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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Lavendamycin is a quinolinedione with antimicrobial properties, primarily acting as a bacterial inhibitor. It demonstrates significant antibacterial and antitumor activity, making it a valuable compound for research in microbiology and cancer biology. Its unique mechanism and efficacy position Lavendamycin as a potential tool for exploring therapeutic approaches against bacterial infections and tumors. -
Bacterial Inhibitor
Dodine is a bacterial inhibitor with fungicidal properties, primarily targeting various plant pathogens. It is effective in controlling diseases such as black spot in apples, pears, and pecans, as well as brown rot in peaches, along with a range of foliar diseases affecting strawberries, cherries, jacaranda, and black walnuts. In addition to its agricultural applications, Dodine serves as an industrial biocide and preservative, making it valuable in diverse research settings focused on plant disease management and microbial control. -
Bacterial Inhibitor
Meso-2,6-Diaminopimelic acid serves as a critical biosynthetic precursor in the synthesis of the essential amino acid L-lysine. It plays a vital role in the formation of peptidoglycan, a key structural component of the cell walls in various bacterial species. This compound is primarily utilized in research related to bacterial inhibition and the study of cell wall biosynthesis, making it essential for antimicrobial investigations and the development of antibacterial agents. -
Bacterial Inhibitor
D-Homoserine lactone is a bacterial inhibitor that functions as a signaling molecule regulating quorum sensing through its interaction with acyl-homoserine lactone (AHL) synthase RhlI. By inhibiting RhlI activity, D-Homoserine lactone disrupts bacterial communication, making it a valuable tool in studies of bacterial behavior and pathogenicity. Additionally, as an enantiomer of L-homoserine lactone, it serves as an inhibitor of serine hydroxymethyltransferase, expanding its potential applications in biochemical research and synthetic biology. -
Bacterial Inhibitor
Afabicin disodium is a specialized bacterial inhibitor that functions as a proagent for Debio1452. It specifically targets Staphylococcus species while exhibiting minimal activity against other Gram-positive and Gram-negative bacteria. The active form, Debio1452, is an inhibitor of FabI, an enzyme essential for fatty acid biosynthesis in staphylococci, making it a valuable tool for research in combating staphylococcal infections. -
Bacterial Inhibitor
Epinecidin-1 is a potent antimicrobial peptide derived from the orange-spotted grouper (Epinephelus coioides), targeting various bacterial strains. It exhibits substantial antibacterial, antifungal, antiviral, and antiprotozoal activity, making it a valuable tool in studies examining microbial inhibition. Additionally, its immunomodulatory and wound healing properties further support research applications in infection control and regenerative medicine. -
Bacterial Inhibitor
Tuberculosis Inhibitor 3 (Compound 2i) is a potent antibacterial agent targeting Mycobacterium tuberculosis, demonstrating a minimum inhibitory concentration (MIC) of less than 0.016 μg/mL against both sensitive and resistant strains. This compound exhibits favorable pharmacokinetic properties, including adequate oral bioavailability, making it a promising candidate for further research and development in tuberculosis treatment strategies. -
Bacterial Translation Inhibitor
NOSO-502 is a bacterial translation inhibitor that targets ribosomal activity in Enterobacteriaceae. It demonstrates potent antibacterial properties while maintaining a favorable safety profile. This compound is suitable for research applications focused on bacterial protein synthesis and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Antitubercular agent-10 is a bacterial inhibitor that demonstrates potent antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 30 nM. This compound is primarily utilized in research focused on combating tuberculosis, enabling investigations into its mechanisms of action and potential therapeutic strategies. Its effectiveness makes it a valuable tool for studying mycobacterial infections and the development of novel antitubercular therapies. -
Bacterial Inhibitor
CGI-17341 is a 5-nitroimidazole antibacterial agent targeting bacterial pathogens, specifically Mycobacterium tuberculosis. This compound demonstrates significant inhibitory activity against both sensitive and multidrug-resistant strains of M. tuberculosis in vitro. In vivo studies indicate that CGI-17341 can prolong the survival time of infected mice in a dose-dependent manner, making it a valuable tool for research on tuberculosis and related bacterial infections. -
Bacterial Inhibitor
