Peptides

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  1. Dipeptide

    Fmoc-Phe-Thr(psi(Me,Me)pro)-OH is a dipeptide featuring a unique modified proline residue. This compound is designed to study peptide interactions and protein folding due to its structural variations. Its application is primarily in peptide synthesis and development, making it a valuable tool for researchers investigating peptide libraries and bioconjugation strategies.
  2. Dipeptide

    Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide with a unique structure that incorporates a psi(Me,Me)pro residue. This compound is utilized in peptide synthesis and modification studies due to its ability to influence protein conformation and stability. Its unique features make it valuable for research in peptide-based therapeutics and structural biology.
  3. Dipeptide Et Ester

    Glp-Trp-OEt is a pyroglutamyl-tryptophan derivative functioning as a dipeptide ethyl ester. This compound is primarily utilized in biochemical research to study peptide synthesis and the role of dipeptides in biological systems. Its unique structure makes it valuable for exploring molecular interactions and activity in various biological assays.
  4. Polypeptide

    N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine is designed to interact with the PAICS protein, thereby inhibiting its activity. This compound effectively decreases the accumulation of SAICAR and SAICAr, making it a valuable tool in metabolic and biochemical research focused on purine biosynthesis. Its ability to modulate these pathways can aid in studies related to cancer metabolism and other disorders associated with nucleotide imbalances.
  5. Dipeptide

    Nap-FF is a cell-penetrating dipeptide that facilitates the development of hydrogel-based chemosensors and enhances targeted drug delivery systems. Its ability to penetrate cellular membranes makes it a valuable tool for studying cellular uptake and bioactivity. Researchers can utilize Nap-FF in applications ranging from drug formulation to the design of innovative therapeutic delivery mechanisms.
  6. Peptide Synthesis

    Boc-Glu(OBzl)-OSu is a pivotal reagent in peptide synthesis that introduces glutamate benzyl ester residues into peptides. This compound is designed for solid-phase peptide synthesis, facilitating the formation of key peptide bonds and enhancing the overall efficiency of peptide assembly. Its utility in constructing complex peptides makes it an essential tool for researchers in the field of peptide chemistry.
  7. Dipeptide

    Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH is a synthesized dipeptide designed for use in peptide synthesis and biomolecular research. This compound features unique structural modifications that enhance its stability and bioactivity, making it suitable for studies of protein interactions and enzymatic activity. Its specific applications include facilitating the development of peptide-based therapeutics and probing biological pathways involving tyrosine and threonine residues.
  8. Dipeptide

    Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide that serves as a building block for peptide synthesis. It features a protected glutamic acid and a modified serine residue, allowing for the incorporation of stereochemical diversity in peptide design. This reagent is valuable in biological research aimed at investigating peptide interactions, functional studies, and developing novel therapeutic agents.
  9. Fmoc-Tyr(3-F,tBu)-OH Cyclic Peptide

    Fmoc-Tyr(3-F,tBu)-OH is an Fmoc-protected derivative of tyrosine, featuring a 3-fluoro and tert-butyl substitution. This compound serves as a valuable building block for the synthesis of cyclic peptides, facilitating the incorporation of functional modifications into peptide sequences. Its applications extend to studies involving structural biology and the development of peptide-based therapeutics.
  10. Dipeptide

    Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide featuring a protected tyrosine and a modified serine residue. This compound is primarily utilized for peptide synthesis and modification studies. Its unique structure enables researchers to explore the effects of different amino acid substitutions on peptide functionality and stability in biological systems. This reagent is suitable for applications in drug development, protein mimetics, and therapeutic peptide research.
  11. Dipeptide

    Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide that incorporates a protected asparagine and serine residue. This compound is designed for use in peptide synthesis and can aid in the development of peptide-based therapeutics. Its unique structure provides opportunities for studies involving protein folding and interactions, making it valuable in the field of medicinal chemistry and biochemistry research.
  12. Dipeptide

    Leucylproline is a dipeptide that modulates proteinase activity in a medium-dependent manner. This compound is of significant interest in biochemical research for its potential regulatory roles in protein metabolism and enzymatic functions. Its unique structure and biological activity make it a valuable tool for studies involving dipeptides and proteolytic enzymes.
  13. Nuclear localization peptide

    NHIP peptide is a nuclear localization peptide comprising 20 amino acids. It is predominantly expressed in neuronal-derived cells, such as LUHMES cells, and has been shown to promote the proliferation of 293T cells. NHIP peptide plays a significant role in regulating gene networks associated with neural development and autism spectrum disorder (ASD), making it valuable for research in neurobiology and related fields.
  14. dipeptide

