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Antibacterial Agent
Kocurin is a thiazolyl cyclic-peptide antibiotic that primarily targets bacterial protein biosynthesis during the translation phase. It exhibits strong antibacterial activity against Gram-positive bacteria, making it a valuable reagent for research into antimicrobial resistance and the mechanisms of bacterial translation. Kocurin shows no activity against fungi or Gram-negative bacteria, highlighting its selective antibacterial profile. -
Antibacterial Agent
Cryptosporiopsin is a potent antibacterial agent derived from Cryptosporiopsis sp. and Sporormia affinis. This compound exhibits significant antibacterial activity against a variety of fungi, including basidiomycetes, algal fungi, ascomycetes, and hemiplegia fungi responsible for wood rot. Additionally, Cryptosporiopsin has been shown to inhibit the spore germination of Phytophthora species affecting potatoes, and demonstrates activity against both gram-positive and gram-negative bacteria, making it valuable for antibacterial research applications. -
Antibacterial Agent
Ticarcillin monosodium is a semisynthetic, extended-spectrum carboxypenicillin with notable antibacterial activity targeting gram-positive cocci, such as streptococci and staphylococci, as well as a broad range of gram-negative organisms, including Pseudomonas aeruginosa. This compound is utilized in research related to lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections. Its diverse spectrum of activity makes it a valuable tool for studying various infectious diseases. -
Antibacterial Agent
Gepotidacin hydrochloride is a novel antibacterial agent that inhibits bacterial type II topoisomerases. By interfering with DNA replication and repair processes, it exhibits potent activity against a range of Gram-negative and Gram-positive bacteria. This compound is primarily utilized in research focused on bacterial infections and the development of new antibacterial therapies. -
Bacterial Inhibitor
Norfloxacin hydrochloride is a broad-spectrum antibacterial agent that targets and inhibits DNA gyrase, thus interfering with bacterial DNA replication and repair. It exhibits activity against a wide range of Gram-positive and Gram-negative bacteria, making it a valuable reagent for microbiological research and the study of bacterial resistance mechanisms. This compound is utilized in the investigation of bacterial infections and the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 285 is a cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits potent antibacterial activity against gram-negative bacteria, with minimum inhibitory concentrations (MICs) of 0.125-0.5 µg/mL for carbapenem-resistant Acinetobacter baumannii, 0.125-0.5 µg/mL for Klebsiella pneumoniae, and 0.125-2 µg/mL for Pseudomonas aeruginosa. This compound is suitable for research applications related to bacterial infections, including complicated urinary tract infections and kidney infections. -
Anti-Bacterial Agent
Elaiomycin is an anti-bacterial agent that exhibits activity against Gram-positive bacteria as well as certain anaerobic bacteria. Additionally, it demonstrates efficacy against the protists Eimeria tenella and Eimeria acervulina. This compound is valuable for research applications focused on bacterial infections and parasitic control. -
Antibacterial Agent
4'-Acetyl-chrysomycin A, an analog of chrysomycin A, primarily targets bacterial cellular processes. This compound exhibits significant antibacterial activity, making it a valuable tool for antimicrobial research. Its applications include the study of antibacterial mechanisms and potential therapeutic development against bacterial infections. -
Anti-bacterial Agent
S-2,3-Dicarboxyaziridine is an antibacterial agent derived from metabolites isolated from Streptomyces species. It exhibits significant antibacterial activity, making it an important compound for research focused on microbial infections and antibiotic development. This reagent can facilitate investigations into the efficacy and mechanisms of new antibacterial therapies. -
Bacterial Inhibitor
Ceforanide (lysine) is a second-generation cephalosporin that functions as a bacterial inhibitor by interfering with bacterial cell wall synthesis. It exhibits a broad spectrum of in vitro antibacterial activity against various Gram-positive and Gram-negative bacteria. Ceforanide is primarily utilized in microbiological research to study bacterial resistance and the effects of cephalosporins on different bacterial strains. -
Antibacterial Agent
