Other inhibitors

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  1. Sophocarpine could reverse isoprenaline-induced arrhythmia and inhibit I(Na), I(CaL), and I(Kr) currents. The electrophysiological effects of sophocarpine are similar to those of amiodarone, which might be regarded as a prospective antiarrhythmic agent.
  2. Spectinomycin is an antibiotic useful for the treatment of the bacterial infection, gonorrhea.
  3. Stigmasterol, which is readily obtainable from soybean oil, can be transformed easily to progesterone and to other hormones.
  4. dipeptidase inhibitor

    Cilastatin is a dipeptidase inhibitor that specifically inhibits DPEP1 (dehydrodipeptidase I), a renal membrane-bound glycoprotein involved in the hydrolytic metabolism of penem and carbapenem ??-lactam antibiotics.
  5. Tangeretin (Tangeritin) is an O-polymethoxylated flavone that is found in tangerine and other citrus peels. Tangeretin (Tangeritin) strengthens the cell wall and acts as a plant's defensive mechanism against disease-causing pathogens. Tangeretin (Tangeritin) also shows enormous potential as an anti cancer agent.
  6. Taurine is an organic acid widely distributed in animal tissues. It is a major constituent of bile and can be found in the large intestine and accounts for approximately 0.1% of total human body weight.
  7. Isoindigotin is a potential antileukemic agent.
  8. Tenoxicam belongs to the class of NSAIDs known as oxicams.
  9. Terbinafine HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition.
  10. Indacaterol is an ultra-long-acting beta-adrenoceptor agonist.
  11. Tranilast is an antiallergic drug. It reduces collagen synthesis in fibroblasts and inhibits growth of neurofibroma cells, also inhibits the production of interleukin-6 in endothelial cells.
  12. Troxerutin(Trihydroxyethylrutin) is a flavonol, a type of flavonoid. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the japanese pagoda tree.It is used as a vasoprotective.
  13. Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas.
  14. Xanthone is an organic compound. It can be prepared by the heating of phenyl salicylate. In 1939, xanthone was introduced as an insecticide and it currently finds uses as ovicide for codling moth eggs and as a larvicide. Xanthone is also used in the preparation of xanthydrol, which is used in the determination of urea levels in the blood
  15. Yohimbine hydrochloride (Antagonil) is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively)
  16. HPPD inhibitor

    Nitrisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase).
  17. Folinic Acid Calcium Salt (Leucovorin) is the active form of the B complex vitamin Folate is used as an antidote to cancer treatment drugs (i.e. methotrexate) to reduce toxicity of residual drugs.
  18. FTO inhibitor

    FB23 is a potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO (fat mass and obesity associated protein).
  19. hypoglycemic agent

    Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity.
  20. Methyl 13-cis-4-Oxoretinoate is a bioactive chemical.
  21. transcriptional inhibitor of G0/G1 switch 2

    NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease.
  22. U 19963 (1,3-Bis(4-fluorophenyl)thiourea) is a bioactive compound.
  23. NSC 191412 (1-(4-Fluorophenyl)-3-phenylthiourea) is an active compound.
  24. Adipamidoxime (NSC 70868) is a new bioactive compoud.
  25. oxyhaemoglobin stabilizer

    Velaresol, also known as BW12C or BW12C79, is a oxyhaemoglobin stabilizer.
  26. anticonvulsant/antiepileptic agent

    Lvguidingan (Anticonvulsant 7903, 3,4-dichlorophenyl propenylisobutylamide) is an anticonvulsant/antiepileptic agent. Lvguidingan (Anticonvulsant 7903) is found to be able to increase the concentration of 5-HT and 5-HIAA in mice brain.
  27. Tri-Salicylic Acid (Trisalicylic Acid), a product of the thermal decomposition of aspirin, is a biochemical for proteomics research.
  28. chemical cyclophilin A inhibitor

    TMN355 is a potent chemical cyclophilin A inhibitor and reduces foam cell formation and cytokine secretion. TMN355 is used for atherosclerosis.
  29. liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist

    ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist with an IC50 of 3.7 ?M.

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