Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
Corypalmine is a naturally occurring alkaloid derived from Stephania cepharantha, known for its antifungal properties. It primarily targets fungal cells, inhibiting their growth and proliferation. This compound is useful in various research applications focused on fungal infections and the development of antifungal therapies. -
Deuterated Posaconazole
Posaconazole-d4 is a deuterated derivative of Posaconazole, a second-generation triazole antifungal agent. This compound exhibits broad-spectrum antifungal activity, inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes. Posaconazole-d4 is primarily utilized in pharmacokinetic studies and metabolic research to trace and quantify the metabolic pathways of Posaconazole in various biological systems. -
Fungicide Agent
Cyprodinil is a broad-spectrum anilinopyrimidine fungicide with a primary mechanism of inhibiting fungal methionine biosynthesis. It effectively protects fruits and vegetables from various plant-pathogenic fungi and also exhibits both anti-androgenic and androgenic activities. Cyprodinil is applicable in research focused on fungal resistance mechanisms and agricultural protection strategies. -
Antifungal Agent
6-Hydroxycoumarin functions primarily as an antifungal agent, demonstrating significant antifungal properties. This compound also exhibits anti-inflammatory, antioxidant, vasodilatory, anti-bacterial, anti-amoebic, and antitumor activities. It is valuable for research in various fields, including pharmacology and medicinal chemistry, particularly for the exploration of natural product derivatives in therapeutic applications. -
Fungal Inhibitor
Multifungin (Bromochlorosalicylanilide) is a potent antifungal agent that inhibits fungal growth, making it particularly effective in treating oral candidiasis. This compound disrupts the formation and accumulation of Zearalenone and is effective in reducing fungal populations in stored-crushed corn. Multifungin is valuable for various research applications aimed at understanding fungal infections and developing antifungal therapies. -
CaFBA Inhibitor
FBA-IN-1 is a first-in-class, covalent allosteric inhibitor of fructose-1,6-bisphosphate aldolase (CaFBA) derived from Candida albicans. This compound effectively inhibits the growth of azole-resistant strains with a minimum inhibitory concentration (MIC80) of 1 µg/mL. Its unique mechanism of action positions FBA-IN-1 as a valuable tool in antifungal research, particularly for studying drug-resistant pathogens and exploring new therapeutic avenues. -
Antifungal Agent
Lanoconazole is a potent imidazole antifungal agent that demonstrates significant activity against a wide range of fungi both in vitro and in vivo. Its primary mechanism involves the inhibition of sterol 14-alpha demethylase, leading to disrupted ergosterol biosynthesis within fungal cell membranes. Lanoconazole is valuable for research applications focusing on dermatophytosis and onychomycosis, providing insights into fungal infections and potential therapeutic interventions. -
Antifungal Agent
Prothioconazole is a triazolinthione fungicide that primarily acts as a CYP51 inhibitor. This compound exhibits potent antifungal activity, making it effective against a variety of fungal pathogens. It is widely utilized in agricultural research and plant pathology to study fungal resistance and to develop innovative fungicidal strategies. -
Fungicide
Diniconazole is a systemic fungicide that acts by inhibiting the biosynthesis of sterols, thereby disrupting fungal cell membrane formation. It demonstrates potent fungicidal activity against various plant pathogens, including Botrytis cinerea, Sordaria fumigata, Fusarium graminearum, Sclerotium cepivororum, and Bipolaris sorokiniana, with IC50 values ranging from 0.001 to 0.06 mg/L. Diniconazole is utilized in research aimed at managing plant fungal diseases and regulating plant growth, making it valuable for agricultural and botanical studies. -
Chitin Deacetylase Inhibitor
Benzohydroxamic acid (BHA) is a potent inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal activity. With Ki values of 8.31 μM against CDA from Verticillium dahliae and 9.83 μM against CDA from Puccinia striiformis f. sp. tritici, BHA effectively restores defense responses in infected host plants by upregulating defense-related gene expression. Its application is crucial in research focused on mitigating agricultural fungal diseases, including those caused by Verticillium dahliae and Puccinia striiformis, contributing to the control of cotton wilt and wheat stripe rust. -
