Catalog No.
Product Name
Application
Product Information
Citations
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Anionic Surfactant
Sodium laureth sulfate (70% in water) is an anionic surfactant known for its versatile biological activities. This compound exhibits effective decontamination, emulsification, dispersion, and wetting properties, making it valuable for various research applications. Additionally, its antifungal capabilities expand its utility in both biotechnological and pharmaceutical studies. -
Antifungal Agent
trans-2-Hexenal is a volatile compound recognized for its antifungal properties. This compound effectively inhibits the growth of various fungal organisms and can also suppress the germination of soybean seeds and the growth of seedlings. Additionally, trans-2-Hexenal serves as a valuable reagent for the identification of low-molecular-weight carbonyl compounds that interact with biological nucleophiles in biological samples, making it useful in various research applications in plant and environmental sciences. -
Antifungal Triazole
PC945 is a potent antifungal triazole that targets the sterol 14α-demethylase enzymes CYP51A and CYP51B in Aspergillus fumigatus, demonstrating strong inhibitory activity with IC50 values of 0.23 μM and 0.22 μM, respectively. This compound exhibits efficacy against a wide variety of both azole-susceptible and azole-resistant strains of A. fumigatus. PC945 is of significant interest in antifungal research and offers potential applications in the treatment of invasive fungal infections. -
Antiseptic Agent; Fungal Inhibitor
Hexetidine, an orally active antiseptic agent, exhibits broad-spectrum antibacterial and antifungal activity. It is particularly effective in inhibiting fungal growth, especially when combined with IPBC. At concentrations exceeding 0.1%, hexetidine may lead to oral ulceration; however, it enhances plaque inhibition in conjunction with zinc. Additionally, its efficacy in treating purulent wounds has been demonstrated alongside ultrasound treatment. Hexetidine is a valuable candidate for research focusing on fungal infections and soft tissue purulent-inflammatory conditions. -
Serine Palmitoyltransferase Inhibitor
Lipoxamycin hemisulfate is a potent inhibitor of serine palmitoyltransferase, exhibiting an IC50 of 21 nM. This compound displays antifungal properties, making it valuable for research in the development of antifungal therapies. Its ability to modulate sphingolipid metabolism further supports its use in studies investigating underlying mechanisms of fungal infections and potential treatment strategies. -
Fungal Inhibitor
Myclobutanil is a systemic fungicide belonging to the conazole class that targets fungal sterol biosynthesis. It exhibits potent antifungal activity against a range of pathogenic fungi, making it valuable in agricultural applications. Myclobutanil is utilized in research for studying fungal resistance mechanisms and evaluating the efficacy of fungicides in crop protection. -
Antifungal Agent
Haloprogin is a potent antifungal agent that targets a range of fungal pathogens. It demonstrates significant activity against dermatophytes and Candida species, as well as limited efficacy against certain Gram-positive bacteria. Haloprogin is utilized in research applications focused on antifungal resistance and the development of novel antifungal treatments. -
Phytoalexin
Camalexin is a phytoalexin derived from Camelina sativa that exhibits potent antibacterial, antifungal, antiproliferative, and anticancer properties. Its mechanism of action involves the induction of reactive oxygen species (ROS) production, which contributes to its biological activity. Camalexin is utilized in research applications exploring plant defense mechanisms, as well as potential therapeutic effects against various cancers and microbial infections. -
Fungal Inhibitor
Terconazole is a broad-spectrum antifungal agent that targets fungal cell membrane synthesis. It exhibits significant activity against various Candida species, making it effective in treating vaginal yeast infections. This compound is used in research applications to study antifungal mechanisms and drug resistance in pathogenic fungi. -
ASADH Inhibitor
Naphthalene-2,3-Dicarboxaldehyde functions as a potent inhibitor of Aspergillus nidulans succinate semialdehyde dehydrogenase (ASADH), with a reported inhibition constant (Ki) of 45 μM. Its biological activity extends to inhibiting the growth of Candida albicans strain CAF2-1, exhibiting an IC50 of 58.2 μM and a minimum inhibitory concentration (MIC) of 12 μg/mL. This compound is valuable for research applications focused on antifungal mechanisms and metabolic pathway studies involving ASADH. -
