Catalog No.
Product Name
Application
Product Information
Citations
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ATPase and GTPase inhibitor
Etidronate Disodium is a bisphosphonate bone resorption inhibitor. -
anti-cancer agent
Ginsenoside Rc, isolated from Panax ginseng, may exert various activities including anti-cancer, anti-inflammatory, antiobesity, and anti-diabetic effects. -
STAT3 inhibitor
Corylifol A is a phenolic compounds isolated from Psoralea corylifolia; inhibits IL-6-induced STAT3 activation and phosphorylation(IC50=0.8 uM). - 6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.
- Salvianolic Acid B is isolated and purified from the crude extract of Salvia miltiorrhiza.
- Budesonide is a glucocorticoid steroid for the treatment of asthma and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. In addition, it is used for Crohn's disease (inflammatory bowel disease).
- Manool is a labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13. It has a role as an antineoplastic agent, a plant metabolite and an antibacterial agent. It is a labdane diterpenoid and a tertiary alcohol.
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Pdia3/ERp57 activator, STAT3 inhibitor
Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis . - Coumarin 30 is useful as laser dye. Efficient laser dye for pulsed and CW operation.
- Armillarisin A is a regulator and promotor of immune functions. It acts by enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
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biomarker
2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker. - Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent.
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Apoptosi Inducer
4-Vinylphenol (10% in Propylene Glycol) is a potent apoptosis inducer targeting cancer cell viability and angiogenesis. Extracted from the medicinal herb Hedyotis diffusa and produced by lactic acid bacteria during the metabolism of p-coumaric and ferulic acid, this compound demonstrates significant anti-cancer activity. It inhibits blood vessel formation and suppresses the growth of invasive breast tumors in vivo, making it a valuable tool for cancer research and therapeutic studies. -
Multifunctional Natural Flavonoid Glycoside
Rutin trihydrate is a multifunctional natural flavonoid glycoside primarily known for its antioxidant and anti-inflammatory properties. This compound exhibits significant activity in countering diabetic complications and shows potential anti-carcinogenic effects. Research applications for rutin trihydrate include investigations into cardioprotection and neuroprotection, making it a valuable reagent for studies in various areas of health and disease. -
Human Milk Oligosaccharide
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide known for its antiviral and antibacterial properties. It acts by reducing the capsid protein VP1, thereby blocking virus adsorption, and promotes the regulation of CDK2 and cyclin E to restore the S phase of the cell cycle. Additionally, LNFPI inhibits reactive oxygen species (ROS) production and apoptosis in virus-infected cells. Its ability to regulate intestinal microbiota also highlights its potential role in influencing immune system development. -
Flavonoid compound
Isoxanthohumol is a flavonoid compound known for its diverse biological activities, including anti-tumor, anti-inflammatory, antioxidant, antiviral, and antifungal properties. This compound has been shown to induce apoptosis, autophagy, and cell migration in tumor cells, making it a valuable tool for cancer research. Additionally, Isoxanthohumol exhibits efficacy against various viruses, including HSV, BVDV, CMV, and rhinovirus. It is applicable in studies related to tumors, metabolic disorders, and inflammatory diseases. -
Diterpenoid
Lasiokaurin is a diterpenoid compound that exhibits a range of biological activities. Isolated from Isodon lasiocarpus, it has been studied for its potential anti-inflammatory and anticancer properties. This compound serves as a valuable tool in chemical research focused on natural products and their therapeutic applications. -
Quaternary Isoquinoline Alkaloid
Columbamine chloride is a quaternary isoquinoline alkaloid known for its biological activity as a cytochrome P450 (CYP) isoform CYP3A4 inhibitor, with an IC50 of 30.6 µM. This compound induces apoptosis in cancer cells and exhibits a range of biological effects, including antioxidant, anti-inflammatory, antitumor, antifungal, antiparasitic, hepatoprotective, neuroprotective, hypolipidemic, and hypoglycemic properties. Columbamine chloride is suitable for various research applications focusing on cancer biology, metabolic disorders, and neuroprotection. -