Antifungal Agent/HIV-1 Inhibitor
Amphotericin B methyl ester is a methyl ester derivative of the polyene antibiotic Amphotericin B, targeting cell membranes through cholesterol binding. Exhibiting potent antifungal activity, it effectively disrupts the structural integrity of fungal cells. Additionally, Amphotericin B methyl ester has demonstrated the ability to inhibit HIV-1 particle production and replication, making it valuable for research in both antifungal therapies and HIV-1 studies. -
Fungal Gwt1 Enzyme Inhibitor
APX2039 is a potent inhibitor of the fungal Gwt1 enzyme, functioning through its ability to disrupt glycosylphosphatidyl inositol (GPI) anchoring of cell wall mannoproteins. This compound demonstrates significant anticryptococcal activity against Cryptococcus neoformans and Cryptococcus gattii. APX2039 is applicable in research focused on Cryptococcal meningitis (CM) and offers valuable insights into fungal pathogenesis and treatment strategies. -
Fungal Inhibitor
Triflumizole is an imidazole fungicide that functions by inhibiting ergosterol biosynthesis, which is essential for fungal cell membrane integrity. This compound is effective against a range of fungal pathogens, particularly in the management of powdery mildew and scabs on various fruits and crops. It serves as a valuable tool in agricultural research and crop protection strategies. -
Fungal Inhibitor
Viridicatol is a quinolinone alkaloid derived from the fermentation of the endophytic fungus Penicillium sp. R22 in Nerium indicum. This compound exhibits significant antifungal activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 15.6 μg/mL. Viridicatol is suitable for research applications focused on fungal inhibition and antimicrobial activity studies. -
Antifungal Agent
Sulcatone (6-Methyl-5-hepten-2-one) acts primarily as an antifungal agent, exhibiting effective inhibitory properties against various fungal species. This plant-derived volatile organic compound also demonstrates insecticidal activity and has potential applications in studies related to insect pheromones and endogenous metabolites. Additionally, alterations in Sulcatone levels may serve as a complementary diagnostic marker for ulcerative colitis, highlighting its relevance in both pharmacological and research settings. -
Antifungal Agent
Fenhexamid is an antifungal agent that acts as a sterol biosynthesis inhibitor. It exhibits potent fungicidal activity against the plant pathogenic fungus Botryotinia fuckeliana, commonly known as Botrytis cinerea. This compound is widely utilized in agricultural research to control fungal diseases in various crops, providing valuable insights into plant-fungal interactions and crop protection strategies. -
Anti-fungal Agent
trans-Nerolidol serves as an anti-fungal agent with additional properties that enhance chemotherapeutic efficacy. It improves the anti-proliferative effects of Doxorubicin (DOX) against intestinal and breast cancer cells in vitro by increasing DOX accumulation within these cells. Additionally, trans-Nerolidol has been shown to activate apoptosis in vivo, making it a valuable compound for cancer research and therapeutic applications. -
Anthelmintic
Broxaldine is an anthelmintic agent that exhibits activity against Clostridium difficile with a minimum inhibitory concentration (MIC) of 4 µM. In addition to its primary use, Broxaldine demonstrates antifungal properties, making it a valuable compound for research in protozoal and fungal infections. Its broad-spectrum efficacy positions it as a useful tool for studying parasitic diseases and developing novel therapeutic strategies. -
Antifungal Agent
Chlormidazole hydrochloride is an antifungal agent that demonstrates inhibitory activity against a range of fungi and select gram-positive cocci. This compound is particularly effective in treating fungal and bacterial infections affecting the nails and skin, including conditions such as interdigital and periungual mycoses. It is a valuable reagent for research applications focused on antifungal therapies and the study of related infections. -
Fungicide
5-Bromo-3-pyridinol acts as a potential fungicide through its inhibitory effects on fungal growth. This compound serves as a valuable intermediate in chemical and pharmaceutical research, enabling the exploration of its biological activities. Additionally, chlorinated derivatives of 5-Bromo-3-pyridinol have demonstrated promise in the development of effective antifungal agents. -
eEF2 Inhibitor
