Catalog No.
Product Name
Application
Product Information
Citations
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Opioid Receptor Agonist
Hodgkinsine B acts as an opioid receptor agonist, providing notable analgesic effects and demonstrating anti-injurial properties. Additionally, it functions as an NMDA receptor antagonist and possesses antiviral, antibacterial, and antifungal activities. This compound is valuable for research applications focused on pain management, neuroprotection, and antimicrobial studies. -
Fungal Inhibitor
Inz-4 is a selective inhibitor of mitochondrial cytochrome bc1 in fungi, demonstrating an IC50 of 0.026 μM. This compound effectively disrupts mitochondrial respiration in fungal species, making it a valuable tool for studying fungal metabolism and potential therapeutic applications in antifungal research. Its potent activity underscores its utility in investigating the biochemical pathways of fungi and the development of antifungal agents. -
Fungicide
Pterophyllin 2 is a potent fungicide targeting Rhizopus stolonifer, exhibiting a minimum fungicidal concentration (MFC) of 250 μg/mL. Additionally, Pterophyllin 2 demonstrates significant antifungal activity against Botrytis cinerea and Monilinia fructicola. This compound is valuable in agricultural and microbiological research applications focused on controlling fungal pathogens. -
Antifungal Agent
(Rac)-Luliconazole is a broad-spectrum antifungal agent belonging to the imidazole class of compounds. This racemic isomer exhibits potent antifungal activity, making it effective against a variety of fungal pathogens. It is primarily utilized in research applications focused on dermatological infections and antifungal mechanism investigations. -
Antifungal Agent
Micafungin metabolite M1 is an active metabolite of Micafungin that targets fungal cell wall synthesis, exhibiting potent antifungal activity. This compound is particularly effective against deep fungal infections caused by Candida and Aspergillus species, making it valuable for research applications in mycology and antifungal drug development. Its specific mechanism of action enhances its potential in studies assessing the efficacy of antifungal therapies. -
Fungal Inhibitor
Candicidin A3 is a potent antifungal antibiotic that demonstrates significant inhibitory activity against fungal growth. Its unique three-dimensional structure and seven-membered ring configuration enhance its biological efficacy and interaction with fungal targets. This compound presents potential for development as a therapeutic agent in the treatment of fungal infections, making it a valuable tool for researchers studying antifungal mechanisms and developing new treatments for mycotic diseases. -
14α-lanosterol demethylase Inhibitor
Arasertaconazole is a potent inhibitor of 14α-lanosterol demethylase, an enzyme critical in the biosynthesis of sterols in fungi. This compound exhibits significant antifungal and antibacterial activities, making it valuable in studies focused on the treatment of fungal infections and bacterial pathogens. Its inhibition of key enzymatic pathways underscores its research applications in drug development and microbiology. -
Fungal
Sartorypyrone A is a monocyclic terpenoid that targets fungal pathways, isolated from the soil fungus Neosartorya fischeri. It demonstrates in vitro growth inhibitory activity against various cancer cell lines, including MCF-7, NCI-H460, and A375-C5. Its potential anticancer properties make it a valuable compound for cancer research and the investigation of fungal biomolecules. -
Anti-Fungal Agent
Neihumicin is an anti-fungal agent effective against Saccharomyces yeast (ATCC 9763) and Penicillium italicum. This compound exhibits resistance to these specific fungal strains, making it a valuable tool for studying fungal biology and developing antifungal therapies. Neihumicin can aid in understanding the mechanisms of fungal resistance and contribute to the research of potential treatments for fungal infections. -
Antifungal Agent
SCH 39304 is an orally active antifungal agent that demonstrates efficacy against systemic candidiasis, aspergillosis, and cryptococcosis, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg in murine models. Pharmacokinetic evaluations reveal a prolonged half-life and significant systemic exposure in both mice and rats. This compound is applicable in anti-infective research, particularly for studying fungal infections and therapeutic interventions. -
