Catalog No.
Product Name
Application
Product Information
Citations
- Tranilast is an antiallergic drug. It reduces collagen synthesis in fibroblasts and inhibits growth of neurofibroma cells, also inhibits the production of interleukin-6 in endothelial cells.
- Troxerutin(Trihydroxyethylrutin) is a flavonol, a type of flavonoid. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the japanese pagoda tree.It is used as a vasoprotective.
- Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas.
- Xanthone is an organic compound. It can be prepared by the heating of phenyl salicylate. In 1939, xanthone was introduced as an insecticide and it currently finds uses as ovicide for codling moth eggs and as a larvicide. Xanthone is also used in the preparation of xanthydrol, which is used in the determination of urea levels in the blood
- Yohimbine hydrochloride (Antagonil) is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively)
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HPPD inhibitor
Nitrisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase). - Folinic Acid Calcium Salt (Leucovorin) is the active form of the B complex vitamin Folate is used as an antidote to cancer treatment drugs (i.e. methotrexate) to reduce toxicity of residual drugs.
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Drug Impurity
Methotrexate impurity 4 is a known impurity associated with Methotrexate, primarily classified as a drug impurity. This compound is utilized in research to assess drug purity and stability, as well as to study potential side effects and metabolic pathways related to Methotrexate. Its characterization is critical for quality control and regulatory compliance in pharmaceutical formulations. -
Biochemical Reagent
Ethyl methanesulfonate is a potent alkylating agent known for its ability to induce DNA damage. By modifying DNA structure through alkylation, it triggers apoptosis and can lead to mutations and cell death. This compound is extensively utilized in genetic toxicology research to facilitate the study of gene function, mechanisms of genetic diseases, and the impacts of environmental mutagens on cellular systems. Additionally, it has been shown to induce tumors in kidney and nervous system tissues, highlighting its relevance in cancer research. -
Phosphoramidite Monomer
2'-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer designed for oligonucleotide synthesis. This compound incorporates a 2'-O-methyl modification and a benzoyl protective group, enhancing the stability and efficiency of synthesized oligonucleotides. It is highly relevant in research applications involving gene expression studies, antisense oligonucleotide design, and RNA interference. -
Phosphoramidite Monomer
DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer utilized in the synthesis of DNA and nucleic acid derivatives. It serves as a key building block for creating oligonucleotides, enabling researchers to investigate genetic sequences and design nucleic acid-based applications. This reagent is essential for studies in genomics, molecular biology, and various therapeutic research areas. -
Biochemical Assay Reagent
DMT-dA(bz) Phosphoramidite is a key reagent utilized in the chemical synthesis of DNA. This phosphoramidite derivative features a dimethoxytrityl (DMT) group, which enhances the protection of the nucleobase during oligonucleotide assembly. It plays a crucial role in facilitating the incorporation of 2'-deoxyadenosine with a benzoyl protecting group, making it valuable for applications in molecular biology, genetics, and biochemistry research. -
Biochemical Assay Reagent
DMT-dT Phosphoramidite is a key reagent used in the chemical synthesis of DNA. It functions as a phosphoramidite nucleotide that facilitates the incorporation of deoxythymidine into oligomeric sequences during solid-phase synthesis. This compound is essential for applications in genetic research, molecular diagnostics, and the development of nucleic acid-based therapies. -
Phosphoramidite
Bz-rA Phosphoramidite is a phosphoramidite that features a 5' DMT and adenosine (A) with benzoyl (Bz) base protection. This reagent is specifically designed for the efficient synthesis of oligonucleotides. Its reliable incorporation of benzoyl-protected adenosine monomers facilitates studies in gene expression, molecular biology, and nucleic acid research. -
Phosphoramidite Derivative
DMT-dC(ac) Phosphoramidite is a phosphoramidite derivative primarily utilized in oligonucleotide synthesis. This compound serves as a protected form of deoxycytidine and plays a critical role in facilitating the incorporation of dC residues during the assembly of nucleic acid strands. Its use in solid-phase synthesis enables researchers to create diverse oligonucleotides for applications in molecular biology and genetic research. -
Phosphoramidite Monomer
