Catalog No.
Product Name
Application
Product Information
Citations
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Antifungal Agent
Antifungal agent 30 (compound A18) is a potent antifungal compound that targets cytochrome P450 51 (CYP51). It demonstrates significant antifungal activity against Candida albicans and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.03 and 0.5 μg/mL, respectively. This agent is particularly effective against fluconazole-resistant strains, making it a valuable tool for research in antifungal drug development and resistance mechanisms. The activity of Antifungal agent 30 is primarily attributed to its hydrogen and coordination bond interactions with CYP51. -
Depsidone
Mollicellin K is a depsidone derived from the fungus Chaetomium brasiliense, exhibiting significant antimicrobial activity. It demonstrates potent activity against Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of 12.5 μM, and strong antimalarial effects against Plasmodium falciparum (IC50 = 1.2 μM). Additionally, Mollicellin K displays antifungal properties against Candida albicans (IC50 = 1.2 μM) and cytotoxic effects against various cancer cell lines, including KB (IC50 = 1.9 μM) and BC1 (IC50 = 6.8 μM). This compound is of interest in research involving infectious diseases and cancer therapeutics. -
Anti-Cryptococcus Agent
P163-0892 is a potent anti-Cryptococcus agent that selectively targets Cryptococcus species. This compound exhibits significant antifungal activity, making it a valuable tool for research into Cryptococcus infections. Additionally, P163-0892 is predicted to demonstrate moderate blood-brain barrier (BBB) penetration, enhancing its potential applications in neurological studies related to cryptococcal diseases. -
Antifungal Agent
Pterolactam is an antifungal agent derived from Chrysanthemum coronarium L. It has demonstrated biological activity against various fungal strains and exhibits cytotoxic properties. Pterolactam and its analogues, including Mannich bases of amide, are useful for research applications aimed at understanding fungal infections and exploring potential therapeutic options in mycology. -
Antifungal Agent
Lyoniside is a lignan glycoside known for its potent antifungal properties. It effectively inhibits the mycelial growth of the fungi Fusarium oxysporum and Mucor hiemalis at a concentration of 50 μg/mL, achieving inhibition rates of 78% and 80%, respectively. Additionally, Lyoniside demonstrates antioxidant activity, with an IC50 value of 23 μg/mL in the DPPH assay, making it a valuable compound for research in antifungal development and antioxidant studies. -
Pdr1-KIX Inhibitor
Antifungal agent 72 is a selective Pdr1-KIX inhibitor that effectively suppresses efflux pump function and down-regulates resistance-related genes through disruption of the Pdr1-KIX interaction, with a Ki value of 11.7 μM. This compound demonstrates significant antifungal activity against Fluconazole-resistant strains, exhibiting a minimum inhibitory concentration (MIC) of 63 ng/mL and showing synergistic effects when used in combination with Fluconazole. Antifungal agent 72 is particularly valuable for research focused on C. glabrata infections and the development of novel antifungal strategies. -
Fungal
Janthitrem G is a fungal metabolite derived from Penicillium species, primarily acting as a potent inhibitor of fungal growth. This compound exhibits significant antifungal activity, making it valuable for research in mycology and the development of antifungal therapies. Its unique properties can aid in understanding fungal biology and resistance mechanisms. -
Anti-Plant Virus/Fungal Agent
TMV-IN-5 is an anti-plant virus and fungal agent that targets the tobacco mosaic virus (TMV) coat protein (CP). This compound inhibits viral assembly, making it a valuable tool in research aimed at developing effective pesticides for viral and fungal infections in plants. Its application can facilitate studies on plant virology and contribute to advancements in agricultural biotechnology. -
Fungal Inhibitor
Alteconazole is an azole derivative that acts as a potent antifungal agent. It exerts its action by inhibiting the enzyme lanosterol demethylase, which is essential for ergosterol synthesis in fungal membranes. This compound is valuable for research in the study of fungal pathogens and the development of antifungal therapies. Its mechanism of action makes it suitable for investigations into cellular responses to fungal infections and resistance mechanisms. -
PLA2 Inhibitor
