Catalog No.
Product Name
Application
Product Information
Citations
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Antifungal Agent
D13 is an acylhydrazone derivative that exhibits potent antifungal activity. It has demonstrated effectiveness against murine sporotrichosis, making it a valuable candidate for research in fungal infections. Its unique mechanism of action and efficacy profile support its potential applications in the study and treatment of antifungal resistance and related diseases. -
Anti-Fungal Agent
Haliangicin B is an anti-fungal agent primarily targeting filamentous fungi and demonstrating efficacy against oomycetes. This compound exhibits potent biological activity, making it useful for research applications focused on fungal pathogenesis and the development of antifungal therapies. Its selective action excludes antibacterial properties, positioning it specifically within the realm of mycology research. -
Antimicrobial Agent
Terrestribisamide, also known as (E)-N,N′-Diferuloylputrescine, serves as an antimicrobial agent derived from the dried fruits of Tribulus terrestris. This compound exhibits notable antibacterial, antifungal, antioxidant, and anticancer activities, making it a valuable tool for various biological research applications. Its diverse pharmacological properties contribute to its potential in studying microbial resistance and cancer therapies. -
Isomer of Pneumocandin B0
Pneumocandin C0 is an isomer of Pneumocandin B0 known for its antifungal properties. It exhibits significant activity against fungal infections, making it suitable for research in the development of antifungal agents. Derived from the fermentation of Glarea lozoyensis under conditions of high residual fructose concentration, Pneumocandin C0 serves as a valuable compound for studies focusing on fungal pathogenesis and treatment strategies. -
Fungal Inhibitor
BHBM is an aromatic acylhydrazone compound that acts as a potent antifungal agent targeting Cryptococcus neoformans. Its high bactericidal activity makes it a valuable tool for research applications focused on fungal infections and the development of new antifungal therapies. BHBM can be used to explore mechanisms of action and resistance in fungi, contributing to advancements in infectious disease research. -
Antifungal Agent
YZK-C22 is an antifungal agent characterized by its unique 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole framework. It exhibits broad-spectrum fungicidal activity, making it a promising candidate for developing effective antifungal treatments. This compound is suitable for research applications focused on fungal pathogen control and antifungal drug discovery. -
Anti-Fungal Agent
Neocopiamycin B is an antifungal agent derived from the strain Streptomyces hygroscopicus var. crystallogenes. It exhibits potent antifungal activity against various fungal pathogens, making it a valuable tool for studying fungal infections and developing new antifungal therapies. This compound is applicable in research focused on mycology and the exploration of novel antifungal mechanisms. -
Group II introns Inhibitor
Group II intron-IN-1 acts as an inhibitor of fungal Group II introns, demonstrating an IC50 of 3 μM. This compound is valuable for research focusing on fungal infections, particularly those caused by Candida species. Its ability to selectively target intronic processes makes it a significant tool for studying fungal biology and the mechanisms of infection. -
Anti-tubercular Agent
Giparmen is an anti-tubercular agent that demonstrates significant efficacy in targeting Mycobacterium tuberculosis. This compound shows promise for further research into fungal infections, specifically those caused by Candida species. Its unique mechanism and biological activity make it a valuable tool for investigators studying tuberculosis and fungal pathogenesis. -
Antifungal
Neocryptolepine-Cl is a selective inhibitor of Bcthi4, demonstrating potent antifungal activity against Botrytis cinerea, with an EC50 value of 0.56 μg/mL. This compound is useful for research applications targeting fungal pathogens, particularly in studies investigating antifungal mechanisms and resistance. Neocryptolepine-Cl may facilitate the development of new antifungal strategies and therapies. -
Phytoalexin
