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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Pelagiomicin A is a phenazine antibiotic with a primary mechanism targeting bacterial cell functions. This compound demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool for research in microbial resistance. Additionally, Pelagiomicin A has shown promising antitumor effects in vitro and in vivo, underscoring its potential applications in cancer research. Its structure has been elucidated through a combination of spectroscopic data and synthesis techniques, contributing to the understanding of its biological properties. -
Bacterial Inhibitor
2'-Hydroxy-2-methoxychalcone acts as a bacterial inhibitor, demonstrating significant antimicrobial activity against various bacterial strains. This synthetic chalcone derivative is valuable for research in understanding bacterial resistance mechanisms and developing new antimicrobial agents. Its structural properties facilitate the exploration of structure-activity relationships in the field of medicinal chemistry. -
Bacterial Inhibitor
Chinfloxacin is a bacterial inhibitor that exerts antibacterial activity against a range of clinical isolates in vitro. Demonstrating a concentration-dependent bactericidal effect, Chinfloxacin shares antibacterial efficacy comparable to that of moxifloxacin. This compound is suitable for research applications focused on bacterial pathogenicity and the development of new antimicrobial agents. -
Bacterial Inhibitor
Phenethicillin potassium is a β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It demonstrates significant antibacterial activity against a range of Gram-positive bacteria, making it valuable in research applications focused on antimicrobial resistance and the mechanistic understanding of bacterial susceptibility. Its characteristic action profile facilitates studies in microbiology and pharmacology, providing insights into antibiotic efficacy and resistance mechanisms. -
Bacterial Inhibitor
Hikizimycin is a potent antibacterial agent that targets bacterial cell growth and division. This natural product exhibits significant antibacterial activity, making it a valuable tool for research focused on bacterial infections and their treatment. Its unique mechanism of action offers insights into new therapeutic strategies for combating antibiotic resistance. -
Bacterial Inhibitor
Antibacterial Agent 28 is a bacterial inhibitor with a mechanism targeting the growth and proliferation of pathogens such as Methicillin-resistant Staphylococcus aureus (MRSA). It exhibits antimicrobial activity with minimum inhibitory concentrations (MICs) ranging from 0.5 to 2 μg/mL. This reagent holds promise for research applications aimed at developing new treatments against resistant bacterial infections. -
Bacterial Inhibitor
β-L-Gulopyranosyl-caldarchaetidyl-glycerol (GuCGp) is a polar lipid compound targeting bacterial membranes. Its role in the lipid composition of thermoacidophilic bacteria is crucial for understanding bacterial adaptation to varying environmental conditions. This compound is valuable for research applications focused on microbial physiology and membrane biochemistry. -
Bacterial Inhibitor
Ceratotoxin B is an antibacterial peptide derived from the sexually mature females of Ceratitis capitata. It exhibits lytic and antibacterial activity, making it a valuable research tool for studying bacterial inhibition and antimicrobial mechanisms. This peptide can be utilized in studies aimed at understanding bacterial resistance and the development of novel antibacterial agents. -
Bacterial Inhibitor
TP0586352 is a potent LpxC inhibitor specifically designed to target bacterial pathogens, including carbapenem-resistant Klebsiella pneumoniae. This compound exhibits significant antibacterial activity while maintaining a favorable safety profile, as it does not pose cardiovascular risks. Additionally, TP0586352 features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions for further chemical modifications. -
Bacterial Inhibitor
Propioxatin B is a tricyclic sesquiterpenoid compound that acts as a bacterial inhibitor. This compound demonstrates significant anti-tuberculosis activity, exhibiting effectiveness against various drug-resistant Mycobacterium tuberculosis strains. In silico docking studies indicate that Propioxatin B binds with bacterial DNA gyrase, suggesting a targeted mechanism of action and potential safety in in vivo applications. -
Bacterial Inhibitor
Drimentine A is a terpenylated diketopiperazine that acts as a bacterial inhibitor, originally isolated from Actinomycete bacteria. It exhibits significant antibacterial activity, making it a valuable tool in microbiological studies. This compound is primarily utilized in research involving bacterial pathogenesis and the development of antimicrobial agents. Unlike its analogs Drimentine B and C, Drimentine A does not possess anticancer activity. -