    H-Asp-Ala-OH is a dipeptide comprised of aspartic acid and alanine. This compound can serve as a building block in peptide synthesis and is used in various biochemical assays to study protein interactions and cellular functions. Its unique structure allows researchers to investigate the effects of dipeptides on biological activity, making it valuable for studies in peptide-based drug discovery and development.
  15. Peptide

    Tat-GluR23Y, scrambled is a scrambled variant of the Tat-GluR23Y synthetic peptide. This peptide is designed to inhibit AMPA receptor (AMPAR) endocytosis, thereby contributing to the understanding of long-term depression (LTD) mechanisms in neural signaling. Researchers can utilize this reagent to study synaptic plasticity and related cognitive processes.
  16. Dipeptide

    Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide that incorporates a modified backbone structure. This compound is designed to facilitate peptide synthesis with enhanced stability and specificity in biological environments. It is primarily utilized in research applications focused on peptide engineering, drug delivery systems, and the study of peptide-receptor interactions.
  17. Polycationic Peptide

    Hexaarginine, a polycationic peptide composed of six arginine residues, acts predominantly through cell penetration mechanisms. This reagent is primarily utilized for the intracellular delivery of low-molecular-weight compounds, biomolecules, and particles, facilitating enhanced cellular uptake and distribution. Its efficacy in translocating various agents into cells makes it valuable for research applications in drug delivery and gene therapy.
  18. Polypeptide

    Fmoc-Thr(GalNAc(Ac)3-β-D)-OH is a polypeptide that primarily targets cancer-specific signaling pathways. This compound exhibits notable biological activity through the inhibition of cancer cell proliferation, while also enhancing the immune response. Its applications in research include investigating cellular mechanisms of cancer progression and immunotherapy development.
  19. Dipeptide

    Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide that features a unique psi (Me, Me) proline derivative. This compound serves as an important building block for peptide synthesis and can be used in the development of peptide-based therapeutics. Its structural modifications facilitate studies in various biological activities, including protein-protein interactions and enzyme activity modulation.
  20. Tripeptide

    H-Gly-Lys-Gly-OH is a tripeptide composed of glycine and lysine, which serves as a building block for various protein synthesis pathways. This reagent is particularly relevant in the study of casein and soybean protein synthesis, making it a valuable tool in biochemical research. Its unique sequence may also be of interest in exploring peptide function and interactions in biological systems.
  21. Dipeptide

    Fmoc-Val-Ser(psi(Me,Me)pro)-OH is a dipeptide that serves as a valuable building block for the synthesis of peptides and peptidomimetics. Its unique structure, featuring a psi(Me,Me)pro group, enhances conformational stability and bioactivity. This reagent is particularly useful in studies related to peptide design and optimization, as well as in the development of therapeutics targeting protein-protein interactions.
  22. Dipeptide

    Fmoc-Leu-Thr(psi(Me,Me)pro)-OH is a dipeptide characterized by the incorporation of a psi(Me,Me)proline moiety. This compound is utilized in peptide synthesis and can facilitate the study of peptide conformation and stability. Its unique structure makes it an important tool for examining protein interactions and developing peptide-based therapeutics.
  23. Synuclein-γ Inhibitor

    ANK peptide is a selective synuclein-γ (SNCG) inhibitor that effectively disrupts the interaction between SNCG and BubR1. This interference enhances the sensitivity of breast cancer cells to antimicrotubule agents, including nocodazole and paclitaxel. ANK peptide is valuable for research into cancer biology, particularly in understanding the molecular mechanisms of drug resistance in breast cancer.
  24. Lytic Peptide

    CyPep-1 is a cationic lytic peptide that exhibits significant antitumor activity. Its mechanism involves interaction with the negatively charged membranes of cancer cells, resulting in strong cytotoxic effects. CyPep-1 demonstrates potent cytolytic activity both in vivo and in vitro, making it a valuable tool for research applications focused on solid tumors.
  25. Dipeptide

    Fmoc-Leu-Ser(psi(Me,Me)pro)-OH is a synthetic dipeptide that incorporates an innovative psi-me(2)pro moiety. This compound serves as a valuable tool in peptide synthesis and exploration of protein interactions. Its unique structure enables researchers to investigate peptide conformation and stability, making it suitable for various applications in biomedical research and drug development.
  26. Polypeptide

    Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is a specialized polypeptide designed for use in fluorescence-based assays. This compound aids in tracking peptide interactions and localization within various biological systems due to its fluorescent properties. It is applicable in research areas focused on peptide synthesis, protein engineering, and cell imaging studies.
  27. Dipeptide

    Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH is a novel dipeptide with a focus on peptide synthesis. This compound exhibits significant potential for modulating protein interactions and enhancing peptide stability. It is particularly useful in the design of bioactive peptides and in studies that explore protein folding and aggregation. Researchers can utilize this compound for various applications in drug discovery and development, as well as in biochemical assays.
  28. Peptide Derivative