DMT-2'-F-Bz-dA is a phosphoramidite monomer utilized in the synthesis of oligonucleotides. This compound features a 2'-fluoro substitution, which enhances the stability and specificity of nucleic acid interactions. It is particularly valuable in the design of modified oligonucleotides for applications in gene editing, antisense technologies, and molecular diagnostics. -
Phosphoramidites
2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite reagent essential for oligonucleotide synthesis. Its primary mechanism involves the formation of phosphodiester linkages, facilitating the assembly of nucleic acid sequences. This compound is widely utilized in molecular biology for the development of DNA and RNA oligonucleotides for research applications, including gene expression studies and therapeutic development. -
Phosphoramidite
Dmt-2'-f-dc(ac) amidite is a phosphoramidite used in the synthesis of cyclic purine dinucleotides. This compound facilitates the incorporation of modified nucleotides in oligonucleotide synthesis, allowing for enhanced stability and altered biological activity in nucleic acid studies. Its applications extend to research in nucleic acid therapeutics, gene regulation, and other molecular biology fields. -
Olanzapine Impurity
Olanzapine ketolactam is an impurity associated with Olanzapine, a selectively acting monoaminergic antagonist. This compound may be utilized in chemical research to study the structural and functional properties of Olanzapine and its metabolites. Its presence could provide insights into the pharmacological profiles and safety assessments of olanzapine formulations. -
Cetirizine Impurity
Cetirizine methyl ester is a known impurity of Cetirizine, a second-generation antihistamine that functions as a selective, orally active, and long-lasting antagonist of the histamine H1 receptor. This compound serves as an important analytical reference for the study of Cetirizine's purity and quality control processes. Its relevance in biochemical research and pharmaceutical development makes it a valuable tool for investigating the pharmacological profile of antihistamines. -
Biochemical Reagent
L-Ascorbic acid calcium dihydrate functions primarily as a biochemical reagent. This compound serves as a stable source of Vitamin C, acting as a potent antioxidant that scavenges free radicals and reduces oxidative stress. It plays a crucial role in collagen synthesis and is widely utilized in various life science research applications, including studies on cellular metabolism, skin health, and enzymatic reactions. -
Biochemical Reagent
Ap2A disodium is a symmetrical dinucleoside polyphosphate that serves as a biochemical reagent. It exhibits a significant capacity to promote the proliferation of vascular smooth muscle cells. This compound is commonly utilized in research focused on cellular growth and cardiovascular studies. -
Biochemical Assay Reagent
Chitin, derived from crab carapace, is a long-chain polymer of N-acetylglucosamine featuring β-(1-4) linkages. This biopolymer serves as a biochemical assay reagent and is noted for its ability to inhibit the activation of NF-κB p65, as well as alter its translocation to the nucleus. Chitin also interacts with the cell wall of Candida species, exhibiting antifungal and anti-inflammatory properties. It is valuable for research into gastric ulcers and candidiasis, contributing to the understanding of related pathophysiological processes. -
Biochemical Assay Reagent
Ammonium bicarbonate is an analytical reagent used primarily in biochemical assays. It exhibits antifungal activity and is instrumental in various research applications, including laboratory analysis and food processing. Additionally, it serves as a nitrogen source in agricultural fertilization. This reagent's high purity ensures reliable results in experimental setups. -
Biochemical Assay Reagent
Chitosan (≥95% deacetylated, viscosity 100-200 mPa.s) is a biopolymer derived from the deacetylation of chitin, targeting a wide range of microorganisms. It demonstrates notable antimicrobial properties against various bacteria and fungi, making it suitable for a variety of biochemical assays and applications. Its unique properties also lend themselves to research in drug delivery, wound healing, and food preservation. -
Biochemical Assay Reagent
L-Ascorbic acid magnesium serves as an essential biochemical assay reagent and functions as an electron donor and endogenous antioxidant. It selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM, highlighting its pharmacological significance. Additionally, L-Ascorbic acid promotes collagen deposition while inhibiting elastin production. Its anticancer properties are attributed to the generation of reactive oxygen species (ROS), which selectively induce damage in cancer cells, making it a valuable tool for research in cellular and molecular biology. -
Impurity of Hydroxychloroquine
