Catalog No.
Product Name
Application
Product Information
Citations
-
hypoglycemic agent
Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity. -
active oxygen formation inducer
Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes. -
transcriptional inhibitor of G0/G1 switch 2
NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease. -
anticonvulsant/antiepileptic agent
Lvguidingan (Anticonvulsant 7903, 3,4-dichlorophenyl propenylisobutylamide) is an anticonvulsant/antiepileptic agent. Lvguidingan (Anticonvulsant 7903) is found to be able to increase the concentration of 5-HT and 5-HIAA in mice brain. - Tri-Salicylic Acid (Trisalicylic Acid), a product of the thermal decomposition of aspirin, is a biochemical for proteomics research.
-
Biochemical Assay Reagent
DCIP sodium is a redox indicator utilized primarily in biochemical assays. Its distinctive blue coloration shifts according to the oxidation state of the analyte, making it effective in measuring enzymatic activities, including succinate dehydrogenase. Additionally, it serves as a valuable reagent in protein quantification methods, such as the Lowry assay, facilitating accurate analytical results in various research applications. -
Biochemical Assay Reagent
Bathocuproine disulfonate disodium (BCS) is a highly sensitive colorimetric reagent utilized for the detection of copper ions in biochemical assays. This compound exhibits a bright yellow color and possesses strong absorbance at specific wavelengths, enabling the quantification of trace levels of copper. BCS is instrumental in studying copper's biological roles, as well as in environmental monitoring and water quality testing, where its sensitivity allows for the identification of copper pollution, even at minimal concentrations. Accurate measurement of copper is essential for understanding its physiological effects and ecological impacts. -
Cholesterol-removing Agent
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent. Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis. Methyl-β-cyclodextrin blocks cell migrasome formation. -
Globular Protein
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications. -
Skin Depigmenting Agent
Monobenzone is a potent skin depigmenting agent that primarily targets the enzyme ribonucleotide reductase (RNR) by inhibiting its regulatory subunit, RRM2. It effectively induces depigmentation, making it a valuable compound in vitiligo research. Additionally, Monobenzone demonstrates significant anti-leukemic properties, inhibiting the proliferation and DNA synthesis of acute myeloid leukemia (AML) cells, and promoting cell cycle arrest and apoptosis. These dual functionalities position Monobenzone as a critical reagent in both dermatological and oncology studies. -
Excipient
SBE-β-CD is a sulfobutylether derivative of β-cyclodextrin primarily utilized as an excipient in pharmaceutical formulations. It enhances the solubility of poorly soluble compounds, thereby improving their bioavailability. SBE-β-CD is valuable in drug development, particularly for improving the delivery of hydrophobic agents in various therapeutic applications. -
Biochemical Assay Reagent
(±)-myo-Inositol-1-phosphate is a biochemical assay reagent known for its role as a phosphoinositide signaling molecule. This compound is involved in cellular processes such as insulin signaling, cell proliferation, and regulation of ion channels. It is utilized in various research applications, including studies on diabetes, neurodegenerative diseases, and cell signaling pathways. -
Iron Colorimetric Reagent
Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent primarily used for the detection of iron, exhibiting an optimal absorbance at 535 nm for iron complexes. This reagent facilitates the determination of iron concentrations in aqueous solutions without the necessity for extraction solvents. Additionally, BPS is utilized as a precursor in the synthesis of specialized complexes, including Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) and ruthenium(II) tris(bathophenanthrolinedisulfonate), and plays a role in catalyst systems for the oxidation of 2-hexanol by forming stable water-soluble complexes with palladium. -
Colorimetric Reagent
2-Thiobarbituric acid is a colorimetric reagent primarily used for the quantitative detection of malondialdehyde (MDA), a key biomarker of lipid peroxidation. It forms a chromogenic complex with MDA that can be measured at 532 nm. This reagent is essential for studies investigating oxidative stress and lipid peroxidation in various biological samples. -
Biochemical Reagent