    Boc-Lys(Z)-OH (DCHA) is a peptide derivative primarily utilized in the synthesis of thymosin β4, βg, and β6 fragments. This compound has been shown to enhance E-rosette forming capacity in models of Lupus Nephritis. Additionally, Boc-Lys(Z)-OH (DCHA) serves as a reagent in the production of peptidyl thrombin inhibitors, contributing to various biochemical research applications.
  29. Peptide

    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met is a peptide sequence designed for biochemical research applications. This compound is utilized to study protein-protein interactions and enzymatic processes, and it may serve as a model for investigating peptide folding and stability. Its structural properties can facilitate the exploration of receptor binding and signaling pathways in various biological contexts.
  30. Dipeptide

    H-Met-Pro-OH is a dipeptide composed of methionine and proline. It serves as a substrate for the enzyme aminopeptidase P (APP) and plays a role in the activity of skin fibroblast prolidase. This reagent is valuable in studies related to peptide metabolism, enzymatic activity, and fibroblast function, making it suitable for a variety of biochemical and cellular research applications.
  31. Dipeptide

    Fmoc-Val-Thr(psi(Me,Me)pro)-OH is a dipeptide comprised of valine and threonine, modified with a psi(Me,Me)proline residue. This compound is utilized in peptide synthesis and can serve as a tool to study protein interactions and structure-activity relationships. Its structural features make it valuable for investigations in the fields of medicinal chemistry and peptide therapeutics.
  32. Methionine Dipeptide

    D-Met-Met is a methionine dipeptide that serves as an orally active compound, primarily involved in cellular metabolism and protein synthesis. This reagent exhibits key biological activity in promoting antioxidant defenses, potential neuroprotective effects, and supporting muscle recovery. D-Met-Met is applicable in research related to nutritional supplements, therapeutic development, and studies on amino acid metabolism.
  33. Dipeptide

    Glycyl-L-Proline TFA is a dipeptide composed of glycine and L-proline, primarily utilized in studies investigating the relationship between transmembrane potential and proton gradients in cellular transport mechanisms. This compound is valuable in research exploring intestinal absorption processes and can provide insights into peptide transport systems. Its unique structure facilitates investigations into the physiological roles of dipeptides in membrane dynamics and transport efficiency.
  34. Dipeptide

    Lysylcysteine is a dipeptide formed by the combination of lysine and cysteine. It has been shown to possess antioxidant properties and may influence cellular signaling pathways. This compound is primarily used in research related to protein structure, redox biology, and as a potential therapeutic agent in oxidative stress-related disorders.
  35. Dipeptide

    L-Phenylalanyl-L-glutamic acid is a dipeptide that serves as a high-affinity substrate for the peptide transporter PEPT2, demonstrated by a Ki value of 0.022 mM. In contrast, it exhibits a lower affinity for PEPT1, with a Ki value of 0.18 mM. This compound can be utilized in research focused on peptide transport mechanisms and their implications in pharmacology and drug delivery systems.
  36. Peptide Coupling Reagent

    HATU (Hexafluoro-2-(mercaptomethyl) pyridine) is a third-generation uronium salt employed as a peptide coupling reagent. It enhances the rate of peptide coupling reactions and activates amino acids, facilitating peptide bond formation in both solution-phase and solid-phase syntheses. Additionally, HATU supports peptide assembly, fragment coupling, and linear peptide cyclization. It is also effective in promoting N-acylation of chitosan to produce amide-linked cationic derivatives with a modifiable degree of substitution, making it a valuable tool in amine acylation processes.
  37. Peptide Coupling Additive

    Ethyl 2-cyano-2-(hydroxyimino)acetate serves as a peptide coupling additive, primarily functioning to suppress racemization during peptide synthesis. This compound enhances coupling efficiency in both solution-phase and solid-phase synthesis, making it a valuable tool in peptide chemistry. Its ability to promote higher yields and improve product purity underscores its significance in various biological research applications.
  38. Tripeptide

    Copper tripeptide (GHK-Cu) is a tripeptide known for its role as a natural modulator in skin regeneration. This compound enhances messenger RNA levels for critical extracellular matrix components such as collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Additionally, Copper tripeptide serves as a chemoattractant during wound healing, promoting the recruitment of inflammatory and endothelial cells, thus playing a vital role in tissue repair and regeneration. Its biological activities make it valuable for research applications focused on dermal health and regenerative medicine.
  39. Peptide Coupling Reagent

    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate functions as an effective peptide coupling reagent, facilitating the formation of peptide bonds between amino and carboxyl groups. This compound serves as a versatile BOP analog in peptide synthesis, promoting the efficient construction of various peptide compounds. Its application is essential in the development of peptide-based therapeutics and research in synthetic chemistry.
  40. Polypeptide