Bacterial Inhibitor
2-C-Methyl-D-erythritol 4-phosphate is an intermediate in the methylerythritol phosphate (MEP) pathway, primarily present in prokaryotes. This compound plays a crucial role as a precursor in the biosynthesis of isoprenoids and non-isoprenoids, including essential vitamins. Its unique presence in bacteria, coupled with its absence in humans, positions it as a promising target for the development of bacterium-specific therapeutic agents for infectious disease treatment. -
Bacterial Inhibitor
Ianthelliformisamine A TFA is a bacterial inhibitor that enhances antibiotic efficacy against resistant Gram-negative bacteria. It demonstrates potent bactericidal activity against Staphylococcus aureus, with an IC50 value of 3.8 μM and a minimum inhibitory concentration of 25 μM. The biological activity is attributed to the structural variations of its synthetic derivatives and their interaction with various amino ester derivatives, making it a valuable tool for research in antibiotic resistance and bacterial infections. -
Bacterial Inhibitor
Lysine hydroxamate is an amino acid hydroxamate that acts as a bacterial inhibitor by selectively reducing the growth of Escherichia coli K-12. This compound demonstrates significant antibacterial activity among amino acid hydroxamates, with a unique mechanism of action that allows for the reversible inhibition of bacterial growth through the addition of L-serine. Lysine hydroxamate provides a valuable tool for researchers investigating bacterial growth inhibition and exploring amino acid analogs in microbial studies. -
Bacterial Inhibitor
Negamycin is a bacterial inhibitor that targets protein synthesis by binding to the head domain of the bacterial ribosomal small subunit. This interaction disrupts normal translation, leading to cell death and enhancing the misreading of near-cognate codons. Negamycin is valuable for research applications focused on understanding antibiotic mechanisms and bacterial resistance. -
Bacterial Inhibitor
3-Fluoro-DL-valine is an unnatural amino acid that functions as a bacterial inhibitor by disrupting protein synthesis in targeted bacterial strains. This compound demonstrates significant antibacterial activity, making it a valuable tool in microbiological studies. Additionally, 3-Fluoro-DL-valine can be utilized in peptide synthesis, offering versatile applications for the development of bioactive peptides in biochemical research and drug discovery. Its distinct structural properties position it as a promising candidate for innovative compound research and development. -
Bacterial Inhibitor
WQ3810 is a fluoroquinolone antibiotic that acts by inhibiting bacterial DNA gyrase and topoisomerase IV, critical enzymes for DNA replication and transcription. This compound exhibits potent antibacterial activity against a range of gram-positive and gram-negative bacteria. WQ3810 is valuable for research applications focused on studying bacterial infections and developing effective antimicrobial therapies. -
Bacterial Inhibitor
Vebufloxacin is a synthetic antibacterial agent that targets bacterial DNA gyrase, leading to the inhibition of bacterial DNA replication and transcription. It demonstrates potent activity against both gram-positive and gram-negative bacteria, making it a valuable tool in studying bacterial infections and resistance mechanisms. Research applications include evaluating the efficacy of antibacterial treatments and understanding the molecular basis of bacterial survival. -
Bacterial Inhibitor
BO3482 is a bacterial inhibitor that exhibits antimicrobial activity against methicillin-resistant Staphylococci (MRS). It demonstrates a minimum inhibitory concentration (MIC90) of 6.25 mg/mL, effectively halting bacterial growth. This compound is valuable for research applications focused on antibiotic resistance and the development of new antibacterial agents. -
Bacterial Inhibitor
A7132 is a potent antibacterial agent that targets bacterial infections. This compound exhibits broad-spectrum antibacterial activity, making it a valuable tool for research applications in antimicrobial studies and the development of new therapies against bacterial resistance. A7132 is suitable for evaluating the efficacy of antibacterial compounds in various biological assays. -
Bacterial Inhibitor