Thiazolidinedione Derivative
Antimicrobial agent-41 is a thiazolidinedione derivative with notable antioxidant activity, demonstrated by an IC50 of 27.66 μg/mL. This compound also exhibits significant antidiabetic effects, with an IC50 of 40.01 μg/mL. Furthermore, Antimicrobial agent-41 shows antimicrobial properties against a range of both bacterial and fungal pathogens, making it a valuable tool for research in microbiology and diabetes-related studies. -
Antimicrobial Agent
Nemotin is an antimicrobial agent that demonstrates activity against Gram-positive bacteria, mycobacteria, and fungi, while exhibiting weaker effects on Gram-negative bacteria. Its broad-spectrum activity makes it suitable for research applications focused on understanding bacterial and fungal resistance mechanisms. This compound serves as a valuable tool in microbiological studies and the development of new antimicrobial therapies. -
Antifungal Antibiotic
Heptaibin is a peptaibol antifungal antibiotic that primarily targets fungal infections. It exhibits significant antimicrobial activity against Gram-positive bacteria, such as Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 8 μg/mL, and demonstrates effectiveness against various fungi including Aspergillus, Candida albicans, and Cryptococcus neoformans, with MIC values ranging from 13 to 32 μg/mL. Additionally, Heptaibin shows moderate activity against Rhabditella pseudoelongata, with an MIC of 50 μg/mL, making it a valuable reagent for research into antifungal treatments. -
Anti-Fungal Agent
Cladosporide B is an anti-fungal agent derived from the strain of Cladosporium sp. IFM 49189. It exhibits potent activity against Aspergillus fumigatus, demonstrating stronger efficacy compared to its analog, Cladosporide A. This compound is valuable for research focused on fungal pathogen inhibition and the development of antifungal therapies. -
Anti-Fungal Agent
Phellinsin is a targeted antifungal agent that selectively inhibits chitin synthase I and II, exhibiting IC50 values of 76 μg/mL and 28 μg/mL, respectively. This compound demonstrates significant antifungal activity against a variety of pathogens, including Colletotrichum lagenarium, Pyricularia oryzae, Aspergillus fumigatus, and Trichophyton mentagrophytes, with minimum inhibitory concentrations (MIC) ranging from 12.5 to 50 μg/mL. Phellinsin serves as a valuable tool for research into fungal biology and the development of antifungal therapies. -
Antifungal Isoflavonoid
Phaseollinisoflavan is an antifungal isoflavonoid known for its role as a phytoalexin. It exhibits potent antifungal activity by inhibiting the growth of various fungal pathogens. This compound is particularly useful in research focused on plant defense mechanisms and the development of antifungal agents in agricultural applications. -
Phytoalexin
Phytoalexine is a natural phytoalexin that exhibits antifungal activity by inhibiting spore germination and mycelial growth in fungi such as Phoma lingam and Phoma wasabiae. This compound is of significant interest in the study of plant defense mechanisms and the development of novel pesticides aimed at managing fungal diseases in crops. Its unique biological properties make it a valuable reagent for research applications related to agricultural biotechnology and plant pathology. -
Antifungal
α-Thujene is a natural compound with notable antifungal properties, primarily targeting fungal pathogens. Extracted from eucalyptus trees, it has demonstrated significant efficacy against Macrophomina phaseolina (85% inhibition) and Botrytis cinerea (84% inhibition), outperforming standard antifungal agents like Nystatin. This compound is of particular interest in research applications focused on developing natural antifungal treatments and studying fungal resistance mechanisms. -
Fungal Inhibitor
Stichloroside B1 is a triterpenoid oligosaccharide that acts as a fungal inhibitor. Isolated from the sea cucumber Stichopus chloronotus, it exhibits significant antifungal activity, making it valuable for research in mycology and the development of antifungal agents. Its unique structure and mechanism of action are of particular interest in studying fungal biology and potential therapeutic applications. -
Cytochrome Bc1 Inhibitor