Hydroxychloroquine Impurity E is a chemical impurity associated with Hydroxychloroquine, a synthetic antimalarial agent. Hydroxychloroquine is known to inhibit Toll-like receptor 7/9 (TLR7/9) signaling and has demonstrated efficacy in reducing SARS-CoV-2 infection in vitro. This impurity may be useful for studies investigating the purity and activity of Hydroxychloroquine in various biological contexts. -
Biochemical Assay Reagent
Sodium chloride functions as a biochemical assay reagent and is crucial for cell culture applications. This compound induces the expression of ATP1A1 and promotes the secretion of pro-inflammatory cytokines such as IL-2, TNFα, IL-9, alongside various chemokines. Additionally, sodium chloride has been shown to augment the anti-tumor efficacy of Digoxin in small cell lung cancer models. Its role in driving autoimmune disease is linked to the induction of pathogenic Th17 cells, making it significant for studies in inflammation and immune response. -
Biochemical Assay Reagent
(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98% is a selective agonist for the LPA3 G-protein-coupled receptor. This compound triggers downstream signaling events by activating calcium ion influx and promoting IL-6 release in cancer cells. Additionally, it has been shown to activate MAPK and Akt signaling pathways, making it valuable for research applications focused on ovarian cancer. -
Iimpurity of Lenvatinib
Lenvatinib N-oxide is a significant impurity of Lenvatinib, a multi-targeted tyrosine kinase inhibitor known for its oral bioactivity. This compound serves as an important reference standard in pharmacological studies, aiding the characterization and quality control of Lenvatinib. Researchers may utilize Lenvatinib N-oxide for analytical purposes to assess the purity and stability of Lenvatinib formulations in various biological research contexts. -
Oseltamivir Impurity
Oseltamivir-acetate is an impurity associated with Oseltamivir, a well-known neuraminidase inhibitor utilized in the treatment and prevention of influenza A and B. This compound is valuable for research applications involving the analysis of Oseltamivir's purity and the study of its pharmacological properties in antiviral therapies. Understanding the presence of impurities like Oseltamivir-acetate can aid in the development of more effective influenza treatments and enhance the overall quality of the drug formulation. -
Biochemical Reagent
D-Carnitine is an isomer of the essential nutrient L-carnitine, functioning primarily as a biochemical reagent. It enhances the transport of long-chain fatty acids into the mitochondrial matrix, facilitating their beta-oxidation. Additionally, D-Carnitine exhibits antiparasitic activity, making it useful in various research applications related to metabolism and parasitology. -
Sofosbuvir Impurity
Sofosbuvir impurity G is a diastereoisomeric impurity of Sofosbuvir, which is a potent inhibitor of HCV RNA replication. This compound serves as an important reference standard for quality control and analytical purposes in the research and development of hepatitic C virus treatments. Its characterization is essential for understanding the processing and stability of Sofosbuvir formulations. -
Drug Intermediate
FI-3 is a polycyclic tetramate macrolactam that serves as a critical biosynthetic intermediate derived from Streptomyces sp. SPB78. It exhibits potential antibiotic properties, making it valuable for research in antibacterial development and biochemical pathways related to antibiotic biosynthesis. -
Biochemical Assay Reagent
Acid Red 26 is a biochemical assay reagent primarily used for colorimetric detection in various biological applications. It exhibits strong dyeing properties, making it suitable for staining biological tissues and cells in microscopy studies. This compound is instrumental in analyzing cellular components, monitoring metabolic activity, and validating experimental conditions in life science research. -
Ziprasidone Impurity
Keto Ziprasidone is a known impurity of the antipsychotic agent Ziprasidone, which functions primarily as a combined antagonist of serotonin (5-HT) and dopamine receptors. This compound is crucial for research applications focusing on drug metabolism and pharmacokinetics, particularly in understanding the potential effects of impurities on therapeutic efficacy and safety profiles. Its analysis can aid in the development of quality control measures in pharmaceutical formulations. -
Ziprasidone Impurity
Hydroxy ziprasidone is a known impurity of the antipsychotic agent ziprasidone, which functions primarily as a combined antagonist of both serotonin (5-HT) and dopamine receptors. This compound is useful for researchers studying the pharmacological properties and metabolic pathways of ziprasidone, as well as for quality control in the synthesis of pharmaceutical formulations. Its presence can provide insights into the drug's safety, efficacy, and potential side effects. -
Methotrexate Impurity