Cephabacin M4 is a cephalosporin derivative, specifically a 7-methoxydesacetylcephalosporin, that functions as a bacterial inhibitor. It exhibits significant antimicrobial activity against a range of bacterial pathogens, making it valuable for research involving antibiotic development and bacterial resistance studies. Isolated from the culture filtrate of Xanthomonas lactamica, Cephabacin M4 serves as a useful tool in exploring cephalosporin efficacy and mechanisms of action. -
Bacterial Inhibitor
Antibacterial agent 202 (compound 45c) is a bacterial inhibitor that targets Gram-negative bacteria, demonstrating significant antibacterial activity against strains such as Escherichia coli, Klebsiella pneumoniae, and especially Pseudomonas aeruginosa, with a minimum inhibitory concentration (MIC) ranging from 7.8 to 31.25 μM. This compound functions by disrupting the integrity of bacterial cell membranes, making it a valuable tool for research into bacterial infections and potential therapeutic applications. -
Bacterial Inhibitor
BPH-651 is a bacterial inhibitor that targets dehydrosqualene synthase, an essential enzyme involved in bacterial terpenoid biosynthesis. This compound exhibits potent antibacterial activity by binding to multiple sites on the enzyme, revealing structural insights into the mechanism of action and inhibition of head-to-head prenyltransferase. BPH-651 is useful for research focused on designing new antibacterial agents and studying bacterial resistance mechanisms. -
Bacterial Inhibitor
Antistaphylococcal agent 1 functions as a bacterial inhibitor, specifically targeting Staphylococcus species. This compound exhibits significant antimicrobial activity, making it a valuable tool in the study of bacterial infections and resistance mechanisms. Its application can aid in the development of novel therapeutic strategies against staphylococcal infections. -
Bacterial Inhibitor
(Rac)-DNDI-8219 is a bacterial inhibitor with demonstrated efficacy against Leishmania species. This compound exhibits potent antituberculosis and anti-leishmanial activities, showcasing significant effectiveness in both the Leishmania donovani mouse model and the Leishmania infantum hamster model. Interestingly, the R-6 candidate form of (Rac)-DNDI-8219 offers excellent oral bioavailability and efficacy in the hamster model, making it a valuable tool for research focused on treating leishmaniasis and tuberculosis. -
Bacterial Inhibitor
Acaterin is a bacterial inhibitor derived from Pseudomonas, known for its role in antimicrobial activity. Research indicates that its biosynthesis is regulated through a complex gene cluster, with studies highlighting its associated biosynthetic pathway. Comparative transcriptomics further demonstrates the compound's formation is intricately linked to bacterial regulatory networks, making it valuable for studies in bacterial physiology and the development of new antimicrobial strategies. -
Bacterial Inhibitor
8-Epidiosbulbin E acetate is a furanoid compound derived from Dioscorea bulbifera L. It functions as a bacterial inhibitor, demonstrating broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. Additionally, it has been noted to induce liver injury in murine models, highlighting its potential impact on liver function. This compound is valuable for research involving antibiotic resistance and bacterial pathogenicity. -
Bacterial Inhibitor
FtsZ-IN-10 is a bacterial division inhibitor that targets the assembly of FtsZ, a critical protein involved in bacterial cytokinesis. By binding specifically to Bacillus subtilis FtsZ monomers, FtsZ-IN-10 disrupts their polymerization, ultimately hindering the formation of the Z ring and inhibiting cell division. This compound has demonstrated efficacy against antibiotic-resistant clinical isolates, including Staphylococcus aureus and Enterococci, making it a valuable tool in microbiological research and antibiotic development. Additionally, FtsZ-IN-10 may stimulate nucleotide-free archaeal FtsZ to form structured polymers, contributing to its versatile applications in studying bacterial growth and division mechanisms. -
Bacterial Inhibitor
Ianthelliformisamine C ditrifluoroacetate is a bacterial inhibitor that enhances the activity of antibiotics against resistant Gram-negative bacteria. This compound has been shown to significantly improve the efficacy of doxycycline against Pseudomonas aeruginosa. Its mechanism of action involves inducing ATP efflux and causing membrane depolarization in bacterial cells. Ianthelliformisamine C ditrifluoroacetate is synthesized using peptide coupling, resulting in high chemical yields ranging from 27% to 91%, making it a valuable tool for research in combating antibiotic resistance. -
Bacterial Inhibitor
