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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Fmoc-Tpi-OH is a biologically active amino acid that functions as a building block for the synthesis of antimicrobial peptide mimetics. Its unique structure allows for the development of compounds with potential antibacterial properties. This reagent is essential for research applications focused on peptide chemistry, drug design, and the exploration of new antimicrobial therapies. -
Bacterial Inhibitor
Isopsoralenoside is a benzofuran glycoside derived from Psoralea corylifolia, functioning primarily as a bacterial inhibitor. This compound exhibits estrogen-like activity, promotes osteoblastic proliferation, and demonstrates antitumor effects. Isopsoralenoside's antibacterial properties make it a valuable tool for research applications aimed at exploring microbial inhibition and associated biological processes. -
Bacterial Inhibitor
Bixafen is a pyrazole fungicide that acts as a succinate dehydrogenase inhibitor, effectively targeting and inhibiting bacterial pathogens in cereal crops. Its broad-spectrum activity makes it a valuable tool in agricultural research, helping to elucidate mechanisms of pathogen resistance and manage crop health. Bixafen's specific inhibition of succinate dehydrogenase contributes to its efficacy in various fungicidal applications. -
Bacterial Division Inhibitor
Divin, a bacterial division inhibitor, acts as a potent chelator of iron, leading to a bacteriostatic effect against both Gram-negative and Gram-positive bacteria. This compound disrupts the assembly of late division proteins, interferes with peptidoglycan remodeling at the division site, and inhibits cytoplasmic compartmentalization. Divin is valuable for research applications focused on understanding bacterial cell division mechanisms and developing new antibacterial strategies. -
Bacterial Inhibitor
Licoricone is a flavonoid derived from licorice that serves as a bacterial inhibitor. It demonstrates significant anti-Helicobacter pylori activity against both clarithromycin- and amoxicillin-resistant strains, as well as four clarithromycin- and amoxicillin-sensitive strains. This compound is valuable for research focusing on bacterial resistance and studies aimed at developing new therapeutic strategies against H. pylori infections. -
Bacterial Inhibitor
Nornidulin is a depsidone derived from Aspergillus nidulans, exhibiting significant antibacterial activity against Mycobacterium tuberculosis and Mycobacterium ranoe, as well as antifungal effects against Trichophyton tonsurans and Microsporum audouini. Additionally, it demonstrates potent inhibition of methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. Furthermore, Nornidulin displays cytotoxicity in MOLT-3 cells with an IC50 value of 35.7 μM, while exhibiting lower toxicity against HuCCA-1, HepG2, and A549 cell lines. -
Bacterial Inhibitor
3-CPs is a serotype capsular polysaccharide that inhibits antibody-mediated bacterial killing. By interfering with the immune response, it effectively reduces the phagocytosis of encapsulated bacteria. This compound is valuable for studying bacterial pathogenesis and the mechanisms of immune evasion. 3-CPs can inform research on vaccine development and therapeutic strategies aimed at combating encapsulated bacterial infections. -
Heat-inactivated Bacterial Luciferases Inhibitor
2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone-dependent refolding of heat-inactivated bacterial luciferases. By interacting with hydrophobic segments of heat-inactivated substrates, it competes with chaperones such as IbpAB. This compound is valuable for research into bacterial infections and the mechanisms of chaperone-mediated protein refolding. -
Bacterial Inhibitor
Ethyl Orsellinate is a lichen-derived metabolite and a derivative of lecanoric acid, primarily acting as a bacterial inhibitor. It exhibits notable antiproliferative and antitumor activities, making it useful in cancer research. The compound demonstrates significant cytotoxicity against A. salina, with an LC50 of 495 μM, indicating its potential as a bioactive agent in the study of microbial and tumor biology. -
Bacterial Inhibitor
EcMetAP1-IN-1 is a selective inhibitor of Escherichia coli methionine aminopeptidase 1 (MetAP1), a key enzyme involved in protein maturation. By obstructing the enzymatic activity of MetAP1, this compound effectively disrupts bacterial growth and protein synthesis, making it a valuable tool for research focused on bacterial infections and antibiotic development. Its specificity towards MetAP1 further positions EcMetAP1-IN-1 as a potential candidate for studying the mechanistic roles of methionine aminopeptidases in pathogenic bacteria. -