Moracin B is a phytoalexin targeting fungal pathogens. This compound exhibits significant antifungal activity and can be isolated from infected mulberry (Morus alba Linne) tissues, specifically the cortex and phloem, associated with Fusarium solani f. sp. mori. Moracin B serves as a valuable tool for investigating plant disease resistance mechanisms and demonstrates potential applications in the control of plant diseases caused by microbial infections. -
Antifungal Compound
Lanomycin is an antifungal compound that targets various fungal pathogens, including Candida species and dermatophytes. It exhibits potent antifungal activity, making it suitable for research applications focused on fungal infections and therapeutic development. Lanomycin's mechanism of action can help elucidate the biology of fungal resistance and guide the discovery of novel antifungal agents. -
Antifungal Agent
8-Acetylverrucarin L is a mycotoxin with potent antifungal properties. It demonstrates significant cytotoxicity against cancer cell lines HCT116 and A2780S, exhibiting an IC100 value of 9.77 ng/mL. In addition to its antitumor effects, 8-Acetylverrucarin L shows effective antifungal activity against Saccharomyces cerevisiae, Candida albicans, and Geotrichum candidum, making it a valuable reagent for research in both cancer biology and fungal infections. -
Anti-Fungal Agent
Phoslactomycin F is an anti-fungal agent that targets fungal organisms with high efficacy. It demonstrates weak activity against Gram-positive bacteria, highlighting its specific application in fungal research. This compound can be utilized in studies exploring fungal pathogenesis and the development of novel antifungal therapies. -
Anticancer And Antimicrobial Agent
α-Thujaplicin is a potent antimicrobial agent that exhibits anticancer activity by targeting Carboxypeptidase A, with an IC50 of 32.4 μM. This compound demonstrates significant antifungal activity against various plant-pathogenic fungi, with MICs ranging from 12.0 to 50.0 μg/mL. Additionally, α-Thujaplicin shows antibacterial properties against Legionella pneumophila and Enterococcus faecalis, with respective MICs of 12.5-50 μg/mL and 1.56 μg/mL. Moreover, it inhibits the germination of Echinochloa utilis seeds and has been associated with the suppression of lymphocytic leukemia and stomach cancer. -
Broad-spectrum antifungal Agent
Pramiconazole is a broad-spectrum antifungal agent that targets 14α-demethylase, disrupting ergosterol synthesis in fungal cell membranes. It exhibits oral bioactivity and is effective against a variety of fungal infections, including those affecting the skin, hair, nails, oral cavity, and genital mucosa. This compound is valuable in research focused on antifungal therapies and the mechanisms of antifungal resistance. -
Antifungal Agent
Antifungal Agent 150 is an antifungal compound primarily targeting ergosterol biosynthesis, effectively inhibiting key enzymes involved in this pathway. It demonstrates significant activity against phytopathogenic fungi, providing lesion suppression in planta. This agent is suitable for researching plant diseases caused by Rhizoctonia solani, including banded leaf and sheath blight in maize. -
Antifungal Metabolite
Dihydrocompactin is an antifungal metabolite that acts primarily as an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase). This compound, derived from Penicillium citrinum, exhibits significant antifungal activity and is valuable in studying fungal infections and metabolic pathways. Dihydrocompactin may be used in research focused on the development of antifungal agents and the elucidation of HMG-CoA reductase's role in cellular processes. -
Antifungal Agent
Anticapsin is a potent inhibitor of glucosamine-6-phosphate synthase, functioning primarily as an antifungal agent. It exhibits efficacy against various fungal pathogens by disrupting cell wall synthesis, leading to compromised integrity and cellular death. This compound is valuable in antifungal research applications, especially in studying mechanisms of resistance and evaluating new therapeutic strategies. -
Antifungal Agent
MFB-1041 is an orally active antifungal agent that targets fungal cell function. Though it has poor oral absorption, MFB-1041 is known to facilitate the binding of the drug to serum albumin, which may enhance its efficacy. This compound is utilized in research focused on antifungal mechanisms and therapeutic development. -
Antimicrobial Agent
