(Z)-Ligustilide acts as a bacterial inhibitor with demonstrated antimicrobial and antifungal properties. Extracted from Ligusticum chuanxiong Hort, it has shown an average antifungal score of 5.6. This compound inhibits the expression of FATP5 and DGAT, thereby reducing fatty acid uptake and esterification, positioning it as a potential therapeutic agent for nonalcoholic fatty liver disease (NAFLD). Additionally, (Z)-Ligustilide is involved in reactivating ERα and exhibits epigenetic regulatory functions, making it relevant for research into tamoxifen-resistant breast cancer.
(Z)-Ligustilide acts as a bacterial inhibitor with demonstrated antimicrobial and antifungal properties. Extracted from Ligusticum chuanxiong Hort, it has shown an average antifungal score of 5.6. This compound inhibits the expression of FATP5 and DGAT, thereby reducing fatty acid uptake and esterification, positioning it as a potential therapeutic agent for nonalcoholic fatty liver disease (NAFLD). Additionally, (Z)-Ligustilide is involved in reactivating ERα and exhibits epigenetic regulatory functions, making it relevant for research into tamoxifen-resistant breast cancer.
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