Sordarin sodium is an inhibitor of eEF2, targeting the diphthamide modification essential for its function. By obstructing the binding of eEF2 to the ribosome complex, Sordarin sodium effectively inhibits protein synthesis. Additionally, Sordarin sodium exhibits antifungal activity, making it valuable for research in the fields of microbiology and antifungal drug development. -
Fungal Inhibitor
Cyproconazole is a triazole fungicide that primarily targets fungal pathogens, offering effective protection for crops, fruits, and vegetables. Its biological activity includes the induction of hepatocellular adenomas and carcinomas in CD-1 mice, while demonstrating low toxicity to zebrafish embryos and impacting their locomotor activity. This compound is applicable in agricultural research and studies focused on toxicology and environmental effects of fungicides. -
Antifungal Agent
Ferron (8-Hydroxy-7-iodo-5-quinolinesulfonic acid) acts as an antifungal agent by disrupting fungal cell wall synthesis, leading to cell lysis. It exhibits significant antiseptic properties, making it effective in preventing and treating bacterial irritations and inflammations of the skin and mucosal surfaces. This compound is primarily used in research applications related to infection control and the study of antifungal mechanisms. -
Fungicide
Iprodione is a diformimide fungicide that exerts its effects by generating reactive oxygen species (ROS), leading to oxidative damage in fungal cells. This compound is widely utilized in agricultural research for its efficacy in controlling a variety of fungal pathogens. Additionally, Iprodione has been identified as an antiandrogen agent, demonstrating the ability to impede adolescent development and adversely affect sexual behavior and reproductive capabilities in rat models. -
Antifungal Agent
Hydroxy Itraconazole is the active metabolite of the triazole antifungal agent Itraconazole. It exhibits antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This compound is utilized in research applications to study antifungal mechanisms and evaluate the efficacy of antifungal therapies. Hydroxy Itraconazole is particularly relevant in the context of fungal infections and their treatment. -
Fungal Inhibitor
Methyl p-coumarate is an esterified derivative of p-Coumaric acid, functioning primarily as a fungal inhibitor. It exhibits significant inhibition of melanin production in B16 mouse melanoma cells, indicating potential roles in cancer research. Additionally, Methyl p-coumarate demonstrates potent in vitro activity against various pathogens, including Alternaria alternata, making it a valuable reagent for studies in antifungal activity and therapeutic applications. -
Aldolase Inhibitor
Phosphoglycolohydroxamic acid is a potent inhibitor of aldolase and triose-phosphate isomerase, demonstrating significant potential in disrupting metabolic pathways. This compound is primarily utilized in research related to antibacterial and antifungal mechanisms, allowing for the exploration of novel therapeutic strategies against microbial infections. Its ability to inhibit key enzymes positions it as a valuable tool in biochemical studies. -
Antifungal Agent
Ledol ((+)-Ledol) is an antifungal agent derived from the volatile oil components of Rhododendron tomentosum. This compound exhibits significant antifungal properties, making it a valuable tool in research focused on fungal infections. Additionally, Ledol demonstrates expectorant and antitussive effects, which may aid in respiratory studies. Caution should be noted regarding potential adverse reactions, including dizziness, nausea, and vomiting. -
Antifungal Agent
o-Vanillin is a naturally occurring compound primarily known for its antifungal properties. It effectively inhibits the mycelial growth of fungi by compromising the integrity of their cell walls and membranes. Additionally, o-Vanillin has been shown to inhibit NF-κB activation induced by Doxorubicin and 4-hydroperoxycyclophosphamide, making it a valuable reagent for research applications in fungal pathogenesis and cancer studies. -
Growth Regulator
Phenoxyacetic acid acts as an auxin-type growth regulator, modulating plant growth and development. This compound is instrumental in agricultural research, showcasing insecticidal, herbicidal, and antifungal activities through its derivatives. Its diverse biological properties make it a valuable tool for studying plant physiology and pest management strategies. -
Fungal Melanization Inhibitor
