Catalog No.
Product Name
Application
Product Information
Citations
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Antifungal
Chloramultilide B is a lindenane dimer that exhibits potent antifungal activity. It specifically inhibits the growth of Candida albicans and Candida parapsilosis, demonstrating a minimum inhibitory concentration (MIC) of 0.068 μM. This compound can be utilized in research focused on antifungal treatments and the study of fungal pathogenesis. -
Fungal Inhibitor
Cyclo(Pro-dArg) is a potent chitinase inhibitor, primarily targeting fungal cell wall integrity. It effectively disrupts cell separation in Saccharomyces cerevisiae while having no significant impact on its overall growth. Additionally, Cyclo(Pro-dArg) inhibits the morphological transition of Candida albicans from yeast to filamentous forms, making it valuable for research in fungal biology and antifungal drug development. -
Antifungal Agent
Antifungal agent 112 (Compound 1e) primarily targets fungal pathogens, demonstrating significant antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.0024, 0.0022, and 0.0028 M, respectively. This compound is valuable for research applications focused on antifungal drug development and the study of fungal infections. Its potent efficacy may contribute to therapeutic strategies against resistant fungal strains. -
Antimicrobial Agent
3-Methoxy-2,5-toluquinone is an antimicrobial agent that exhibits moderate antibacterial and antifungal activity. It has potential applications in the study of infectious diseases and the development of novel therapeutic strategies. This compound serves as a valuable tool for researchers investigating the mechanisms of action of antimicrobial agents in various biological contexts. -
Fungicide
Ethaboxam is a β-tubulin inhibitor that effectively targets and disrupts the microtubule formation in fungi. This compound demonstrates potent anti-oomycete activity, making it a valuable tool in the study of plant-pathogenic fungi. Its mechanism of action provides insight into fungal cell division and offers potential applications in agricultural research and crop protection strategies. -
Antifungal Agent
Nitrofungin (2-Chloro-4-nitrophenol) is an antifungal agent that disrupts fungal cell membrane integrity. Its primary mechanism involves interference with ergosterol synthesis, making it a valuable tool for antifungal research. Nitrofungin is useful in studies focusing on fungal infections and the development of antifungal therapies. Additionally, it is of interest for examining microbial degradation pathways in environmental microbiology. -
Antimicrobial Drug
Somantadine is an antimicrobial agent known for its potent antimicrobial and antifungal properties. It acts by disrupting microbial cell membranes, thereby inhibiting growth and facilitating clearance of infections. This compound is valuable in research settings focused on developing therapies for bacterial and fungal infections. Its effectiveness makes it a significant candidate for studying antimicrobial resistance and evaluating new therapeutic strategies. -
Fungal
(±)-Voriconazole is a potent antifungal agent targeting fungal pathogens. It exhibits broad-spectrum activity against various fungi, including Candida and Aspergillus species, making it valuable in both clinical and research applications. This compound is primarily utilized to study antifungal resistance mechanisms and to explore novel therapeutic strategies for fungal infections. -
Antifungal Agent
Antifungal agent 143 is a potent compound primarily targeting fungal pathogens. This agent exhibits significant antifungal activity against Candida albicans and Aspergillus niger, as well as antibacterial effects against various bacterial strains including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pyogenes. Antifungal agent 143 is suitable for research applications focused on antimicrobial activity and the development of new therapeutic strategies. -
Antifungal Agent
β-Phenylethyl β-D-glucoside is a phenolic compound that serves as an antifungal agent. It exhibits significant antifungal activity against Candida albicans, making it relevant for the study of fungal infections. This compound can be isolated from the leaves of Piper crocatum and is useful in researching antifungal therapies and mechanisms. -
Immunogen Hapten
Procymidone is an immunogen hapten that serves as a crucial element for the production of polyclonal antibodies when conjugated with carrier proteins such as cOVA. This compound exhibits antifungal activity, making it valuable for research applications in immunology and toxicology, particularly in studies investigating immune responses to chemical haptens and the mechanisms of antifungal action. -
Antifungal Agent
(10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) serves as an antifungal agent and is recognized for its role as a PPARα agonist. Isolated from the basidiomycete Gomphus floccosus, it enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. This compound is suitable for research applications focused on metabolic processes and fungal inhibition. -
Antimicrobial Agent