Antimalarial Agent
Halofantrine hydrochloride is an antimalarial agent that primarily targets human ERG channels, inhibiting the delayed rectifier potassium current. This compound demonstrates significant antimalarial activity against Plasmodium strains in both in vitro and animal models, while also exhibiting antifungal properties by inhibiting the Cap1-dependent oxidative stress response in Candida albicans. Its effectiveness extends to enhancing the antifungal activity of agents inducing oxidative damage and is particularly relevant for research on invasive candidiasis, falciparum malaria, and vivax malaria. -
Polyene Macrolide
Lagosin is a polyene macrolide antibiotic that targets fungal cell membranes. It exhibits broad-spectrum antifungal activity, making it effective against various fungal pathogens. Due to its unique mechanism of action, Lagosin remains resistant to many common antifungal resistance mechanisms, making it a valuable reagent for research in mycology and antifungal drug development. -
Antifungal Agent
Nikkomycin Z is a nucleoside peptide that functions as an orally active antifungal agent. It acts as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine, thereby inhibiting chitin synthesis. This mechanism contributes to its notable antifungal activity, making Nikkomycin Z a valuable tool for research in fungal infections and chitin metabolism. -
Glucanase
Endo-1,3-β-glucanase is an endoenzyme that specifically targets β-1,3-glycosidic bonds within glucan chains. Its catalytic activity hydrolyzes polysaccharides into oligosaccharides, making it valuable in research focused on fungal infections, notably Candida spp. This enzyme is particularly applicable in studies related to recurrent Candida vaginitis, where it can aid in understanding the pathogen's cell wall composition and potential therapeutic strategies. -
β-1,3-glucan Inhibitor
Ibrexafungerp citrate is a potent β-1,3-glucan synthesis inhibitor with promising antifungal properties. This compound demonstrates efficacy against a range of fungal infections, specifically targeting Candida and Aspergillus species. Ibrexafungerp citrate is currently under investigation for its therapeutic potential in the treatment of these serious infections. -
Antifungal Agent
4-Isopropylbenzoic acid is an aromatic monoterpenoid known for its antifungal properties. Isolated from the stem bark of Bridelia retusa, this compound demonstrates significant activity against various fungal strains. Additionally, it acts as a reversible and uncompetitive inhibitor of mushroom tyrosinase, making it relevant in studies related to enzymatic inhibition and fungal pathogen research. -
Fungal Inhibitor
Paclobutrazol is a triazole-based compound that functions primarily as a fungal inhibitor by disrupting the biosynthesis of gibberellins. Its antifungal properties make it useful in investigating plant-pathogen interactions and enhancing plant resilience. Additionally, Paclobutrazol can suppress abscisic acid synthesis and promote chilling tolerance in various plant species, supporting research into plant stress responses and growth regulation. -
HER2 Ligand
Camelliaside A is a phytochemical that functions as a HER2 ligand. It plays a significant role in breast cancer-related research, contributing to the understanding of HER2 signaling pathways. Notably, Camelliaside A does not exhibit antifungal activity against the pathogen Rhizoctonia solani, demonstrating its specificity in targeting HER2 without adversely affecting mycelial growth. -
Anticancer/antifungal Agent
Echinoside A is a saponin that primarily targets Topoisomerase II alpha (Top2α), inhibiting its catalytic activity and reducing its noncovalent binding to DNA. This compound activates Caspase-3 and induces PARP cleavage, thereby promoting apoptosis. Echinoside A exhibits significant anticancer properties against various cancers, including prostate cancer, hepatocellular carcinoma, and S-180 sarcoma. Additionally, it displays antifungal activity across a spectrum of fungi, with a minimum inhibitory concentration ranging from 3.12 to 50.0 μg/mL, demonstrating particularly strong effects against Aspergillus and Penicillium species. -
Histone Acetyltransferase Inhibitor
Rtt109 inhibitor 1 is a potent inhibitor of the histone acetyltransferase Rtt109, functioning through a tight-binding, uncompetitive mechanism. This compound demonstrates significant antifungal activity by specifically targeting acetylation at the H3K56 site. Rtt109 inhibitor 1 is suitable for research applications focused on histone modifications and their roles in fungal pathogenesis. -