Inz-1 is a selective inhibitor of mitochondrial cytochrome bc1, exhibiting an IC50 of 8.092 μM in yeast and 45.320 μM in human cells. This compound effectively reverses resistance to Fluconazole and other triazole antifungals in Candida albicans, making it a valuable tool for studying antifungal resistance mechanisms and developing new therapeutic strategies. Researchers can utilize Inz-1 to investigate the role of cytochrome bc1 in fungal pathogenesis and drug resistance. -
Antifungal Peptide
LL-25 is an antifungal peptide that exhibits potent candidacidal activity, making it particularly useful in research focused on fungal infections. This compound is a fragment of LL-37, lacking its immunomodulatory effects, which allows for a more targeted investigation of its antifungal properties. LL-25 is applicable in studies exploring therapeutic strategies against fungal pathogens, providing insights into the development of novel antifungal agents. -
Anti-Fungal Agent
Saricandin is an antifungal agent that primarily targets glucan synthase, exhibiting an ID50 of 242.0 μg/mL. It demonstrates weak antifungal activity, making it a potential candidate for the study of fungal cell wall synthesis and the development of novel antifungal strategies. Research applications include exploring the role of glucan synthase in fungal biology and assessing the efficacy of compound combinations in antifungal treatments. -
Anti-Fungal Agent
Elizabethin is an antifungal agent that exerts its activity by inhibiting fungal growth. This compound is effective against a variety of fungal pathogens, making it a valuable tool for studying antifungal mechanisms and developing new therapeutic strategies. Its applications extend to research in mycology and infectious disease, providing insights into fungal biology and resistance mechanisms. -
Antimicrobial Agent
Enniatin F functions primarily as an antimicrobial agent with notable insecticidal and antifungal properties. This compound inhibits acyl-CoA, cholesterol acyltransferase (ACAT), making it relevant for research applications focused on lipid metabolism and antimicrobial studies. Its diverse biological activities position it as a valuable tool in understanding mechanisms of action against various microbial and pest challenges. -
Anti-Fungal Agent
Mathemycin B is an anti-fungal agent that exhibits significant inhibitory effects on pathogenic fungi. This compound effectively inhibits the growth of Phytophthora infestans JO8 in vitro, with a minimum inhibitory concentration (MIC) of 7.8 μg/mL. Mathemycin B is useful for research applications focused on fungal pathogenesis and therapeutic development against fungal infections. -
Anti-Fungal Agent
Neoenactin B1 is a potent anti-fungal agent that exhibits significant activity against both yeast-like and filamentous fungal strains. Its biological efficacy makes it a valuable tool for research aimed at understanding fungal pathogenesis and developing therapeutic strategies against fungal infections. Neoenactin B1 is suitable for use in studies exploring drug resistance and the mechanisms of fungal growth inhibition. -
Chitin Deacetylase Inhibitor
CDA-IN-5 is a chitin deacetylase inhibitor with a Ki value of 27.5 μM against PstCDA. This compound exhibits antifungal activity, effectively inhibiting the growth of pathogens such as Rhizoctonia solani, Pyricularia oryzae, and Botrytis cinerea. CDA-IN-5 demonstrates moderate efficacy in controlling rice sheath blight, making it a valuable tool for research in agricultural plant pathology and fungal disease management. -
Inhibitor of Uredospore Germination
Methyl 3,4-dimethoxycinnamate is a potent inhibitor of uredospore germination, targeting fungal spores to impede their growth and development. In addition to its antifungal properties, it also suppresses global DNA methylation in Hep3B cells, making it a valuable reagent for research on epigenetic modifications. This compound is suitable for studies in plant pathology and epigenetics, facilitating further investigation into its biological roles and potential applications. -
Antifungal Agent
Chamaejasmenin D is a potent antifungal agent that targets cellular mitosis. It exhibits significant activity against various fungal pathogens by inhibiting their growth and proliferation. This compound is valuable for research applications focused on antifungal drug development and understanding fungal resistance mechanisms. -
Antifungal Antibiotic