Chitotriose is a chitooligosaccharide derived from chitosan obtained from crab shells. It exhibits antibacterial activity specifically against Salmonella species. This compound is valuable for research applications in studying antimicrobial mechanisms and the development of antibacterial agents. -
Bacterial Inhibitor
Deoxypheganomycin D is a specific antimycobacterial agent that demonstrates selective inhibition of Mycobacterium 607 growth without cross-resistance to other antibiotics. At a concentration of 28 μM, it significantly reduces bacterial proliferation while showing minimal impact on DNA, RNA, or protein synthesis pathways. Notably, at 7 μM, Deoxypheganomycin D interferes with leucine influx and alters efflux dynamics, suggesting its action may involve interactions with the cell membrane and distinct mycobacterial lipid components. This reagent is valuable for researchers studying mycobacterial resistance mechanisms and developing alternative treatment strategies. -
Bacterial Quorum-sensing Molecule
N-3-Hydroxydecanoyl-DL-homoserine lactone is a bacterial quorum-sensing molecule that primarily targets the transcription factor SdiA. It activates SdiA with an EC50 value of 0.6 µM, enabling the detection of N-acyl homoserine lactones (AHLs) in bacterial systems. This compound is particularly relevant for research into the regulation of gene expression in Salmonella enterica and other bacteria, providing insights into quorum sensing mechanisms and potential therapeutic strategies against bacterial infections. -
Antibacterial Agent
Cefditoren Pivoxil hydrochloride is a third-generation oral cephalosporin antibiotic with broad-spectrum antibacterial activity, particularly effective against Gram-negative and Gram-positive bacteria. Its enhanced stability against various β-lactamases makes it a valuable tool in studying infectious diseases. Research applications include investigating acute exacerbations of chronic bronchitis, community-acquired pneumonia, streptococcal pharyngitis/tonsillitis, and uncomplicated skin and skin structure infections. -
Bacterial Inhibitor
Lysostaphin targets the bacterial cell wall, acting as an antistaphylococcal agent. This enzyme exhibits the activities of glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase, and N-acetyl muramyl-L-alanine amidase, leading to effective inhibition of Staphylococcus species. Due to its specific enzymatic action, lysostaphin is valuable in research focused on bacterial resistance, pathogen biology, and the development of antimicrobial therapeutics. -
Antibacterial Agent
Moxifloxacin is an 8-methoxyquinolone antibiotic that functions through the inhibition of bacterial DNA gyrase and topoisomerase IV. It effectively targets a variety of Gram-positive and Gram-negative bacteria, making it useful in the treatment of conditions such as acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia. This compound is valuable for research involving antimicrobial resistance and bacterial infections in clinical microbiology studies. -
Bacterial Inhibitor
Cefotaxime is a third-generation cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity against a variety of Gram-positive and Gram-negative bacteria and is notably stable against β-lactamase enzymes. This compound is widely used in microbiological research and clinical settings for the treatment and study of bacterial infections. -
Bacterial Inhibitor
Gastric mucin is a glycoprotein that acts as a bacterial inhibitor, particularly effective against Helicobacter pylori infection. It exhibits natural antibiotic properties and scavenges hydroxyl radicals, contributing to its protective role in the gastrointestinal tract. Gastric mucin plays a critical role in safeguarding against acid, proteases, and pathogenic microorganisms, while also providing defense against mechanical trauma. This functionality makes it a valuable reagent for research focused on gastrointestinal health and microbiome interactions. -
Bacterial Inhibitor
Mecillinam, a β-lactam antibiotic, primarily targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins in gram-negative organisms. It demonstrates a broad spectrum of antibacterial activity, making it valuable in studying bacterial infections and resistance mechanisms. Researchers often utilize Mecillinam for its effectiveness against various pathogenic strains, aiding in the development of therapeutic strategies and understanding bacterial physiology. -
Antibacterial Agent
Zosurabalpin is a polypeptide antibiotic that targets the LPS transporter complex (LptB2FGC), effectively inhibiting the transport of lipopolysaccharides (LPS). This mechanism leads to the accumulation of endotoxins within cells, demonstrating significant antibacterial activity against Carbapenem-resistant Acinetobacter baumannii (CRAB). Zosurabalpin serves as a valuable tool for research in antibiotic resistance and bacterial infection mechanisms. -
