Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Fungal Agent
Azoxybacilin is an anti-fungal agent that primarily inhibits sulfur fixation in methionine biosynthesis. This compound exhibits significant activity against filamentous fungi, making it useful for research applications in fungal biochemistry and pathogenesis studies. Its mechanism of action may provide insights into sulfur metabolism and antifungal resistance mechanisms. -
Antifungal Agent
Irtemazole is an orally active antifungal agent that primarily targets fungal pathogens. It exhibits a uricosuric effect, enhancing uric acid excretion. This compound is utilized in research addressing fungal infections such as blastomycosis, histoplasmosis, and aspergillosis, making it a valuable tool in the study of antifungal therapies. -
Antifungal Agent
δ-Dodecalactone is a lactone compound with significant antifungal properties. It demonstrates potent activity against a range of molds, including Aspergillus flavus, A. fumigatus, A. petrakii, A. ochraceus, A. nidulans, and Penicillium roqueforti. Due to its strong antifungal effects, δ-Dodecalactone is valuable in research applications focused on mycology and the development of antimicrobial agents. Additionally, it serves as a flavoring compound in various culinary applications. -
Antifungal Agent
Etheroleic acid is an antifungal agent that exhibits potent activity against the powdery mildew fungus B. graminis in barley seedlings. As a metabolite of linolenic acid, it may play a crucial role in plant defense mechanisms and can be utilized in agricultural research to explore its effectiveness against fungal pathogens. -
Antifungal Antibiotic
Dactylfungin B is an antifungal antibiotic with potent activity against Candida pseudotropicalis and various other fungal species, demonstrating a minimum inhibitory concentration (MIC) of less than 10 μg/mL. This compound is valuable for research applications focused on fungal infections, resistance mechanisms, and the development of new antifungal therapies. Its efficacy positions it as a promising candidate for further studies in mycology and pharmacology. -
Antimicrobial Agent
Concanamycin G is a specific inhibitor of the V-type ATPase, with a reported Ki of 0.02 nM. It exhibits a range of biological activities, including antifungal, antiviral, immunosuppressive, and cytotoxic effects. This compound is a valuable tool in biochemical research, particularly in studies involving cellular energy regulation and membrane transport processes. -
Antimicrobial Agent
Neocopiamycin A is an antimicrobial agent that demonstrates broad-spectrum activity against Gram-positive bacteria, yeast, and filamentous fungi. Its robust mechanism of action makes it a valuable tool in the study of antimicrobial resistance and the development of novel antifungal treatments. This compound is suitable for research applications focused on microbiological assays and the exploration of microbial susceptibility. -
Agriculture Fungicide
Azaconazole is a systemic fungicide that targets fungal cytochrome P450 enzymes, inhibiting ergosterol biosynthesis. It exhibits potent antifungal activity against powdery mildew and bean rust, making it effective in agricultural applications. Azaconazole is utilized to protect a variety of crops, ensuring healthier yields and improved plant health. -
Antifungal Agent
Bupirimate is a systemic fungicide that acts as an inhibitor of adenosine deaminase (ADA). It exhibits significant antifungal activity, particularly against powdery mildew, making it valuable in agricultural applications. Bupirimate is utilized in the cultivation of fruit trees, vegetables, and ornamental plants to effectively manage and control fungal infections, thereby enhancing crop yield and health. -
CDA Inhibitor
CDA-IN-4 is a chitin deacetylase (CDA) inhibitor. It demonstrates a protective effect of 61.2% against rice blast disease at a concentration of 100 μg/mL. This compound is pertinent for research applications targeting fungal infections in plants and exploring mechanisms of disease resistance. -
Antifungal Antibiotic
Pradimicin B is an antifungal antibiotic that targets fungal cell membranes. It exhibits significant antifungal and yeast activity, making it valuable for research into fungal infections and potential therapeutic applications. This compound may facilitate studies on the mechanisms of antifungal resistance and the development of new antifungal agents. -