Vnca Alkaloid
Vindoline, a vinca alkaloid, primarily targets tubulin by exhibiting a weak inhibitory effect on its self-assembly. Derived from the leaves of Catharanthus roseus, Vindoline demonstrates biological activity in modulating apoptosis and inhibiting key signaling pathways involving p-p65 and p-ERK. This compound has potential applications in research related to diabetes, bone loss, osteoarthritis, and kidney damage. -
Sesquiterpenoid
ar-Turmerone is a sesquiterpenoid derived from the herb Curcuma longa, known for its anti-tumorigenic and anti-inflammatory properties. It has been shown to induce apoptosis in U937 cells and positively modulate murine dendritic cells. Additionally, ar-Turmerone promotes neural stem cell proliferation in both in vitro and in vivo studies, making it useful for research on various neurological disorders. -
Triterpenoid
Gypenoside A is a triterpenoid compound derived from Gynostemma pentaphyllum, known for its anti-inflammatory and antioxidant properties. This compound exhibits protective effects on cardiomyocytes by inhibiting apoptosis, making it a valuable tool in studying cardiovascular diseases. Additionally, Gypenoside A is relevant for research into inflammation-related disorders, contributing to the understanding of various pathophysiological mechanisms. -
Methoxyflavonoid
Pachypodol is a methoxyflavonoid that primarily activates the ERK-dependent Nrf2 pathway while inhibiting apoptosis. This compound exhibits notable biological activities, including antioxidant, cytoprotective, and anti-inflammatory effects. Research applications include its potential to enhance cognitive function and provide protective effects against cardiac and liver damage. Additionally, Pachypodol demonstrates anticancer activity, particularly against colon cancer, making it a valuable reagent for various biomedical studies. -
Flavonoid
PERK/eIF2α activator 1 is a flavonoid that primarily activates the PERK-eIF2α-ATF4 signaling pathway, exerting significant anti-tumor activity. This compound effectively induces apoptosis in cancer cells and shows a notable inhibition of HepG2 cell proliferation, with an IC50 value of 23 μM. Its mechanism and biological effects make it a valuable tool for research in cancer biology and therapeutic development. -
Diterpenoid Compound
Ferruginol, a natural diterpenoid compound, primarily acts as an inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation. This compound exhibits significant biological activity by inducing mitochondrial apoptosis, which contributes to its efficacy against thyroid cancer cells. Additionally, Ferruginol demonstrates antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective properties, making it a valuable reagent for cancer research and studies on cellular protection mechanisms. -
Triterpenoid Aglycone
Soyasapogenol A is a triterpenoid aglycone derived from soyasaponins. It exhibits notable anti-inflammatory, anti-cancer, and hepatoprotective properties, along with antiviral activity against HSV-1. This compound is valuable for research applications focusing on tumor biology and immune-inflammatory diseases. -
Alkaloid
(Z)-Indirubin is a bis-indole alkaloid that primarily targets multiple signaling pathways associated with cancer progression. This compound exhibits significant anticancer activity, particularly against chronic myelogenous leukemia (CML). Researchers can utilize (Z)-Indirubin for investigations into cancer biology and the development of novel therapeutic strategies targeting CML and other malignancies influenced by similar pathways. -
Cucurbitane-Type Triterpenoid
25-Deacetylcucurbitacin A is a Cucurbitane-Type triterpenoid that targets the JAK/STAT3 signaling pathway. It exhibits significant potential as an anti-cancer agent, demonstrating the ability to inhibit tumor growth and promote apoptosis in malignant cells. This compound can be utilized in research focused on cancer therapeutics and the modulation of tumor-related signaling pathways. -
Phenolic Compound
Cardanol monoene is a phenolic compound derived from cashew nut shell liquid, primarily targeting cellular mechanisms involved in cancer progression. It exhibits significant anti-cancer activities, including the inhibition of cell proliferation and migration, S phase arrest, and induction of apoptosis via reactive oxygen species (ROS) production and mitochondrial depolarization. Cardanol monoene modulates key signaling pathways by downregulating MMP-2 and MMP-9 expressions and regulating the expression of CDK2, p53, and Bax, among others. Additionally, it demonstrates weak DPPH radical scavenging and acetylcholinesterase inhibition activities, making it suitable for research in cancer, infection, and inflammation. -