Bacterial Inhibitor
Urolithin M6 is a polyphenolic compound primarily recognized for its role as a bacterial inhibitor. This metabolite, synthesized through intestinal microbial metabolism, exhibits potential antioxidant properties and may function as an analogue to tannic acid compounds. Urolithin M6's production in humans necessitates the presence of specific bacterial 3-dehydroxylase activity, unveiling a novel pathway for its biotransformation. The metabolic profile of Urolithin M6 can aid in stratifying individuals for research aimed at elucidating its implications in health and disease. -
Bacterial Inhibitor
Methyl octanoate acts as a bacterial inhibitor and is recognized for its role in antimicrobial activity. This compound has applications in food preservation and can be studied for its effects on microbial growth inhibition. Additionally, it serves as a volatile aroma component in various beverages, including persimmon wine, making it of interest in both food science and microbiology research. -
Bacterial Inhibitor
NSC-79887 is a potent nucleoside hydrolase inhibitor that demonstrates significant activity against Bacillus anthracis. This compound serves as a promising candidate for biological testing and further development aimed at countering bacterial infections. Additionally, its pharmacokinetic profile suggests that all physicochemical parameters fall within acceptable ranges, indicating potential suitability for human use. -
Bacterial Inhibitor
Surgumycin is a bacterial inhibitor that exhibits notable antimicrobial activity. Its mechanism involves disrupting essential cellular processes in bacteria, making it a valuable tool for studying bacterial infections and resistance mechanisms. Surgumycin is particularly useful in research applications focused on antibiotic development and the exploration of microbial pathogenesis. -
Bacterial Inhibitor
LL-BM123α is a bacterial inhibitor derived from Nocardia sp., with a primary mechanism of action targeting Gram-negative bacteria. This compound demonstrates moderate antimicrobial activity, making it a valuable tool in research focused on bacterial infections and antibiotic resistance. LL-BM123α can be utilized in studies aimed at understanding the efficacy of novel antibiotics and developing strategies for overcoming bacterial resistance. -
Antibacterial, Biofilm Formation Inhibitor
Majoranaquinone is a potent antibacterial agent that targets various bacterial strains, demonstrating significant inhibitory effects against four Staphylococcus species, one Moraxella species, and one Enterococcus species. Additionally, it exhibits substantial efflux pump inhibitory activity in Escherichia coli ATCC 25922. Majoranaquinone also effectively inhibits biofilm formation in both E. coli ATCC 25922 and E. coli K-12 AG100, making it a valuable reagent for research applications focused on combating bacterial infections and biofilm-related challenges. -
Bacterial Inhibitor
Lauryl-LF 11 is an N-terminally acylated analogue of LF11 that acts as a bacterial inhibitor. This peptide demonstrates significant antibacterial activity, making it a valuable tool for research in microbiology and infectious diseases. It can be utilized in studies focused on the mechanisms of bacterial resistance and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Citreamicin alpha is a potent bacterial inhibitor demonstrated to exhibit significant antimicrobial activity against a range of Gram-positive cocci. In vitro studies reveal that MIC values for Staphylococci range from 0.12-4.0 μg/ml, and for Streptococcus pyogenes, they range from 0.03-0.12 μg/ml. While Citreamicin alpha shows superior efficacy compared to ampicillin, amoxicillin, and ceftriaxone, it exhibits comparable effects to vancomycin. Its effectiveness against various strains makes it a valuable reagent for research in antibiotic development and resistance studies. -
Bacterial Inhibitor
MT0703 is an aminothiazolyl glycyl cephalosporin that targets bacterial pathogens, exhibiting potent anti-Pseudomonas activity. This compound is studied for its potential in understanding bacterial resistance mechanisms and developing novel therapeutic strategies. Its structure, featuring a 1,5-dihydroxy-4-pyridone-2-carbonyl group, enhances its efficacy against a range of bacterial infections. -
ATPase/Bacterial Inhibitor
Dihydronovobiocin is a bacterial inhibitor that targets ATPase activity by binding to the GyrB subunit of DNA gyrase. This compound is useful for investigating the interactions between coumarin antibiotics, such as Novobiocin, Chlorobiocin, and Coumermycin, and their effects on DNA gyrase function. Dihydronovobiocin also has potential applications in the study of bacterial infections, facilitating research into the mechanisms of antibiotic action and resistance. -
