Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Fungal Agent
Gladiolic acid is an anti-fungal agent that exhibits potent activity against various fungal species, including Absidia glauca, Byssochlamys fulva, and Trichophyton mentagrophytes. Its efficacy in inhibiting fungal growth makes it a valuable reagent for studies focusing on fungal pathogenesis and the development of antifungal therapies. This compound can serve as a critical tool in research applications aimed at understanding fungal resistance mechanisms and exploring new antifungal strategies. -
Depsidone
Nidulin, a depsidone derived from the marine fungus Aspergillus unguis, exhibits significant antifungal and antibacterial properties. It demonstrates inhibitory activity against pathogenic strains, including Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus, and Candida albicans, with inhibition zones measuring 9.5 mm, 9.0 mm, and 9.0 mm, respectively. Additionally, Nidulin demonstrates potent larvicidal effects against brine shrimp, making it a valuable compound for research in microbial resistance and pest control. -
Anti-Fungal Agent
Chlorflavonin is an antifungal agent that targets a range of fungal pathogens, including Aspergillus, yeast, and Botrytis species. Notably, it exhibits potent activity against Aspergillus fumigatus, with a minimum inhibitory concentration determined at 0.08 μg/mL. This compound is utilized in research applications focused on fungal infection prevention and treatment. -
Antimycotic Photosensitizer
Antifungal Agent 87 is a potent photodynamic therapy (PDT) antimycotic photosensitizer, demonstrating an IC50 of 1 nM against Trichophyton rubrum. This agent induces antifungal effects through light activation, facilitating the generation of reactive oxygen species that damage fungal cells. It holds significant potential for research in fungal infections and the development of novel therapeutic approaches utilizing photodynamic mechanisms. -
Anti-Fungal Agent
Neoenactin B2 is an effective anti-fungal agent targeting yeast-like and filamentous fungi. It exhibits potent inhibitory activity against various fungal strains, making it a valuable compound for studying fungal pathogenesis and evaluating antifungal strategies. This compound is particularly useful in research applications focused on fungal infections and the development of new antifungal therapies. -
Anthraquinone Derivative
Neobulgarone C is an anthraquinone derivative derived from the fungus Neobulgaria pura HA A07-97. It is primarily known for its ability to inhibit the formation of appressorium in Magnaporthe grisea, a significant pathogen in plant biology. Additionally, Neobulgarone C exhibits weak cytotoxicity while demonstrating a lack of antifungal, antibacterial, or phytotoxic activity. This compound is relevant for research applications focused on plant-pathogen interactions and the study of fungal biology. -
Fungal
Frequentin is a secondary metabolite produced by the fungus Penicillium janthinellum, with a notable response to environmental stressors such as cadmium nitrate and sodium chloride. This compound has demonstrated significant biological activity in antifungal assays, suggesting its potential utility in investigating fungal biology and developing antifungal therapies. Research applications may include studying the effects of heavy metals and salinity on metabolite production and exploring the ecological roles of secondary metabolites in fungi. -
Antifungal agent
LY 121019 is a semi-synthetic antifungal antibiotic that exhibits potent activity against Candida species, with a minimum inhibitory concentration (MIC50) of 0.625 μg/mL. This compound is utilized in research focused on fungal infections and resistance mechanisms. Its effectiveness makes it valuable for studies aimed at understanding antifungal therapies and developing new treatment strategies. -
Antifungal Agent
Vaccarin C is a cycloheptapeptide that functions primarily as an antifungal agent. It exhibits potent antifungal activity against pathogenic fungi and dermatophytes, including M. audouinii and T. mentagrophytes, with MIC values as low as 6 µg/mL. Additionally, Vaccarin C demonstrates significant cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines, with IC50 values of 3.35 μM and 5.72 μM, respectively. This compound is useful for research applications in antifungal therapy and cancer biology. -
Anti-Fungal Agent
Clavamycin B is an anti-fungal agent with potent activity against Candida species. Its efficacy is notably antagonized by dipeptides and tripeptides, while amino acids do not affect its action. Clavamycin B does not demonstrate antibacterial activity nor inhibition of β-lactamase, making it a specific choice for studying fungal infections in laboratory settings. -
Antimicrobial Agent
Hypelcin A-I is an antimicrobial agent known for its activity against Gram-negative bacteria and fungi. It demonstrates potent inhibitory effects, making it a valuable tool for researchers studying microbial resistance and the development of new therapeutic strategies. This compound is suitable for various applications in microbiological research, particularly in evaluating antibacterial and antifungal efficacy. -
Anti-Fungal Agent