Protactin is a pentapeptide lactone that targets bacterial growth, derived from the Streptomyces cucumeris strain L703-4 (ATCC 53784). This compound demonstrates significant antioxidant properties and can be converted to actinomycin Zp through ferrocyanide oxidation, which displays potent antibacterial activity in vitro. Additionally, actinomycin Zp has been shown to possess substantial antitumor effects against P-388 leukemia in murine models, making it a valuable reagent for cancer research and microbiological studies. -
Bacterial Inhibitor
Cyclo(Leu-Ala) is a cyclic dipeptide with demonstrated antimicrobial properties targeting bacterial pathogens. This compound exhibits significant inhibitory activity against various plant pathogens, making it a valuable tool in studies involving plant-microbe interactions and the development of novel antimicrobial agents. Its potential applications include agricultural research and the investigation of natural products for controlling plant diseases. -
Bacterial Inhibitor
Haplopine is a bacterial inhibitor that exhibits photo-activated antimicrobial properties. It demonstrates the ability to bind to DNA, making it a valuable tool for research applications focused on bacterial infections and microbial resistance. This compound is beneficial in studies investigating the mechanisms of antimicrobial action and the potential development of novel therapeutic strategies. -
Bacterial Inhibitor
Forphenicinol is a bacterial inhibitor that acts as an immunomodulator, derived from the bacterial metabolite forphenicine. It enhances the phagocytic activity of peritoneal macrophages and is effective in mitigating cyclophosphamide-induced suppression of delayed-type hypersensitivity (DTH) in murine models. Forphenicinol increases macrophage bactericidal activity against Pseudomonas aeruginosa and improves survival rates in mouse models of P. aeruginosa infection. Additionally, it demonstrates anti-tumor effects in S180 sarcoma and IMC carcinoma xenograft models, with effective dosing ranging from 0.05 to 5 mg/kg per day. -
Bacterial Inhibitor
Glyasperin D is a flavonoid derived from Glycyrrhiza uralensis that demonstrates antibacterial properties, specifically as a bacterial inhibitor against Helicobacter pylori. Its biological activity suggests potential applications in research focused on bacterial infections and the development of antibacterial agents. This compound may serve as a valuable tool in studying H. pylori-related diseases and exploring flavonoid mechanisms in bacterial inhibition. -
Bacterial Inhibitor
JM 1397 is a potent antibacterial agent with a primary mechanism of action against bacterial pathogens. It demonstrates significant antibacterial activity against both methicillin-susceptible and methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC90) of 1 μg/mL. This compound is valuable for research in antibiotic resistance and the development of new antimicrobial therapies. -
Bacterial Inhibitor
Gyramide A is a bacterial inhibitor that targets bacterial topoisomerases. It has been shown to exhibit a unique mechanism of action distinct from other topoisomerase inhibitors, highlighting its potential in studies related to bacterial resistance. Gyramide A is valuable for research applications aimed at understanding the protective effects of Qnr proteins on bacterial enzymes and developing novel antibacterial strategies. -
Bacterial Inhibitor
Acorafloxacin hydrochloride is a broad-spectrum fluoroquinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV. It exhibits potent activity against a range of Gram-positive bacteria, with a mean MIC90 value of 0.12 mg/L. This compound is particularly relevant for research on acute bacterial skin infections and community-acquired pneumonia, as well as the investigation of methicillin-resistant Staphylococcus aureus (MRSA) infections. -
Bacterial Inhibitor
Targeting the bacterial sliding clamp peptide 46 is a short peptide designed to inhibit the bacterial sliding clamp (SC). By interfering with SC-dependent DNA synthesis, this peptide serves as a valuable tool for studying bacterial replication mechanisms and developing novel antibacterial strategies. Its application in research underscores its potential utility in exploring bacterial growth and resistance pathways. -
Bacterial Inhibitor
Cephabacin M6 is a 7-methoxydesacetylcephalosporin that acts as a bacterial inhibitor. It is isolated from the culture filtrate of Xanthomonas lactamica and exhibits significant antibacterial activity against various bacterial strains. This compound is useful in microbiological research for studying antibiotic mechanisms and resistance patterns in bacteria. -
Bacterial Inhibitor
