Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Pisiferic acid is an antibacterial agent that exhibits inhibitory activity against both Gram-negative and Gram-positive bacteria, including Proteus vulgaris, Staphylococcus aureus, and Bacillus subtilis. It serves as a valuable tool for research on bacterial infections, allowing for the exploration of mechanisms of antibacterial resistance and the development of new therapeutic strategies. -
Antibacterial Agent
Dup-721 is an orally active broad-spectrum antibacterial agent that exhibits significant efficacy against a range of both clinically susceptible and resistant bacterial strains, with particular activity against Mycobacterium tuberculosis. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing novel therapeutic strategies for tuberculosis and other bacterial infections. -
Bacterial Inhibitor
Aureothricin is a dithiolopyrrolone (DTP) antibiotic with a primary mechanism of inhibiting bacterial growth. It demonstrates broad-spectrum antibiotic activity and has the ability to impede the adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin. This compound is valuable for research applications focused on bacterial inhibition and the modulation of cell adhesion processes. -
Bacterial Inhibitor
Flomoxef is an oxacephem antibiotic that exerts its bactericidal effects primarily by inhibiting bacterial cell wall synthesis. It demonstrates significant activity against a range of Gram-positive bacteria. This compound is utilized in research settings to investigate antibiotic resistance mechanisms and to develop novel antibacterial agents. -
Bacterial Inhibitor
Flucloxacillin is a β-lactam antibiotic that primarily targets bacterial cell wall synthesis by inhibiting transpeptidation enzymes. It exhibits potent antibacterial activity against a variety of gram-positive and some gram-negative bacteria, making it valuable in treating infections caused by staphylococci and streptococci. This reagent is widely utilized in microbiological studies and antibiotic susceptibility testing to evaluate bacterial resistance. -
Antibacterial Peptide
D2A21 is an antibacterial peptide derived from cecropins that exhibits potent antimicrobial activity. It has a minimum cidal concentration of 21.69 μg/mL against Chlamydia trachomatis, demonstrating its effectiveness in combating bacterial infections. This peptide is valuable for research applications aimed at developing novel antimicrobial therapies and studying bacterial resistance mechanisms. -
Bacterial Inhibitor
Sulfadimethoxine-d6 is a deuterated form of Sulfadimethoxine, a sulfonamide antibiotic that acts as a bacterial inhibitor by interfering with folate synthesis in pathogenic microorganisms. This reagent is primarily utilized in pharmacokinetics and metabolic studies, allowing for improved tracking of the compound in biological systems. Its deuterium labeling enhances analytical sensitivity in various applications, including drug metabolism research and isolation studies. -
Antibacterial Agent
Avilamycin C is an avilamycin-type antibiotic that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity, particularly against Gram-positive bacteria, making it valuable in research focused on antibiotic resistance and bacterial infections. This compound serves as a crucial tool for studies investigating mechanisms of action and the development of novel antibacterial therapies. -
Bacterial Inhibitor
Bacampicillin is a penicillin antibiotic that serves as a prodrug of ampicillin, designed to enhance oral bioavailability. It exerts its antibacterial activity through the inhibition of cell wall synthesis in susceptible bacteria. This compound is utilized primarily in microbiological research and studies targeting bacterial infections. -
Antibacterial Agent
Ticarcillin is a semisynthetic carboxypenicillin with extended-spectrum antibacterial activity, primarily targeting bacterial cell wall synthesis. It is effective against a range of gram-positive cocci, such as streptococci and staphylococci, as well as most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin is relevant for research applications involving lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intra-abdominal infections. -
Antibacterial Agent
Cloxacillin is an orally active antibacterial agent and β-lactamase inhibitor, exhibiting an IC50 of 0.04 µM. It effectively suppresses the inflammatory response induced by Staphylococcus aureus by inhibiting the activation of mitogen-activated protein kinases (MAPKs), nuclear factor kappa B (NF-κB), and proteins associated with the NLRP3 inflammasome. This compound is useful for research applications focused on bacterial infections and inflammatory processes. -
Antibacterial/Antimalarial
1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid that exhibits antibacterial and antimalarial properties. This compound is derived from an Indonesian sponge and has potential applications in the study of infectious and tropical parasitic diseases. Its unique structural features may offer insights into the development of new therapeutic strategies against challenging pathogens. -
Antibacterial Agents
