Catalog No.
Product Name
Application
Product Information
Citations
- Methoxatin (disodium salt) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy.
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Glyoxalase I (GLO1) inhibitor
Glyoxalase I inhibitor (free base) is a potent Glyoxalase I (GLO1) inhibitor, candidate for anticancer agents. - ELX-02 disulfate (NB-124 disulfate) is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). ELX-02 disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations.
- ELX-02 sulfate (NB-124 sulfate) is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). ELX-02 sulfate is being developed as a therapy for genetic diseases caused by nonsense mutations.
- Imisopasem manganese , also known as M40403, or GC4419, is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities.
- Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property.
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triazole DAGL(α) inhibitor
DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100. - S107 hydrochloride is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
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anticholinergic antiparkinsonian agent
Metixene hydrochloride is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM. -
enkephalin degrading enzymes inhibitor
Kelatorphan is a full inhibitor of enkephalin degrading enzymes. -
CDC7 kinase inhibitor
(R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib, Simurosertib (TAK-931) is a selective cycle 7 (CDC7) kinase inhibitor, with an IC50<0.3 nM. - Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens.
- MBC-11 trisodium is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C. Has potential to treat tumor-induced bone disease (TIBD).
- L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of homocysteine; prevents translational incorporation of homocysteine into proteins.
- Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
- Oleanolic acid derivative 1 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
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SAMDC inhibitor
Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. -
CID797718 analog
kb-NB77-78 is an analogue of CID797718, but shows no PKD inhibitory activity. -
TAAR1 agonist
RO5203648 hydrochloride is a partial agonist of Trace amine-associated receptor 1 (TAAR1). -
polymerase inhibitor
ERDRP-0519 is an orally available inhibitor of polymerase that shows efficacy against a lethal morbillivirus infection in a large animal model. -
p18INK inhibitor
NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM). - Isocyclosporin A is a rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.
- Dextromethorphan (Discontinued) (DXM or DM) is an antitussive (cough suppressant) drug of the morphinan class with sedative and dissociative properties.
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3CLpro inhibitor
GC376 is a 3CLpro inhibitor (3C-like protease inhibitor).- Ai-Ai Chou, .et al. , Vet Q, 2024, Dec;44(1):1-13 PMID: 38712855
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inhibitor for GA perception
TSPC is an inhibitor for GA perception by in vitro and in planta evaluations. -
autoinducer of P. fischeri luciferase
N-(beta-ketocaproyl)-L-Homoserine lactone (N-(Ketocaproyl)-L-homoserine lactone, N-(β-Ketocaproyl)-L-hoMoserine lactone) is an autoinducer of P. fischeri luciferase and a component of quorum regulatory sensing. -
chemical UV filter
Homosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage. -
Eph family tyrosine kinase inhibitor
Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor. -
S-adenosylhomocysteine hydrolase inhibitor
3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ?M; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. -
antiproliferative agent
Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line. -
inhibitor of glycogen synthase kinase 3
5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3). -
non-steroidal anti-inflammatory drug
Indoprofen is a non-steroidal anti-inflammatory drug, provide insight into treatments for spinal muscular atrophies. - AH10639 is a novel inhibitor of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.