Anti-Fungal Agent
Acrylamidine is an anti-fungal agent that exhibits activity against mold and yeast. This compound can be utilized in research applications aimed at understanding fungal resistance mechanisms and developing new therapeutic strategies for fungal infections. Its weak activity profile makes it a candidate for further modification and study in the pursuit of more potent anti-fungal agents. -
Fungal Inhibitor
Methoxyanigorufone is a fungal inhibitor derived from Musa acuminata var. "Yangambi km 5." This compound exhibits significant antifungal activity, demonstrating effectiveness against a range of pathogenic fungi. It is particularly useful in studies exploring fungal resistance mechanisms and the development of antifungal agents in research applications. -
Anti-Fungal Agent
Enactin Ia is a secondary metabolite derived from the strain of Streptomyces roseoviridis, functioning as an anti-fungal agent. This compound exhibits limited antifungal activity and can be utilized in research related to fungal pathogenesis and the efficacy of antifungal agents. Its characterization contributes to the understanding of microbial metabolites and their potential applications in combating fungal infections. -
BcSDH Inhibitor
SDH-IN-45 is an inhibitor of succinate dehydrogenase (BcSDH) that targets Botrytis cinerea, exhibiting an IC50 of 5.97 μg/mL. This compound impedes fungal energy metabolism through a distinct binding mode, leading to morphological disruptions, including structural collapse and shrinkage of mycelial forms. SDH-IN-45 demonstrates potent in vitro fungicidal activity against Botrytis cinerea, making it a valuable reagent for research focused on cucumber gray mold and related phytopathological studies. -
TMV Inhibitor
TMV-IN-15 is a potent inhibitor of Tobacco Mosaic Virus (TMV) by targeting the TMV coat protein (TMV-CP). This compound effectively suppresses viral particle assembly, leading to significant aggregation and structural fusion of viral components. TMV-IN-15 also demonstrates inhibitory activity against important fungal pathogens such as Physalospora piricola and Rhizoctonia cerealis. This reagent is valuable for research applications in antiviral and antifungal pesticide development. -
Succinate Dehydrogenase Inhibitor
SDH-IN-38 is a potent inhibitor of succinate dehydrogenase, primarily targeting mycelial respiration. Demonstrating significant antifungal activity, SDH-IN-38 exhibits an EC50 value of 0.009 μg/mL against R. solani mycelia, effectively inhibiting mycelial growth. Additionally, this compound induces cellular senescence and reduces mitochondrial membrane potential in fungal cells, making it a valuable tool for research in fungal biology and disease management. -
Anti-Fungal Agent
9-Hydroxyoudemansin A is an antifungal agent that exhibits significant activity against ochre-like yeast, with a minimum inhibitory concentration (MIC) of 12.5 µg/mL. This compound demonstrates resistance to various fungi, including Candida albicans, Crimson Yeast, Penicillium, and Streptomyces, all with MICs greater than 50 µg/mL. It is primarily utilized in research focused on fungal infections and exploring novel antifungal therapies. -
Antifungal Agent
Piperanine is an antifungal agent known for its inhibitory activity against the fungus Cladosporium cladosporioides. Isolated from the fruits of Piper retrofractum, piperanine demonstrates potential in combating fungal infections and can be utilized in research focused on antifungal drug development and therapeutic applications. Its efficacy against specific fungal strains makes it a valuable compound for studies in mycology and agricultural biology. -
Anti-Fungal Agent
Chondramide C functions as an anti-fungal agent, demonstrating significant activity against Candida species, Henson yeast, lipid yeast, and other fungal forms. Its selective spectrum of action shows no efficacy against Gram-positive or Gram-negative bacteria, making it a valuable tool in fungal research and potential therapeutic applications. -
Antifungal Agent
A25822B is an antifungal agent that exhibits a minimal inhibitory concentration (MIC) of 1 μM against Ascosphaera apis. It induces conformational changes in mitochondrial structures while disrupting the integrity of spore membranes. This compound is suitable for research focused on bee chalk disease and related fungal infections. -