Bacterial Inhibitor
(4-Aminobenzyl)phosphonic acid is a bioactive compound that acts as a bacterial inhibitor. It exhibits notable antibacterial and potential anticancer activities, making it useful in various research applications, particularly in the synthesis of new compounds aimed at inhibiting bacterial growth. Its unique structural properties enable effective interaction with biological targets, facilitating the exploration of novel therapeutic strategies. -
Bacterial Inhibitor
MGB-BP-3 is a bacterial inhibitor that targets multi-resistant Gram-positive pathogens. This antibiotic exhibits potent activity across a variety of clinically relevant bacterial strains, making it a valuable tool for studies focused on combating antibiotic resistance. Its broad-spectrum efficacy supports research applications in antibiotic development and microbiology. -
Bacterial Inhibitor
Gramicidin C is a polypeptide antibiotic with a primary mechanism of action as a bacterial inhibitor. It disrupts bacterial cell membrane function, resulting in increased permeability that leads to cell lysis. This compound is widely utilized in microbiology research to study bacterial resistance mechanisms and to investigate antibiotic efficacy against various gram-positive and gram-negative bacteria. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways. -
Bacterial Inhibitor
Cefsulodin is a bacterial inhibitor primarily targeting Pseudomonas aeruginosa. It exhibits potent antimicrobial activity against penicillin-susceptible and gentamicin-sensitive strains, demonstrating effectiveness comparable to gentamicin and debendazole. However, Cefsulodin's efficacy is reduced against penicillin-resistant strains of P. aeruginosa, particularly those also resistant to gentamicin. The compound shows a similar minimum inhibitory concentration for P. aeruginosa maltofila when compared to penicillin, gentamicin, and debendazole, while Pseudomonas cepacia strains typically present moderate resistance to Cefsulodin. Its applications include evaluating bacterial resistance mechanisms and antibiotic efficacy in clinical microbiology. -
Bacterial Inhibitor
Ampicillin is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent in microbiological research and antibiotic susceptibility testing. Ampicillin is commonly used to study bacterial resistance mechanisms and is also employed in molecular biology for the selection of recombinant plasmids in cloning applications. -
Bacterial Inhibitor
Resazurin sodium is a non-toxic, stable redox indicator that targets bacterial activity through its membrane-permeable properties. It serves as a vital tool for assessing cell viability, proliferation, and toxicity in various cell types, including human, plant, animal, bacterial, and fungal cells. Upon reduction, Resazurin sodium transforms into Resorufin, a highly fluorescent compound, enabling sensitive detection and quantification of cellular processes under fluorescent microscopy or spectrophotometry. -
Bacterial Inhibitor
4-Methylherniarin, a coumarin derivative, exhibits antibacterial activity by effectively inhibiting both gram-positive and gram-negative bacterial strains. It demonstrates significant antimicrobial efficacy against B. subtilis and S. sonnei, with IC50 values of 11.76 μg/ml and 13.47 μg/ml, respectively. This compound serves as a valuable tool for research applications focused on combating bacterial infections and elucidating mechanisms of action in microbial resistance. -
Bacterial Inhibitor
Procodazole is a potent bacterial inhibitor that enhances immune response, offering protection against various viral and bacterial infections. In addition to its broad-spectrum antibacterial effects, Procodazole demonstrates antiparasitic activity and serves as a carbonic anhydrase inhibitor, contributing to its antitumor properties. This compound is suitable for research applications focused on infectious diseases and cancer biology. -
Bacterial Inhibitor
Aniline-MPB-amino-C3-PBD is a cytotoxic agent targeting bacterial cells through minor-groove binding of DNA. This sequence-selective compound serves as an effective payload for antibody-drug conjugates (ADCs), enhancing their therapeutic efficacy. Its antimicrobial properties make it a valuable tool for research in bacterial inhibition and related applications. -
Bacterial Inhibitor
Py-MPB-amino-C3-PBD is a cytotoxic agent that functions as a bacterial inhibitor. This compound serves as a payload for antibody-drug conjugates (ADCs) and exhibits significant antimicrobial activity. Its unique structure, characterized by a non-alkylating group, makes it a valuable tool for research applications aimed at targeting bacterial infections and developing therapeutics in the field of microbiology. -
