Catalog No.
Product Name
Application
Product Information
Citations
-
Polypeptide
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH is a polypeptide that primarily targets cancer-specific signaling pathways. This compound exhibits notable biological activity through the inhibition of cancer cell proliferation, while also enhancing the immune response. Its applications in research include investigating cellular mechanisms of cancer progression and immunotherapy development. -
Dipeptide
Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide that features a unique psi (Me, Me) proline derivative. This compound serves as an important building block for peptide synthesis and can be used in the development of peptide-based therapeutics. Its structural modifications facilitate studies in various biological activities, including protein-protein interactions and enzyme activity modulation. -
Tripeptide
H-Gly-Lys-Gly-OH is a tripeptide composed of glycine and lysine, which serves as a building block for various protein synthesis pathways. This reagent is particularly relevant in the study of casein and soybean protein synthesis, making it a valuable tool in biochemical research. Its unique sequence may also be of interest in exploring peptide function and interactions in biological systems. -
Dipeptide
Fmoc-Val-Ser(psi(Me,Me)pro)-OH is a dipeptide that serves as a valuable building block for the synthesis of peptides and peptidomimetics. Its unique structure, featuring a psi(Me,Me)pro group, enhances conformational stability and bioactivity. This reagent is particularly useful in studies related to peptide design and optimization, as well as in the development of therapeutics targeting protein-protein interactions. -
Dipeptide
Fmoc-Leu-Thr(psi(Me,Me)pro)-OH is a dipeptide characterized by the incorporation of a psi(Me,Me)proline moiety. This compound is utilized in peptide synthesis and can facilitate the study of peptide conformation and stability. Its unique structure makes it an important tool for examining protein interactions and developing peptide-based therapeutics. -
Synuclein-γ Inhibitor
ANK peptide is a selective synuclein-γ (SNCG) inhibitor that effectively disrupts the interaction between SNCG and BubR1. This interference enhances the sensitivity of breast cancer cells to antimicrotubule agents, including nocodazole and paclitaxel. ANK peptide is valuable for research into cancer biology, particularly in understanding the molecular mechanisms of drug resistance in breast cancer. -
Lytic Peptide
CyPep-1 is a cationic lytic peptide that exhibits significant antitumor activity. Its mechanism involves interaction with the negatively charged membranes of cancer cells, resulting in strong cytotoxic effects. CyPep-1 demonstrates potent cytolytic activity both in vivo and in vitro, making it a valuable tool for research applications focused on solid tumors. -
Dipeptide
Fmoc-Leu-Ser(psi(Me,Me)pro)-OH is a synthetic dipeptide that incorporates an innovative psi-me(2)pro moiety. This compound serves as a valuable tool in peptide synthesis and exploration of protein interactions. Its unique structure enables researchers to investigate peptide conformation and stability, making it suitable for various applications in biomedical research and drug development. -
Polypeptide
Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is a specialized polypeptide designed for use in fluorescence-based assays. This compound aids in tracking peptide interactions and localization within various biological systems due to its fluorescent properties. It is applicable in research areas focused on peptide synthesis, protein engineering, and cell imaging studies. -
Dipeptide
Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH is a novel dipeptide with a focus on peptide synthesis. This compound exhibits significant potential for modulating protein interactions and enhancing peptide stability. It is particularly useful in the design of bioactive peptides and in studies that explore protein folding and aggregation. Researchers can utilize this compound for various applications in drug discovery and development, as well as in biochemical assays. -
Peptide Derivative
Boc-Lys(Z)-OH (DCHA) is a peptide derivative primarily utilized in the synthesis of thymosin β4, βg, and β6 fragments. This compound has been shown to enhance E-rosette forming capacity in models of Lupus Nephritis. Additionally, Boc-Lys(Z)-OH (DCHA) serves as a reagent in the production of peptidyl thrombin inhibitors, contributing to various biochemical research applications. -
