Catalog No.
Product Name
Application
Product Information
Citations
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Phospholipid
Cardiolipin (Heart, Bovine) sodium is a specific phospholipid found predominantly in mitochondria, extracted from bovine heart tissue. This compound plays a crucial role in maintaining mitochondrial function, regulating cellular metabolism and signaling processes, as well as inducing apoptosis and autophagy. Cardiolipin (Heart, Bovine) sodium is suitable for applications in inflammation, immunology, cardiovascular research, and studies of neurological diseases. Additionally, it can be coated onto microplate wells for use in ELISA assays. -
Natural Product
Daucosterol is a natural sterol compound with demonstrated anti-inflammatory, anticancer, and immunomodulatory properties. It exerts its effects by inducing autophagy through a reactive oxygen species (ROS)-dependent mechanism, inhibiting the proliferation of cancer cells. Additionally, Daucosterol impedes colon cancer growth by promoting apoptosis, suppressing cell migration and invasion, and engaging the caspase signaling pathway, making it a valuable tool for research in cancer biology and therapeutic development. -
Alkaloid Compound
N-Methylnuciferine iodide is an alkaloid compound extracted from Lotus Plumule, known for its potential neuroprotective effects. It has been shown to ameliorate depression-like behavior induced by lipopolysaccharides, making it a valuable tool for studying the mechanisms of inflammation-related mood disorders. This compound may facilitate research into therapeutic strategies for managing depression and related pathologies. -
Active Alkaloid
6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine is an active alkaloid known for its ability to disrupt the structural integrity of cellular organelles, including early endosomes, mitochondria, and autophagosomes. This compound is particularly relevant in the study of neurodegenerative diseases, such as Parkinson's disease, as it has been investigated in patient-derived olfactory cells. Its unique properties make it a valuable tool for researchers exploring cellular function and organelle dynamics in pathological conditions. -
Natural Product
7,8-Didehydrocimigenol is a triterpenoid natural product primarily known for its inhibitory effects on TNF-α-induced VCAM-1 expression. It modulates key signaling pathways by inhibiting NF-kB activity and phosphorylation of ERK1/2 and Akt, while simultaneously increasing PPAR-γ expression. This compound is relevant for research on cardiovascular disorders, including atherosclerosis, offering valuable insights into potential therapeutic approaches. -
Natural Toxin
Biliatresone is a natural toxin derived from Dysphania glomulifera and D. littoralis, functioning primarily as an isoflavonoid within the 1,2-diaryl-2-propenone class. This compound is known to induce extrahepatic biliary atresia in zebrafish models, making it a valuable tool for research into developmental biology and hepatic disorders. Its unique biological activity facilitates studies on gene expression and signaling pathways related to biliary function and development. -
Flavonoid Glycoside
Isorhoifolin is a flavonoid glycoside derived from Hemistepta lyrata, functioning primarily as a bioactive compound with potential protective properties. It has demonstrated an anti-leakage effect, suggesting a role in maintaining cellular integrity. This compound is of interest in studies related to cell protection, oxidative stress, and related therapeutic applications in various biomedical research fields. -
Phenolic Acid
Salvianolic acid Y is a phenolic acid that shares a planar structure with Salvianolic acid B, exhibiting notable protective properties. This compound has demonstrated the ability to mitigate cell injury induced by hydrogen peroxide (H2O2), making it a valuable reagent for studies focused on oxidative stress and cellular protection. Its application in research related to antioxidant activity and cellular responses to oxidative damage enhances its utility in various biochemical investigations. -
Aldehyde Oxidase Substrate
Phthalazine is a substrate for human aldehyde oxidase 1, facilitating the generation of reactive oxygen species (ROS) that contribute to enzyme inactivation. As a nitrogen-containing organic heterocyclic compound, Phthalazine demonstrates significant antitumor activity across various cancer types, including blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer. This reagent is valuable for research focused on cancer biology and the mechanisms underlying oxidative stress in tumorigenesis. -
Quinone