Lascufloxacin hydrochloride is a potent antibacterial compound that targets bacterial DNA gyrase and topoisomerase IV, exhibiting broad-spectrum activity against diverse clinical isolates. It demonstrates robust efficacy against Gram-positive bacteria, outperforming other quinolone derivatives. Notably, Lascufloxacin hydrochloride shows incomplete cross-resistance to certain quinolone-resistant strains, making it a valuable candidate for further investigation. Its ability to inhibit both wild-type and mutated target enzymes underscores its potential in tackling resistant bacterial infections in research settings. -
Bacterial Inhibitor
Antibacterial Agent 63 is a conjugate of aztreonam and a siderophore mimetic, designed to inhibit gram-negative bacteria. This compound exhibits a significant antibacterial activity by targeting bacterial cell wall synthesis, providing a mechanism that enhances its effectiveness against resistant strains. It is suitable for research applications aimed at studying bacterial infections and antibiotic resistance mechanisms. -
Bacterial Inhibitor
DA-7867 is an antibacterial compound that targets a broad spectrum of bacterial strains, including those that are drug-resistant. This amide analog of Tedizolid demonstrates significant antibacterial activity against key clinically relevant pathogens, highlighting the potential of tetrazoles in the discovery of novel antibacterial agents. Its efficacy makes DA-7867 a valuable tool for research into bacterial infections and antibiotic resistance. -
Bacterial Inhibitor
Ro 24-6392 is an ester-linked co-drug that combines Ciprofloxacin and Desacetylcefotaxime, targeting inhibition of bacterial growth. It demonstrates potent antibacterial activity against a range of aerobic bacteria in vitro, making it a valuable tool for microbiological research and studies focused on bacterial resistance mechanisms. This compound can be utilized in the development of novel antibacterial therapies and for evaluating bacterial susceptibility to co-drug formulations. -
Bacterial Inhibitor
Apalcillin is a bacterial inhibitor designed to target and disrupt the activity of various gram-negative bacteria, particularly those that produce β-lactamase. In combination with Ro 48-1220, a β-lactamase inhibitor, Apalcillin exhibits broad-spectrum activity, effectively inhibiting strains such as Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with minimum inhibitory concentrations as low as 11 μg/mL. This combination also shows significant effectiveness against Pseudomonas aeruginosa and Stenotrophomonas maltophilia at even lower MICs (0.25 to 4 μg/mL). However, its efficacy against certain gram-positive organisms remains limited, making it a valuable tool for research on β-lactamase resistance. -
Bacterial Inhibitor
Phenyl(9H-purin-6-yl)amine is an antibacterial compound that targets bacterial growth by inhibiting various cellular processes. This reagent exhibits significant antibacterial activity and is useful in the development of novel antibacterial agents. Its potential inhibitory effects make it a valuable tool for medical research focused on combating bacterial infections. -
Bacterial Inhibitor
Radicinol is a bacterial inhibitor derived from the metabolite of Cochliobolus lunata. It demonstrates potent antimicrobial activity, particularly against various strains of bacteria, making it a valuable tool for research in microbiology and drug development. Radicinol can be utilized to study bacterial resistance mechanisms and assess the efficacy of new antibacterial agents. -
Bacterial Inhibitor
Trimethylsilyl-L-(+)-rhamnose acts as a bacterial inhibitor through its structural similarity to natural rhamnose, playing a crucial role in the study of bacterial cell wall composition. This modified sugar is utilized to investigate the biological functions associated with bacterial growth, providing insights into mechanisms of resistance. Researchers can leverage Trimethylsilyl-L-(+)-rhamnose to enhance understanding of bacterial physiology and the implications for antibiotic development. -
Bacterial Inhibitor
Urechistachykinin II is a tachykinin-related peptide (TRP) derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating a lack of hemolytic effect, making it a valuable tool in the study of bacterial inhibition. Its unique properties may support research in microbial resistance and novel antimicrobial strategies. -
Bacterial Inhibitor
1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine (21:0 PC) functions as a surfactant with notable antibacterial properties. It exhibits efficacy by acting in mucus to inhibit the dissemination of pathogens. Additionally, 1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine contributes to the stability of biofilms, supporting the overall health of associated organisms. This compound is applicable in studies focused on bacterial inhibition and biofilm dynamics. -
Bacterial Inhibitor