Plipastatin B1 is a lipopeptide antibiotic that acts as an inhibitor of phospholipase A2 (PLA2). This compound exhibits antifungal activity, making it a valuable tool in investigating fungal pathogenesis and potential therapeutic interventions. It is applicable in research focusing on the modulation of PLA2-related pathways and the development of antifungal drugs. -
Fungal
Dendryphiellin D is a fungal-derived compound isolated from Septoria rudbeckiae, a plant pathogenic fungus from the halophyte Karelinia caspia. This compound is known to significantly inhibit the production of nitric oxide (NO), making it a valuable reagent for studies investigating fungal pathogenicity and host defense mechanisms. Research applications may include exploring its role in plant-microbe interactions and assessing its potential as a lead for antifungal drug development. -
SDH Inhibitor
Succinate dehydrogenase-IN-1 is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.94 μM and a KD of 22.4 μM. This compound demonstrates significant antifungal activity against various pathogens, including Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC50 values of 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively. Succinate dehydrogenase-IN-1 can be utilized in studies focusing on fungal infections and metabolic pathways involving SDH inhibition. -
Fungal Inhibitor
Antifungal Agent 120 is a potent fungal inhibitor targeting S. dermatitidis, a pathogenic fungus associated with skin infections. This reagent demonstrates significant antifungal activity and serves as a valuable tool for researchers studying fungal biology and therapeutic interventions. Further investigation may reveal efficacy against additional fungal species, expanding its potential applications in mycology research. -
Secondary Metabolite
Sporminarin A is a polyketide secondary metabolite derived from Sporormiella minimoides, demonstrating notable antifungal activity against Aspergillus flavus with a minimum inhibitory concentration (MIC50) of 25 μg/mL. Additionally, Sporminarin A exhibits antibacterial properties against Staphylococcus aureus (ATCC 29213) and antifungal effects against Candida albicans (ATCC 14053). This compound is valuable for research applications focused on microbial resistance and the development of novel antimicrobial agents. -
Polysaccharide Copolymer
L-Diguluronic acid is a linear polysaccharide copolymer consisting of two L-guluronic acid units, serving as a precursor for alginate formation. Alginate, an unbranched polyanionic polysaccharide, is utilized in various research applications, particularly in the delivery of antifungal agents. Its unique structural properties facilitate its use in drug delivery systems and biomaterials development. -
Antifungal Agent
Schidegera-saponin A1 is a spirostanol-type monosaccharide chain saponin recognized for its antifungal properties. Isolated from the stems of Yucca schidigera, it demonstrates significant inhibitory activity against food spoilage and film-forming yeasts, with a minimum inhibitory concentration (MIC) of 3.13 μg/mL against Saccharomyces cerevisiae and 6.25 μg/mL against Candida albicans. This compound is utilized in research applications aimed at studying yeast growth inhibition and food preservation strategies. -
Methoxycarbanilate Fungicide
Triclopyricarb is a methoxycarbanilate fungicide that exerts its activity by inhibiting mycelial growth in various fungal pathogens. With EC50 values ranging from 0.006 µg/mL to 0.047 µg/mL, it demonstrates potent efficacy in controlling crop diseases. This compound is primarily utilized in agricultural research for the study of fungal resistance and the development of disease management strategies. -
Antifungal Agent
Venturicidin B is a macrolide antibiotic derived from Streptomyces sp. and functions as a potent inhibitor of the mitochondrial F0-ATP synthase complex. This compound exhibits significant antifungal activity, making it useful in the research of fungal infections and mitochondrial function. Its mechanism of action provides insights into bioenergetics and the development of antifungal therapies. -
Antifungal Agent
Antifungal Agent 56 (Compound A09) is a potent antifungal agent specifically targeting Fluconazole-resistant strains. It demonstrates superior efficacy compared to Miconazole, exhibiting inhibitory activity against Candida albicans with minimum inhibitory concentration (MIC) values ranging from 0.03 to 0.25 μg/mL. This compound is valuable for research focused on overcoming antifungal resistance and developing novel treatments for fungal infections. -