Chondramide B is an anti-fungal agent that exhibits potent activity against various fungal species, including Candida and several yeast strains such as Henson, lipids yeast, and ball-like yeast. This compound shows selective anti-fungal properties without exhibiting activity against Gram-positive or Gram-negative bacteria. Chondramide B is applicable in research focused on fungal infections and the development of antifungal therapeutics. -
Yck2 Inhibitor
GW461484A is a selective inhibitor of Candida albicans Yck2, demonstrating an IC50 of 0.11 µM. This compound exhibits significant antifungal activity, with a MIC80 of 12.5 µM against C. albicans. GW461484A is valuable for research into fungal infections, particularly those involving drug-resistant strains of Candida. -
Anti-Fungal Agent
Phoslactomycin E is an anti-fungal agent that primarily targets fungal pathogens. It exhibits potent fungicidal activity while demonstrating only limited efficacy against Gram-positive bacteria. This compound is valuable in research applications focused on fungal infections and the development of antifungal therapies. -
Chromone Compound
Isofusidienol A is a chromone compound that exhibits notable antibacterial and antifungal activities. Isolated from Artemisia vulgaris, it demonstrates significant efficacy against Bacillus subtilis and potent activity against Candida albicans. This compound is valuable for research focused on bacterial and fungal infections, providing insights into potential therapeutic applications. -
Antifungal Agent
Antifungal Agent 137 (Compound 4S) primarily targets lanosterol 14α-demethylase (CYP51) and exhibits potent antifungal activity against Phomopsis sp. (PS), with an EC50 of 0.15 μg/mL and an IC50 of 5.00 μg/mL. This compound disrupts the morphology of PS mycelia, impairs cell membrane integrity, and induces oxidative stress by increasing intracellular reactive oxygen species levels. Antifungal Agent 137 is suitable for research applications focused on fungal infections and antifungal mechanisms. -
Fungicide
Pyriofenone is an arylphenyl ketone fungicide targeting a broad spectrum of fungal pathogens. It exhibits significant activity against powdery mildew affecting crops such as cereals, rice, fruit trees, and vegetables, while also demonstrating moderate efficacy against rice blast. Its diverse action mechanisms include preventive, residual, curative, rainfast, and fumigant properties, making it an effective choice for managing fungal diseases in agricultural settings. -
Anti-Fungal Agent
Haematocin is an anti-fungal agent that specifically inhibits the germination of Pyricularia oryzae spores. This compound demonstrates significant biological activity against fungal pathogens, making it a valuable tool for research in plant pathology and antifungal drug development. Its efficacy in preventing spore germination can aid in the exploration of protective strategies against crop diseases. -
Antifungal Agent
Hordatine A is a naturally occurring compound extracted from barley, primarily known for its antifungal properties. It exhibits significant activity against a range of fungal pathogens, making it a valuable tool in the study of fungal infections. Hordatine A is suitable for research applications focused on understanding and combating fungal diseases. -
Yck2 Inhibitor
Yck2-IN-1 is a potent inhibitor of the Yck2 kinase in Candida albicans, exhibiting an IC50 of approximately 80 nM. This compound demonstrates effective antifungal activity, with a MIC80 of 12.5 µM against C. albicans and a favorable metabolic profile, retaining 66% stability in mouse liver microsomes. In preclinical studies, Yck2-IN-1 significantly reduced fungal load in the kidneys of mice with drug-resistant candidiasis, highlighting its potential for research applications in antifungal treatment development. -
Anti-Fungal Agent
Azoxybacilin is an anti-fungal agent that primarily inhibits sulfur fixation in methionine biosynthesis. This compound exhibits significant activity against filamentous fungi, making it useful for research applications in fungal biochemistry and pathogenesis studies. Its mechanism of action may provide insights into sulfur metabolism and antifungal resistance mechanisms. -
Antifungal Agent
Irtemazole is an orally active antifungal agent that primarily targets fungal pathogens. It exhibits a uricosuric effect, enhancing uric acid excretion. This compound is utilized in research addressing fungal infections such as blastomycosis, histoplasmosis, and aspergillosis, making it a valuable tool in the study of antifungal therapies. -
Antifungal Agent
δ-Dodecalactone is a lactone compound with significant antifungal properties. It demonstrates potent activity against a range of molds, including Aspergillus flavus, A. fumigatus, A. petrakii, A. ochraceus, A. nidulans, and Penicillium roqueforti. Due to its strong antifungal effects, δ-Dodecalactone is valuable in research applications focused on mycology and the development of antimicrobial agents. Additionally, it serves as a flavoring compound in various culinary applications. -
Antifungal Agent
Etheroleic acid is an antifungal agent that exhibits potent activity against the powdery mildew fungus B. graminis in barley seedlings. As a metabolite of linolenic acid, it may play a crucial role in plant defense mechanisms and can be utilized in agricultural research to explore its effectiveness against fungal pathogens. -
Antifungal Antibiotic