Antibacterial Agent 240 (compound 62-7c) is a bacterial inhibitor specifically designed to target multidrug-resistant (MDR) strains of Methicillin-resistant Staphylococcus aureus (MRSA). This compound demonstrates significant antibacterial efficacy, as evidenced by its potent anti-infection activity in preclinical mouse models of pneumonia and wound infections caused by MRSA. Its favorable biosafety profile further supports its potential use in therapeutic applications against resistant bacterial infections. -
Bacterial Penicillin-binding Protein (PBPs) Inhibitor
J-114870 is an inhibitor of bacterial penicillin-binding proteins (PBPs), demonstrating significant efficacy against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS). This compound is valuable for research applications focused on bacterial infections, particularly in understanding resistance mechanisms and developing new therapeutic strategies. -
Bacterial Inhibitor
Antistaphylococcal agent 2 is a bacterial inhibitor targeting Staphylococcus species. It exhibits potent antimicrobial activity, making it effective in combating staphylococcal infections. This compound is primarily utilized in research applications aimed at understanding and developing therapies for bacterial resistance and infection control. -
Bacterial Inhibitor
Antibacterial agent 31 is a bacterial inhibitor that demonstrates significant antibacterial activity against rice bacterial leaf streak. This compound is essential for research applications focused on plant pathology and the development of disease-resistant agricultural practices. Its mechanism of action provides insights into bacterial resistance mechanisms and potential strategies for crop protection. -
Bacterial Inhibitor
Antibacterial agent 249 is a bacterial inhibitor that exhibits broad-spectrum antimicrobial properties. It effectively inhibits the growth of various pathogens including Aspergillus niger, Bacillus subtilis, Pseudomonas albicans, Escherichia coli, and Staphylococcus aureus. Additionally, it displays anti-inflammatory activity in vitro, highlighting its potential applications in the treatment of bacterial infections. -
Bacterial Inhibitor
Kipukasin D is a natural nucleoside derived from Aspergillus versicolor, exhibiting potent antibacterial activity. It operates primarily as a bacterial inhibitor, making it valuable for research involving bacterial infections and microbial resistance mechanisms. This compound is useful for studies in pharmacology, microbiology, and drug development focused on identifying new antimicrobial agents. -
Bacterial Inhibitor
Antistaphylococcal agent 3 is a bacterial inhibitor that targets Staphylococcus species, disrupting their growth and proliferation. This compound exhibits potent antimicrobial activity, making it suitable for research applications focused on bacterial infection models and therapeutic development. Its efficacy against resistant strains renders it valuable for studies aimed at understanding staphylococcal pathogenesis and developing novel antibacterial strategies. -
Bacterial Inhibitor
DS-8587 is a novel fluoroquinolone designed as a bacterial inhibitor, demonstrating significant antibacterial activity against amoxicillin-resistant Bacillus strains. Its minimum inhibitory concentration (MIC) values outperform those of ciprofloxacin and levofloxacin, while exhibiting reduced susceptibility to efflux pump-mediated resistance mechanisms such as adeA/adeB/adeC and abeM. Additionally, DS-8587 has a lower single-step mutation frequency compared to ciprofloxacin, positioning it as a promising therapeutic candidate for the treatment of amoxicillin-resistant Bacillus infections. -
Bacterial Inhibitor
Urechistachykinin I is a tachykinin-related peptide derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating no hemolytic effects, making it a valuable reagent for research into antimicrobial mechanisms and agents. Its unique properties make it suitable for studies investigating bacterial inhibition in various biological contexts. -
Bacterial Inhibitor
(Z)-Ligustilide acts as a bacterial inhibitor with demonstrated antimicrobial and antifungal properties. Extracted from Ligusticum chuanxiong Hort, it has shown an average antifungal score of 5.6. This compound inhibits the expression of FATP5 and DGAT, thereby reducing fatty acid uptake and esterification, positioning it as a potential therapeutic agent for nonalcoholic fatty liver disease (NAFLD). Additionally, (Z)-Ligustilide is involved in reactivating ERα and exhibits epigenetic regulatory functions, making it relevant for research into tamoxifen-resistant breast cancer. -
Bacterial Inhibitor
Roseoflavin is a bacterial inhibitor, functioning as an antimetabolite analog of riboflavin and flavin mononucleotide. This natural pigment, originally extracted from Streptomyces davawensis, exhibits potent antimicrobial properties. It is commonly utilized in research applications aimed at studying bacterial metabolism and the mechanisms of antibiotic resistance.
