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J-114870

Catalog No.: A49034
Bacterial Penicillin-binding Protein (PBPs) Inhibitor
J-114870 is an inhibitor of bacterial penicillin-binding proteins (PBPs), demonstrating significant efficacy against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS). This compound is valuable for research applications focused on bacterial infections, particularly in understanding resistance mechanisms and developing new therapeutic strategies.
J-114870 228267-11-6 Bacterial Penicillin-binding Protein (PBPs) Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJ-114870 is an inhibitor of bacterial penicillin-binding proteins (PBPs), demonstrating significant efficacy against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS). This compound is valuable for research applications focused on bacterial infections, particularly in understanding resistance mechanisms and developing new therapeutic strategies.
Product Information
Catalog NumA49034
FormulaC23H31ClN4O5S
Molecular Weight511.03
CAS Number228267-11-6
SMILESOC(C1=C(S[C@H]2C[C@H](C3=CC=C([C@@H](N)CC(N)=O)C=C3)NC2)[C@H](C)[C@@]([C@@]4([H])[C@H](O)C)([H])N1C4=O)=O.Cl
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Microbiology > Antifection > Bacterial