Copper sulfate pentahydrate is a biochemical reagent commonly used in cell culture applications. This compound demonstrates the ability to reduce the production of reactive oxygen species (ROS) and downregulate the expression of MyD88 and c-Rel genes. Additionally, copper sulfate pentahydrate affects enzymatic activities by decreasing T-superoxide dismutase (T-SOD), catalase (CAT), and glutathione (GSH) levels, while promoting the activities of caspase-3, -8, and -9. Its cytotoxic effects make it valuable for studies involving cellular apoptosis and oxidative stress. -
Drug Impurity
Methotrexate impurity 4 is a known impurity associated with Methotrexate, primarily classified as a drug impurity. This compound is utilized in research to assess drug purity and stability, as well as to study potential side effects and metabolic pathways related to Methotrexate. Its characterization is critical for quality control and regulatory compliance in pharmaceutical formulations. -
Biochemical Reagent
Ethyl methanesulfonate is a potent alkylating agent known for its ability to induce DNA damage. By modifying DNA structure through alkylation, it triggers apoptosis and can lead to mutations and cell death. This compound is extensively utilized in genetic toxicology research to facilitate the study of gene function, mechanisms of genetic diseases, and the impacts of environmental mutagens on cellular systems. Additionally, it has been shown to induce tumors in kidney and nervous system tissues, highlighting its relevance in cancer research. -
Biochemical Assay Reagent
Rhodamine B isothiocyanate (RBITC) is a reactive fluorescent dye widely used for covalent labeling of biomolecules in imaging and analytical applications. The isothiocyanate functional group readily reacts with primary amines on proteins, peptides, and other biomolecules to form stable thiourea linkages, enabling durable fluorescent tagging. RBITC emits bright orange-red fluorescence upon green light excitation, providing strong signal intensity and excellent photostability for visualization in complex biological systems. Owing to its high sensitivity, chemical stability, and compatibility with diverse assay conditions, RBITC is extensively utilized in cell biology, immunology, neurobiology, and fluorescence microscopy studies for tracking molecular localization and dynamics. -
Biochemical Reagent
Mutanolysin is a muralytic enzyme that acts as a bacteriolytic agent, targeting bacterial cell walls. It exhibits significant protective effects against hepatic injury and has been shown to decrease TNF-α production in isolated Kupffer cells stimulated with peptidoglycan-polysaccharide. Additionally, Mutanolysin mitigates the elevation of plasma anti-peptidoglycan antibodies and TNF-α levels in rat models, making it a valuable reagent for studying inflammation and bacterial infections. Its applications extend to biochemical research, particularly in exploring immune responses and hepatic health. -
Ester Product
Dodecane is an aliphatic hydrocarbon classified as an ester product. It has been demonstrated to induce elevated levels of TNF-α expression, a key cytokine involved in inflammatory responses, and can also lead to increased transepidermal water loss (TEWL), which is critical for studies on skin barrier function. This compound is relevant for research applications in inflammation, dermatological studies, and understanding skin permeability. -
Olanzapine Impurity
Olanzapine ketolactam is an impurity associated with Olanzapine, a selectively acting monoaminergic antagonist. This compound may be utilized in chemical research to study the structural and functional properties of Olanzapine and its metabolites. Its presence could provide insights into the pharmacological profiles and safety assessments of olanzapine formulations. -
Impurity
Gefitinib impurity 2 is an impurity of the EGFR tyrosine kinase inhibitor, Gefitinib. While Gefitinib exhibits potent and selective inhibition of EGFR with an IC50 of 33 nM, this impurity may be relevant for studies focused on the characterization and validation of Gefitinib-related compounds. Research applications primarily include analytical chemistry and quality control in the synthesis of Gefitinib. Additionally, the impurity may provide insights into the pharmacological behavior and metabolic pathway analysis of EGFR inhibitors. -
Biochemical Assay Reagent
Manganese chloride (tetrahydrate) is a biochemical assay reagent that plays a critical role in regulating enzyme activities, particularly histone acetyltransferase (HAT) and histone deacetylase (HDAC), influencing gene expression. This compound exhibits biological activities including neurotoxicity, embryotoxicity, and reproductive toxicity. It is predominantly utilized in research related to neurodegenerative diseases and toxicology, providing valuable insights into cellular and molecular mechanisms. -