Adustin is an antifungal antibiotic that acts as a translation inhibitor. It demonstrates effective inhibition of protein synthesis in a cell-free rabbit reticulocyte lysate system, with an IC50 value of 0.34 μM. This compound is primarily used in research applications focused on investigating fungal infections and the mechanisms of action of antifungal agents. -
SDH Inhibitor
SDH-IN-29 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.0709 μM. This compound demonstrates broad-spectrum antifungal activity, with EC50 values of 0.356 μg/mL for Fusarium graminearum, 0.798 μg/mL for Sclerotinia sclerotiorum, and 0.146 μg/mL for Rhizoctonia solani. SDH-IN-29 also shows moderate to significant protective effects against rice blast, wheat scab, and cucumber powdery mildew, making it a valuable tool for agricultural research and fungal disease management. -
Anti-Fungal Agent
Chondramide A is a potent anti-fungal agent that specifically targets various fungal species, including Candida and several yeast types such as Henson yeast and ball-like yeast. It exhibits significant anti-fungal activity but does not affect Gram-positive or Gram-negative bacteria. This compound is valuable for research applications focused on fungal infections and the mechanisms underlying antifungal resistance. -
Antifungal Antibiotic
Phyllosinol is an antifungal antibiotic that targets fungal cell membranes, disrupting their integrity and leading to cell death. This compound exhibits potent antifungal activity against a variety of pathogenic fungi, making it a valuable tool for studying fungal infections. Phyllosinol is utilized in research applications focused on antifungal drug development and mechanisms of antifungal resistance. -
CYP51 Inhibitor
CYP51-IN-32 is a selective inhibitor of CYP51, demonstrating a potent antifungal activity with an IC50 of 0.331 μM against Candida albicans. This compound not only inhibits the growth of Candida albicans by disrupting hyphal formation and biofilm development, but it also releases hydrogen sulfide (H2S), contributing to its antifungal effects. CYP51-IN-32 is suitable for investigating Candida albicans infections and can be formulated into PEG-based nanovesicles for enhanced delivery in research applications. -
Antibacterial/Antifungal Agent
Geninthiocin is a thiopeptide that primarily targets bacterial and fungal pathogens, exhibiting significant antibacterial and antifungal activities. Its mechanism of action includes the inhibition of protein synthesis, making it a valuable tool for studying microbial resistance and potential therapeutic applications. Geninthiocin is used in research to investigate the efficacy of novel antimicrobial agents and to explore the underlying biochemical pathways involved in microbial infections. -
Anti-Fungal Agent
Cladospolide D is an anti-fungal agent derived from the strain of Cladosporium sp. FT-0012. This compound exhibits significant activity against various fungal species, making it a valuable tool in antifungal research. It is primarily utilized in studies aimed at understanding fungal pathogenicity and developing new antifungal therapies. -
Anti-Fungal Agent
Clavamycin C functions as a potent anti-fungal agent, demonstrating strong activity against Candida species. Its antifungal effects can be antagonized by dipeptides or tripeptides, while amino acids do not diminish its efficacy. Notably, Clavamycin C displays no antibacterial activity and does not inhibit β-lactamase enzymes, making it a specific agent for fungal research applications. -
Anti-Fungal Agent
Cispentacin is an anti-fungal agent that exhibits significant activity against Candida species and other fungi. This compound demonstrates a favorable safety profile, showing no toxicity at doses up to 1 g/kg. It is primarily utilized in research applications focused on the development of treatments for fungal infections. -
Fungal Inhibitor
Prumycin dihydrochloride is an antifungal compound that targets fungal pathogens, specifically demonstrating efficacy against cucumber powdery mildew. This reagent significantly inhibits disease progression while not inducing plant defense gene expression, suggesting its mechanism does not rely on host defensive responses. Additionally, it has shown effectiveness in preventing spore germination of P. fusca, making it valuable for research into fungal pathogenesis and disease management in agriculture. -
CYP51 Inhibitor