2-Hydroxycinnamaldehyde
(E)-2-Hydroxycinnamaldehyde is an aldehyde primarily targeting the STAT3 signaling pathway. It exhibits significant biological activity by inhibiting cell proliferation and inducing apoptosis through the modulation of reactive oxygen species production. This compound is valuable in cancer research, demonstrating antitumor effects and potential therapeutic applications in oncological studies. -
Quaternary Isoquinoline Alkaloid
Columbamine is a quaternary isoquinoline alkaloid that acts primarily by inhibiting the cytochrome P450 isoform CYP3A4, with an IC50 of 30.6 µM. This compound demonstrates significant biological activities, including the induction of apoptosis in cancer cells, as well as antioxidant, anti-inflammatory, antitumor, antifungal, antiparasitic, hepatoprotective, neuroprotective, hypolipidemic, and hypoglycemic effects. It is suitable for various research applications exploring therapeutic interventions and mechanisms in cancer and metabolic diseases. -
Natural Product
Ginsenoside F4 (GF4) is a natural product derived from notoginseng and red ginseng, with a primary mechanism of inducing apoptosis in human lymphocytoma JK cells. GF4 demonstrates biological activity by inhibiting the expression of matrix metalloproteinase 13 (MMP-13) in interleukin-1β-treated chondrocytes. This compound shows promise in therapeutic applications aimed at preventing cartilage breakdown and preserving collagen matrix integrity in diseased tissues, particularly in cartilage research. -
Flavonoid
5,6,7,8,4'-Pentahydroxyflavone is a flavonoid with demonstrated antitumor activity. It exerts cytotoxic effects through the inhibition of cell proliferation and the induction of apoptosis. This compound is valuable for cancer research, facilitating studies on cellular mechanisms and potential therapeutic applications in oncology. -
Phenolic Compound
Hydroxytyrosol-d4 is a deuterium-labeled derivative of Hydroxytyrosol, a phenolic compound abundant in olive oil. This compound exhibits antioxidant properties, mitigating oxidative stress and enhancing mitochondrial function, which contributes to its neuroprotective effects. Hydroxytyrosol-d4 is involved in promoting apoptosis in cancer cells through the production of reactive oxygen species (ROS) and demonstrates antibacterial and antiviral activities. It serves as an important tool in research on cancer, infections, inflammation, immunology, metabolic conditions, neurology, and cardiovascular diseases, including colon cancer, diabetes, Alzheimer’s disease, and atherosclerosis. -
Active Alkaloid
Neoechinulin A is an isoprenyl indole alkaloid that primarily acts as an active scavenger. This compound demonstrates neurotrophic factor-like properties and exhibits anti-apoptotic effects. Research indicates that Neoechinulin A can enhance memory and produce antidepressant-like effects in murine models, making it a valuable tool for investigations in neurobiology and mental health studies. -
Natural Product
Pectic acid, a polygalacturonic acid, primarily targets cancer cells by inducing apoptosis and necrosis in pituitary tumor cells. Its key biological activity makes it a valuable reagent in cancer research and studies related to autoimmune diseases. Pectic acid's role in modulating cellular processes provides useful insights into therapeutic strategies for various malignancies and immune disorders. -
Anticancer Agent
Sotetsuflavone is a flavonoid extracted from Cycas revolute, primarily targeting cancer cell migration and invasion. It has been shown to reverse epithelial-mesenchymal transition (EMT), induce apoptosis, and activate autophagy in A549 lung cancer cells. Additionally, Sotetsuflavone downregulates key factors such as HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13, contributing to its anticancer properties. This compound is also investigated for its protective effects in models of Crohn's disease-like colitis, making it a valuable reagent for research in non-small cell lung cancer (NSCLC) and inflammatory bowel diseases. -
Natural Product
Vitexilactone is a diterpenoid derived from the leaves of Vitex negundo L. It exhibits antimicrobial properties against E. coli and has demonstrated the ability to induce apoptosis in cancer cells while inhibiting their cell cycle progression. This compound is particularly valuable for research in cancer biology and microbiology. -