Antifungal Agent
16,17-Dihydroheronamide C functions as an antifungal agent, targeting fungal growth through its unique mode of action. This compound aids in the analysis of the mechanistic pathways of heronamide C, making it an important tool for research in mycology and antifungal drug development. Its activity profile offers valuable insights into the development of new therapeutic strategies against fungal infections. -
Antifungal Agent
Antifungal Agent 76 is a potent antifungal compound that targets the fungal cell membrane leading to rapid fungicidal activity. It demonstrates a broad spectrum of antifungal activity with minimal inhibitory concentrations (MICs) ranging from 0.25 to 16 μg/mL. This compound is suitable for research applications related to antifungal drug development and studies of fungal cell membrane integrity. -
Antifungal Agent
1-Methoxyberberine chloride is a natural plant alkaloid extracted from Corydalis longipes, primarily known for its antifungal properties. This compound has demonstrated significant efficacy against various fungal strains, making it valuable for research in antifungal therapies and the study of fungal infections. Its mechanism involves disrupting fungal cell membrane integrity, thus showcasing potential applications in drug development and infectious disease research. -
Antifungal Agent
Antifungal agent 92 is a potent antifungal compound that primarily targets mitochondrial function in Sclerotinia sclerotiorum, exhibiting an EC50 of 4.4 μM. This agent disrupts mitochondrial morphology, reduces mitochondrial membrane potential, and induces the accumulation of reactive oxygen species (ROS). Additionally, antifungal agent 92 serves as a moderate inhibitor of mitochondrial complexes II and III, making it a valuable tool for research into fungal pathogenesis and mitochondrial dysfunction. -
Isochromanone
Pseudoanguillosporin A is a naturally occurring isochromanone isolated from the fungus Cadophora sp. This compound exhibits potent antifungal activity against Cryptococcus neoformans, with a minimum inhibitory concentration (MIC50) of 40 μg/mL. Pseudoanguillosporin A is suitable for research applications focused on fungal infections and the elucidation of antifungal mechanisms. -
SDH Inhibitor
Y12196 is a potent succinate dehydrogenase inhibitor (SDHI) that demonstrates strong fungicidal activity against Fusarium graminearum. This compound targets the mitochondrial metabolic pathway, disrupting energy production in fungal cells. Y12196 is valuable for investigating the role of SDH in fungal metabolism and can be utilized in studies aimed at controlling plant pathogens. -
Antibacterial/Antifungal Agent
Antibacterial Agent 288 is a targeted antibacterial and antifungal compound derived from the mangrove fungus (No. B60) found in the South China Sea. This compound exhibits significant activity against a range of bacterial and fungal pathogens, making it a valuable tool for microbiological research. Its properties may support studies in infectious disease treatment and the development of new antimicrobial agents. -
Antimicrobial
Alterlactone is an antimicrobial compound that exhibits broad-spectrum activity against both bacterial and fungal pathogens. Its ability to effectively inhibit microbial growth makes it a valuable tool in research focused on infectious diseases and antimicrobial studies. Additionally, Alterlactone demonstrates strong radical scavenging properties, contributing to its potential utility in antioxidant research. -
Inositol Derivative
2-C-methylene-myo-inositol oxide (NSC 45109) is an inositol derivative that effectively induces pseudohyphae formation in Saccharomyces species. This compound serves as a valuable tool for studying yeast morphogenesis and cellular signaling pathways related to inositol metabolism. Its unique biological activity provides insight into the physiological processes and adaptations of fungal cells. -
Opioid Receptor Agonist
Hodgkinsine is an opioid receptor agonist that exhibits significant analgesic properties while also functioning as an NMDA receptor antagonist. This compound demonstrates anti-injurial effects, making it relevant for pain management research. Additionally, Hodgkinsine possesses antiviral, antibacterial, and antifungal activities, highlighting its potential utility in various pharmacological studies. -
Antifungal Agent
