Antifungal agent 100 (compound 3i) targets Succinate dehydrogenase (SDH) and demonstrates potent antifungal activity against S. sclerotiorum, with an EC50 value of 0.33 mg/L. Additionally, it displays an IC50 of 0.63 mg/mL against SDH, indicating its potential for disrupting key metabolic processes in fungal cells. This compound is particularly valuable for research applications aimed at understanding fungal pathogenesis and developing antifungal therapies.
Antifungal agent 100 (compound 3i) targets Succinate dehydrogenase (SDH) and demonstrates potent antifungal activity against S. sclerotiorum, with an EC50 value of 0.33 mg/L. Additionally, it displays an IC50 of 0.63 mg/mL against SDH, indicating its potential for disrupting key metabolic processes in fungal cells. This compound is particularly valuable for research applications aimed at understanding fungal pathogenesis and developing antifungal therapies.
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