been shown to selectively induce apoptosis in human breast carcinoma cells independently of the p53 pathway, demonstrating its potential as an anticancer agent. Additionally, undecylprodigiosin possesses immunosuppressive and antimicrobial activities, making it a valuable tool in cancer research and antimicrobial studies. -
Antibiotic
Arisostatin A is a microbial secondary metabolite with antibiotic activity specifically against Gram-positive bacteria. It exhibits potent anti-tumor effects by inducing apoptosis through the activation of caspase-3 and the generation of reactive oxygen species (ROS) in AMC-HN-4 cells. This compound is valuable for research applications in cancer biology and antimicrobial studies. -
Antifungal Antibiotic
Filipin complex is a potent polyene macrolide antifungal antibiotic that primarily targets membrane cholesterol. By inserting into cellular membranes, it sequesters cholesterol, thereby inhibiting the entry of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The complex comprises approximately 75.8% Filipin III, 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I, making it a valuable tool in antifungal research and viral entry studies. Its characteristic fluorescence spectrum (Ex/Em = 380/430 nm) further enhances its utility in biological applications. -
Antibiotic
Nourseothricin sulfate is a broad-spectrum antibiotic that targets the outer membrane of Gram-negative bacteria, effectively disrupting their integrity. This compound inhibits protein biosynthesis in prokaryotic cells and demonstrates significant antifungal activity against eukaryotic organisms. It is widely utilized as a selective marker in various applications, including the transformation of bacteria, yeast, filamentous fungi, and plant cells, facilitating research in microbiology and molecular biology. -
Antibiotic
Aurachin D is an antibiotic that primarily targets Gram-positive bacteria and certain fungi. It functions by inhibiting NADH oxidation in beef heart submitochondrial particles, which disrupts cellular respiration and energy production. This compound is valuable for research applications focused on understanding bacterial and fungal resistance mechanisms as well as exploring metabolic pathways. -
Antifungal Antibiotic/Complex III Inhibitor
Myxothiazol is an antifungal antibiotic that acts as an inhibitor of mitochondrial electron transport chain complex III (bc1 complex). It demonstrates potent antifungal activity against various yeasts and fungi, exhibiting effective growth inhibition at concentrations ranging from 0.01 to 3 μg/ml. This compound is valuable for research applications focused on mitochondrial function and the mechanisms of antifungal resistance. -
Antibiotic Fungicide
Validamycin A acts as an antibiotic fungicide primarily targeting fungal pathogens. Isolated from Streptomyces hygroscopicus var. limoneus, it exhibits significant inhibitory effects against Aspergillus flavus, with a minimum inhibitory concentration (MIC) of 1 µg/mL. Additionally, Validamycin A demonstrates potent inhibition of trehalase in Rhizoctonia solani, with an IC50 value of 72 µM. It also functions as a reversible inhibitor of tyrosinase, exhibiting a Ki value of 5.893 mM, making it a valuable reagent for agricultural and biochemical research applications. -
Antitumor Antibiotic
Peplomycin sulfate is an antitumor antibiotic that acts by inducing DNA strand breaks, thereby promoting apoptosis in cancer cells. It exhibits significant antitumor activity while displaying relatively low pulmonary toxicity. Additionally, Peplomycin sulfate has been shown to induce various skin abnormalities and can lead to pulmonary fibrosis. This compound is valuable for research applications related to cancer, pulmonary fibrosis, and other associated diseases. -
Anti-tumour Antibiotic
Boanmycin is an anti-tumor antibiotic that exerts its biological activity by inducing cellular senescence and apoptosis in cancer cells. This compound is primarily utilized in research to explore mechanisms of tumor suppression and to assess its potential therapeutic applications in oncology. Its ability to promote programmed cell death makes it a valuable tool for studying cancer biology and developing novel treatment strategies. -
Antibiotic
4-Epianhydrotetracycline hydrochloride is an antibiotic that serves as a significant intermediate in tetracycline synthesis. It demonstrates cytotoxic effects and induces apoptosis in zebrafish embryos, highlighting its potential for developmental toxicology studies. Furthermore, it exhibits antimicrobial activity against Shewanella, Escherichia coli, and Pseudomonas aeruginosa, with minimum inhibitory concentrations of 2 mg/L, 1 mg/L, and 64 mg/L, respectively, indicating its utility in microbial resistance research. -
Antibiotic
Deoxynybomycin is an antibiotic that acts as an inhibitor of DNA gyrase and Topoisomerase I. It demonstrates significant antibacterial activity against Staphylococcus aureus and induces the expression of p21/WAF1. Additionally, Deoxynybomycin exhibits cytotoxic effects and promotes apoptosis in various cancer cell lines, including Saos-2, TMK-1, and THP-1, making it a valuable tool for research in antimicrobial and cancer biology. -
Anti-tumour Antibiotic
Boanmycin hydrochloride is an anti-tumor antibiotic that exhibits significant cytotoxic effects against various cancer cell lines. It functions by inducing cellular senescence and apoptosis, making it a valuable tool for studying mechanisms of tumor progression and resistance. This compound is useful in cancer research and can aid in the development of therapeutic strategies targeting malignant cells. -
Antibiotic
Undecylprodigiosin hydrochloride is an antibiotic derived from the prodiginine class of compounds. It exhibits potent antimicrobial activity and selectively induces apoptosis in human breast carcinoma cells through a p53-independent mechanism. Additionally, this compound demonstrates immunosuppressive and anticancer properties, making it a valuable tool for research in cancer therapy and microbial studies. -
Antitumor Antibiotic
Antibiotic DC 81 is a potent antitumor antibiotic derived from Streptomyces species, classified as a pyrrolo[2,1-c][1,4]benzodiazepine (PBD). It functions primarily as an inhibitor of nucleic acid synthesis by recognizing and binding to specific DNA sequences, resulting in the formation of a labile covalent adduct. This ability to interact with DNA makes Antibiotic DC 81 valuable for research in cancer biology and the development of novel therapeutic agents targeting DNA. -
Antibiotic
FSL-1 is a bacterial-derived agonist of toll-like receptor 2/6 (TLR2/6). It exhibits immunostimulatory activity that enhances resistance against experimental Herpes Simplex Virus Type 2 (HSV-2) infection. This compound is valuable for research applications focused on innate immunity and the development of therapeutic strategies for viral infections. -
Antitumor Antibiotic
Herbimycin B is an ansamycin antibiotic targeting Src family tyrosine kinases. It exhibits significant antitumor activity by inhibiting cell proliferation in various cancer cell lines, including HeLa and Ehrlich cells. Additionally, Herbimycin B demonstrates a herbicidal effect on both monocotyledons and dicotyledons and can inhibit the tobacco mosaic virus (TMV), making it relevant for studies in plant pathology and cancer research.