Cefetamet pivoxyl is a cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against a range of enteropathogens, specifically Gram-negative bacteria, with the exception of Pseudomonas aeruginosa, as well as Legionella pneumophila. This compound is primarily utilized in research related to antibacterial efficacy and the development of new antimicrobial therapies. -
Antibacterial Agent
Carumonam is a sulfonated monocyclic β-lactam antibiotic that specifically targets penicillin-binding proteins (PBPs). It demonstrates potent antibacterial activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while exhibiting limited to no inhibitory effect on Streptococcus pneumoniae and Staphylococcus aureus. Additionally, Carumonam is resistant to beta-lactamase-mediated hydrolysis, making it a valuable compound for research on antibiotic resistance and infection control studies. -
Antibacterial Agent
Pseudomonic acid C is an antibacterial agent that targets bacterial cell wall synthesis through inhibition of isoleucyl-tRNA synthetase. This compound exhibits potent antibacterial activity against various Gram-positive bacteria, making it a valuable tool for research in microbiology and antibiotic development. Its mechanism offers insights into bacterial resistance and the potential for novel therapeutic strategies. -
Antibacterial Agent
Pipemidic acid trihydrate is an antibacterial agent that targets DNA gyrase to exert its effects. This compound demonstrates activity against a range of gram-negative bacteria, including Pseudomonas aeruginosa, as well as certain gram-positive bacteria. It is suitable for research focused on intestinal, urinary, and biliary tract infections, providing a valuable tool for studying bacterial resistance and therapeutic interventions. -
Antibacterial Agent
Antibacterial Agent 104 is a potent antibacterial compound primarily targeting bacterial pathogens. Demonstrating excellent in vitro antibacterial activity, it also exhibits significant efficacy in vivo against methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research focused on developing treatments for bacterial infections and studying antibiotic resistance mechanisms. -
Bacterial Inhibitor
MT0703 is an aminothiazolyl glycyl cephalosporin that targets bacterial pathogens, exhibiting potent anti-Pseudomonas activity. This compound is studied for its potential in understanding bacterial resistance mechanisms and developing novel therapeutic strategies. Its structure, featuring a 1,5-dihydroxy-4-pyridone-2-carbonyl group, enhances its efficacy against a range of bacterial infections. -
Antibacterial
GT-1 is a siderophore-linked cephalosporin with notable antibacterial activity. It demonstrates efficacy against clinically significant isolates, including Pseudomonas aeruginosa, Klebsiella oxytoca, Proteus species, Serratia marcescens, and Enterobacter aerogenes. This compound is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Antibacterial Agent
Cefroxadine is an orally active cephalosporin antibiotic that targets bacterial cell wall synthesis. It demonstrates superior antibacterial activity compared to cephalexin against Escherichia coli and Klebsiella pneumoniae, with minimum inhibitory concentration (MIC) values of 3.13 and 1.56 μg/mL, respectively. This compound is suitable for research applications focusing on bacterial infections and antibiotic resistance mechanisms. -
Antibacterial peptide
LL-37 GKE is an antibacterial peptide derived from the active domain of LL-37. It exhibits significant antibacterial activity, making it a valuable candidate for research in antibiotic development. LL-37 GKE’s properties offer potential applications in the study of infection control and the enhancement of antimicrobial therapies. -
Anti-tumor/bacterial Agent
Napyradiomycin A1 is an enantioselective compound belonging to the napyradiomycin family, characterized by its halogenated structure. This compound exhibits significant anti-tumor and antibacterial activities, making it a valuable tool in cancer research and microbiology. Its efficacy against various tumor cell lines, along with activity against select bacterial strains, positions Napyradiomycin A1 as a promising candidate for further investigation in therapeutic applications. -
ATPase/Bacterial Inhibitor
Dihydronovobiocin is a bacterial inhibitor that targets ATPase activity by binding to the GyrB subunit of DNA gyrase. This compound is useful for investigating the interactions between coumarin antibiotics, such as Novobiocin, Chlorobiocin, and Coumermycin, and their effects on DNA gyrase function. Dihydronovobiocin also has potential applications in the study of bacterial infections, facilitating research into the mechanisms of antibiotic action and resistance. -
Antibacterial Agent
Sulfaethoxypyridazine is a sulfonamide antibacterial agent that primarily targets bacterial dihydropteroate synthase, inhibiting folate synthesis. This compound exhibits significant antibacterial activity, making it effective for use in veterinary medicine as an additive in feedstuffs. Its application is centered on the prevention and treatment of bacterial infections in livestock, enhancing animal health and productivity. -
Antimalarial/Antibacterial Agent