Methotrexate γ-Methyl Ester is an impurity of the folate antagonist Methotrexate, specifically identified as Methotrexate 5-methyl ester. This compound is utilized in chemical research to study the properties and potential effects of Methotrexate derivatives. It serves as a valuable tool for understanding the metabolism and biochemical activity of folate-related compounds in various biological systems. -
Biochemical Assay Reagent
L-Sorbitol is a six-carbon sugar alcohol that serves as a versatile biochemical assay reagent. It is commonly utilized in various biochemical experiments and can influence osmotic pressure, making it valuable in studies related to cell biology and metabolism. Additionally, L-Sorbitol can function as a substrate in enzymatic assays and as a cryoprotectant in cell preservation applications. Its role in cellular processes positions it as an essential tool in life science research. -
Biochemical Assay Reagents
Agar is a gelatinous polysaccharide derived from the cell walls of red algae species, including Gelidium and Gracilaria. Its primary mechanism involves forming reversible physical gels through hydrogen bonding, making it an essential medium for cell culture applications. Agar is widely utilized in microbiological assays, plant tissue culture, and various biochemical applications, offering a stable environment for the growth and maintenance of microorganisms and cells in research settings. -
Biochemical Reagent
Sodium tetraborate decahydrate is a versatile biochemical reagent with multiple applications in research. It enhances the activity of antioxidant enzymes such as catalase and superoxide dismutase, contributing to its neuroprotective effects against chromium-induced toxicity. Additionally, sodium tetraborate decahydrate exhibits antibacterial properties by reducing hydrogen sulfide levels and inhibiting the growth of sulfate-reducing bacteria in swine manure. This compound also acts as a triglyceride transesterification catalyst and a flame suppressant for wood cellulose, making it valuable in various scientific investigations. -
Biochemical Reagents
N-Chlorosuccinimide is a potent chlorinating agent primarily used as a biochemical reagent for aliphatic and aromatic chlorination reactions. This versatile compound enhances microbial activity and has been shown to augment the antimicrobial effects of Benzalkonium chloride against biofilm-forming Pseudomonas aeruginosa. Its applications extend to various synthetic and analytical processes, making it a valuable tool in chemical research. -
Biochemical Assay Reagent
Silver nitrite is an inorganic compound with the formula AgNO2, serving as a biochemical assay reagent. It exhibits antimicrobial properties by inhibiting cell division and bacterial growth through interference with protein synthesis. This compound is useful in various research applications, including studies on cellular processes and the investigation of antibacterial mechanisms. -
Biochemical Assay Reagent
Octanohydroxamic acid is a biochemical assay reagent primarily utilized for its role as an extractant for alkaloids in pharmaceutical and natural product research. This compound may also inhibit specific enzymes, including hydroxamate hydrolases, making it valuable for studies related to enzyme activity and inhibition mechanisms. Its versatile applications contribute to the understanding of biochemical pathways and the development of novel therapeutic agents. -
Biochemical Assay Reagent
Protamine from salmon is a biochemical assay reagent that serves as an antagonist to heparin, effectively neutralizing its anticoagulant effects. This compound exhibits antioxidant and antimicrobial properties, making it valuable in various research applications. It is particularly useful in studies involving antithrombin complexes, especially in canine samples pretreated with heparin in vitro. -
Drug Intermediate
3,3-Dimethylacrylic acid is a key intermediate in the synthesis of various pharmaceutical compounds. This small molecule is utilized in the development of drugs, particularly in the creation of polymers and other materials due to its unique structural features. Its versatility as a building block makes it an important reagent in chemical research and drug development applications. -
Biochemical Assay Reagent
Nocardamine, also known as Deferrioxamine E, functions as an iron chelator and iron carrier. It demonstrates antimicrobial activity, making it valuable in studies focused on iron metabolism and microbial interactions. This reagent can be utilized in biochemical assays to investigate its effects on iron-dependent processes and microbial growth. -
Biochemical Assay Reagent
8-Nonynoic acid is a fatty acid that primarily targets bacterial cell membranes through its interaction with fatty acids. It demonstrates significant antibacterial activity against gram-positive bacteria, as well as inhibiting the growth of gram-negative bacteria by blocking fatty acid synthesis. This compound is effective in both aerobic and anaerobic environments, making it a valuable reagent for biochemical assays in microbiological research.