7-(Carboxymethoxy)-4-methylcoumarin is an antimicrobial agent known for its antibacterial and antifungal properties. It exhibits inhibitory activity against a range of pathogens, including Staphylococcus aureus, Bacillus cereus, Staphylococcus luteus, Candida albicans, Candida glabrata, and Candida parapsilosis. This compound is valuable for research applications targeting microbial infections and studying antimicrobial mechanisms. -
Antifungal Agent
(Z)-Lanoconazole is an imidazole antifungal agent characterized by its Z configuration. It exhibits potent activity against a wide range of fungi, both in vitro and in vivo, by inhibiting sterol 14-alpha demethylase, thus disrupting ergosterol biosynthesis in fungal membranes. This compound is valuable for research into dermatophytosis and onychomycosis, providing insights into fungal infections and therapeutic interventions. -
Fungal Inhibitor
4-Chlorosalicylic acid is a potent fungal inhibitor that functions primarily by inhibiting monophenolase and diphenolase activities, demonstrating IC50 values of 1.89 mM and 1.10 mM, respectively. It exhibits significant antimicrobial properties, displaying an MIC of 250 μg/mL and an MBC of 500 μg/mL against E. coli. This compound is useful in research applications focused on elucidating mechanisms of fungal and bacterial inhibition. -
Aryltetralin Lignans
α-Peltatin is an aryl lignan that exhibits significant anticancer and antifungal properties. It functions primarily by inhibiting DNA topoisomerase, disrupting DNA replication and repair, and by hindering tubulin polymerization, which impairs microtubule formation. These mechanisms make α-Peltatin a valuable compound for research in cancer biology and antifungal assays. -
Fungicidal Activity
Pinosylvin monomethyl ether primarily targets fungal pathogens, exhibiting notable fungicidal activity. This compound demonstrates antibacterial effects, making it of interest for research in microbiology and pharmacology. Its applications include the study of fungal resistance and the development of antimicrobial agents. -
Antifungal Agent
iKIX1 is an antifungal agent that targets the KIX domain of the mediator subunit CgGal11A, interrupting its interaction with the activation domain of CgPdr1. This compound effectively resensitizes drug-resistant Candida glabrata to azole antifungals in vitro, with inhibition constants IC50 and Ki values of 190.2 μM and 18 μM, respectively. iKIX1 is utilized in research focused on understanding multidrug resistance mechanisms and addressing C. glabrata infections. -
Antifungal Agent
Verazine, an antifungal agent derived from the dried roots and rhizoma of Veratrum maackii Regel, targets fungal pathogens effectively. Its mechanism involves inducing DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. This compound is relevant for research applications focusing on fungal infections and neurological diseases, offering insights into their underlying mechanisms. -
Antimalarial/Antifungal Agent
Rutarin is a coumarin derivative that exhibits antimalarial and antifungal properties. It effectively inhibits Plasmodium falciparum, demonstrating an IC50 of 88 μg/mL, making it a potential candidate for malaria research. Additionally, Rutarin shows inhibitory activity against Coniophora cerebella, highlighting its utility in antifungal studies. -
Antifungal Agent
Concanamycin C is an antifungal agent that primarily targets the inhibition of lymphocyte proliferation. This compound demonstrates significant antibiotic activity against various fungal and yeast species, making it a valuable tool in antifungal research. It is particularly useful in studies exploring immune responses and fungal pathogenesis. -
Antifungal Agent
Antifungal agent 49 is an antifungal compound designed to target fungal pathogens. It exhibits potent activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM. This agent can be utilized in research focused on fungal infections and the development of novel antifungal therapies. -
Fungal Inhibitor
(E)-Coniferyl alcohol is a fungal inhibitor that acts as an intermediate in the biosynthetic pathways of eugenol, stilbenoids, and coumarin. This compound demonstrates potent activity against fungal species, making it valuable for studies focused on fungal growth inhibition. Its applications span research on plant defense mechanisms and the development of antifungal agents. -
Antifungal Agent
Diamthazole hydrochloride is an antifungal agent that targets fungal cell membranes. It has demonstrated significant activity against a range of fungal pathogens, making it a valuable tool for infection research. This compound is particularly useful in studying mechanisms of fungal resistance and evaluating potential therapeutic interventions. -
BoNT A Inhibitor
Chaetochromin A is a fungal metabolite that acts as an inhibitor of botulinum neurotoxin serotype A (BoNT A). With an IC50 value of 24.6 μM, it demonstrates significant inhibitory effects, making it a valuable tool for research into neurotoxicology and the mechanistic pathways of neurotoxin action. Its role in understanding BoNT A interactions provides insights for potential therapeutic applications. -
Antimicrobial Agent