Bacterial Inhibitor
FR-202306 is a bacterial inhibitor that targets peptide deformylase, an enzyme crucial for bacterial protein synthesis. This compound displays significant antibacterial activity against Staphylococcus aureus by effectively inhibiting its peptide deformylase activity. FR-202306 is valuable for research applications focused on developing antibacterial agents and exploring mechanisms of bacterial resistance. -
Bacterial Inhibitor
LF11 is a peptide that functions as a bacterial inhibitor by disrupting microbial cell membrane integrity. It exhibits potent antibacterial activity, making it a valuable tool for research focused on combating bacterial infections and studying antimicrobial mechanisms. Its application is particularly relevant in the development of new therapies and understanding resistance in pathogenic bacteria. -
Bacterial Inhibitor
Rifametane is a novel 3-azamethyl-rifamycin that acts as a bacterial inhibitor. It exhibits a pharmacokinetic profile that surpasses that of rifampin, demonstrating higher peak serum concentrations in healthy volunteers. This compound is primarily used in research focused on antibacterial activity and the evaluation of new therapeutic strategies against resistant bacterial strains. -
Bacterial Inhibitor
BMS-247243 is a β-lactam antibiotic that targets methicillin-resistant Staphylococcus aureus (MRSA). It exhibits significant antibacterial activity, making it a valuable tool for research into bacterial resistance mechanisms and the development of new antimicrobial therapies. BMS-247243 is particularly relevant for studies focused on treating infections caused by resistant bacterial strains. -
Bacterial Inhibitor, Translation Inhibitor
Sancycline hydrochloride is a bacterial inhibitor that functions by reversibly binding to the 30S ribosomal subunit, thereby inhibiting protein translation. It effectively blocks the entry of aminoacyl-tRNA into the ribosomal A site, similar to other tetracycline derivatives. This semi-synthetic tetracycline, characterized by its four linearly fused six-membered rings and four stereocenters, is primarily utilized in research focusing on bacterial protein synthesis and the development of antibacterial agents. -
Bacterial Inhibitor
Celastramycin A (isomer) is an antibiotic targeting Gram-negative bacteria and Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MIC) between 0.05-3.1 μg/mL. This compound has notable immunosuppressive effects, demonstrated in Drosophila ex vivo through the immunodeficiency pathway with an IC50 of 8 ng/mL. Additionally, Celastramycin A (isomer) inhibits human innate immune responses mediated by the TNF-α pathway and reduces IL-8 production in human umbilical vein endothelial cells (HUVEC) with an IC50 of 60 ng/mL, making it a valuable reagent for research in microbiology and immunology. -
Bacterial Inhibitor
Pivmecillinam is an orally active prodrug of mecillinam, functioning primarily as a bacterial inhibitor. It exhibits potent activity against various gram-negative bacteria by interfering with the synthesis of bacterial cell walls. Pivmecillinam is utilized in research to investigate mechanisms of antibiotic resistance and the efficacy of beta-lactam antibiotics. -
Bacterial Inhibitor
Altromycin F is an anthraquinone-derived antibiotic that functions as a bacterial inhibitor by targeting and disrupting bacterial cell function. This compound exhibits significant antibacterial activity specifically against Gram-positive bacteria, including Streptococcus and Staphylococcus, with a microbial inhibitory concentration (MIC) ranging from 0.2 to 3.12 μg/mL. Altromycin F is valuable for research applications focused on understanding bacterial resistance and developing new antibacterial strategies. -
Bacterial Inhibitor
Cefoselis hydrochloride is a fourth-generation cephalosporin and a β-lactam antibiotic that targets bacterial cell wall synthesis. It demonstrates potent antibacterial activity against a broad spectrum of both Gram-positive and Gram-negative bacteria. Furthermore, cefoselis hydrochloride effectively penetrates the blood-brain barrier, making it a valuable compound for research applications in infectious diseases and central nervous system infections. -
Bacterial Inhibitor
KKL-40 is a small molecule inhibitor that targets the trans-transcription process in bacteria. It exhibits effective antibacterial activity against methicillin-sensitive and -resistant Staphylococcus aureus, as well as other Gram-positive pathogens including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. KKL-40 demonstrates a synergistic effect with the human antimicrobial peptide LL-37 against S. aureus, while showing no synergy with commonly used antibiotics such as daptomycin, kanamycin, or erythromycin. Notably, KKL-40 selectively inhibits trans-transcription without toxicity to HeLa cells, making it a valuable tool for research in bacterial genetics and antibiotic resistance. -