Concanamycin F is a specific inhibitor of V-type ATPase, exhibiting a Ki value of 0.02 nM. This compound demonstrates a range of biological activities, including antifungal, antiviral, immunosuppressive, and cytotoxic effects. It serves as a valuable tool in biochemical research, enabling investigations into cellular processes and the study of ATPase function. -
Laccase Inhibitor
Laccase-IN-6 is a potent laccase inhibitor with an IC50 of 0.097 nM. This compound demonstrates a broad-spectrum anti-fungal activity, effectively disrupting normal fungal morphology. Laccase-IN-6 is suitable for research applications focused on fungal infections and the role of laccase in pathogenicity. -
Antifungal Agent
Dihydrobiochanin A is a flavonoid with demonstrated antifungal activity. Isolated from Swartzia polyphylla, it is primarily used in research to investigate its potential as a therapeutic agent against fungal infections. Its efficacy in combating various fungal strains makes it a valuable tool in the study of antifungal mechanisms and treatments. -
Antifungal Compound
SM-4470 is an orally active antifungal compound targeting a broad spectrum of fungal pathogens. It demonstrates significant inhibitory activity against yeast, Aspergillus species, and dermatophytes in vitro. This compound is suitable for research applications focused on antifungal mechanisms and the development of novel therapeutic strategies. -
Anti-Fungal Agent
Crotocin is an anti-fungal agent that primarily targets Cryptococcus neoformans, Candida albicans, and Trichophyton species. It exhibits significant biological activity against these fungi, making it valuable for research into antifungal therapies and mechanisms of action. Notably, its efficacy may be compromised in the presence of blood, indicating potential considerations for in vivo applications. -
Anti-Fungal Agent
Maniwamycin A is an anti-fungal agent that selectively inhibits fungal growth by interfering with cellular processes. This compound exhibits potent antifungal activity against a range of fungal strains, making it valuable for studying fungal biology and testing antifungal therapies. Its application in research provides insights into fungal resistance mechanisms and potential therapeutic strategies. -
Antifungal Agent
(E)-4-Methyl-5-styrylbenzene-1,3-diol is an antifungal agent that demonstrates significant activity against various fungal pathogens. This compound is notable for its potential applications in the development of antifungal therapies, with a natural source being Dracaena cochinchinensis (Lour.) S. C. Chen. Researchers may employ this reagent to explore mechanisms of antifungal action and to evaluate its efficacy in vitro and in vivo systems. -
Antifungal Agent
Antifungal Agent 28 is a potent and selective antifungal compound that targets various pathogenic fungi. It demonstrates significant inhibitory effects against both C. albicans and non-albicans species, including strains resistant to fluconazole. Additionally, Antifungal Agent 28 effectively inhibits Cryptococcus and Aspergillus species, as well as disrupting mature biofilms formed by Candida species. This compound is valuable for researching antifungal resistance and developing new therapeutic strategies. -
Anticancer Agent
Cytovaricin is an anticancer agent that demonstrates the ability to inhibit the proliferation of Yoshida sarcoma cells. In addition to its primary activity, it exhibits modest antifungal effects against phytopathogenic fungi and shows activity against Chlorella. This compound is of interest for research applications focused on cancer cell growth inhibition and exploring potential antifungal properties. -
Sesquiterpenoid Compound
Eremofortin B is a sesquiterpenoid compound with demonstrated activity as a potent inhibitor of fungal growth. This compound exhibits significant biological effects, making it a valuable tool for research in mycology and potential applications in antifungal drug development. Its ability to disrupt cellular processes in fungi highlights its relevance for investigating new therapeutic agents against fungal infections. -
Anti-Fungal Agent