Dactylfungin B is an antifungal antibiotic with potent activity against Candida pseudotropicalis and various other fungal species, demonstrating a minimum inhibitory concentration (MIC) of less than 10 μg/mL. This compound is valuable for research applications focused on fungal infections, resistance mechanisms, and the development of new antifungal therapies. Its efficacy positions it as a promising candidate for further studies in mycology and pharmacology. -
Antimicrobial Agent
Concanamycin G is a specific inhibitor of the V-type ATPase, with a reported Ki of 0.02 nM. It exhibits a range of biological activities, including antifungal, antiviral, immunosuppressive, and cytotoxic effects. This compound is a valuable tool in biochemical research, particularly in studies involving cellular energy regulation and membrane transport processes. -
Antimicrobial Agent
Neocopiamycin A is an antimicrobial agent that demonstrates broad-spectrum activity against Gram-positive bacteria, yeast, and filamentous fungi. Its robust mechanism of action makes it a valuable tool in the study of antimicrobial resistance and the development of novel antifungal treatments. This compound is suitable for research applications focused on microbiological assays and the exploration of microbial susceptibility. -
Agriculture Fungicide
Azaconazole is a systemic fungicide that targets fungal cytochrome P450 enzymes, inhibiting ergosterol biosynthesis. It exhibits potent antifungal activity against powdery mildew and bean rust, making it effective in agricultural applications. Azaconazole is utilized to protect a variety of crops, ensuring healthier yields and improved plant health. -
Antifungal Agent
Bupirimate is a systemic fungicide that acts as an inhibitor of adenosine deaminase (ADA). It exhibits significant antifungal activity, particularly against powdery mildew, making it valuable in agricultural applications. Bupirimate is utilized in the cultivation of fruit trees, vegetables, and ornamental plants to effectively manage and control fungal infections, thereby enhancing crop yield and health. -
CDA Inhibitor
CDA-IN-4 is a chitin deacetylase (CDA) inhibitor. It demonstrates a protective effect of 61.2% against rice blast disease at a concentration of 100 μg/mL. This compound is pertinent for research applications targeting fungal infections in plants and exploring mechanisms of disease resistance. -
Antifungal Antibiotic
Pradimicin B is an antifungal antibiotic that targets fungal cell membranes. It exhibits significant antifungal and yeast activity, making it valuable for research into fungal infections and potential therapeutic applications. This compound may facilitate studies on the mechanisms of antifungal resistance and the development of new antifungal agents. -
Anti-Fungal Agent
Acrylamidine is an anti-fungal agent that exhibits activity against mold and yeast. This compound can be utilized in research applications aimed at understanding fungal resistance mechanisms and developing new therapeutic strategies for fungal infections. Its weak activity profile makes it a candidate for further modification and study in the pursuit of more potent anti-fungal agents. -
Fungal Inhibitor
Methoxyanigorufone is a fungal inhibitor derived from Musa acuminata var. "Yangambi km 5." This compound exhibits significant antifungal activity, demonstrating effectiveness against a range of pathogenic fungi. It is particularly useful in studies exploring fungal resistance mechanisms and the development of antifungal agents in research applications. -
Anti-Fungal Agent
Enactin Ia is a secondary metabolite derived from the strain of Streptomyces roseoviridis, functioning as an anti-fungal agent. This compound exhibits limited antifungal activity and can be utilized in research related to fungal pathogenesis and the efficacy of antifungal agents. Its characterization contributes to the understanding of microbial metabolites and their potential applications in combating fungal infections. -
BcSDH Inhibitor
SDH-IN-45 is an inhibitor of succinate dehydrogenase (BcSDH) that targets Botrytis cinerea, exhibiting an IC50 of 5.97 μg/mL. This compound impedes fungal energy metabolism through a distinct binding mode, leading to morphological disruptions, including structural collapse and shrinkage of mycelial forms. SDH-IN-45 demonstrates potent in vitro fungicidal activity against Botrytis cinerea, making it a valuable reagent for research focused on cucumber gray mold and related phytopathological studies. -
TMV Inhibitor
TMV-IN-15 is a potent inhibitor of Tobacco Mosaic Virus (TMV) by targeting the TMV coat protein (TMV-CP). This compound effectively suppresses viral particle assembly, leading to significant aggregation and structural fusion of viral components. TMV-IN-15 also demonstrates inhibitory activity against important fungal pathogens such as Physalospora piricola and Rhizoctonia cerealis. This reagent is valuable for research applications in antiviral and antifungal pesticide development. -
Succinate Dehydrogenase Inhibitor
SDH-IN-38 is a potent inhibitor of succinate dehydrogenase, primarily targeting mycelial respiration. Demonstrating significant antifungal activity, SDH-IN-38 exhibits an EC50 value of 0.009 μg/mL against R. solani mycelia, effectively inhibiting mycelial growth. Additionally, this compound induces cellular senescence and reduces mitochondrial membrane potential in fungal cells, making it a valuable tool for research in fungal biology and disease management. -