(Rac)-Ketoconazole is an imidazole antifungal agent that acts as a potent inhibitor of cytochrome P450-dependent 14α-sterol demethylase (CYP51). By disrupting ergosterol synthesis, it induces membrane dysfunction, thereby inhibiting the growth and reproduction of various fungi. This compound is primarily utilized in research relating to fungal infections and the mechanisms of antifungal resistance. -
Antifungal Compound
Malvone A is an antifungal compound derived from Malva sylvestris that exhibits significant activity against Verticillium dahliae with an ED50 of 24 µg/mL. This compound serves as a valuable tool for research into the development of anti-infective agents and the study of fungal pathogenesis. Its efficacy against pathogenic fungi makes it a noteworthy candidate for investigations focused on antifungal therapies. -
Fungicide Agent
Tecnazene is a dinitroaromatic fungicide that acts as a plant growth regulator. It effectively inhibits the sprouting of potato tuber buds while demonstrating strong antifungal activity against pathogens responsible for dry rot. Additionally, Tecnazene exhibits acute toxicity in Rattus norvegicus and possesses significant harmful effects on aquatic organisms, including freshwater fish and crustaceans. This compound is primarily utilized in agricultural settings for controlling sprouting and managing dry rot in stored potatoes. -
Antimicrobial Agent
Cyclogregatin is an antimicrobial agent with demonstrated antibacterial and antifungal activity. It effectively inhibits the growth of airy ascites carcinoma with a minimum inhibitory concentration (MIC) of 10 μg/mL. This compound is applicable in research settings focusing on microbial resistance and cancer biology. -
Anti-Fungal Agent
Orchinol is an aromatic derivative with potent antifungal activity. This compound targets fungal cell membrane integrity, disrupting the synthesis of ergosterol and ultimately leading to cell death. Orchinol is utilized in research to explore antifungal mechanisms and develop new therapeutic strategies against fungal infections. -
Anti-Fungal Agent
Crocacin D is an anti-fungal agent that exhibits significant activity against both yeast and filamentous fungi. This compound demonstrates the ability to inhibit mouse fibroblast cell line L929, indicating its potential cytotoxic effects. Additionally, Crocacin D disrupts the bc1 segment of the electron transport chain in calf heart microsomes, resulting in a redshift of the 569 nm peak in the cytochrome B reduction spectrum, which highlights its role in mitochondrial function studies. -
Anti-Fungal Agent
Chainin is an anti-fungal agent that exhibits significant activity against yeast and Aspergillus niger. This compound is utilized in research focused on fungal infections and provides valuable insights into the mechanisms of antifungal resistance and therapeutic efficacy. Its effectiveness makes it a critical tool for the study of fungal pathogenesis and potential treatments. -
OSBP Inhibitor
Antifungal agent 107 is an oxysterol-binding protein (OSBP) inhibitor that exhibits antifungal activity. This compound is effective in managing cucumber downy mildew and potato late blight in greenhouse settings, making it a valuable tool for researchers investigating plant pathology and disease control strategies. Its targeted mechanism of action provides a means to explore the role of OSBP in fungal biology. -
Antifungal Agent
Cavipetin C is a diterpene derived from B. cavipes, known for its antifungal properties. This compound effectively inhibits spore formation in Cladosporium cucumericum, making it a valuable tool for studying fungal biology and developing antifungal strategies. Its biological activity supports research in mycology and potential therapeutic applications. -
Macrolide Compound
Dunaimycin A1 is a 24-membered macrolide compound that exhibits immunosuppressive activity. It demonstrates antifungal properties specifically against Aspergillus niger. This compound is valuable for research in the field of autoimmune diseases and can contribute to understanding immune system modulation. -
Antifungal Antibiotic
Pradimicin T1 is an antifungal antibiotic that targets a wide range of filamentous fungi and yeast-like fungi. It exhibits potent antifungal activity, making it a valuable tool in the study of fungal infections and the development of antifungal therapies. Pradimicin T1 is commonly utilized in research applications focusing on fungal biology and mechanisms of resistance.