Peptide
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met is a peptide sequence designed for biochemical research applications. This compound is utilized to study protein-protein interactions and enzymatic processes, and it may serve as a model for investigating peptide folding and stability. Its structural properties can facilitate the exploration of receptor binding and signaling pathways in various biological contexts. -
Dipeptide
H-Met-Pro-OH is a dipeptide composed of methionine and proline. It serves as a substrate for the enzyme aminopeptidase P (APP) and plays a role in the activity of skin fibroblast prolidase. This reagent is valuable in studies related to peptide metabolism, enzymatic activity, and fibroblast function, making it suitable for a variety of biochemical and cellular research applications. -
Dipeptide
Fmoc-Val-Thr(psi(Me,Me)pro)-OH is a dipeptide comprised of valine and threonine, modified with a psi(Me,Me)proline residue. This compound is utilized in peptide synthesis and can serve as a tool to study protein interactions and structure-activity relationships. Its structural features make it valuable for investigations in the fields of medicinal chemistry and peptide therapeutics. -
Methionine Dipeptide
D-Met-Met is a methionine dipeptide that serves as an orally active compound, primarily involved in cellular metabolism and protein synthesis. This reagent exhibits key biological activity in promoting antioxidant defenses, potential neuroprotective effects, and supporting muscle recovery. D-Met-Met is applicable in research related to nutritional supplements, therapeutic development, and studies on amino acid metabolism. -
Dipeptide
Glycyl-L-Proline TFA is a dipeptide composed of glycine and L-proline, primarily utilized in studies investigating the relationship between transmembrane potential and proton gradients in cellular transport mechanisms. This compound is valuable in research exploring intestinal absorption processes and can provide insights into peptide transport systems. Its unique structure facilitates investigations into the physiological roles of dipeptides in membrane dynamics and transport efficiency. -
Dipeptide
Lysylcysteine is a dipeptide formed by the combination of lysine and cysteine. It has been shown to possess antioxidant properties and may influence cellular signaling pathways. This compound is primarily used in research related to protein structure, redox biology, and as a potential therapeutic agent in oxidative stress-related disorders. -
Dipeptide
L-Phenylalanyl-L-glutamic acid is a dipeptide that serves as a high-affinity substrate for the peptide transporter PEPT2, demonstrated by a Ki value of 0.022 mM. In contrast, it exhibits a lower affinity for PEPT1, with a Ki value of 0.18 mM. This compound can be utilized in research focused on peptide transport mechanisms and their implications in pharmacology and drug delivery systems. -
Peptide Coupling Reagent
HATU (Hexafluoro-2-(mercaptomethyl) pyridine) is a third-generation uronium salt employed as a peptide coupling reagent. It enhances the rate of peptide coupling reactions and activates amino acids, facilitating peptide bond formation in both solution-phase and solid-phase syntheses. Additionally, HATU supports peptide assembly, fragment coupling, and linear peptide cyclization. It is also effective in promoting N-acylation of chitosan to produce amide-linked cationic derivatives with a modifiable degree of substitution, making it a valuable tool in amine acylation processes. -
Peptide Coupling Additive
Ethyl 2-cyano-2-(hydroxyimino)acetate serves as a peptide coupling additive, primarily functioning to suppress racemization during peptide synthesis. This compound enhances coupling efficiency in both solution-phase and solid-phase synthesis, making it a valuable tool in peptide chemistry. Its ability to promote higher yields and improve product purity underscores its significance in various biological research applications. -
Tripeptide
Copper tripeptide (GHK-Cu) is a tripeptide known for its role as a natural modulator in skin regeneration. This compound enhances messenger RNA levels for critical extracellular matrix components such as collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Additionally, Copper tripeptide serves as a chemoattractant during wound healing, promoting the recruitment of inflammatory and endothelial cells, thus playing a vital role in tissue repair and regeneration. Its biological activities make it valuable for research applications focused on dermal health and regenerative medicine. -