Pyrroxamycin is a novel antibiotic with a primary mechanism targeting Gram-positive bacteria and dermatophytes. Derived from the fermentation of Streptomyces, it exhibits potent antibacterial activity. This compound has potential applications in pharmaceutical research for the development of new antimicrobials, particularly against resistant bacterial strains. Detailed analysis of its chemical structure was performed using X-ray crystallography and 13C NMR spectroscopy, elucidating its physicochemical properties and enhancing its utility in microbiological studies. -
Bacterial Inhibitor
β-Lactamase-IN-6 is a potent inhibitor of β-Lactamase enzymes, which play a crucial role in bacterial resistance to β-lactam antibiotics. This compound demonstrates significant antibacterial activity by preventing the enzymatic breakdown of β-lactam antibiotics, thereby enhancing their effectiveness against resistant bacterial strains. β-Lactamase-IN-6 serves as a valuable tool in microbiological research and antibiotic development, providing insights into combating bacterial infections and resistance mechanisms. -
Bacterial Inhibitor
(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that effectively disrupts DNA supercoiling, exhibiting an IC50 of 3.3 µM. This compound demonstrates significant antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Salmonella enterica, with minimum inhibitory concentrations ranging from 10 to 80 µM. Notably, (R)-Gyramide A hydrochloride does not inhibit topoisomerase IV, making it a valuable tool for studying bacterial mechanisms and antibiotic resistance. -
Bacterial Inhibitor
Acrisorcin is a topical anti-infective compound that functions primarily as a bacterial inhibitor. It exhibits potent fungicidal properties, making it valuable for research into antifungal therapies and the understanding of bacterial resistance mechanisms. Its efficacy in mitigating fungal infections supports its application in various microbiological studies and therapeutic evaluations. -
Bacterial Inhibitor
CID21480113 is an inhibitor targeting bacterial pathways, specifically effective against dapsone-resistant strains of leprosy. This compound demonstrates significant antibacterial activity, making it a valuable tool for research in microbial resistance and infectious disease studies. Its ability to combat resistant bacteria positions CID21480113 as a relevant reagent for investigations into alternative therapies for leprosy. -
Bacterial Inhibitor
o-Cymen-5-ol acts as a broad-spectrum antimicrobial agent targeting various bacterial and fungal pathogens. It demonstrates effective minimum inhibitory concentrations (MICs) against organisms such as Streptococcus mutans and Candida albicans. Notably, o-Cymen-5-ol exhibits synergistic effects when combined with zinc, enhancing its antimicrobial activity against oral pathogens by inhibiting glycolysis. Studies indicate a more pronounced antibacterial effect in formulations such as toothpaste compared to placebo. This compound is valuable for research applications in microbiology and dental health. -
Bacterial Inhibitor
Strinoline is a bacterial inhibitor that targets and disrupts bacterial cell function. This compound exhibits significant antibacterial activity, making it a valuable tool for research in the field of microbiology. Strinoline can be utilized to study bacterial resistance mechanisms and the efficacy of antibiotic therapies. -
Bacterial IMPDH Inhibitor
IMPDH-IN-1 is a selective inhibitor of bacterial inosine 5'-monophosphate dehydrogenase (IMPDH), targeting the catalytic domain of the enzyme. This compound demonstrates potent inhibitory activity against IMPDH from key bacterial pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. It serves as a valuable tool for research into bacterial metabolism and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
4-Hydroxysphinganine (C17 base) is a bacterial inhibitor that plays a critical role in membrane structure for various organisms, including fungi, plants, and bacteria. It is essential for maintaining membrane integrity, regulating cellular growth, and facilitating the heat stress response in yeast. Additionally, 4-Hydroxysphinganine acts as a precursor for the synthesis of key lipid mediators, such as PHS 1-phosphate and inositol phosphorylceramide. Its properties also support keratinocyte differentiation, making it relevant for applications in dermatology and cosmetic research. -
Bacterial Inhibitor
Sarothralin G is a potent antibacterial compound derived from Hypericum japonicum Thunb. It exhibits exceptional activity against Gram-positive bacteria, including Staphylococcus aureus, Bacillus subtilis, and Nocardia species. With its unique phenolic and aromatic acid structure, Sarothralin G demonstrates superior antibacterial efficacy compared to related compounds such as Sarothralen A, B and Saroaspidin A, B, C. This compound is valuable for research in antibiotic development and the study of bacterial resistance mechanisms. -
Bacterial Inhibitor