D-α-Tocopherylquinone is a quinone derivative that serves as an oxidation product of α-Tocopherol (vitamin E). It exhibits significant antioxidant and anticoagulant properties, effectively reducing oxidative damage from lipid peroxidation. D-α-Tocopherylquinone interacts with liver cytosolic proteins, notably binding to glutathione-S-transferase (GST), facilitating its transport for metabolism or bile excretion. This compound is valuable for research applications focused on oxidative stress, metabolic pathways, and potential therapeutic interventions in related disorders. -
Phenolic Compound
Brevifolincarboxylic acid is a phenolic compound that targets α-glucosidase, inhibiting its activity with an IC50 value of 323.46 μM. This compound exhibits an inhibitory effect on the aryl hydrocarbon receptor (AhR) and possesses antioxidant properties by scavenging reactive oxygen species (ROS). Additionally, it enhances glucose uptake in myotubes and demonstrates antitumor activity against lung and gastric cancers. Brevifolincarboxylic acid is valuable for research in diabetes and inflammatory diseases. -
Natural Pigment
Pelargonidin 3,5-diglucoside chloride is a natural pigment derived from red fruits and vegetables, primarily known for its role as a reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenger. This compound demonstrates significant biological activity by inhibiting enzymes that contribute to the generation of ROS, RNS, and pro-inflammatory cytokines. Its antioxidant properties make Pelargonidin 3,5-diglucoside chloride valuable for research in oxidative stress, inflammation, and potential therapeutic applications in various health conditions. -
Phenolic Seciridoid
Oleocanthal is a phenolic seciridoid compound primarily known for its inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). This agent exhibits significant anti-inflammatory and neuroprotective properties, along with reducing reactive oxygen species (ROS) and nitric oxide (NO) while upregulating Nrf-2 and HO-1. Oleocanthal also has demonstrated efficacy in reducing amyloid-beta (Aβ) deposition and shows anticancer activity across various cancer types, including colon, breast, liver, and melanoma. Additionally, it displays anti-Leishmania activity against L. major, making it a valuable reagent for Alzheimer’s disease and cancer research. -
Natural Products
Cannflavin C is a natural product isolated from Cannabis sativa, primarily known for its potent antioxidant properties. This compound exhibits significant biological activity that may contribute to cellular protection against oxidative stress. Cannflavin C is of interest in research applications focused on the therapeutic potential of cannabis-derived substances and their role in oxidative damage mitigation. -
Natural Product
Magnoloside F is a natural product derived from Magnolia officinalis, primarily known for its potent antioxidant activity. This compound is of interest in research focused on oxidative stress and its implications in various diseases. Magnoloside F may offer valuable insights into the development of therapeutic strategies targeting oxidative damage. -
Natural Product
Maritimetin is a natural product classified as an aurone, isolated from Coreopsis tinctoria. It exhibits potent antioxidant activity, demonstrated by its strong DPPH radical-scavenging ability with an IC50 value of 4.12 μM. This compound is applicable in research focusing on cardiovascular disease mechanisms and potential therapeutic strategies. -
Triterpenoid
Eburicoic acid is a triterpenoid that exhibits protective effects on the liver by mitigating CCl4-induced hepatic damage through its antioxidant and anti-inflammatory properties. Additionally, it demonstrates antidiabetic and antihyperlipidemic activities, making it a valuable compound for research focused on metabolic disorders and liver health. Its diverse biological activities support its use in studies aimed at understanding complex pathophysiological conditions. -
Flavonoid Glycoside
3'-Methoxy tamarixin is a flavonoid glycoside known for its antioxidant properties. Isolated from the leaves of Cadaba farinosa Forssk, this compound demonstrates significant free radical scavenging activity, with an antioxidant efficacy of 49.1%. It serves as a valuable reagent for research focused on oxidative stress and the protective effects of flavonoids in various biological systems. -
Flavonoid Glycoside
Farobin B is a flavonoid glycoside with potent antioxidant properties, primarily targeting reactive oxygen species. It has demonstrated significant activity in the ORAC assay, indicating its capacity to neutralize oxidative stress. This compound is extracted from the leaves of Fargesia robusta 'Pingwu', making it valuable for research related to oxidative stress, cellular protection, and the biological effects of flavonoids. -
Phenolic Amide Glycoside Compound