Isoquinoline Alkaloid
Chelidonine hydrochloride is a potent isoquinoline alkaloid derived from Chelidonium majus L. This compound induces G2/M cell cycle arrest and triggers both caspase-dependent and caspase-independent apoptosis, effectively inhibiting stem cell proliferation in Dugesia japonica. Chelidonine hydrochloride demonstrates significant cytotoxic effects against melanoma cell lines, along with notable anticancer and antiviral properties. Its unique biological activities make it a valuable reagent for cancer research and antiviral studies. -
Natural Product
Dehydroeffusol is a phenanthrene derivative isolated from the medicinal herb Juncus effusus. This compound demonstrates potent inhibitory effects on gastric cancer cell proliferation and tumorigenicity by selectively triggering endoplasmic reticulum stress and modulating apoptotic pathways. Notably, Dehydroeffusol exhibits low toxicity, making it a promising candidate for further research in cancer treatment applications. -
Natural Products
Celosin K is a natural product isolated from the seeds of Semen Celosiae, known for its potent inhibitory effects on neuron injury induced by t-BHP. This compound demonstrates significant activity in mitigating oxidative stress and apoptosis, while promoting autophagy. Celosin K is valuable for research applications focused on neuroprotection, oxidative stress, and apoptosis mechanisms. -
Natural Compound
Pancratistatin is an isoquinoline alkaloid derived from the plant Hymenocallis littoralis. It is known to induce apoptosis in human melanoma cells, showcasing its potential as an anticancer agent. This compound is relevant for research applications in various cancer types, including neuroblastoma, leukemia, and breast cancer. -
Natural Products
Shizukaol D is a dimeric sesquiterpene derived from Chloranthus serratus that primarily targets the induction of apoptosis in cellular systems. This compound exhibits significant inhibitory effects on Wnt signaling pathways, making it a valuable tool for research in cancer biology and the study of cell signaling mechanisms. Its unique properties make Shizukaol D an important candidate for investigating therapeutic strategies against Wnt-related diseases. -
Aporphine Alkaloid
Xylopine is an aporphine alkaloid that targets cancer cells with potent cytotoxic activity. It induces oxidative stress, leading to G2/M cell cycle arrest and apoptosis in these cells. Xylopine is primarily utilized in cancer research to explore mechanisms of cell death and to evaluate potential therapeutic strategies. -
Triterpenoid Saponin
Pulchinenoside B is a triterpenoid saponin derived from Pulsatilla chinensis. This compound exhibits various biological activities, including anti-inflammatory and antioxidant effects, and has been studied for its potential therapeutic applications in cancer and cardiovascular diseases. Researchers may find Pulchinenoside B valuable in exploring its mechanistic roles in cellular processes and its potential as a lead compound in drug development. -
Anti-Cancer Agent
Glycoborinine is a natural carbazole alkaloid extracted from Glycosmis pentaphylla, primarily acting as an anti-cancer agent. It induces apoptosis in HepG2 cells through the mitochondrial pathway, showcasing significant potential for cancer research. Additionally, Glycoborinine demonstrates the ability to inhibit HIV replication in cultured cells, highlighting its versatility in various biological applications. -
Flavonoid Antioxidant
Quercetin hydrate is a natural flavonoid with potent antioxidant properties, primarily targeting SIRT1. It acts as a stimulant for recombinant SIRT1 and serves as an inhibitor of phosphoinositide 3-kinases (PI3K), exhibiting IC50 values of 2.4 μM, 3.0 μM, and 5.4 μM for PI3K γ, PI3K δ, and PI3K β, respectively. This compound is widely used in research applications focused on cellular signaling, oxidative stress, and metabolic diseases. -
Phenolic Compound
Hydroxytyrosol is a phenolic compound primarily derived from olive oil, recognized for its antioxidant properties. It mitigates oxidative stress and enhances mitochondrial function, which contributes to its neuroprotective effects. Additionally, Hydroxytyrosol induces apoptosis in cancer cells through the generation of reactive oxygen species (ROS) and exhibits antibacterial and antiviral activities. This compound is applicable in research related to cancer, infectious diseases, inflammation, immunology, and conditions such as diabetes, Alzheimer's disease, and atherosclerosis.