INF55 is a multidrug resistance pump inhibitor targeting bacterial efflux mechanisms. By inhibiting the NoA pump, INF55 enhances the antibacterial efficacy of compounds such as berberine, reducing their efflux and overcoming bacterial resistance. Structural variants of INF55 demonstrate diverse NoA inhibitory activities, which can influence the antibacterial effectiveness of their respective heterocomplexes. This versatility makes INF55 and its derivatives valuable tools in the study and development of novel antimicrobial strategies. -
Bacterial Inhibitor
Racemomycin B is a potent bacterial inhibitor derived from Streptomyces lavendulae OP-2, characterized as a streptothricin antibiotic with three β-lysine groups. It demonstrates significant antimicrobial activity against plant pathogenic microorganisms, effectively inhibiting the root growth of Brassica rapa L. at a concentration of 50 ppm. Racemomycin B exhibits a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against various strains of Fusarium oxysporum. The biological efficacy of this compound is enhanced by the increasing number of β-lysine groups, making it a valuable tool for agricultural research. -
Bacterial Inhibitor
(R,R)-Ethambutol is a bacterial inhibitor primarily targeting Mycobacterium tuberculosis, exhibiting significant antituberculosis activity. It is commonly utilized in combination therapies to enhance the therapeutic efficacy against tuberculosis. Additionally, (R,R)-Ethambutol demonstrates effectiveness in inhibiting infections caused by Mycobacterium avium complex and Mycobacterium kansasii, making it a valuable reagent for research in mycobacterial infections. -
Bacterial Inhibitor
Fenvalerate-d6 is a deuterium-labeled derivative of Fenvalerate, primarily targeting bacterial inhibition. This compound exhibits potent antibacterial activity, making it valuable for research applications focused on elucidating bacterial resistance mechanisms and evaluating the efficacy of antibacterial agents. Its isotopic labeling enables tracking and quantification in metabolic studies and pharmacokinetic investigations. -
Bacterial Inhibitor
(E/Z)-Aureusidin is a flavonoid compound that functions as a bacterial inhibitor through its antioxidant properties. It effectively inhibits the production of reactive oxygen species, thereby reducing cellular damage and inflammation by lowering the expression of inflammatory factors. Additionally, (E/Z)-Aureusidin exhibits broad-spectrum antimicrobial activity, highlighting its potential applications in combating bacterial infections and studying inflammatory responses. -
Bacterial Inhibitor
AGS1286 sodium, an organosulfur compound, functions as a bacterial inhibitor by targeting enzymatic activities and metabolic pathways influenced by sulfur-containing compounds. This reagent is utilized in research to examine the regulatory effects on bacterial growth and gene expression, making it valuable for studies in microbiology and metabolic regulation. Its unique structural features provide insights into the role of sulfur in microbial dynamics and enzymatic processes. -
Bacterial Inhibitor
VCC234718 is a selective inhibitor of inosine monophosphate dehydrogenase (GuaB2), effectively targeting Mycobacterium tuberculosis (Mtb) to inhibit its growth. With a K value of 100 nM, VCC234718 exhibits non-competitive inhibition involving both IMP and NAD+, demonstrating its ability to disrupt enzymatic function through direct interactions with these metabolites. This compound is valuable for studying mycobacterial infections and developing new treatments for tuberculosis. -
Bacterial Inhibitor
Antitubercular agent-47 (compound 5C) is a potent bacterial inhibitor specifically targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against drug-sensitive (DS), multidrug-resistant (MDR), and extensively drug-resistant (XDR) clinical isolates. This compound is valuable for research applications focused on tuberculosis treatment and drug resistance mechanisms. -
LasB Inhibitor, Antibacterial Activity
Elastase LasB-IN-1 is a selective inhibitor of elastase LasB, exhibiting a potent IC50 value of 76 nM. This compound demonstrates significant antibacterial activity, making it an important tool for research applications focused on bacterial infections. Its specificity for LasB facilitates investigations into the role of elastolytic enzymes in microbial pathogenesis. -
Bacterial Inhibitor
Antibacterial agent 149 is a potent laccase inhibitor that exhibits significant antibacterial properties. This compound is particularly effective against bacterial pathogens and has demonstrated high fungicidal activity, making it a valuable tool for studying rice sheath blight and related diseases. Its mechanism of action and specificity enhance its utility in researching bacterial inhibition and plant pathogenic interactions. -