Bacterial Inhibitor
Cecropin A is a linear antimicrobial polypeptide composed of 37 residues that exhibits potent antibacterial activity. Additionally, it demonstrates anticancer and anti-inflammatory properties, making it a valuable tool for research in infectious diseases, cancer therapy, and inflammatory response studies. Its ability to disrupt bacterial membranes can be leveraged in the development of novel antimicrobial agents. -
Antibacterial Agent
Tebipenem is an orally available carbapenem antibiotic that exhibits broad-spectrum antibacterial activity against a variety of Gram-positive and Gram-negative bacteria, with the exception of Pseudomonas aeruginosa. It targets bacterial cell wall synthesis, making it a valuable tool in research focused on antimicrobial resistance and the development of new antibacterial therapies. Tebipenem is particularly relevant in studies aiming to characterize the pharmacodynamics and mechanisms of action of novel antibiotics. -
Bacteriostatic Antimycobacterial Agent
Ethambutol dihydrochloride is a bacteriostatic antimycobacterial agent that inhibits the activity of arabinosyltransferase, thereby preventing cell wall synthesis in Mycobacterium species. This compound is primarily utilized in research to study tuberculosis and other mycobacterial infections, as well as to establish animal models for hyperuricemia and optic neuropathy. Its mechanism and applications make it an important tool for investigating various microbial pathologies and associated therapeutic strategies. -
Bacterial Biofilm Formation Inhibitor
Ethyl acetoacetate is an ester compound that acts as an inhibitor of bacterial biofilm formation. Its unique chemical structure facilitates its role in impairing the ability of bacteria to adhere and form protective biofilms, making it a valuable research tool in studying microbial resistance and infection control. This reagent is useful in various biological applications, particularly in investigations aimed at understanding bacterial behavior and developing new antimicrobial strategies. -
Antibacterial Agent
Colistin methanesulfonate sodium salt is an antibacterial agent that primarily targets Gram-negative bacteria, including Pseudomonas aeruginosa. It demonstrates minimum inhibitory concentration (MIC) values ranging from 4 to 16 mg/L against susceptible strains, making it an essential compound for research in antimicrobial resistance and the efficacy of antibiotic treatments. This reagent is suitable for studies requiring a focus on antibiotic susceptibility and the mechanisms of action of colistin derivatives. -
Antibacterial Agent
Pectin is a heteropolysaccharide primarily derived from the cell walls of higher plants, functioning as an effective antibacterial agent. It exhibits broad-spectrum antimicrobial activity, binding to bacterial toxins and irritants in the intestinal mucosa, thereby alleviating mucosal irritation. Additionally, pectin serves as a versatile agent for the formation of nanoparticles, facilitating the delivery of therapeutic compounds. Its properties make it valuable for research in gastrointestinal health and drug delivery systems. -
Antibacterial Agent
Ceftolozane is a cephalosporin antibiotic that specifically targets bacterial infections by inhibiting cell wall synthesis. It exhibits potent antibacterial activity against Pseudomonas aeruginosa and various Enterobacteriaceae strains, with minimal inhibitory concentrations (MICs) reported at 0.5 mg/L and 0.25-0.5 mg/L, respectively. This reagent is valuable for research applications focused on antibiotic resistance and the development of new therapeutic strategies. -
Antibacterial Agent
Thiocarlide is an effective antibacterial agent primarily targeting Mycobacterium species. It demonstrates significant inhibitory activity against Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG, Mycobacterium avium, and Mycobacterium aurum A+, with minimum inhibitory concentrations (MICs) of 2.5, 0.5, 2.0, and 2.0 μg/mL, respectively. Thiocarlide can be utilized in research applications focused on tuberculosis and other mycobacterial infections. -
Antibacterial Agent
Cyclacillin is an orally active aminopenicillin antibiotic that primarily targets bacterial cell wall synthesis. It exhibits significant antibacterial activity against a broad spectrum of gram-positive and gram-negative pathogens. This compound is useful in research applications focused on infection models and the study of antibiotic resistance mechanisms. -