Peptide Coupling Reagent
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate functions as an effective peptide coupling reagent, facilitating the formation of peptide bonds between amino and carboxyl groups. This compound serves as a versatile BOP analog in peptide synthesis, promoting the efficient construction of various peptide compounds. Its application is essential in the development of peptide-based therapeutics and research in synthetic chemistry. -
Polypeptide
INF7 is a derivative of the N-terminal domain of the HA2 protein that functions primarily as a polypeptide. It disrupts the stability of endosomal membranes through a mechanism that does not rely on membrane fusion, making it effective in enhancing the endosomal escape of complex or liposome-encapsulated proteins. This property allows for improved intracellular signaling and increased retention of molecular imaging probes when co-encapsulated with INF7 in liposomes, facilitating various biological research applications. -
Cross-Linked Peptide
Azide-A-DSBSO crosslinker is a homobifunctional, azide-labeled crosslinking reagent that targets lysine residues through an NHS ester reaction. This membrane-permeable and acid-cleavable compound is particularly useful in cross-linking mass spectrometry (XL-MS) to investigate protein-protein interactions. Its mass spectrometry-cleavable properties enable efficient analysis of cross-linked complexes, facilitating deeper insights into protein dynamics and interactions in biological systems. -
Anticancer Peptide
GE11 is an active anticancer peptide that serves as a smart carrier in colloidal drug delivery systems for antitumor agents. Its ability to selectively target cancer cells enhances the therapeutic efficacy of combined treatments. GE11 is valuable for research applications aimed at understanding tumor biology and developing innovative cancer therapies. -
Muscle Homing Peptide
Muscle Homing Peptide M12 targets surface proteins on muscle cells, facilitating enhanced cellular uptake of nanoparticles within myoblasts in vitro. Its ability to bind specifically to muscle tissue makes it a valuable tool in drug delivery applications. Muscle Homing Peptide M12 can be covalently conjugated to PLGA-PEG nanoparticles through N-terminal α-amino groups using the N-hydroxysuccinimide ester reaction, thereby improving the localization and effectiveness of therapeutic agents in muscle tissues. -
Neuropeptide
Ercanetide is a synthetic analogue of cyclic glycine proline (cGP) that functions as a neuropeptide. It demonstrates neuroprotective effects following ischemic brain injury and has been shown to enhance motor function in rat models of Parkinson's disease. Ercanetide's ability to cross the blood-brain barrier makes it a valuable tool for research concerning ischemic brain injury and conditions such as Angelman syndrome. -
Biochemical Assay Reagent
Casein phosphopeptide is a biochemical assay reagent that serves as a biologically relevant compound for research in life sciences. It plays a crucial role in studies of calcium and phosphate metabolism, and is frequently utilized in the investigation of mineral absorption and biological interactions in dairy products. Additionally, its unique properties make it valuable for exploring protein stability and functionality in various biochemical applications. -
Drug delivery peptide
CAQK peptide is a drug delivery peptide that selectively targets injured mouse brain tissue. It binds to demyelinating areas while being absent from healthy tissues due to its interaction with an upregulated proteoglycan complex associated with brain injuries. CAQK peptide's ability to penetrate the blood-brain barrier makes it a valuable tool for therapeutic applications in neurological research and drug delivery strategies. -
Tumor Cell Chemotactic Peptide
Chemotactic Domain of Elastin is a synthetic peptide derived from elastin that exhibits chemotactic activity specifically towards tumor cells, including M27 tumor cells. This peptide is valuable for cancer research, particularly in studies examining tumor cell migration and invasion mechanisms. Its ability to promote chemotaxis makes it a useful tool for elucidating the role of extracellular matrix components in tumor progression. -
Fluorogenic Peptide Substrate
