Fig. 1 · Structure

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L-Stepholidine

Cat. No. A15145 CAS 16562-13-3
L-Stepholidine is a naturally occurring chemical compound found in the herb Stephania intermedia; L-Stepholidine is a dual D2 receptor antagonist and D1 receptor agonist.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
THP-1 IC50 104.58 nM Inhibition of tissue factor procoagulant activity in LPS-stimulated human THP1 cells preincubated for 1 hr before LPS addition measured after 5 hrs [PMID: 23199480]

Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 16562-13-3
Formula C19H21NO4
Molecular Weight 327.37
Synonyms Stepholidine; (-)-Stepholidine; L-SPD
SMILES
COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C(=C(C=C4)O)OC)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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