Bacterial Inhibitor
15-Methylhexadeca Sphinganine is an iso-branched sphingolipid that acts as a bacterial inhibitor. It is identified as a component of ceramide-containing phospholipids in bacterial cell membranes. This compound is valuable for research applications focused on understanding bacterial lipid metabolism and exploring potential therapeutic strategies against bacterial infections. -
Bacterial Inhibitor
Chevalone B is a bacterial inhibitor derived from the marine sponge-associated fungus Aspergillus similanensis. It exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as Candida albicans and multidrug-resistant environmental strains. Its potential applications in antimicrobial research highlight its significance in the development of novel therapeutic agents. -
Bacterial Ribosome Inhibitor
Capreomycin IA is a bactericidal agent that inhibits bacterial ribosomes, primarily affecting mycobacterial species. By blocking the translocation of peptidyl-transfer RNA from the A to the P site, Capreomycin IA effectively interrupts protein synthesis. This compound demonstrates significant antimicrobial activity against Mycobacterium tuberculosis and is useful for research applications related to tuberculosis and other mycobacterial infections. -
Bacterial Inhibitor
Timcodar mesylate is a bacterial efflux pump inhibitor that targets multidrug-resistant strains by directly inhibiting ethidium bromide efflux in Staphylococcus aureus. This compound enhances the effectiveness of antibiotic treatments by reducing the minimum inhibitory concentration required against Gram-positive pathogens, including Staphylococcus aureus, Enterococcus, and Streptococcus pneumoniae. Timcodar mesylate serves as a valuable tool in microbial resistance studies and antibiotic synergy research. -
Bacterial Inhibitor
Anti-MRSA agent 24 is a potent antimicrobial compound specifically targeting methicillin-resistant Staphylococcus aureus (MRSA), with particular efficacy against penicillin-resistant strains. This reagent demonstrates significant antibacterial activity, making it essential for research applications focused on combating resistant bacterial infections and studying mechanisms of antibiotic resistance. -
Bacterial Inhibitor
Streptovitacin A is a potent antibacterial agent derived from microorganisms, designed to inhibit a wide range of bacterial strains and demonstrate antiproliferative effects on tumor cells. Its primary mechanism involves interference with essential bacterial processes, making it a valuable tool in microbiological research and cancer studies. Researchers can utilize Streptovitacin A to explore bacterial resistance mechanisms and evaluate its therapeutic potential in oncology. -
Antibacterial Inhibitor
HA5 is an antibacterial inhibitor that targets biofilm formation in Streptococcus mutans. It demonstrates a potent inhibitory effect with an IC50 value of 6.42 μM, selectively disrupting biofilm structure without impacting bacterial growth. Additionally, HA5 reduces glucan production and extracellular DNA levels, making it a valuable tool for studying bacterial pathogenesis and potential therapeutic interventions in dental caries research. -
Bacterial Inhibitor
7-O-Methylaloeresin A is a 5-methylchromone glycoside isolated from Commiphora socotrana, acting primarily as a bacterial inhibitor. It demonstrates significant antimicrobial activity against methicillin-resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255), with minimum inhibitory concentrations (MIC) of 0.72 mM and 0.18 mM, respectively. Additionally, 7-O-Methylaloeresin A exhibits antioxidant properties, with IC50 values of 0.026 mM for the DPPH assay and 0.021 mM for the 2-deoxyribose degradation assay, making it useful in studies related to microbial resistance and oxidative stress. -
Bacterial Inhibitor
1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone is a bacterial inhibitor derived from the genus Garcinia. This compound exhibits significant antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentration (MIC) values of 128 μg/mL and 200 μg/mL, respectively. It serves as a valuable tool in research applications aimed at understanding bacterial resistance and developing new antimicrobial therapies. -
Bacterial Inhibitor
Urease-IN-1 is a specific urease inhibitor, demonstrated by an IC50 value of 2.21 ± 0.45 µM. This compound is primarily used for research into bacterial inhibition and is relevant for studies investigating the role of urease in microbial metabolism and pathogenesis. Further applications may include exploring its potential in controlling microbial infections associated with urease-producing bacteria.
