Angustilongine M is a microtubule-targeting antitumor alkaloid that demonstrates significant cytotoxicity with an IC50 of 0.2 μM against HT-29 colorectal cancer cells. This compound induces G0/G1 cell cycle arrest and promotes mitochondrial apoptosis through enhanced tubulin polymerization. Angustilongine M is valuable for research applications related to colorectal cancer and other solid tumors.
Angustilongine M is a microtubule-targeting antitumor alkaloid that demonstrates significant cytotoxicity with an IC50 of 0.2 μM against HT-29 colorectal cancer cells. This compound induces G0/G1 cell cycle arrest and promotes mitochondrial apoptosis through enhanced tubulin polymerization. Angustilongine M is valuable for research applications related to colorectal cancer and other solid tumors.
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