Coniferin is a glucoside derivative of coniferyl alcohol that functions as a fungal melanization inhibitor. It effectively disrupts the melanin biosynthesis pathway in fungi, making it useful for studies of fungal growth and pathogenicity. Additionally, Coniferin has been shown to inhibit the release of inflammatory mediators such as Prostaglandin E2 and Thromboxane B2, highlighting its potential in research focused on cellular signaling and inflammation. -
Cytochrome bc1 Inhibitor
Inz-5 is a selective inhibitor of the mitochondrial cytochrome bc1 complex, targeting fungal pathogens. This compound effectively impairs fungal virulence and may prevent the development of resistance to antifungal agents. Its unique mechanism of action makes it a valuable tool for research in mycology and antifungal drug development. -
Aromatic Aldehyde
Octanal is an aromatic aldehyde known for its antioxidant and antibacterial properties. It exhibits antifungal activity against G. citri-aurantii, potentially through the disruption of cell membrane integrity, leading to cellular component leakage. Furthermore, Octanal demonstrates cytotoxic effects on HeLa cells, with an IC50 value of 3.5 μg/mL, making it a valuable compound for research in cell biology and pharmacology. -
Fungal Inhibitor
Enfumafungin is a triterpene glycoside that acts as a potent fungal inhibitor by targeting (1,3)-beta-D-glucan synthase in the fungal cell wall. This compound exhibits selective antifungal activity against yeasts and filamentous fungi, excluding Cryptococcus, and is not active against Bacillus subtilis. Enfumafungin is valuable for research applications focused on fungal pathogenesis and the development of antifungal therapeutics. -
Organic Ligand
2,5-Dihydroxy-1,4-benzoquinone (DHBQ) is a redox-active organic ligand known for its antibacterial properties. This compound is derived from fungal metabolites and plays a significant role in enhancing the performance of Li+-ion battery cathodes through a two-electron redox process when incorporated into Fe (dhbq) metal-organic frameworks. Additionally, 2,5-Dihydroxy-1,4-benzoquinone is utilized in the construction of conductive metal-organic frameworks, making it valuable for research in energy storage and related applications. -
Antifungal Agent
Datiscetin is a natural antifungal agent derived from the cultivar "Roland." It exhibits potent fungitoxic activity against Fusarium oxysporum f. sp. dianthi, making it a valuable compound for research into fungal infections and plant pathology. This compound is of particular interest for studies aimed at developing new antifungal strategies and understanding fungal resistance mechanisms. -
Episterol Derivative
5-Dehydroepisterol is an episterol derivative involved in steroid biosynthesis. It is produced by the action of C-5 sterol desaturase and can be further converted into 24-methylenecholesterol through the activity of 7-dehydrocholesterol reductase. This compound exhibits notable antifungal properties, making it valuable for research applications focused on steroidogenesis and antifungal mechanisms. -
Antifungal Agent
Poacic Acid is a plant-derived stilbenoid that serves as a potent antifungal agent. It disrupts the production and assembly of β-1,3-glucan within the cell walls of fungi by localizing to the yeast cell wall. Poacic Acid demonstrates fungicidal activity against Saccharomyces cerevisiae and Candida albicans mutants with compromised plasma membranes, making it valuable for antifungal research and therapeutic studies. -
Stress Enhancer
Galactinol is a disaccharide carbohydrate that functions as a galactosyl donor, primarily acting as an osmoprotectant. It enhances plant disease resistance against fungal and bacterial pathogens while improving tolerance to abiotic stresses such as drought, high salinity, low temperatures, and oxidative damage. Additionally, Galactinol scavenges hydroxyl radicals and plays a role in root colonization-induced systemic resistance. Its positive correlation with seed longevity positions Galactinol as a potential biomarker for seed vigor, making it valuable in researching various plant diseases, including fungal leaf spot and bacterial angular leaf spot. -
SDH Inhibitor
SDH-IN-1 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 4.53 μM. This compound demonstrates significant antifungal properties, particularly effective against S. sclerotiorum with an EC50 of 0.14 mg/L. SDH-IN-1 is a valuable tool for researchers studying fungal pathogenesis and metabolism, providing insights into SDH's role in cellular respiration and therapeutic strategies against fungal infections. -
Quorum Sensing Molecule