Chlorobutanol hemihydrate functions as an antimicrobial agent, demonstrating effectiveness against a range of Gram-positive and Gram-negative bacteria, as well as various fungal spores and fungi. Its preservative properties make it suitable for applications in both the food and cosmetics industries. This compound is valuable for research involving antimicrobial resistance and preservation techniques in different biological contexts. -
Fungal Inhibitor
Isopyrazam serves as a potent fungal inhibitor, demonstrating significant efficacy against various plant pathogenic fungi. Its mechanism of action enhances disease resistance in crops, making it a valuable tool in agricultural research focused on plant protection and disease management. The use of Isopyrazam can lead to improved crop yield and quality, highlighting its potential applications in agro-biological studies. -
Mpro Inhibitor/Anti-Coronaviral Agent
Polycarpine hydrochloride is a potent inhibitor of the main protease (Mpro) with an IC50 of 30 nM, making it a valuable anti-coronaviral agent. This compound, derived from Polycarpa aurata, exhibits significant antiviral properties, demonstrating effectiveness against SARS-CoV-2 Mpro and PEDV Mpro, with IC50 values of 30.0 nM and 0.12 μM respectively. It also possesses antifungal activity, positioning it as a versatile tool for research in virology and infectious diseases. -
Antifungal Agent
Demethoxyencecalin is a chromene compound isolated from Helianthus annuus that exhibits antifungal activity. It targets fungal cell membranes, disrupting their integrity and leading to cell death. This compound is valuable for research applications focused on antifungal activity and the development of novel antifungal agents. -
Antifungal Agent
Methyl orsellinate is an antifungal agent that acts as a 5-lipoxygenase inhibitor, exhibiting an IC50 value of 59.6 μM. This phytotoxic compound demonstrates significant antifungal properties, making it a valuable tool for research on fungal infections. Its ability to inhibit key enzyme pathways highlights its potential in studying antifungal mechanisms and therapeutic applications. -
Fungal Inhibitor
Ethyl Vanillate is a potent fungal inhibitor that primarily targets 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2), with an IC50 of 1.3 µM. This compound demonstrates significant antifungal properties, making it valuable for research focused on fungal infections and related metabolic pathways. Its ability to modulate steroid hormone activity positions Ethyl Vanillate as an important tool in studies of fungal biology and therapeutic strategies. -
Fungal Inhibitor
(S,S)-Valifenalate is an acylamino acid fungicide targeting the cell-wall synthesis of Oomycetes fungi. By disrupting the structural integrity of the cell wall, it effectively hinders the growth stages of fungal pathogens, both externally on spores and internally within plant mycelium. This compound is employed in various agricultural research applications aimed at developing strategies for fungal control and improving crop health. -
Antifungal Agent
Mutanocyclin is a highly effective antifungal agent that targets Candida albicans by inhibiting its filamentation. This compound significantly reduces the mRNA expression of key genes involved in fungal morphogenesis, including HWP1, ECE1, FLO8, and TEC1. Additionally, Mutanocyclin has demonstrated the ability to inhibit the yeast form of C. albicans in ex vivo mouse models, making it a valuable tool for research on fungal pathogenesis and potential therapeutic applications. -
Fungal
(Rac)-Dehydrocostus Lactone primarily targets fungal organisms and demonstrates notable antifungal activity. This natural compound also displays a broad range of biological activities, including anti-inflammatory, anticancer, antiviral, and antimicrobial properties. Research applications include investigating its effects on Trypanosoma brucei rhodesiense, as well as exploring its potential in models of diabetes, ulcers, and helminthic infections. Additionally, (Rac)-Dehydrocostus Lactone shows varying IC(50) values in cytotoxicity assays, indicating a favorable selectivity index. -
Succinate Dehydrogenase Inhibitor
Isofetamid is a potent inhibitor of succinate dehydrogenase, primarily utilized as a fungicide. It demonstrates effective control against a range of fungal pathogens, including gray mold, white mold, and powdery mildew. This compound is valuable for research related to plant fungal diseases, contributing to the understanding of fungal inhibition mechanisms and disease management strategies. -
Rapamycin Derivative
7-O-Demethyl rapamycin, a rapamycin derivative, primarily targets the mTOR pathway. This compound exhibits antifungal activity and demonstrates immunosuppressant properties, making it valuable in research related to immune response modulation. Additionally, 7-O-Demethyl rapamycin effectively inhibits tumor cell growth, contributing to studies on cancer biology and therapeutic strategies. -
Coniferin Isomer
(E)-Coniferin is an isomer of Coniferin, a glucoside derived from coniferyl alcohol. This compound exhibits antifungal activity by inhibiting fungal growth and melanization processes. It is useful in research applications focused on fungal pathogenesis and the study of plant defense mechanisms. -
Fungicide
