Catalog No.
Product Name
Application
Product Information
Citations
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immunomodulator
Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity. - Substituted piperidines-1 is a compound that can promote the release of growth hormone in humans and animals.
- Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors.
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CNT2 Inhibitor
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. -
ocular β-blocker
(E)-Alprenoxime is the isomer of the Alprenoxime. Alprenoxime is a site-activated ocular β-blocker. - Ombrabulin is a synthetic water-soluble analogue of combretastatin A4, derived from the South African willow bush (Combretum caffrum), with potential vascular-disrupting and antineoplastic activities.
- Teglarinad chloride, also known as GMX1777, is a water-soluble prodrug of a cyanoguanidine compound with potential antineoplastic activity. In vivo, teglarinad chloride is rapidly converted into active drug through hydrolytic cleavage of a carbonate ester bond.
- Pyronaridine Tetraphosphate is a common antimalarial agent that has been found to enhance the antitumor activity of doxorubicin against multidrug-resistant cancers K562/A02 and MCF-7/ADR.
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squalene epoxidase inhibitor
FR194738 free base is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. -
synthesized plant gowth regulator
Prohydrojasmon racemate is a synthesized plant gowth regulator. -
Neutrophil elastase inhibitor
Freselestat is a potent neutrophil elastase inhibitor. Freselestat reduces inflammatory mediators during simulated extracorporeal circulation. ONO-6818 significantly reduced interleukin 8 and C5b-9 production. ONO-6818 did not modulate changes of CD11b and L-selectin during recirculation. -
Histone-H2A peptide
Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. - Prochloraz manganese is a sterol C-14 demethylation inhibitor which impairs biosynthesis of ergosterol, an essential compound for the stability and functioning of lipoprotein membranes
- Ibutamoren, also known as MK-677 (L-163,191), is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin.
- Cardiolipin is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.
- Ceftobiprole medocaril is a fifth-generation[2] cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus, penicillin-resistant Streptococcus pneumoniae, Pseudomonas aeruginosa, and enterococci.
- D2PM (hydrochloride) is a psychoactive designer drug that has recently been demonstrated to have toxic effects in humans.
- Lomifylline is a methylxanthine analogue which induces Ca2+-release from intracellular stores via the ryanodine receptor.
- Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.
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MC4 antagonist
SNT207858 is a 22 nM MC4 antagonist with a 170-fold selectivity vs. MC3 and a 40-fold selectivity versus MC5. - 4-Epi Minocycline is an impurity of Minocyclin, a second generation tetracycline antibiotic.
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SCD1 inhibitor
stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; induces ER stress, attenuates protein synthesis and induces apoptosis in hPSCs. Prevents teratoma formation in immunocompromised mice. - Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of ??-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
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cytoplasmic dynein antagonist
Ciliobrevin D is the first specific small molecule antagonist of cytoplasmic dynein -
glycolate oxidase inhibitor
Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV. -
AKR1C3 inhibitor
AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM. - GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4?CNKX2-5 transcriptional synergy with an IC50 of 3 μM.
- Benzophenonetetracarboxylic acid (3,3',4,4'-Benzophenonetetracarboxylic acid) is particularly useful in the preparation of high performance polyimides and also useful as curing agents for epoxy resins.
- Trimipramine (Surmontil, Rhotrimine, Stangyl) is a tricyclic antidepressant (TCA). It has antidepressant, anxiolytic, antipsychotic, sedative, and analgesic effects
