Fig. 1 · Structure

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6-Benzoylheteratisine

Aconitum Alkaloid

6-Benzoylheteratisine acts as an antagonist of tetrodotoxin and targets sodium channels, demonstrating potential neuroprotective activity. It effectively inhibits the influx of sodium ([Na+]i) and calcium ([Ca2+]i) ions, as well as the release of glutamate, making it relevant for the study of excitatory neurotransmission. Additionally, 6-Benzoylheteratisine has shown inhibitory effects on neuronal activity associated with epileptiform burst discharge, suggesting its utility in neurological research and potential therapeutic applications in epilepsy.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 99759-48-5
Applications Aconitum Alkaloid
Formula C29H37NO6
Molecular Weight 495.61
SMILES
CO[C@@H]1[C@]23[C@]4([H])[C@@H]([C@@]([C@@]5([C@]6([H])[C@@]3([H])C[C@H](CC5)OC6=O)O)([H])[C@@]2([H])N(C[C@@]4(CC1)C)CC)OC(C7=CC=CC=C7)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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