Bacterial Inhibitor
Norfloxacin hydrochloride is a broad-spectrum antibacterial agent that targets and inhibits DNA gyrase, thus interfering with bacterial DNA replication and repair. It exhibits activity against a wide range of Gram-positive and Gram-negative bacteria, making it a valuable reagent for microbiological research and the study of bacterial resistance mechanisms. This compound is utilized in the investigation of bacterial infections and the development of new antimicrobial therapies. -
Bacterial Inhibitor
Ceforanide (lysine) is a second-generation cephalosporin that functions as a bacterial inhibitor by interfering with bacterial cell wall synthesis. It exhibits a broad spectrum of in vitro antibacterial activity against various Gram-positive and Gram-negative bacteria. Ceforanide is primarily utilized in microbiological research to study bacterial resistance and the effects of cephalosporins on different bacterial strains. -
Bacterial Inhibitor
Deoxypheganomycin D is a specific antimycobacterial agent that demonstrates selective inhibition of Mycobacterium 607 growth without cross-resistance to other antibiotics. At a concentration of 28 μM, it significantly reduces bacterial proliferation while showing minimal impact on DNA, RNA, or protein synthesis pathways. Notably, at 7 μM, Deoxypheganomycin D interferes with leucine influx and alters efflux dynamics, suggesting its action may involve interactions with the cell membrane and distinct mycobacterial lipid components. This reagent is valuable for researchers studying mycobacterial resistance mechanisms and developing alternative treatment strategies. -
Bacterial Inhibitor
Lysostaphin targets the bacterial cell wall, acting as an antistaphylococcal agent. This enzyme exhibits the activities of glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase, and N-acetyl muramyl-L-alanine amidase, leading to effective inhibition of Staphylococcus species. Due to its specific enzymatic action, lysostaphin is valuable in research focused on bacterial resistance, pathogen biology, and the development of antimicrobial therapeutics. -
Bacterial Inhibitor
Cefotaxime is a third-generation cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity against a variety of Gram-positive and Gram-negative bacteria and is notably stable against β-lactamase enzymes. This compound is widely used in microbiological research and clinical settings for the treatment and study of bacterial infections. -
Bacterial Inhibitor
Gastric mucin is a glycoprotein that acts as a bacterial inhibitor, particularly effective against Helicobacter pylori infection. It exhibits natural antibiotic properties and scavenges hydroxyl radicals, contributing to its protective role in the gastrointestinal tract. Gastric mucin plays a critical role in safeguarding against acid, proteases, and pathogenic microorganisms, while also providing defense against mechanical trauma. This functionality makes it a valuable reagent for research focused on gastrointestinal health and microbiome interactions. -
Bacterial Inhibitor
Mecillinam, a β-lactam antibiotic, primarily targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins in gram-negative organisms. It demonstrates a broad spectrum of antibacterial activity, making it valuable in studying bacterial infections and resistance mechanisms. Researchers often utilize Mecillinam for its effectiveness against various pathogenic strains, aiding in the development of therapeutic strategies and understanding bacterial physiology. -
Bacterial Inhibitor
Cecropin A is a linear antimicrobial polypeptide composed of 37 residues that exhibits potent antibacterial activity. Additionally, it demonstrates anticancer and anti-inflammatory properties, making it a valuable tool for research in infectious diseases, cancer therapy, and inflammatory response studies. Its ability to disrupt bacterial membranes can be leveraged in the development of novel antimicrobial agents. -
Bacterial Biofilm Formation Inhibitor
Ethyl acetoacetate is an ester compound that acts as an inhibitor of bacterial biofilm formation. Its unique chemical structure facilitates its role in impairing the ability of bacteria to adhere and form protective biofilms, making it a valuable research tool in studying microbial resistance and infection control. This reagent is useful in various biological applications, particularly in investigations aimed at understanding bacterial behavior and developing new antimicrobial strategies.