N-trans-Feruloyltyramine 4′-O-β-D-glucopyranoside is a phenolic amide glycoside compound sourced from Suaeda japonica. It demonstrates significant antioxidant activity by effectively scavenging DPPH free radicals and reducing reactive oxygen species (ROS) generation induced by hydrogen peroxide in cellular environments. This compound shows potential for research into cardiovascular and neurodegenerative diseases, highlighting its relevance in studies focused on oxidative stress and cellular protection. -
Carcinogenic Natural Compound
1-Hydroxyanthraquinone is a naturally occurring anthraquinone compound known for its oral bioactivity, primarily derived from plants such as Tabebuia avellanedae. This compound has been identified to have carcinogenic properties, making it relevant for studies focusing on cancer research and toxicology. Its biological activities indicate potential insights into the mechanisms of carcinogenesis and the evaluation of plant-derived compounds in cancer biology. -
Tetrasaccharide
Nystose is a tetrasaccharide composed of two fructose units linked through beta (1→2) bonds to the fructosyl portion of sucrose. It demonstrates significant prebiotic properties, along with immunomodulatory and metabolism-regulating activities. Additionally, Nystose has been shown to enhance bone mineralization by activating the Wnt/β-catenin signaling pathway, making it a valuable compound for studies in nutrition and metabolic health. -
Natural Product
Poricoic acid A is a natural product derived from Poria cocos, exhibiting oral bioactivity as an anti-tumor agent. This compound plays a significant role in attenuating renal fibrosis by modulating the Gas6/Axl-NFκB/Nrf2 signaling pathway and activating AMPK while inhibiting Smad3, thus reducing fibroblast activation and abnormal extracellular matrix remodeling. Additionally, Poricoic acid A, in conjunction with Melatonin, has been shown to mitigate oxidative stress and inflammation, improving renal function and decreasing serum creatinine and urea levels in rodent models of ischemia-reperfusion injury. This highlights its potential in renal protection and cancer research applications. -
Bioactive Alkaloid
Aristolochic acid B is a bioactive alkaloid that primarily targets DNA through adduct formation. This compound demonstrates mutagenic properties and poses a higher carcinogenic risk in vivo compared to aristolochic acid I. It is widely utilized in research applications focused on understanding carcinogenesis and the molecular mechanisms of DNA damage. -
Alkaloid
1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole is a carbazole alkaloid that demonstrates significant anti-inflammatory and antimicrobial properties. This compound effectively inhibits the production of pro-inflammatory cytokines, including TNF-α and IL-6. With IC50 values of 10.9 μM against Bacillus cereus and 95 μM against Staphylococcus aureus, it serves as a valuable tool for studies of inflammatory and infectious diseases. As a naturally derived substance from Murraya koenigii, it has potential applications in drug discovery and therapeutic development. -
Natural Product
Luteolin 7-diglucuronide is a natural product derived from the flavonoid classes, primarily found in Aloysia triphylla and Verbena officinalis. This compound exhibits potent antioxidant activity and has been shown to contribute to various biological effects, including anti-inflammatory and neuroprotective properties. Its applications in research encompass studies on plant-derived compounds, pharmacological investigations, and the exploration of its potential health benefits. -
Flavonoid
Isovitexin 2''-O-arabinoside is a flavonoid that primarily targets various biological pathways associated with plant metabolism. This compound demonstrates significant antioxidant activity, making it useful in research related to oxidative stress and cellular signaling. Its applications extend to studies on the health benefits of phytochemicals, as well as investigations into plant physiology and biochemistry. -
Natural Product
7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, also known as 7,8,4'-Trihydroxyisoflavone, is a natural product with potential antioxidant properties. This compound exhibits the ability to scavenge free radicals and may have beneficial effects in various biological systems. Its applications in research include studies on oxidative stress, cellular signaling pathways, and evaluation of its role in disease prevention. -
Prenylated Flavonoid
Parvisoflavone B is a prenylated flavonoid that selectively inhibits protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 42.6 μM and α-glucosidase with an IC50 of 12.19 μM. This compound is derived from the root bark of Erythrina mildbraedii and exhibits significant biological activity relevant to metabolic disorders. Parvisoflavone B is utilized in research exploring mechanisms related to type 2 diabetes and obesity, making it a valuable tool for studying these conditions. -
Anthraquinone