Drug Intermediate
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide serves as an essential drug intermediate in the synthesis of diverse bioactive molecules. This compound's structural framework enables exploration in medicinal chemistry and drug development, facilitating the creation of therapeutically relevant agents. Researchers utilize this intermediate to optimize pharmacological properties and enhance biological activity across various applications. -
Biochemical Reagent
1-Pyrenedecanoic acid is a biochemical reagent primarily utilized to assess membrane fluidity. This compound intercalates into lipid bilayers, enabling the study of membrane dynamics and properties. It is valuable in research focusing on cellular membrane behavior and related physiological processes. -
Biochemical Reagent
Xanthomegnin is a yellow pigment with biochemical properties isolated from the fungus Trichophyton megnini. This compound is widely utilized in various research applications, particularly in the study of fungal metabolism and pigment biosynthesis. Its unique colorimetric characteristics make it a valuable reagent in biochemical assays and analytical studies involving enzymatic activity and compound interactions within biological systems. -
Biochemical Reagent
Zapotin is a polymethoxyflavone that functions as a biochemical reagent, exhibiting multiple biological activities. It demonstrates significant antidepressant, anticancer, antifungal, and antioxidant properties, making it a candidate for chemopreventive and chemotherapeutic applications. Studies show that Zapotin effectively reduces large aberrant crypt foci in CF-1 mouse models and inhibits autophagosome formation. Additionally, it displays inhibitory activity in mouse mammary organ culture, with an IC50 value of 50 µg/mL. -
Drug Intermediate
Camphorsulfonate sodium functions as an organic synthesis intermediate with significant utility in the development of derivatives exhibiting succinate dehydrogenase (SDH) inhibitory activity through scaffold hopping. Additionally, it serves as an organocatalyst, effectively modulating the porosity of graphene films as a pore-forming additive. This compound is valuable in research applications focused on binder-free porous graphene films and fungicide development. -
Drug Impurity
Ramipril diketopiperazine is a chemical impurity associated with the ACE inhibitor Ramipril. It is important for analytical studies and quality control in pharmaceutical research, particularly in the evaluation of drug formulation and stability. The presence of this impurity can influence the pharmacokinetics and safety profile of Ramipril, making it crucial for researchers analyzing drug metabolism and efficacy. -
Ramiprilat Impurity
Ramiprilat diketopiperazine, also known as Impurity K of Ramiprilat, serves as a significant impurity within the context of pharmaceutical research. Ramiprilat, an active metabolite of Ramipril, functions primarily as a potent angiotensin-converting enzyme (ACE) inhibitor. This compound is important for studying the effects and stability of Ramiprilat in various formulations and can be useful in analytical chemistry to ensure the purity of ACE inhibitors in development. -
Biochemical Assay Reagents
3-Azidopropanol is an azide-containing alcohol utilized as a substrate in click chemistry reactions. It facilitates Cu-catalyzed addition reactions with propargyl alcohol, making it a valuable tool in bioconjugation and labeling strategies. This reagent is essential for applications in biochemical assays, enabling the study of biomolecular interactions and the development of targeted therapeutics. -
MOF
Antibacterial agent 18 is a multi-arm aggregation-induced emission (AIE) molecule targeting bacterial cell walls. This compound exhibits potent antibacterial activity against both Gram-positive and Gram-negative bacteria by disrupting the synthesis of critical cell wall components, effectively inhibiting bacterial growth or inducing cell death. It is suitable for research applications focused on understanding bacterial resistance mechanisms and developing novel antibacterial therapies. -
Biochemical Reagent
Methyl 2-amino-5-bromobenzoate is a biochemical reagent that serves as a precursor for synthesizing 2-benzamidobenzoic acid, a recognized FabH inhibitor. Additionally, its derivatives have demonstrated the ability to inhibit PqsD, which is part of the quorum sensing (QS) system in Pseudomonas aeruginosa. This compound is valuable for research involving antibiotic development and investigation of bacterial communication pathways. -
Biochemical Reagent