HDM Inhibitor
HDM-IN-1 is a potent inhibitor of histone demethylases (HDM), specifically targeting H3K27me3 methylation in fungal pathogens such as Cryptococcus neoformans and Candida auris, with IC50 values of 134 nM and 12 nM, respectively. This compound demonstrates significant antifungal activity, achieving MIC80 values between 0.5-2 μg/mL by disrupting biofilm and capsule formation. In vivo studies in an ICR mouse model further confirm its efficacy as an antifungal agent. HDM-IN-1 is a valuable tool for research on histone modifications and their implications in fungal virulence and drug resistance. -
Antifungal Agent
Fluconazole is a triazole antifungal agent that primarily targets fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. It exhibits potent activity against a wide spectrum of fungi, particularly Candida albicans and Candida kefyr, with IC99 values ranging from 0.20 μg/mL to 0.39 μg/mL. Fluconazole is widely utilized in research to study fungal pathogenesis and develop therapeutic strategies against fungal infections. -
Antifungal Agent
Miconazole is an imidazole antifungal agent that acts through the inhibition of ergosterol synthesis, disrupting fungal cell membrane integrity. In addition to its antifungal properties, Miconazole exhibits antibacterial effects, making it a versatile compound in microbiological studies. This reagent is commonly utilized in research focusing on antifungal therapies and mechanisms of microbial resistance. -
Antifungal Agent
Miconazole nitrate is an imidazole antifungal agent that exhibits its primary mechanism through the inhibition of ergosterol synthesis, leading to compromised fungal membrane integrity. This compound demonstrates significant antifungal activity against a broad spectrum of fungi, making it valuable for research in antifungal drug development and therapeutic applications. Additionally, Miconazole nitrate possesses antibacterial properties, contributing to its utility in studies related to infections and microbial resistance. -
Antimicrobial Agent
Terbinafine is a potent antimicrobial agent that primarily acts as a non-competitive inhibitor of squalene epoxidase, exhibiting a Ki of 30 nM against Candida species. This compound demonstrates significant antifungal activity and also shows antibacterial effects against select Gram-positive and Gram-negative bacteria. Additionally, Terbinafine features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) for versatile chemical applications in research. -
Antifungal Agent
Oxiconazole nitrate is a broad-spectrum antifungal agent targeting various fungal pathogens, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, it acts as a potent activator of CYP3A4 transactivation, with the potential for competitive antagonism by Rifampicin. Furthermore, Oxiconazole nitrate exhibits inhibitory effects against colorectal cancer through mechanisms involving peroxiredoxin-2 (PRDX2)-mediated autophagy arrest, making it valuable for research in both antifungal therapy and cancer biology. -
Squalene Epoxidase Inhibitor
Liranaftate is a potent squalene epoxidase inhibitor exhibiting anti-fungal properties. It is primarily utilized in research focusing on dermatophyte infections. Additionally, Liranaftate has been shown to suppress the fungal element-mediated production of interleukin-8 (IL-8) and modulate inflammatory responses, making it valuable for studies involving inflammatory pathways in fungal infections. -
Antifungal Agent
Gartanin is a natural xanthone derived from mangosteen, primarily functioning as an antifungal agent. It exhibits significant antioxidant and anti-inflammatory properties, alongside neuroprotective and antineoplastic effects. Gartanin has been shown to induce cell cycle arrest and autophagy, while also inhibiting migration in human glioma cells, making it a valuable compound for research in cancer and fungal pathologies. -
Fungal Inhibitor
Pseudolaric Acid C is a bioactive diterpenoid derived from the root bark of Pseudolarix amabilis, primarily acting as a fungal inhibitor. It exhibits significant antifungal activity, making it a valuable tool for research focused on fungal pathogenesis and the development of antifungal therapies. Its ability to disrupt fungal growth positions it as an important compound in the study of mycology and related fields. -
Fungal Inhibitor
5-Hydroxymethylfurfural is a furan derivative that serves as a potent fungal inhibitor. It exhibits anti-yeast activity by suppressing growth and fermentation under stress conditions, making it valuable for studies related to microbial resistance and fermentation processes. This compound is utilized in research focused on food preservation and biotechnological applications. -