Antifungal Agent
Sarisan (Asaricin) is a phenolic compound primarily recognized for its antifungal properties. Extracted from the stem bark of Ocotea opifera Mart., Sarisan exhibits significant activity against various fungal pathogens. This compound is valuable in research applications focused on developing antifungal treatments and investigating the ecological roles of plant-derived antifungals. -
Antimicrobial Agent
Octacosamicin A is an antimicrobial agent that exhibits activity against yeast and filamentous fungi, with moderate efficacy against bacteria. This compound is valuable in studies investigating antifungal mechanisms and the development of novel antimicrobial therapies. Its unique properties make it a potential lead for further research in the field of microbiology. -
Anti-Fungal Agent
6-O-Demethyl-5-deoxyfusarubin is an anti-fungal agent that targets fungal cell growth and proliferation mechanisms. This compound exhibits significant activity against various fungal strains and mycoplasma, making it a valuable tool in anti-fungal research and the development of effective therapeutic strategies. Its efficacy in inhibiting fungal infections highlights its potential applications in microbiology and pharmacology studies. -
Steroidal Sapogenin
Schidigera-genin B is a steroidal sapogenin derived from Yucca glauca. It demonstrates weak antifungal activity and can be utilized in research applications focused on assessing natural compounds with potential therapeutic effects. This compound may serve as a valuable tool in studying sapogenins and their biological roles. -
Anti-Fungal Agent
Phoslactomycin D is an anti-fungal agent that exhibits potent activity against various fungal species. While it demonstrates limited efficacy against Gram-positive bacteria, its primary application lies in targeting fungal infections. This compound is particularly valuable for researchers exploring antifungal mechanisms or developing new treatments for fungal diseases. -
Antifungal Agent
Posaconazole hydrate is a broad-spectrum antifungal agent classified as a second-generation triazole derivative. It exerts its activity by inhibiting the enzyme lanosterol 14α-demethylase, crucial for ergosterol synthesis in fungal cell membranes. This compound is particularly effective against various fungal pathogens and is utilized in both in vitro and in vivo studies to explore its efficacy in treating invasive fungal infections. -
Anti-Fungal Agent
Haliangicin D is an anti-fungal agent with potent activity against filamentous fungi and oomycetes. It does not exhibit antibacterial properties. This compound is valuable in research applications exploring fungal infections and the mechanisms of fungal pathogenicity. -
Diffusion Signaling Factor
trans-11-Methyl-2-dodecenic acid is an isomer of cis-11-Methyl-2-dodecenoic acid and functions as a diffusion signaling factor (DSF) in microbial and fungal communication. It plays a crucial role in quorum sensing (QS), facilitating extracellular interactions among microbial populations. This compound is significant for studies on microbial ecology and can be utilized to investigate signaling mechanisms in various biological systems. -
Calcineurin Inhibitor
JH-FK-08 is a potent inhibitor of the serine/threonine-specific phosphatase calcineurin. It demonstrates significant antifungal activity against Cryptococcus neoformans, with a MIC80 of 0.8 µg/mL, and displays immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 also shows efficacy in mouse models for anti-infectious applications, making it valuable for research in immunology and infectious disease. -
Antifungal Agent
Ampelopsin A is an antifungal agent derived from the canes of Vitis vinifera. This compound exhibits significant antifungal activity, making it a valuable tool in the study of fungal infections. Additionally, Ampelopsin A demonstrates neuroprotective effects, which may be relevant for research focused on neurodegenerative diseases and cellular protection mechanisms. -
Anthraquinone Derivative