Antibacterial Agent
Tellimagrandin II is an antibacterial agent that disrupts the integrity of the cell wall in Staphylococcus aureus, leading to cell lysis and loss of cytoplasmic contents. Additionally, it demonstrates anti-inflammatory properties and inhibits acetylcholinesterase (AChE), which may contribute to improvements in memory impairment. This compound is of interest in research focusing on antibacterial strategies, inflammatory pathways, and neurodegenerative conditions. -
Bacterial Inhibitor
Flomoxef sodium is an oxacephem antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. It exhibits potent activity against a range of Gram-positive bacteria, making it suitable for research in antimicrobial resistance and bacterial infections. Flomoxef sodium can be utilized in studies exploring antibiotic efficacy and drug resistance mechanisms. -
Bacterial Inhibitor
Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic that inhibits bacterial protein synthesis by targeting aminoacyl-tRNA binding and peptide bond formation. As a type B compound in the streptogramin family, it exhibits potent bactericidal activity against a diverse array of Gram-positive bacteria. Virginiamycin S1, particularly in combination with virginiamycin M1, is valuable in research focused on overcoming multidrug-resistant bacterial infections. Its application is relevant in fields such as microbiology and pharmacology, particularly in the study of antibiotic efficacy and resistance mechanisms. -
Antibacterial Agent
Rosoxacin is an orally active broad-spectrum antibacterial quinolone antibiotic that primarily targets Gram-negative bacteria. It demonstrates effective inhibition against Neisseria gonorrhoeae, with a minimum inhibitory concentration (MIC) range of 0.03-0.125 µg/mL. This compound is valuable in research related to urinary tract infections and various sexually transmitted diseases, providing insights into bacterial resistance and treatment efficacy. -
Antibacterial Agent
Targocil-II is an ABC transporter inhibitor demonstrating an IC50 value of 137 nM. By binding to allosteric sites within the transmembrane domain, Targocil-II effectively prevents ATP hydrolysis. This compound exhibits antibacterial activity, making it a valuable tool for research focused on combating multidrug resistance in bacterial pathogens. -
Antibacterial Agent
CRS3123 dihydrochloride is a synthetic antibacterial agent that effectively targets methionyl-tRNA synthetase (MetRS) in Clostridioides difficile. By inhibiting MetRS, CRS3123 dihydrochloride reduces toxin production and spore formation associated with Clostridioides difficile infections (CDI). This compound serves as a valuable tool for research into CDI and potential therapeutic strategies. -
Antibacterial Agent
Temafloxacin is an orally active quinolone antibiotic that exhibits broad-spectrum antibacterial activity. Primarily utilized for the treatment of lower respiratory and genitourinary tract infections, Temafloxacin demonstrates favorable tolerability in patients. Its efficacy in combating various bacterial pathogens makes it a valuable tool in microbiological research and infection control studies. -
Antibacterial Agent
Cefpiramide is a semisynthetic cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity against both gram-positive and gram-negative bacteria, making it valuable for combating various bacterial infections. Cefpiramide is also moderately susceptible to β-lactamase, which is relevant in resistance studies and the evaluation of antibacterial efficacy. This reagent is suited for research applications in microbiology and antibiotic resistance. -
Bacterial Inhibitor
PNU-105368 is an antibacterial compound that serves as a metabolite of linezolid. It demonstrates efficacy in inhibiting bacterial growth and is primarily excreted via the kidneys and feces. This compound is relevant for research focusing on bacterial resistance and the pharmacokinetics of oxazolidinones. -
Bacterial Inhibitor
Sisomicin is a broad-spectrum aminoglycoside antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. It exhibits potent activity against Gram-positive bacteria, making it valuable in microbiological research. Sisomicin is commonly used in studies investigating bacterial resistance mechanisms and in the evaluation of antibacterial efficacy. -
Bacterial Inhibitor
Thiamphenicol-d3 is a deuterium-labeled variant of the broad-spectrum antibiotic Thiamphenicol, which targets the 50S ribosomal subunit. By binding to this subunit, it inhibits protein synthesis, exhibiting bacteriostatic activity against a wide range of Gram-negative and Gram-positive aerobic and anaerobic bacteria. This reagent is valuable for research applications involving microbiology and the study of antibiotic mechanisms. -