Bactericidal Agent
Terpinen-4-ol, a naturally occurring monoterpene, acts primarily as a bactericidal agent. This compound exhibits significant antifungal, anti-inflammatory, and antitumor activities, making it a valuable tool for diverse research applications, especially in the study of microbial resistance and inflammation. Its multiple biological effects also support investigations into potential therapeutic uses in various diseases. -
Bicyclic Sesquiterpene
Caryophyllene oxide is a bicyclic sesquiterpene known for its anticancer properties, particularly its ability to induce apoptosis in PC-3 prostate cancer cells. This compound also exhibits significant analgesic and anti-inflammatory activities, making it valuable for pain management research. Additionally, caryophyllene oxide demonstrates a range of biological activities, including insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic effects, supporting its utility in various pharmacological studies and natural product research. -
Anti-Fungal Agent
Hypocrellin B is a photosensitizer with significant apoptotic properties, primarily used in photodynamic therapy for cancer treatment. Isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, it exhibits both antimicrobial and antileishmanial activities. This compound is valuable in research exploring its efficacy against various fungal infections and its potential therapeutic applications in oncology. -
Antifungal Agent
4-Methylcinnamic acid is a cinnamic acid derivative primarily known for its antifungal properties. This compound demonstrates the capability to enhance the efficacy of traditional antifungal agents by lowering their minimum inhibitory concentrations, particularly in the presence of glutathione reductase mutants. Its mechanism includes disrupting fungal cell walls, making it a promising candidate for research into combating drug-resistant fungi. 4-Methylcinnamic acid shows potential applications in the development of more effective antifungal therapies. -
Antifungal Agent
Vincetoxicoside B is an antifungal agent that exhibits potent activity against various fungal pathogens. This compound can be utilized in research focused on fungal infections and the development of new therapeutic strategies. Its mechanism of action and efficacy make it a valuable tool in the study of antifungal mechanisms and resistance. -
Fungal Inhibitor
Hecogenin is a steroid saponin derived from Agave sisalana, known for its selective inhibition of human UDP-glucuronosyltransferases. It exhibits a diverse range of biological activities, particularly as a potent antifungal agent, while also demonstrating anti-inflammatory and gastroprotective properties. Hecogenin is of interest in pharmacological research for its potential therapeutic applications in treating fungal infections and inflammatory conditions. -
Cytochrome P450 1A1 Inactivator
Rhapontigenin is a potent and selective inactivator of cytochrome P450 1A1, demonstrating an IC50 of 400 nM. This natural analog of resveratrol exhibits significant anticancer, antioxidant, antifungal, and antibacterial properties. Due to its 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively, Rhapontigenin is a valuable tool for research focused on cancer biology and drug metabolism. -
Antifungal Agent
Xanthoxylin, an antifungal agent derived from Zanthoxylum simulans, exhibits notable antifungal and antioxidant properties. It demonstrates minimum inhibitory concentrations (MIC) of 50 µg/mL against Toxoplasma neonatorum and 75 µg/mL against Aspergillus fumigatus. This compound is valuable for investigating antifungal therapies and exploring potential applications in the context of anti-epileptic diseases. -
Antibacterial/Antifungal agent
Dehydroacetic acid is a pyrone derivative known for its antibacterial and antifungal properties. This compound exhibits significant phytotoxic activity, making it a valuable agent in various applications such as preservation in cosmetics, food, and beverages. Additionally, dehydroacetic acid serves as a precursor in the synthesis of various heterocycles and cycloaddition products, providing utility in chemical research and development. -
Antifungal Agent
Sertaconazole nitrate is a broad-spectrum topical antifungal agent that primarily targets fungal infections. In addition to its antifungal properties, it exhibits anti-inflammatory activity through the activation of the p38-COX-2-PGE2 pathway. Sertaconazole nitrate also acts as a microtubule inhibitor, demonstrating antiproliferative effects, as well as the ability to induce apoptosis and autophagy. Furthermore, it can inhibit cell migration, making it valuable for various research applications in mycology and cellular biology. -