Gladiolic acid is an anti-fungal agent that exhibits potent activity against various fungal species, including Absidia glauca, Byssochlamys fulva, and Trichophyton mentagrophytes. Its efficacy in inhibiting fungal growth makes it a valuable reagent for studies focusing on fungal pathogenesis and the development of antifungal therapies. This compound can serve as a critical tool in research applications aimed at understanding fungal resistance mechanisms and exploring new antifungal strategies. -
Depsidone
Nidulin, a depsidone derived from the marine fungus Aspergillus unguis, exhibits significant antifungal and antibacterial properties. It demonstrates inhibitory activity against pathogenic strains, including Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus, and Candida albicans, with inhibition zones measuring 9.5 mm, 9.0 mm, and 9.0 mm, respectively. Additionally, Nidulin demonstrates potent larvicidal effects against brine shrimp, making it a valuable compound for research in microbial resistance and pest control. -
Anti-Fungal Agent
Chlorflavonin is an antifungal agent that targets a range of fungal pathogens, including Aspergillus, yeast, and Botrytis species. Notably, it exhibits potent activity against Aspergillus fumigatus, with a minimum inhibitory concentration determined at 0.08 μg/mL. This compound is utilized in research applications focused on fungal infection prevention and treatment. -
Antimycotic Photosensitizer
Antifungal Agent 87 is a potent photodynamic therapy (PDT) antimycotic photosensitizer, demonstrating an IC50 of 1 nM against Trichophyton rubrum. This agent induces antifungal effects through light activation, facilitating the generation of reactive oxygen species that damage fungal cells. It holds significant potential for research in fungal infections and the development of novel therapeutic approaches utilizing photodynamic mechanisms. -
Anti-Fungal Agent
Neoenactin B2 is an effective anti-fungal agent targeting yeast-like and filamentous fungi. It exhibits potent inhibitory activity against various fungal strains, making it a valuable compound for studying fungal pathogenesis and evaluating antifungal strategies. This compound is particularly useful in research applications focused on fungal infections and the development of new antifungal therapies. -
Anthraquinone Derivative
Neobulgarone C is an anthraquinone derivative derived from the fungus Neobulgaria pura HA A07-97. It is primarily known for its ability to inhibit the formation of appressorium in Magnaporthe grisea, a significant pathogen in plant biology. Additionally, Neobulgarone C exhibits weak cytotoxicity while demonstrating a lack of antifungal, antibacterial, or phytotoxic activity. This compound is relevant for research applications focused on plant-pathogen interactions and the study of fungal biology. -
Fungal
Frequentin is a secondary metabolite produced by the fungus Penicillium janthinellum, with a notable response to environmental stressors such as cadmium nitrate and sodium chloride. This compound has demonstrated significant biological activity in antifungal assays, suggesting its potential utility in investigating fungal biology and developing antifungal therapies. Research applications may include studying the effects of heavy metals and salinity on metabolite production and exploring the ecological roles of secondary metabolites in fungi. -
Antifungal agent
LY 121019 is a semi-synthetic antifungal antibiotic that exhibits potent activity against Candida species, with a minimum inhibitory concentration (MIC50) of 0.625 μg/mL. This compound is utilized in research focused on fungal infections and resistance mechanisms. Its effectiveness makes it valuable for studies aimed at understanding antifungal therapies and developing new treatment strategies. -
Antifungal Agent
Vaccarin C is a cycloheptapeptide that functions primarily as an antifungal agent. It exhibits potent antifungal activity against pathogenic fungi and dermatophytes, including M. audouinii and T. mentagrophytes, with MIC values as low as 6 µg/mL. Additionally, Vaccarin C demonstrates significant cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines, with IC50 values of 3.35 μM and 5.72 μM, respectively. This compound is useful for research applications in antifungal therapy and cancer biology. -
Anti-Fungal Agent
Clavamycin B is an anti-fungal agent with potent activity against Candida species. Its efficacy is notably antagonized by dipeptides and tripeptides, while amino acids do not affect its action. Clavamycin B does not demonstrate antibacterial activity nor inhibition of β-lactamase, making it a specific choice for studying fungal infections in laboratory settings. -