K-41 is an orally active antibiotic derived from Streptomyces hygroscopicus. This compound exhibits significant antibacterial and antiplasmodial activities, making it a valuable tool in research focused on infectious diseases. K-41 can be utilized in studies investigating potential treatments for malaria and bacterial infections, contributing to the development of new therapeutic strategies. -
Bacterial Inhibitor
(4-Aminobenzyl)phosphonic acid is a bioactive compound that acts as a bacterial inhibitor. It exhibits notable antibacterial and potential anticancer activities, making it useful in various research applications, particularly in the synthesis of new compounds aimed at inhibiting bacterial growth. Its unique structural properties enable effective interaction with biological targets, facilitating the exploration of novel therapeutic strategies. -
Antibacterial Agent
Mupirocin calcium is an orally active antibacterial agent derived from Pseudomonas fluorescens. It primarily functions by reversibly inhibiting isoleucyl-transfer RNA, which disrupts bacterial protein and RNA synthesis, leading to effective antimicrobial activity. This compound is utilized in research applications aimed at studying bacterial resistance mechanisms and the development of new antibacterial therapies. -
Bacterial Inhibitor
MGB-BP-3 is a bacterial inhibitor that targets multi-resistant Gram-positive pathogens. This antibiotic exhibits potent activity across a variety of clinically relevant bacterial strains, making it a valuable tool for studies focused on combating antibiotic resistance. Its broad-spectrum efficacy supports research applications in antibiotic development and microbiology. -
Antibacterial Agent
Valnemulin is a broad-spectrum antibacterial agent with efficacy against both Gram-positive and Gram-negative bacteria, as well as anaerobic bacteria, Mycoplasma, and Spirochetes. It is primarily utilized in veterinary medicine to treat enteric diseases, acute polyarthritis, and enzootic pneumonia in swine. Additionally, Valnemulin demonstrates anti-inflammatory properties, effectively mitigating lipopolysaccharide-induced lung injury in experimental models. -
Antibacterial Agent
Altromycin D is an antibiotic primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable reagent for research applications focused on the study of bacterial resistance and the development of new antimicrobial therapies. Its specific mechanism of action contributes to its efficacy in inhibiting the growth of pathogenic bacteria. -
Bacterial Inhibitor
Gramicidin C is a polypeptide antibiotic with a primary mechanism of action as a bacterial inhibitor. It disrupts bacterial cell membrane function, resulting in increased permeability that leads to cell lysis. This compound is widely utilized in microbiology research to study bacterial resistance mechanisms and to investigate antibiotic efficacy against various gram-positive and gram-negative bacteria. -
Antibacterial Agent
Antofloxacin is a potent, orally active broad-spectrum 8-amino-fluoroquinolone that serves as an antibacterial agent. It exhibits enhanced activity against gyrA mutation-positive Helicobacter pylori strains, particularly those with Asn87 mutations, outperforming levofloxacin. Additionally, Antofloxacin acts as a weak, reversible inhibitor of CYP1A2, making it a valuable tool for the study of infections caused by various bacterial species. -
Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways. -
Bacterial Inhibitor
Cefsulodin is a bacterial inhibitor primarily targeting Pseudomonas aeruginosa. It exhibits potent antimicrobial activity against penicillin-susceptible and gentamicin-sensitive strains, demonstrating effectiveness comparable to gentamicin and debendazole. However, Cefsulodin's efficacy is reduced against penicillin-resistant strains of P. aeruginosa, particularly those also resistant to gentamicin. The compound shows a similar minimum inhibitory concentration for P. aeruginosa maltofila when compared to penicillin, gentamicin, and debendazole, while Pseudomonas cepacia strains typically present moderate resistance to Cefsulodin. Its applications include evaluating bacterial resistance mechanisms and antibiotic efficacy in clinical microbiology. -
Bacterial Inhibitor
Ampicillin is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent in microbiological research and antibiotic susceptibility testing. Ampicillin is commonly used to study bacterial resistance mechanisms and is also employed in molecular biology for the selection of recombinant plasmids in cloning applications. -
Antifolate Agent, Antibacterial Agent
11-Oxahomoaminopterin is an antifolate agent that inhibits dihydrofolate reductase, targeting bacterial and tumor cell proliferation. This compound exhibits significant antibacterial activity against Lactobacillus casei, demonstrating potential applications in antimicrobial and antitumor research. Its ability to interfere with folate metabolism makes it a valuable tool for studying various biological systems. -
Antibacterial Agent
Antibacterial Agent 330 is an antibacterial compound that operates by inducing reactive oxygen species (ROS) accumulation and forming supramolecular complexes through DNA intercalation, which inhibits DNA replication. This agent disrupts bacterial metabolism by inhibiting lactate dehydrogenase (LDH) and promotes cell lysis, resulting in the leakage of intracellular contents and bacterial cell death. Antibacterial Agent 330 demonstrates significant antibacterial activity and enhances wound healing in both Galleria mellonella larval and murine models, making it a valuable tool for researching bacterial infections. -