Fuberidazole is a potent fungicide that primarily targets fungal cell growth. It demonstrates a synergistic effect when combined with cucurbituril (CB) macromolecules, particularly CB7 and CB8, enhancing its efficacy. Research indicates that CB8 can induce pKa shifts in Fuberidazole, further improving its antifungal properties. Fuberidazole has been shown to significantly inhibit the growth of Botrytis cinerea, making it a valuable candidate for studies in agricultural and microbiological applications. -
Fungicide
Cymoxanil is a fungicidal cyanooxime that targets plant pathogens within the Perenosporales order. It exerts its biological activity by interfering with fungal growth and affecting DNA and RNA synthesis, particularly in Phytophthora species. This compound is primarily used in agricultural research to study disease management and develop protective strategies against fungal infections in crops. -
Cinnamaldehyde
3-Hydroxy-4-methoxycinnamaldehyde, a derivative of cinnamaldehyde, displays significant antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal properties with a minimum inhibitory concentration (MIC) ranging from 12.5 to 50 μg/mL. Isolated from the stem bark of Flemingia paniculata, this compound is suitable for research focused on microbial infections and the development of new antimicrobial agents. -
Antifungal Agent
Tetradehydropodophyllotoxin is an antifungal agent that exhibits potent inhibitory activity against various fungal pathogens. This compound targets key metabolic processes essential for fungal growth and survival, making it a valuable tool in antifungal research and drug development. Its application spans laboratory studies aimed at understanding fungal resistance mechanisms and evaluating antifungal efficacy. -
Fungal Inhibitor
Thalifoline is an alkaloid recognized for its antifungal properties, primarily targeting fungal cell integrity. Its mode of action involves disrupting fungal growth and proliferation, making it a valuable reagent for research focused on antifungal drug development and potential therapeutic applications against fungal infections. -
Antifungal Alkaloid
Norsanguinarine is an antifungal alkaloid that demonstrates potent activity against fungal pathogens, including Alternaria brassicicola and Curvularia maculans, at concentrations of 1000 ppm. This compound is of interest for research applications focused on the development of natural antifungal agents and the study of plant-microbe interactions. Its mechanism of action may provide insights into novel strategies for controlling fungal diseases in agricultural settings. -
Antifungal Agent
Pseudolaric acid A-O-β-D-glucopyranoside is an antifungal agent isolated from Cortex Pseudolaricis. This compound exhibits notable antifungal properties, making it valuable in research focused on fungal infections and related therapeutic strategies. Additionally, it has shown antifertility activities, providing insights into its multifaceted biological applications. -
Calcineurin Inhibitor
APX879 is a calcineurin inhibitor that selectively targets fungal cells, exhibiting reduced immunosuppressive effects and lower toxicity compared to traditional agents. As a C22-modified analog of FK506, APX879 retains broad-spectrum antifungal activity, making it a valuable tool for studying fungal pathogenesis and the immune response. It holds potential applications in antifungal drug development and research focused on fungal infections. -
Fungal Inhibitor
Saperconazole is a broad-spectrum antifungal triazole that primarily targets fungal growth by inhibiting 14α-demethylase, an enzyme essential for ergosterol biosynthesis. It exhibits potent activity against Aspergillus species, with a minimum inhibitory concentration (MIC90) of 0.19 mg/L. Saperconazole is utilized in research applications involving antifungal efficacy and mechanistic studies of fungal pathogens. -
Fungicide
Flufenoxadiazam is a fungicide that targets fungal pathogens through the inhibition of specific cellular processes. It demonstrates potent fungicidal activity, especially against Phakopsora pachyrhizi and Puccinia triticina. This compound is valuable for agricultural research aimed at managing crop diseases and improving yield in susceptible plant species. -
Fungicide
Fenbuconazole is a triazole fungicide that exerts its activity by inhibiting sterol biosynthesis in fungi. It demonstrates significant antifungal efficacy, with an ED50 of 0.21 μg/mL against M. citri and 1.01 μg/mL against C. acutatum. Additionally, Fenbuconazole has been shown to inhibit human aromatase activity in the JEG-3 choriocarcinoma cell line, leading to increased DNA damage in Allium cepa root cells and a rise in abnormal cell frequency under in vitro conditions. This compound is valuable for research in fungicidal action and mechanisms of DNA damage in cellular models. -
CHS Inhibitor
Chitin Synthase Inhibitor 4 is a selective inhibitor of chitin synthase (CHS), functioning primarily by disrupting chitin biosynthesis in fungal pathogens. This compound demonstrates significant fungicidal activity, making it a promising candidate for agricultural applications aimed at controlling fungal infections. Its mechanism supports research into chitin synthase-targeted approaches in crop protection and fungal biology.