Anti-Fungal Agent
9-Hydroxyoudemansin A is an antifungal agent that exhibits significant activity against ochre-like yeast, with a minimum inhibitory concentration (MIC) of 12.5 µg/mL. This compound demonstrates resistance to various fungi, including Candida albicans, Crimson Yeast, Penicillium, and Streptomyces, all with MICs greater than 50 µg/mL. It is primarily utilized in research focused on fungal infections and exploring novel antifungal therapies. -
Antifungal Agent
Piperanine is an antifungal agent known for its inhibitory activity against the fungus Cladosporium cladosporioides. Isolated from the fruits of Piper retrofractum, piperanine demonstrates potential in combating fungal infections and can be utilized in research focused on antifungal drug development and therapeutic applications. Its efficacy against specific fungal strains makes it a valuable compound for studies in mycology and agricultural biology. -
Anti-Fungal Agent
Chondramide C functions as an anti-fungal agent, demonstrating significant activity against Candida species, Henson yeast, lipid yeast, and other fungal forms. Its selective spectrum of action shows no efficacy against Gram-positive or Gram-negative bacteria, making it a valuable tool in fungal research and potential therapeutic applications. -
Antifungal Agent
A25822B is an antifungal agent that exhibits a minimal inhibitory concentration (MIC) of 1 μM against Ascosphaera apis. It induces conformational changes in mitochondrial structures while disrupting the integrity of spore membranes. This compound is suitable for research focused on bee chalk disease and related fungal infections. -
Antifungal Agent
Sarisan (Asaricin) is a phenolic compound primarily recognized for its antifungal properties. Extracted from the stem bark of Ocotea opifera Mart., Sarisan exhibits significant activity against various fungal pathogens. This compound is valuable in research applications focused on developing antifungal treatments and investigating the ecological roles of plant-derived antifungals. -
Antimicrobial Agent
Octacosamicin A is an antimicrobial agent that exhibits activity against yeast and filamentous fungi, with moderate efficacy against bacteria. This compound is valuable in studies investigating antifungal mechanisms and the development of novel antimicrobial therapies. Its unique properties make it a potential lead for further research in the field of microbiology. -
Anti-Fungal Agent
6-O-Demethyl-5-deoxyfusarubin is an anti-fungal agent that targets fungal cell growth and proliferation mechanisms. This compound exhibits significant activity against various fungal strains and mycoplasma, making it a valuable tool in anti-fungal research and the development of effective therapeutic strategies. Its efficacy in inhibiting fungal infections highlights its potential applications in microbiology and pharmacology studies. -
Steroidal Sapogenin
Schidigera-genin B is a steroidal sapogenin derived from Yucca glauca. It demonstrates weak antifungal activity and can be utilized in research applications focused on assessing natural compounds with potential therapeutic effects. This compound may serve as a valuable tool in studying sapogenins and their biological roles. -
Anti-Fungal Agent
Phoslactomycin D is an anti-fungal agent that exhibits potent activity against various fungal species. While it demonstrates limited efficacy against Gram-positive bacteria, its primary application lies in targeting fungal infections. This compound is particularly valuable for researchers exploring antifungal mechanisms or developing new treatments for fungal diseases. -
Antifungal Agent
Posaconazole hydrate is a broad-spectrum antifungal agent classified as a second-generation triazole derivative. It exerts its activity by inhibiting the enzyme lanosterol 14α-demethylase, crucial for ergosterol synthesis in fungal cell membranes. This compound is particularly effective against various fungal pathogens and is utilized in both in vitro and in vivo studies to explore its efficacy in treating invasive fungal infections. -
Anti-Fungal Agent
Haliangicin D is an anti-fungal agent with potent activity against filamentous fungi and oomycetes. It does not exhibit antibacterial properties. This compound is valuable in research applications exploring fungal infections and the mechanisms of fungal pathogenicity. -
Diffusion Signaling Factor
trans-11-Methyl-2-dodecenic acid is an isomer of cis-11-Methyl-2-dodecenoic acid and functions as a diffusion signaling factor (DSF) in microbial and fungal communication. It plays a crucial role in quorum sensing (QS), facilitating extracellular interactions among microbial populations. This compound is significant for studies on microbial ecology and can be utilized to investigate signaling mechanisms in various biological systems. -
Calcineurin Inhibitor
JH-FK-08 is a potent inhibitor of the serine/threonine-specific phosphatase calcineurin. It demonstrates significant antifungal activity against Cryptococcus neoformans, with a MIC80 of 0.8 µg/mL, and displays immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 also shows efficacy in mouse models for anti-infectious applications, making it valuable for research in immunology and infectious disease.