Neobulgarone D is an anthraquinone derivative derived from Neobulgaria pura HA A07-97, a member of the ascomycetes class. This compound effectively inhibits appressorium formation in the fungal pathogen Magnaporthe grisea, making it valuable in studies related to plant pathology. Additionally, Neobulgarone D exhibits low cytotoxicity and lacks antifungal, antibacterial, or phytotoxic effects, positioning it as a suitable reagent for research applications focused on fungal biology and pathogen interactions. -
Anti-Fungal Agent
Maniwamycin B is an anti-fungal agent that targets fungal cell wall synthesis. It exhibits potent inhibitory activity against a variety of pathogenic fungi, making it valuable for research in fungal infections and resistance mechanisms. This compound can be utilized in studies aimed at understanding fungal biology and developing new antifungal therapies. -
Antifungal Compound
(±)-Dunnione is an antifungal compound that operates through the mechanism of redox cycling. This compound exhibits broad-spectrum antifungal activity, making it a valuable tool for studying fungal pathogens. Its application in research encompasses the investigation of antifungal mechanisms and potential therapeutic interventions against various fungal infections. -
Antimicrobial Agent
Darlucin A is an antimicrobial agent that exhibits potent antibacterial and antifungal activity. This compound has shown promising effects against a range of microbial pathogens while demonstrating low cytotoxicity to human cells. Darlucin A is valuable for research applications focused on developing new antimicrobial therapies and exploring mechanisms of resistance in bacteria and fungi. -
Anti-Fungal Agent
Fosfazinomycin B is an anti-fungal agent that exhibits inhibitory activity against plant pathogenic fungi, particularly Xanthomonas oryzae. It demonstrates potential applications in agricultural research for the development of disease-resistant crops. This compound serves as a valuable tool for studies focused on plant-fungal interactions and the exploration of novel antifungal strategies. -
Antimicrobial Agent
Aspergillus niger-IN-1 is a thiazolidine-2,4-dione derivative functioning as an antimicrobial agent. It demonstrates significant antimicrobial activity against a range of bacterial and fungal strains, including Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, Salmonella typhi, Candida albicans, and Aspergillus niger, with minimum inhibitory concentration (MIC) values ranging from 5.65 to 11.3 μM/mL. This compound is suitable for research applications in microbiology and therapeutic development targeting resistant infections. -
Fungal Inhibitor
Bromomonilicin is a selective inhibitor of fungal cell membranes. It exerts its antifungal activity by disrupting the integrity of fungal cell membranes, making it a valuable tool for studying plant pathogenic fungal infections, such as those caused by Monilinia fructicola leading to brown rot, as well as superficial mycoses, including dermatophyte infections. This compound is essential for research aimed at understanding and combating fungal diseases in both agricultural and clinical settings. -
Antimicrobial Agent
Gageotetrin B is an antimicrobial agent with significant activity against a range of microorganisms. Demonstrating higher potency towards fungal species, Gageotetrin B exhibits minimum inhibitory concentrations (MIC) ranging from 0.01 to 0.04 μM. This compound is valuable for research in microbiology and antifungal drug development. -
Anti-Fungal Agent
Chandrananimycin A is an anti-fungal agent that demonstrates potent activity against various mucor species. In addition, it exhibits anti-tumor effects against several cancer cell lines, including CCL HT29, MFXF 529L, and MACL McF-7. This compound is valuable in research applications focused on fungal infections and cancer biology. -
Squalene Synthase Inhibitor
E5700 is a potent squalene synthase inhibitor, exhibiting an IC50 of 0.49 nM against squalene synthase from Trypanosoma cruzi epimastigotes. This compound demonstrates notable antiparasitic activity, effectively inhibiting the growth of Trypanosoma cruzi and Leishmania amazonensis. Additionally, E5700 impacts the lipid profile and ultrastructure of multi-drug resistant Candida tropicalis strains, making it a valuable tool for research on parasitic infections and antifungal resistance mechanisms. -
Fungal Inhibitor
