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Biological Activity
Teglarinad chloride, also known as GMX1777, is a water-soluble prodrug of a cyanoguanidine compound with potential antineoplastic activity. In vivo, teglarinad chloride is rapidly converted into active drug through hydrolytic cleavage of a carbonate ester bond.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.87 mL | 74.34 mL | 148.67 mL |
| 0.5 mM | 2.97 mL | 14.87 mL | 29.73 mL |
| 1 mM | 1.49 mL | 7.43 mL | 14.87 mL |
| 5 mM | 0.3 mL | 1.49 mL | 2.97 mL |
*The above data is based on the productmolecular weight 672.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12669 |
|---|---|
| CAS No. | 432037-57-5 |
| Formula | C30H43ClN5O8.Cl |
| M. Wt | 672.61 |
| Purity | >98% |
| Synonyms | GMX1777,GMX 1777,GMX-1777 |
| SMILES | COCCOCCOCCOCCOC(=O)OC[N+]1=CC=C(C=C1)NC(=NCCCCCCOC2=CC=C(C=C2)Cl)NC#N.[Cl-] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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