Antimicrobial Agent
Hypelcin A-I is an antimicrobial agent known for its activity against Gram-negative bacteria and fungi. It demonstrates potent inhibitory effects, making it a valuable tool for researchers studying microbial resistance and the development of new therapeutic strategies. This compound is suitable for various applications in microbiological research, particularly in evaluating antibacterial and antifungal efficacy. -
Anti-Fungal Agent
Chondramide B is an anti-fungal agent that exhibits potent activity against various fungal species, including Candida and several yeast strains such as Henson, lipids yeast, and ball-like yeast. This compound shows selective anti-fungal properties without exhibiting activity against Gram-positive or Gram-negative bacteria. Chondramide B is applicable in research focused on fungal infections and the development of antifungal therapeutics. -
Yck2 Inhibitor
GW461484A is a selective inhibitor of Candida albicans Yck2, demonstrating an IC50 of 0.11 µM. This compound exhibits significant antifungal activity, with a MIC80 of 12.5 µM against C. albicans. GW461484A is valuable for research into fungal infections, particularly those involving drug-resistant strains of Candida. -
Anti-Fungal Agent
Phoslactomycin E is an anti-fungal agent that primarily targets fungal pathogens. It exhibits potent fungicidal activity while demonstrating only limited efficacy against Gram-positive bacteria. This compound is valuable in research applications focused on fungal infections and the development of antifungal therapies. -
Chromone Compound
Isofusidienol A is a chromone compound that exhibits notable antibacterial and antifungal activities. Isolated from Artemisia vulgaris, it demonstrates significant efficacy against Bacillus subtilis and potent activity against Candida albicans. This compound is valuable for research focused on bacterial and fungal infections, providing insights into potential therapeutic applications. -
Antifungal Agent
Antifungal Agent 137 (Compound 4S) primarily targets lanosterol 14α-demethylase (CYP51) and exhibits potent antifungal activity against Phomopsis sp. (PS), with an EC50 of 0.15 μg/mL and an IC50 of 5.00 μg/mL. This compound disrupts the morphology of PS mycelia, impairs cell membrane integrity, and induces oxidative stress by increasing intracellular reactive oxygen species levels. Antifungal Agent 137 is suitable for research applications focused on fungal infections and antifungal mechanisms. -
Fungicide
Pyriofenone is an arylphenyl ketone fungicide targeting a broad spectrum of fungal pathogens. It exhibits significant activity against powdery mildew affecting crops such as cereals, rice, fruit trees, and vegetables, while also demonstrating moderate efficacy against rice blast. Its diverse action mechanisms include preventive, residual, curative, rainfast, and fumigant properties, making it an effective choice for managing fungal diseases in agricultural settings. -
Anti-Fungal Agent
Haematocin is an anti-fungal agent that specifically inhibits the germination of Pyricularia oryzae spores. This compound demonstrates significant biological activity against fungal pathogens, making it a valuable tool for research in plant pathology and antifungal drug development. Its efficacy in preventing spore germination can aid in the exploration of protective strategies against crop diseases. -
Antifungal Agent
Hordatine A is a naturally occurring compound extracted from barley, primarily known for its antifungal properties. It exhibits significant activity against a range of fungal pathogens, making it a valuable tool in the study of fungal infections. Hordatine A is suitable for research applications focused on understanding and combating fungal diseases. -
Yck2 Inhibitor
Yck2-IN-1 is a potent inhibitor of the Yck2 kinase in Candida albicans, exhibiting an IC50 of approximately 80 nM. This compound demonstrates effective antifungal activity, with a MIC80 of 12.5 µM against C. albicans and a favorable metabolic profile, retaining 66% stability in mouse liver microsomes. In preclinical studies, Yck2-IN-1 significantly reduced fungal load in the kidneys of mice with drug-resistant candidiasis, highlighting its potential for research applications in antifungal treatment development.