Butenafine-d4 is a deuterium-labeled analogue of Butenafine, a potent benzylamine antifungal agent. It exerts its antifungal activity by specifically inhibiting ergosterol biosynthesis at the squalene epoxidation step, which disrupts fungal cell membrane integrity. Butenafine displays effectiveness against a range of dermatophyte infections, including tinea pedis, tinea cruris, and tinea versicolor. This reagent is suitable for research applications focused on antifungal mechanisms and the study of fungal pathogens. -
Aminoacyl tRNA Synthetase Inhibitor
Aminoacyl tRNA synthetase-IN-4 is a potent inhibitor of aminoacyl tRNA synthetase, exhibiting an IC50 value of 0.026 μM against Candida albicans prolyl-tRNA synthetase. This compound is valuable for antifungal research, providing insights into the role of aminoacyl tRNA synthetase in fungal biology and potential therapeutic strategies against infections. Its selective inhibition profile makes it an important tool for exploring the mechanisms of antifungal resistance and treatment efficacy. -
SDH Inhibitor
SDH-IN-37 is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 0.0263 μM. Additionally, this compound demonstrates significant antifungal activity against pathogens such as Rhizoctonia solani, Sclerotinia sclerotiorum, and Fusarium graminearum, with EC50 values of 0.0144, 0.882, and 1.99 μg/mL, respectively. SDH-IN-37 is therefore a valuable tool for research applications focused on fungal pathogenesis and metabolic regulation in various organisms. -
Antifungal Agent
Bulnesol is a sesquiterpenoid with antifungal properties, isolated from Salvia dorystaechas. It exhibits inhibitory activity against Fusarium moniliforme, with an EC50 value of 0.6 mg/mL. Bulnesol is suitable for research applications focused on fungal infections and the development of antifungal agents. -
Antifungal Agent
3-Piperidinopropiophenone hydrochloride is a mono Mannich base derived from acetophenone, exhibiting significant antifungal activity. This compound functions as an effective antifungal agent, making it valuable for research in mycology and the development of antifungal therapeutics. Its mechanistic pathways and biological implications are of interest for studies aimed at combating fungal infections. -
Histidine kinase Inhibitor
RWJ-49815 is a potent inhibitor of histidine kinases, exhibiting an IC50 value of 1.6 µM. It effectively inhibits the autophosphorylation activity of kinase A within the KinA-Spo0F two-component signaling system in vitro. This compound demonstrates significant antimicrobial activity against resistant bacterial strains, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus pneumoniae. Additionally, RWJ-49815 shows inhibitory effects on fungal species such as Saccharomyces cerevisiae and Candida albicans, making it a valuable tool for studying kinase-mediated processes and developing antimicrobial strategies. -
Antimicrobial Agent
Linearmycin B is an antimicrobial agent that exhibits potent antibacterial and antifungal properties. It demonstrates significant inhibitory activity against key pathogens, including Bacillus subtilis, Staphylococcus aureus, Candida albicans, and Saccharomyces cerevisiae, with minimum inhibitory concentrations (MIC) of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively. This compound is valuable for research applications focusing on the development of antimicrobial therapies and the study of microbial resistance mechanisms. -
Fungal Inhibitor
Fenpyrazamine is an antifungal agent that primarily targets 3-keto reductase within the ergosterol biosynthesis pathway. It exhibits significant antifungal, preventative, systemic, and lesion-inhibiting properties, providing a prolonged therapeutic effect. Fenpyrazamine is efficacious against pathogens such as gray mold, stem rot, and brown rot, making it a valuable reagent for research focused on fungal infections and plant pathology. -
Antimicrobial Agent
Damavaricin D functions as an antimicrobial agent, exhibiting potent activity against both Gram-positive and Gram-negative bacteria, as well as antifungal properties. This compound is valuable for research applications focused on the development of new antibacterial and antifungal therapies, especially in the context of emerging resistant strains. Its broad-spectrum efficacy makes it a significant candidate for further investigation in microbiological studies.