1-Phenylsemicarbazide acts as an antifungal agent through its ability to inhibit fungal growth. This compound has demonstrated potential in preventing mold proliferation on various industrial products, making it valuable for applications in material preservation and quality control in diverse industries. Its effectiveness in combating fungal contamination supports further exploration in research focused on antifungal development and industrial applications. -
Antimalarial Agent
(±)-Emodin bianthrone is a natural product with potent antimalarial properties. It has demonstrated significant activity against malaria-causing pathogens, contributing to its potential in therapeutic applications. Additionally, this compound exhibits antitubercular and antifungal activities, making it a valuable reagent for research in infectious disease studies and the development of novel treatments. -
Antifungal Agent
Tetramethylkaempferol is an antifungal agent that exhibits significant activity against Candida albicans, with an IC50 value of 17.63 µg/mL. This compound is valuable for research applications focused on fungal infections and the development of antifungal therapies. Its ability to inhibit the growth of pathogenic fungi makes it an important tool for studying antifungal mechanisms and treatments. -
1,3-β-glucan Synthase Inhibitor
Arborcandin F is a potent inhibitor of 1,3-β-glucan synthase, acting as an effective antifungal antibiotic. It displays IC50 values of 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, demonstrating significant antifungal activity. Arborcandin F also exhibits a minimum inhibitory concentration (MIC) of 2-4 μg/mL against the genus Candida, making it a valuable reagent for research into fungal infections and therapeutic applications. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 7 is a potent inhibitor of chitin synthase (CHS) with an IC50 value of 0.37 mM. This compound demonstrates broad-spectrum antifungal activity, particularly against drug-resistant fungi. It is valuable for research applications focused on fungal infections and understanding the role of chitin biosynthesis in fungal pathogens. -
Antifungal Antibiotic
Amphotericin A is a potent antifungal antibiotic that exerts its activity by binding to ergosterol in fungal cell membranes, leading to increased permeability and cell death. It demonstrates strong efficacy against a variety of fungal pathogens, making it a valuable tool in research focused on fungal infections and therapeutic interventions. Its use spans studies in drug resistance, mechanism of action, and the development of novel antifungal agents. -
Antifungal Agent
(±)-Coladonin is a coumarin derivative known for its antifungal activity. It demonstrates significant inhibitory effects against the plant pathogenic fungus Botrytis cinerea, a key causative agent of gray mold disease in crops. This compound is primarily utilized in research focused on the prevention and control of fungal infections in agricultural settings. -
Antifungal Agent
trans-β-Bergamotene is a sesquiterpene hydrocarbon that acts as an antifungal agent. Isolated from the essential oil of Bixa orellana L. leaves, it exhibits both antifungal and anti-inflammatory properties. This compound is particularly useful for research focused on Candida albicans infections, providing insights into potential therapeutic applications. -
Fungicide
Antifungal agent 121 is a benzimidazole-acrylonitrile derivative that acts as a potent fungicide. It exhibits significant efficacy against a broad spectrum of fungal pathogens, making it useful for various research applications in mycology and plant pathology. This compound is valuable for studying fungal resistance mechanisms and developing antifungal treatments. -
Fungal Inhibitor
Antifungal Agent 14, a potent fungal inhibitor, demonstrates broad-spectrum activity against various fungal strains with impressive minimum inhibitory concentration values. This compound is designed for use in research applications focusing on antifungal treatment and the investigation of fungal pathogenesis, making it a valuable tool for studying fungal infections and developing therapeutic strategies. -
Antifungal Peptide
Coccinin is an antifungal peptide that exerts its bioactivity by inhibiting HIV-1 reverse transcriptase. Isolated from the seeds of large scarlet runner beans, Coccinin demonstrates significant antifungal activity against a range of pathogens, including M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus, and R. solani, with IC50 values of 75, 81, 89, 109, 122, and 134 μM, respectively. This compound is valuable for research in antifungal therapeutics and HIV-related studies. -
Antifungal Agent