    INF7 is a derivative of the N-terminal domain of the HA2 protein that functions primarily as a polypeptide. It disrupts the stability of endosomal membranes through a mechanism that does not rely on membrane fusion, making it effective in enhancing the endosomal escape of complex or liposome-encapsulated proteins. This property allows for improved intracellular signaling and increased retention of molecular imaging probes when co-encapsulated with INF7 in liposomes, facilitating various biological research applications.
  41. Cross-Linked Peptide

    Azide-A-DSBSO crosslinker is a homobifunctional, azide-labeled crosslinking reagent that targets lysine residues through an NHS ester reaction. This membrane-permeable and acid-cleavable compound is particularly useful in cross-linking mass spectrometry (XL-MS) to investigate protein-protein interactions. Its mass spectrometry-cleavable properties enable efficient analysis of cross-linked complexes, facilitating deeper insights into protein dynamics and interactions in biological systems.
  42. Anticancer Peptide

    GE11 is an active anticancer peptide that serves as a smart carrier in colloidal drug delivery systems for antitumor agents. Its ability to selectively target cancer cells enhances the therapeutic efficacy of combined treatments. GE11 is valuable for research applications aimed at understanding tumor biology and developing innovative cancer therapies.
  43. Muscle Homing Peptide

    Muscle Homing Peptide M12 targets surface proteins on muscle cells, facilitating enhanced cellular uptake of nanoparticles within myoblasts in vitro. Its ability to bind specifically to muscle tissue makes it a valuable tool in drug delivery applications. Muscle Homing Peptide M12 can be covalently conjugated to PLGA-PEG nanoparticles through N-terminal α-amino groups using the N-hydroxysuccinimide ester reaction, thereby improving the localization and effectiveness of therapeutic agents in muscle tissues.
  44. Neuropeptide

    Ercanetide is a synthetic analogue of cyclic glycine proline (cGP) that functions as a neuropeptide. It demonstrates neuroprotective effects following ischemic brain injury and has been shown to enhance motor function in rat models of Parkinson's disease. Ercanetide's ability to cross the blood-brain barrier makes it a valuable tool for research concerning ischemic brain injury and conditions such as Angelman syndrome.
  45. Biochemical Assay Reagent

    Casein phosphopeptide is a biochemical assay reagent that serves as a biologically relevant compound for research in life sciences. It plays a crucial role in studies of calcium and phosphate metabolism, and is frequently utilized in the investigation of mineral absorption and biological interactions in dairy products. Additionally, its unique properties make it valuable for exploring protein stability and functionality in various biochemical applications.
  46. Drug delivery peptide

    CAQK peptide is a drug delivery peptide that selectively targets injured mouse brain tissue. It binds to demyelinating areas while being absent from healthy tissues due to its interaction with an upregulated proteoglycan complex associated with brain injuries. CAQK peptide's ability to penetrate the blood-brain barrier makes it a valuable tool for therapeutic applications in neurological research and drug delivery strategies.
  47. Tumor Cell Chemotactic Peptide

    Chemotactic Domain of Elastin is a synthetic peptide derived from elastin that exhibits chemotactic activity specifically towards tumor cells, including M27 tumor cells. This peptide is valuable for cancer research, particularly in studies examining tumor cell migration and invasion mechanisms. Its ability to promote chemotaxis makes it a useful tool for elucidating the role of extracellular matrix components in tumor progression.
  48. Fluorogenic Peptide Substrate

    Gly-Phe-AMC is a fluorogenic peptide substrate that consists of a glycine-phenylalanine sequence linked to the fluorophore AMC. This compound is specifically utilized as a substrate for cathepsin C and is instrumental in detecting the activity of various proteases. Its ability to fluoresce upon cleavage makes Gly-Phe-AMC a valuable tool in biochemical assays and protease activity studies.
  49. CRT

    Iron Peptide Mimic

    CRT is an iron peptide mimic that exhibits the ability to bind to apo-transferrin (apo-Tf). This characteristic makes CRT a valuable tool for modifying nanoparticles, ultimately enhancing drug delivery efficiency in various therapeutic applications. Its unique binding properties position it as a critical reagent in research focused on improving drug transport and bioavailability.
  50. Chemerin Peptide

    Chemerin15 is a chemerin peptide that targets macrophage (MPhi) function, enhancing their phagocytic activity towards microbial particles and apoptotic cells. It also exerts an inhibitory effect on macrophage activation and can mitigate peritonitis induced by the zymosan component of yeast cell walls. This peptide is valuable for research applications studying innate immunity and macrophage-mediated processes in inflammation.

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