Questin is an anthraquinone compound known for its antibacterial and anticancer properties. It effectively inhibits Cdc25B phosphatase and demonstrates significant antibacterial activity against various bacterial strains, including Vibrio harveyi, Vibrio anguillarum, Vibrio cholerae, and Vibrio parahemolyticus, with minimum inhibitory concentrations (MIC) ranging from 31.25 µg/mL to 125 µg/mL. Additionally, Questin exhibits antiprotozoal effects against the protozoan pathogen Tritrichomonas foetus with an MIC of 12.5 µg/mL and shows potential anticancer activity against lung and colon cancer. -
Natural Compound
3-O-cis-p-Coumaroyl maslinic acid is a natural compound derived from the ethyl acetate extract of Miconia albicans leaves. This compound exhibits a potent inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 0.46 μM, highlighting its significance in metabolic and signaling pathways. Additionally, it demonstrates antimicrobial activity against Gram-positive bacteria and yeasts, making it a valuable candidate for research in pharmacology and microbiology. -
Flavonoid
Rivularin, also known as Skullcapflavone, is a flavonoid derived from Radix scutellariae. It exhibits significant antioxidant properties and has been shown to modulate various signaling pathways, making it a valuable reagent in studies of cellular stress responses and neuroprotection. Its biological activities are of interest in pharmacological research, particularly in the fields of inflammation, cancer, and neurodegenerative diseases. -
Natural Product
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside is a natural product derived from the roots of Polygonaceae species, primarily targeting inflammatory pathways. This compound exhibits significant inhibition of 5-HETE, HHT, and thromboxane B2 formation and is known for its hypotensive, anti-aging, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective properties. Its diverse biological activities make it a valuable reagent for research in cardiovascular health, neurodegenerative diseases, and age-related conditions. -
Natural product
Ginkgo biloba extract primarily targets oxidative stress in neuronal cells, promoting mitochondrial stability and regulating Bcl-2 family proteins to inhibit apoptotic cascades. This natural product demonstrates protective effects against various forms of neuronal damage, including alleviation of testicular injury through SKP2 activation and suppression of Beclin1-independent autophagy. Additionally, Ginkgo biloba extract mitigates neurotoxicity induced by Aβ by disrupting multiple pathways involved in glucose uptake, ROS accumulation, and mitochondrial dysfunction. Its diverse biological activities make it a valuable tool for research into conditions such as Alzheimer's disease, Parkinson's disease, cerebral hypoperfusion, stroke, and traumatic brain injury. -
Flavonoids
3',4'-Dihydroxyflavone is a flavonoid that exhibits notable antiallergic activity, with an IC50 value of 30 μM. This compound serves as a valuable tool for investigating type I allergies and their underlying mechanisms. Its biochemical properties make it suitable for research focused on inflammation and allergic responses. -
Tyrosinase Inhibitor
Kurarinol is a flavanone extracted from the root of Sophora flavescens that functions as a competitive inhibitor of tyrosinase, exhibiting an IC50 value of 0.1 μM against mushroom tyrosinase. This compound is primarily utilized in research focused on skin pigmentation and related disorders, making it valuable in the study of melanogenesis and potential therapeutic applications in hyperpigmentation. -
Phenolic Heterocyclic Compound
Antioxidant agent-21 is a phenolic heterocyclic compound that demonstrates potent antioxidant and anticancer properties. This compound exhibits significant cytotoxic effects against human gastric adenocarcinoma (AGS) and lung cancer (A549) cell lines, highlighting its potential in cancer research. Additionally, Antioxidant agent-21 induces caspase-dependent apoptosis in these cancer cells, making it a valuable tool for studies on cancer therapeutics and apoptosis mechanisms. -
Antitumor Alkaloid
Angustilongine M is a microtubule-targeting antitumor alkaloid that demonstrates significant cytotoxicity with an IC50 of 0.2 μM against HT-29 colorectal cancer cells. This compound induces G0/G1 cell cycle arrest and promotes mitochondrial apoptosis through enhanced tubulin polymerization. Angustilongine M is valuable for research applications related to colorectal cancer and other solid tumors. -
natural product
Diselaginellin B is a natural product derived from Selaginella pulvinata, known for its potent anti-proliferative effects. It induces apoptosis and demonstrates significant antimetastatic activity in human hepatocellular carcinoma cells. This compound is valuable for research applications focusing on cancer biology and therapeutic development. -
Alkaloid