Silver(I) sulfide is a biochemical reagent with prominent antibacterial properties. It exhibits effective antimicrobial activity against a range of resistant bacteria, including both Gram-positive and Gram-negative strains. This compound is valuable for research into bacterial infections, particularly those caused by pathogens such as *Staphylococcus aureus*, *Streptococcus agalactiae*, *Escherichia coli*, and *Pseudomonas* species. -
Biochemical Assay Reagent Control
Calcium hydroxide, a dihydroxy form of calcium, serves as an important biochemical assay reagent control. This compound is utilized for its buffering capacity and as a pH modifier in various biological experiments. Calcium hydroxide is critical for maintaining optimal conditions in enzymatic assays and other biochemical applications, contributing to accurate and reproducible results in research settings. -
Biochemical Assay Reagent
L-Sorbitol is a six-carbon sugar alcohol that serves as a versatile biochemical assay reagent. It is commonly utilized in various biochemical experiments and can influence osmotic pressure, making it valuable in studies related to cell biology and metabolism. Additionally, L-Sorbitol can function as a substrate in enzymatic assays and as a cryoprotectant in cell preservation applications. Its role in cellular processes positions it as an essential tool in life science research. -
Biochemical Assay Reagents
Agar is a gelatinous polysaccharide derived from the cell walls of red algae species, including Gelidium and Gracilaria. Its primary mechanism involves forming reversible physical gels through hydrogen bonding, making it an essential medium for cell culture applications. Agar is widely utilized in microbiological assays, plant tissue culture, and various biochemical applications, offering a stable environment for the growth and maintenance of microorganisms and cells in research settings. -
Biochemical Reagent
Sodium tetraborate decahydrate is a versatile biochemical reagent with multiple applications in research. It enhances the activity of antioxidant enzymes such as catalase and superoxide dismutase, contributing to its neuroprotective effects against chromium-induced toxicity. Additionally, sodium tetraborate decahydrate exhibits antibacterial properties by reducing hydrogen sulfide levels and inhibiting the growth of sulfate-reducing bacteria in swine manure. This compound also acts as a triglyceride transesterification catalyst and a flame suppressant for wood cellulose, making it valuable in various scientific investigations. -
Biochemical Reagents
N-Chlorosuccinimide is a potent chlorinating agent primarily used as a biochemical reagent for aliphatic and aromatic chlorination reactions. This versatile compound enhances microbial activity and has been shown to augment the antimicrobial effects of Benzalkonium chloride against biofilm-forming Pseudomonas aeruginosa. Its applications extend to various synthetic and analytical processes, making it a valuable tool in chemical research. -
Biochemical Assay Reagent
Silver nitrite is an inorganic compound with the formula AgNO2, serving as a biochemical assay reagent. It exhibits antimicrobial properties by inhibiting cell division and bacterial growth through interference with protein synthesis. This compound is useful in various research applications, including studies on cellular processes and the investigation of antibacterial mechanisms. -
Biochemical Assay Reagent
Octanohydroxamic acid is a biochemical assay reagent primarily utilized for its role as an extractant for alkaloids in pharmaceutical and natural product research. This compound may also inhibit specific enzymes, including hydroxamate hydrolases, making it valuable for studies related to enzyme activity and inhibition mechanisms. Its versatile applications contribute to the understanding of biochemical pathways and the development of novel therapeutic agents. -
Biochemical Assay Reagent
Protamine from salmon is a biochemical assay reagent that serves as an antagonist to heparin, effectively neutralizing its anticoagulant effects. This compound exhibits antioxidant and antimicrobial properties, making it valuable in various research applications. It is particularly useful in studies involving antithrombin complexes, especially in canine samples pretreated with heparin in vitro. -
Drug Intermediate
3,3-Dimethylacrylic acid is a key intermediate in the synthesis of various pharmaceutical compounds. This small molecule is utilized in the development of drugs, particularly in the creation of polymers and other materials due to its unique structural features. Its versatility as a building block makes it an important reagent in chemical research and drug development applications.