Antifungal Agent
Sulconazole mononitrate is an imidazole derivative that acts as a broad-spectrum antifungal agent. It exhibits significant efficacy against various fungal infections, making it useful for research related to dermatomycoses, pityriasis versicolor, and cutaneous candidiasis. This compound can facilitate studies aimed at understanding the mechanisms of fungal resistance and the development of effective treatment options. -
Antimicrobial Agent
Mafenide Acetate is a potent sulfonamide antimicrobial agent primarily targeting bacterial infections. It exhibits significant antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, as well as antifungal activity against filamentous fungi, including Lichtheimia and Aspergillus flavus. This compound is valuable in research applications related to skin grafts on burn wounds, post-traumatic invasive fungal infections, and the treatment of bacterially contaminated wounds. -
Antifungal Agent
10-Undecenoic acid zinc salt is an antifungal agent that targets various fungal pathogens. It demonstrates biological activity by inhibiting Aβ oligomerization, scavenging reactive oxygen species (ROS), and inhibiting μ-calpain activity, contributing to its neuroprotective properties. Additionally, this compound has anticancer effects against multiple tumor types and effectively inhibits biofilm formation by C. albicans as well as infections from MRSA. Furthermore, 10-Undecenoic acid zinc salt disrupts quorum sensing signals in Bacillus subtilis and Pseudomonas aeruginosa, highlighting its broad-spectrum antimicrobial potential. -
Antifungal/Exosome Inhibitor
Neticonazole hydrochloride is an imidazole derivative that acts as a potent antifungal agent through the inhibition of fungal sterol synthesis. In addition to its antifungal properties, it has shown promising anti-cancer effects, primarily through the modulation of exosome release and related pathways. This compound is suitable for research applications aimed at exploring antifungal therapies and investigating potential anti-cancer mechanisms. -
Fungal Inhibitor
Piroctone olamine is a pyridine derivative that acts as a potent fungal inhibitor by disrupting fungal cell membrane integrity. It exhibits fungicidal activity effective against a variety of dermatophytes and yeast, making it valuable for research in antifungal treatment and dermatological applications. Its mechanism of action supports investigations into fungal pathogenesis and the development of antifungal therapies. -
Antifungal Agent
Econazole is an orally active imidazole antifungal agent that primarily targets the cytochrome P-450 enzyme system. It demonstrates significant antifungal activity against various fungi and some Gram-positive bacteria, while lacking efficacy against Gram-negative bacteria. Additionally, econazole is known to inhibit prostaglandin synthesis and may induce hepatotoxicity, making it valuable in the study of antifungal resistance and the mechanisms of liver injury. -
Fungal Inhibitor
Dehydroacetic acid sodium is a pyrone derivative known for its fungicidal properties. It exhibits antibacterial and antifungal activity, making it valuable for applications in microbial control in various settings. Additionally, dehydroacetic acid demonstrates phytotoxic effects, indicating its potential use in agricultural research. -
Anti-Fungal Agent
Enactin Va is an anti-fungal agent derived from the strain of Streptomyces roseoviridis. It exhibits mild antifungal activity, making it suitable for research applications aimed at exploring antifungal properties and mechanisms of action. This compound can be utilized in studies focused on the development of novel antifungal therapies and the assessment of fungal resistance. -
Antifungal Agent
Cryptosporiopsin A is a polyketide that acts as an antifungal agent, demonstrating significant motility inhibitory and lytic activities against the zoospores of Plasmopara viticola, the pathogen responsible for grapevine downy mildew. This compound is valuable for research applications focused on understanding fungal biology and developing innovative antifungal strategies. -
Antimicrobial Agent
Octacosamicin B is an antimicrobial agent that exhibits activity against yeast and filamentous fungi. While its efficacy against bacteria is limited, it serves as a valuable tool in the study of antifungal mechanisms and the development of new antifungal therapies. This compound is useful in various research applications focused on microbial resistance and antifungal activity.