Gly-Phe-AMC is a fluorogenic peptide substrate that consists of a glycine-phenylalanine sequence linked to the fluorophore AMC. This compound is specifically utilized as a substrate for cathepsin C and is instrumental in detecting the activity of various proteases. Its ability to fluoresce upon cleavage makes Gly-Phe-AMC a valuable tool in biochemical assays and protease activity studies. -
Iron Peptide Mimic
CRT is an iron peptide mimic that exhibits the ability to bind to apo-transferrin (apo-Tf). This characteristic makes CRT a valuable tool for modifying nanoparticles, ultimately enhancing drug delivery efficiency in various therapeutic applications. Its unique binding properties position it as a critical reagent in research focused on improving drug transport and bioavailability. -
Chemerin Peptide
Chemerin15 is a chemerin peptide that targets macrophage (MPhi) function, enhancing their phagocytic activity towards microbial particles and apoptotic cells. It also exerts an inhibitory effect on macrophage activation and can mitigate peritonitis induced by the zymosan component of yeast cell walls. This peptide is valuable for research applications studying innate immunity and macrophage-mediated processes in inflammation. -
Kidney-targeting Peptide
Kidney-targeting peptide is a specialized targeting agent designed to enhance renal delivery of therapeutic compounds. It significantly improves the renal targeting capability of Isoquercitrin, facilitating targeted interventions in kidney-related studies. This peptide holds potential for applications in research on diabetic nephropathy, enabling more effective exploration of kidney-specific drug delivery and treatment strategies. -
Glycopeptide
G0 N-glycan-Asn is a glycopeptide characterized by the presence of a G0 N-glycan structure. This reagent is valuable for biochemical studies focusing on glycosylation patterns and their effects on protein function. Its applications extend to research in cellular signaling, protein interactions, and the development of glycoprotein-based assays. -
Peptide Conjugate
GE11, Cys Conjugated is a peptide conjugate that targets Epidermal Growth Factor Receptor (EGFR) for biological applications. The compound comprises GE11 linked to a GGGGC sequence, facilitating the synthesis of stimulus-responsive peptide nanomaterials (SRPNs). This reagent is particularly useful in photoacoustic imaging and cancer research, including investigations into triple-negative breast cancer (TNBC). -
Peptide Nucleic Acid Monomer
Fmoc-PNA-C(Bhoc)-OH is a peptide nucleic acid (PNA) monomer that plays a crucial role in the synthesis of PNA compounds. Due to its chemical properties, this monomer facilitates the formation of stable hybridization with complementary nucleic acid sequences. It is widely utilized in molecular biology research for applications such as gene targeting, antisense therapies, and the development of diagnostic tools. -
GRP10 Receptor Ligand
Prolactin-Releasing Peptide (1-31) (rat) is a ligand for the UHR-1/GRP10 receptor. This peptide is known to modulate physiological processes by reducing fasting-induced food intake and elevating plasma levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone in rat models. It is valuable for research applications focusing on appetite regulation and endocrine function. -
Thyroid Hormone Peptide
Calcitonin, eel is a thyroid hormone peptide known for its role in regulating calcium homeostasis. It functions by inhibiting osteoclast activity, thereby reducing bone resorption and promoting calcium deposition in bones. This compound is extensively utilized in research related to postmenopausal osteoporosis and other calcium-related disorders, providing insights into bone metabolism and potential therapeutic strategies. -
Pro-TRH Connecting Peptide
Prepro-TRH-(160-169) is a peptide derived from the pro-TRH prohormone that plays a crucial role in the release of thyrotropin (TSH) by amplifying the effects of thyrotropin-releasing hormone (TRH). This connecting peptide is instrumental in investigating the regulation of TSH secretion and the broader implications of TRH in endocrine function. Prepro-TRH-(160-169) is valuable for research into thyroid physiology, neuroendocrine signaling, and related disorders. -
Building Block in Solid-phase Peptide Synthesis