Bacterial Inhibitor
2,2':5',2''-Terthiophene is a heterocyclic oligomer that primarily targets bacterial inhibition. This compound exhibits significant antimicrobial activity, making it a valuable tool for studying bacterial growth and resistance mechanisms. Additionally, 2,2':5',2''-Terthiophene serves as an essential building block in the synthesis of organic semiconductor materials, particularly polythiophene, which has applications in electronic devices and sensors. -
Antibacterial agent
Lascufloxacin is a potent fluoroquinolone antibacterial agent that effectively targets bacterial DNA gyrase and topoisomerase IV, leading to DNA replication inhibition. It demonstrates significant activity against a range of pathogens, including strains resistant to traditional quinolone therapies. Lascufloxacin is primarily applicable in the treatment of various infectious diseases, particularly lower respiratory tract infections. -
Bacterial Inhibitor
Moxifloxacin hydrochloride monohydrate is a potent bacterial inhibitor that targets DNA gyrase and topoisomerase IV, leading to the disruption of bacterial DNA replication and transcription. It exhibits strong efficacy against Streptococcus pneumoniae and is primarily utilized in the study of bacterial infections, including research on tuberculosis. Its oral bioavailability and broad-spectrum activity make it a valuable reagent for microbiological studies and antibiotic efficacy testing. -
Bacterial Inhibitor
Helvolic acid, also known as Fumigacin, is a natural antibiotic derived from Xylaria sp. It exhibits potent activity against Gram-positive bacteria, making it a valuable tool for investigating bacterial inhibition. This compound can be utilized in microbiological studies to explore mechanisms of antibiotic action and resistance. -
Antibacterial Agent
SABA1 is an antibacterial agent that exhibits significant activity against Pseudomonas aeruginosa and Escherichia coli. With an IC50 of 4.0 µM against E. coli ACC, SABA1 is a valuable tool for researching bacterial infections and antimicrobial resistance in various biological studies. -
Antibacterial Agent
Mafenide is a sulfonamide-type antimicrobial agent that primarily targets bacterial nucleotide synthesis. It exhibits potent antibacterial activity against a broad spectrum of pathogens, including both Gram-positive and Gram-negative bacteria, such as Pseudomonas aeruginosa. Mafenide is commonly utilized in research related to wound healing and the treatment of burn injuries, due to its effective antimicrobial properties. -
Antibacterial Agent
Gepotidacin mesylate hydrate is an orally active antibiotic that functions as a bacterial type II topoisomerase inhibitor. It interferes with bacterial DNA replication by obstructing topoisomerase enzymes, specifically targeting topoisomerase IV and the B subunit of DNA gyrase. This compound is primarily used in research applications investigating antibacterial mechanisms and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Cefamandole is a semi-synthetic second-generation cephalosporin antibiotic that functions as a bacterial inhibitor by disrupting cell wall synthesis. It exhibits broad-spectrum antimicrobial activity against various Gram-positive cocci and several Gram-negative bacilli, while maintaining resistance to hydrolysis by certain β-lactamases. Although effective in many contexts, it shows limited efficacy against species such as Pseudomonas, Proteus vulgaris, and Providencia stuartii. Cefamandole is primarily excreted in the urine in its active form and is utilized in research applications focused on bacterial infections, although its penetration across the blood-brain barrier is minimal. -
Antibacterial Agent
Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent that inhibits dihydropteroate synthase, thereby blocking folic acid synthesis. Its antibacterial properties make it useful in various applications, including blood kinetic studies and research focused on microbial resistance mechanisms. This compound is valuable for scientists investigating the effects of folate metabolism and the therapeutic potential of sulfonamides. -
Bacterial Inhibitor
Cinnamycin is a tetracyclic peptide antibiotic that specifically targets phosphatidylethanolamine (PE). Its primary mechanism involves disrupting bacterial membrane integrity, leading to inhibition of growth in Gram-positive bacteria. Cinnamycin is commonly utilized in microbiological research to study antibiotic resistance and bacterial membrane dynamics.