Cinchonine hydrochloride is a natural alkaloid derived from Cinchona bark, primarily known for its antimalarial activity. This compound effectively activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells, making it a valuable tool in cancer research. Its unique mechanism and biological activity provide insights into therapeutic strategies targeting liver malignancies and highlight its potential in studying ER stress responses. -
Steroidal Alkaloid
Solasodine hydrochloride is a steroidal alkaloid derived from plants in the Solanaceae family. It exerts its biological activity by inducing apoptosis through the inhibition of the p53-MDM2 complex, as well as modulating the expression of p21Waf1/Cip1 and Bcl-2 proteins. This compound showcases a variety of therapeutic potentials, including neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic, and anti-inflammatory effects, making it suitable for diverse research applications in pharmacology and toxicology. -
Natural Sunscreen
Gadusol is a natural sunscreen synthesized by the mother during oogenesis, providing vital protection against UVB-induced DNA damage in early developmental stages of fish. By preventing cellular stress and apoptosis, Gadusol serves as a primary sunscreen mechanism stored in eggs. This compound does not exhibit antioxidant properties in zebrafish embryos, making it particularly relevant for studies in topical photoprotective cosmetics. Its unique protective qualities enhance research into natural photoprotection strategies. -
Alkaloid
Harmalol is a β-carbazine alkaloid that exhibits significant anticancer activity by targeting nucleic acids. It binds to both natural and synthetic DNA and RNA with varying motifs, facilitating its interactions. Harmalol also induces apoptosis in human hepatoma cells in vitro, making it a valuable reagent for cancer research and studies involving nucleic acid interactions. -
Natural Product
Barbigerone, a natural product derived from Amomum nilgiricum, is characterized by its unique chemical structure. This compound exhibits significant biological activity, serving as a valuable resource for research in various fields, including pharmacology and biochemistry. Its potential applications include the exploration of therapeutic properties and interactions within biological systems, making it an important tool for studying natural bioactive compounds. -
Alkaloid
Pipermethystine is an alkaloid isolated from the Kava plant, known to modulate cellular energy dynamics. It decreases ATP levels and mitochondrial membrane potential in HepG2 cells, ultimately leading to the induction of apoptosis. This compound is of interest for research focused on cancer biology and mitochondrial function. -
Flavonoids
3′-Hydroxyflavanone is a cyclized flavanone that primarily targets flavonoid pathways. It has been shown to induce apoptosis in HeLa cells and exhibits significant antitumor activity. This compound is valuable for research applications focused on cancer biology and the therapeutic potential of flavonoids in tumor suppression. -
Natural Product
Aloin (mixture of A&B) is an orally active anthraquinone derivative derived from Aloe vera, known for its extensive biological activities. It demonstrates neuroprotective, anti-inflammatory, antioxidant, antibacterial, antifungal, antiviral, and antitumor properties. Aloin inhibits key enzymes such as Clostridium histolyticum collagenase, granulocyte matrix metalloproteinases, and the human 20S proteasome, while modulating important pathways including Nrf2/HO-1 and TGF-β/Smad2/3. Its application extends to research involving chronic ulcers, burns, wounds, inflammatory and degenerative disorders, asthma, and neuroblastoma. -
Flavonoid Glycoside
Luteolin-7-rutinoside is a flavonoid glycoside known for its anti-arthritic and antifungal properties. This compound can be utilized in combination therapies targeting fungal arthritis, particularly in cases associated with Candida albicans infection. Its diverse biological activities make it a valuable tool for research in inflammatory diseases and mycological studies. -
Natural Alkaloid
Isoharringtonine is a natural alkaloid derived from Cephalotaxus koreana Nakai. This compound demonstrates significant inhibitory effects on cancer cell proliferation and migration, while also promoting apoptosis in cancer cells. Isoharringtonine is useful in cancer research, particularly in studies exploring therapeutic strategies and mechanisms of action against various malignancies. -
Alkaloid
Mycoleptodiscin A is a cytotoxic indole alkaloid derived from fungi, primarily known for its pro-apoptotic activity and ability to disrupt cell cycle progression. It is utilized in research to investigate mechanisms of apoptosis and assess potential therapeutic applications in cancer treatment. This compound serves as a valuable tool for studying the biological effects of alkaloids on cellular processes.