Fmoc-Trp(Me)-OH is a protected amino acid derivative that functions as a building block in solid-phase peptide synthesis. By introducing a methyl group at the nitrogen atom of the indole ring of tryptophan and utilizing the Fmoc protecting group, Fmoc-Trp(Me)-OH facilitates the assembly of peptides with enhanced stability and specificity. This reagent is widely employed in protein synthesis and various biochemical applications, enabling researchers to study protein interactions and functionalities. -
Dipeptide
Glycyl-L-tyrosine is a synthetic dipeptide that serves as a source of tyrosine, an essential amino acid involved in the synthesis of neurotransmitters such as dopamine and norepinephrine. It is commonly used in research applications related to neurobiology and nutritional studies, providing insights into amino acid supplementation's effects on cognitive function and mood regulation. -
Building Block in Solid-phase Peptide Synthesis
Fmoc-N-Me-Leu-OH is an N-Fmoc-N-methyl amino acid that serves as a crucial building block in solid-phase peptide synthesis (SPPS). This compound allows for the incorporation of N-methylleucine residues into peptide sequences, significantly improving enzymatic stability, modifying conformational flexibility, and potentially altering the biological activity of the synthesized peptides. Its use in peptide coupling reactions makes it a valuable reagent for research in peptide chemistry and drug development. -
Tumor Target Peptide
NY-ESO-1 (157-165) peptide is a tumor-associated peptide fragment derived from the NY-ESO-1 protein. This peptide is recognized by CD8+ T cells in HLA-A2 positive individuals, promoting significant immune activation and responses. Its expression in various tumors makes NY-ESO-1 (157-165) peptide a valuable candidate for research into tumor immunotherapy approaches. -
Dipeptide
Fmoc-Ala-Ala-OH is a self-assembling dipeptide featuring a fluorenylmethoxycarbonyl (Fmoc) moiety, designed for creating nanofiber networks. When exposed to conditions below pH 4, this dipeptide forms a hydrogel scaffold with over 99% water content, exhibiting fiber diameters around 22 nm that closely resemble extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH facilitates cell adhesion and proliferation while preserving cellular phenotype, thereby mimicking the ECM. This reagent is particularly valuable in tissue engineering and 3D cell culture applications, making it ideal for in vitro studies of chondrocytes and other cell types. -
Dipeptide Derivative
Z-Val-Ala-OH is a dipeptide derivative primarily composed of valine and alanine. This compound is utilized in the study of peptide synthesis and enzymatic activity, providing researchers with insight into protein structure and function. Its applications extend to various fields such as drug development, molecular biology, and biochemistry, facilitating the exploration of peptide interactions and biological pathways. -
Peptide Derivative
Fmoc-N-Me-Val-OH is a modified peptide derivative that incorporates a N-methylated valine residue. This compound is primarily utilized in peptide synthesis to enhance the stability and bioactivity of peptides. Its unique structural features facilitate improved binding affinity and resistance to proteolytic degradation, making it valuable in research applications focused on drug development and therapeutic peptide engineering. -
Dipeptide
H-Ala-Ala-OH (L-Alanyl-L-alanine) is a nonpolar dipeptide that serves as a substrate for transport via the proton/amino acid symport mechanism in human intestinal Caco-2 cells. This compound facilitates the absorption of alanine, contributing to cytoplasmic acidification. H-Ala-Ala-OH is valuable in studies of peptide transport mechanisms and amino acid metabolism, offering insights into gut absorption processes and cellular pH regulation. -
Peptide Synthesis
Fmoc-N-Me-Ile-OH is an Fmoc-protected amino acid that serves as a building block in peptide synthesis. Its unique N-methyl substitution enhances the stability and bioactivity of peptides, making it useful in the development of bioactive compounds and pharmaceuticals. This reagent is particularly valuable for researchers in the fields of medicinal chemistry and peptide engineering, facilitating the creation of structurally diverse peptides for various applications. -
Polypeptide
H-Gly-Arg-Ala-Asp-Ser-Pro-OH (GRADSP) is a polypeptide designed as a negative control for the GRGDSPK peptide. This compound lacks the integrin-binding RGD motif, making it an essential tool for validating the specificity of RGD-containing peptides in cellular assays. Its use is critical in studies focusing on cell adhesion, migration, and signaling pathways affected by integrin interactions.