Non-Antibacterial Macrolide Agent
Glasmacinal is a non-antibacterial macrolide agent that primarily targets inflammatory pathways. It exhibits significant anti-inflammatory activity, making it a valuable tool for researchers studying inflammation-related processes. This compound can be utilized in various biological research applications, including the exploration of immune response modulation and the development of novel therapeutic strategies. -
Anti-Bacterial Agent
Pacidamycin 7 is an anti-bacterial agent primarily targeting Pseudomonas aeruginosa. This compound exhibits inhibitory effects on various bacterial strains, including suppurative Staphylococcus and Escherichia coli. Notably, serum and pH levels can modulate its antibacterial effectiveness, making it relevant for studies focused on resistance mechanisms and antibiotic development. -
Anti-Bacterial Agent
Kibdelin C1 is a potent anti-bacterial agent that exhibits activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It demonstrates similar efficacy to Vancomycin, making it a valuable compound for research aimed at combating resistant bacterial strains. Its unique mechanism offers potential applications in the development of new therapeutic strategies against resistant infections. -
Anti-Bacterial Agent
4"-Demethylgentamicin C1a acts as an anti-bacterial agent with significant efficacy against both Gram-positive and Gram-negative bacteria. Its mechanism involves inhibition of bacterial protein synthesis, making it a valuable tool in studies related to bacterial infections. This compound is relevant for research applications in microbiology and drug development, particularly for understanding antibiotic resistance and enhancing therapeutic strategies. -
Anti-Bacterial Agent
Oganomycin B is an antibacterial agent exhibiting pronounced stability compared to cephalosporin and demonstrating resistance to both Gram-positive and Gram-negative bacteria. Its efficacy is particularly notable in combating Gram-negative bacterial strains, making it a valuable tool for research into antibacterial treatments and mechanisms of resistance. -
Antibacterial Agent
KP 736 sodium is a broad-spectrum antibacterial agent that targets bacterial cell integrity. It demonstrates significant in vitro activity against Gram-negative bacteria, particularly Pseudomonas aeruginosa and other multidrug-resistant strains. This compound is valuable for research focused on bacterial infections and the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Formadicin C is an anti-bacterial agent with notable effectiveness against various strains of Pseudomonas, Proteus, and alkali-producing bacilli. Its potent activity makes it a valuable compound for research focused on combating bacterial infections and understanding microbial resistance mechanisms. Researchers may utilize Formadicin C in studies pertaining to antibiotic efficacy and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Enaminomycin B is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound acts by disrupting bacterial cell wall synthesis, contributing to its potential as a therapeutic agent in combating bacterial infections. Enaminomycin B may be utilized in research applications focused on antibiotic resistance mechanisms and the development of new antibacterial strategies. -
Anti-Bacterial Agent
Kinamycin A is an antibacterial agent primarily targeting mycobacterial infections. It exhibits notable effects against various bacteria, while demonstrating limited efficacy against Gram-negative strains. This compound is valuable for research applications focused on the development of treatments for bacterial infections, particularly those caused by mycobacteria. -
Anti-Bacterial Agent
Quinomycin B is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria and is also effective against certain Gram-negative strains. Additionally, Quinomycin B demonstrates cytotoxic effects on HeLa cells, making it valuable in cancer research. This compound has also shown protective effects in mouse models inoculated with poliovirus, indicating potential applications in virology studies. -
Anti-Bacterial Agent
Kirrothricin is an antibacterial agent that primarily exhibits efficacy against a range of Gram-positive bacteria. It is particularly valuable in research focused on combating bacterial infections, providing insights into its use as a potential therapeutic candidate. However, it shows no activity against Bacillus subtilis, Escherichia coli, or fungal species. This specificity makes Kirrothricin a useful tool for studying antibacterial mechanisms and developing targeted treatments. -
Anti-Bacterial Agent
Cladospolide B is a natural compound derived from the fungal strain Cladosporium sp. FT-0012. It exhibits limited antibacterial activity, making it a potential candidate for further research into its mechanisms and applications in antimicrobial studies. This compound can be of interest for investigations focused on exploring novel antibacterial agents and their modes of action.