Albaconazole is a broad-spectrum triazole antifungal agent that primarily targets fungal sterol synthesis by inhibiting the enzyme lanosterol demethylase. Its mechanism effectively disrupts the membrane integrity of various fungal species. This compound is utilized in research applications focused on antifungal drug development and the study of fungal infections. -
Fungicide
Pyraoxystrobin is a quinone outside inhibitor (QoI) fungicide that targets mitochondrial respiration in fungi. It demonstrates potent antifungal activity with an EC50 value of 0.0094 μg/mL against Magnaporthe oryzae isolates. This compound is valuable for research applications focused on fungal disease management in rice cultivation. -
Antifungal Peptide
KK14(R) is an analog of the synthetic antifungal peptide KK14, demonstrating potent antifungal activity against Fusarium culmorum, Penicillium expansum, and Aspergillus niger, with minimum inhibitory concentrations (MICs) of 6.25 μg/mL, 12.5 μg/mL, and 12.5 μg/mL, respectively. This compound also exhibits stability under various heat and pH conditions. Additionally, KK14(R) shows cytotoxic effects on Caco-2 and RAW264.7 cell lines, making it a valuable tool for research in fungal infections and cytotoxicity studies. -
Antimicrobial Agent
Antibacterial Agent 73 (compound 7a) is a potent antimicrobial agent targeting infectious pathogens. It demonstrates significant antitubercular activity against Mycobacterium tuberculosis H37Rv, with a minimum inhibitory concentration (MIC) of 0.65 µg/mL. Additionally, this compound exhibits effective antifungal and antibacterial properties, along with notable cytotoxic effects in MCF-7 breast cancer cell lines, displaying an IC50 of 8.20 μM. Its multifunctional bioactivity positions it as a valuable tool for exploring antimicrobial resistance and evaluating therapeutic strategies in cancer research. -
Polysaccharide Copolymer
L-Diguluronic acid disodium is a linear polysaccharide copolymer primarily targeting the formation of alginate. This compound is composed of two L-guluronic acid units and serves as a versatile unbranched polyanionic polysaccharide. Its key biological activity includes potential applications in drug delivery systems, particularly for antifungal agents. L-Diguluronic acid disodium is valuable in research exploring innovative delivery mechanisms in therapeutic formulations. -
Antimicrobial Agent
Terbinafine lactate is a potent antimicrobial agent that primarily targets squalene epoxidase, inhibiting its activity with a Ki of 30 nM in Candida species. This compound exhibits strong antifungal properties and also demonstrates antibacterial effects against specific Gram-positive and Gram-negative bacteria. Additionally, Terbinafine lactate serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. -
Antifungal Agent
Antifungal Agent 55 is a selective antifungal compound targeting resistant strains of Candida albicans. It demonstrates significant inhibitory activity with minimum inhibitory concentrations (MIC) ranging from 0.25 to 1 μg/mL, surpassing the efficacy of traditional antifungal agents. This compound is invaluable for research on antifungal resistance and the development of new therapeutic strategies against fungal infections. -
Anti-infection Agent
Monocerin is an isocoumarin derivative with properties as an anti-infection agent. Derived from the endophytic fungus Microdochium bolleyi found in Fagonia cretica, Monocerin exhibits significant antifungal, antibacterial, and antialgal activities. It has demonstrated efficacy against pathogens such as Microbotryum violaceum, Escherichia coli, Bacillus megaterium, and Chlorella fusca, making it a valuable compound for research in infectious disease studies. -
Antimicrobial Agent
Hepcidin-20 (human) is a histidine-rich, cysteine-enriched peptide with a stable β-sheet structure, functioning as an antimicrobial agent. This peptide exhibits significant antifungal properties and has been shown to inhibit biofilm formation and disrupt bacterial cell metabolism in both polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains. Its unique mechanism makes it a valuable tool for research into antimicrobial resistance and the development of novel therapeutic strategies. -
Bactericide
Ditalimfos is an organophosphate bactericide that targets a range of pathogenic fungi. It is primarily employed in agricultural applications to effectively manage fungal diseases in various crops. Additionally, Ditalimfos serves as a valuable tool for research on fungal resistance mechanisms and for conducting environmental residue risk assessments.