(E,E)-Farnesol is a quorum-sensing molecule that plays a crucial role in regulating the growth and behavior of Candida species. It effectively inhibits the growth, metabolism, and biofilm formation of various Candida strains while also impacting their morphology and invasiveness. This compound is valuable for research focused on fungal pathogenesis and the development of antifungal strategies. -
Broad-spectrum foliar fungicide
Chlorothalonil is a broad-spectrum foliar fungicide that primarily targets fungal pathogens in agricultural settings. This compound is effective in controlling a wide range of fungal diseases affecting vegetable and crop leaves, contributing to improved plant health and yield. Additionally, chlorothalonil has been shown to interfere with spermatogenesis and can induce intestinal epithelial barrier dysfunction, as well as fetal toxicity, making it a subject of study in developmental and reproductive biology. -
Antifungal Agent
3,5-Di-tert-butylphenol is a volatile organic compound that serves as an antifungal agent by inhibiting biofilm formation. It effectively induces the accumulation of reactive oxygen species (ROS) in Candida albicans cells, contributing to its antifungal properties. Additionally, 3,5-Di-tert-butylphenol exhibits antibacterial activities, making it a valuable tool for research in microbial pathogenesis and the development of anti-infective strategies. -
Fungal Inhibitor
Thiophanate-Methyl is a systemic fungicide that targets fungal pathogens by inhibiting mycelial growth and spore germination. This compound exhibits broad-spectrum activity against a variety of fungi, making it useful in agricultural applications for disease management in crops. Its mechanism of action involves the disruption of cellular processes within the target fungi, providing an effective solution for controlling fungal infections in plants. -
Fungicide
Metalaxyl is a systemic fungicide that targets protein synthesis in fungi, effectively disrupting cellular functions. It demonstrates significant activity against downy mildews and soil-borne pathogens, particularly those caused by Phytophthora and Pythium species. This compound is widely utilized in agricultural research for the management of fungal diseases, providing essential insights into plant disease resistance and control strategies. -
Lysosomotropic Detergent
1-Dodecylimidazole is a lysosomotropic detergent that induces cytotoxic effects through acid-dependent accumulation in lysosomes, leading to membrane disruption and the release of cysteine proteases into the cytoplasm. This compound exhibits hypocholesterolemic properties and demonstrates broad-spectrum antifungal activity. It is valuable for research applications involving cell death mechanisms, lysosomal function studies, and antifungal investigations. -
Fungal Inhibitor
Deoxylapachol is a significant cytotoxic compound derived from the New Zealand brown alga Landsburgia quercifolia, primarily acting as a fungal inhibitor. It exhibits notable antifungal properties, making it a valuable agent in the study of fungal infections. Additionally, deoxylapachol demonstrates anti-cancer activity, positioning it as a candidate for research applications in oncology and pathogen interaction studies. -
Fungal CYP51 Inhibitor
VT-1598 is an orally active and selective inhibitor of fungal cytochrome P450 51 (CYP51). It exhibits potent antifungal activity against Candida auris, making it a valuable tool for research into fungal infections. Additionally, VT-1598 contains an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) for click chemistry applications, facilitating the study of various biological interactions. -
Fungal
Aegeline is a natural alkaloid that targets fungal pathways by mimicking the yeast SNARE protein Sec22p to inhibit α-synuclein and Bax toxicity in yeast models. This compound effectively restores growth in yeast cells impaired by these toxic proteins. Additionally, Aegeline exhibits antioxidant properties, making it a valuable reagent for studying cellular stress responses and neurodegenerative mechanisms in fungal systems. -
Fungicide
Fenpropimorph is a fungicide that targets the sterol biosynthesis pathway by inhibiting δ8-δ7-sterol isomerase in yeast at low concentrations, while δ14-sterol reductase is inhibited at higher concentrations. This action disrupts ergosterol production, an essential component of fungal cell membranes. Additionally, Fenpropimorph affects sterol synthesis in select plant species and mammalian cells, making it valuable for both agricultural and biomedical research applications.
