Peptides

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  1. Cell Penetrating Peptide

    M918 is a cell-penetrating peptide that facilitates internalization by cells through endocytosis. Demonstrating effective penetration of a wide range of cell types without inducing toxicity, M918 is a valuable tool for advancing gene therapy and drug delivery system research. Its ability to traverse cellular membranes enhances its potential applications in therapeutic development and cellular studies.
  2. Biologically Active Peptide

    Cardiogen is a short biologically active peptide (Ala-Glu-Asp-Arg) that primarily interacts with nucleic acids. It demonstrates a selective quenching effect on the fluorescence of methylated and unmethylated λ phage DNA-ethidium bromide complexes, while exhibiting a milder quenching effect on certain double-stranded deoxyribooligonucleotides. This peptide is valuable for research applications involving DNA-protein interactions and fluorescence-based assays in molecular biology.
  3. Oligopeptide

    Ac-Lys-D-Ala-D-Ala-OH is an oligopeptide that serves as a crucial inhibitor of bacterial cell wall synthesis by mimicking the structure of natural peptidoglycan precursors. Its primary activity is to interfere with the transpeptidation step, which is integral to maintaining bacterial cell integrity. This oligopeptide is widely used in biochemical research to study antibiotic resistance mechanisms and the development of novel antimicrobial agents.
  4. Self-assembling Peptide

    Ac-ILVAGK-NH2 is a self-assembling peptide designed to support the maintenance of pluripotency in human H1 embryonic stem cells. This peptide facilitates the creation of a favorable microenvironment for stem cell culture, promoting sustained proliferation and differentiation potential. Its applications extend to stem cell research and regenerative medicine, making it a valuable tool for investigating stem cell biology and tissue engineering.
  5. Model Peptide

    WALP23 is a synthetic model peptide that targets lipid bilayer interactions. It induces heterogeneity in lipid bilayers, generating stripe-like microdomains within DPPC bilayers. This peptide is utilized to investigate protein-membrane interactions and to elucidate helical orientation during their association processes, making it valuable for research in membrane biophysics and cell biology.
  6. MBP Inhibitor

    J5 peptide is a competitive inhibitor of myelin basic protein (MBP) that prevents the binding of MBP85-99 to HLA-DR2. This peptide has demonstrated efficacy in alleviating PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in murine models. J5 peptide is relevant for research on inflammatory and immune diseases, particularly in studies targeting autoimmune mechanisms.
  7. Gold-binding Peptide

    AuBP1 is a gold-binding peptide that specifically interacts with gold nanoparticles. This peptide demonstrates notable affinity for gold substrates, making it a valuable tool for applications in bioconjugation, targeted drug delivery, and nanomaterials research. Its functionality in binding gold enhances its utility in biosensors and imaging studies, facilitating advancements in nanotechnology and biomedical fields.
  8. Peptide

    TANELNLLILR is a peptide derived from peanut proteins that acts as a specific marker for peanut allergens. This peptide is utilized in analytical methods such as UHPLC-MS/MS for the detection and quantification of peanut allergens in various samples. Its application supports research in food safety, allergy diagnostics, and monitoring peanut-related allergic reactions.
  9. Peptide Substrate

    Boc-Val-Gly-Arg-AMC is a peptide substrate designed for the analysis of proteasome activity. This compound serves as a sensitive fluorogenic reporter, enabling the quantification of proteolytic processes in biological samples. Its utility extends to various research applications, including drug discovery and the study of cellular protein degradation mechanisms.
  10. Repetitive Sequence Constituting Elastin-like Peptides

    VPGVG is a repeating sequence that forms elastin-like peptides, derived from the hydrophobic regions of vertebrate elastin. It exhibits temperature-responsive properties, making it suitable for applications in biomaterials research and development. This compound is instrumental in studies focused on biomimetic materials, tissue engineering, and controlled drug delivery systems.
  11. Peptide

    Galanin-B2 is a neuropeptide that targets galanin receptors, demonstrating significant activity in epilepsy models. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for studies related to neurological disorders and potential therapeutic applications in epilepsy research. Its unique properties facilitate investigations into the modulation of neuronal excitability and synaptic transmission.
  12. Dipeptide

    Nap-FF is a cell-penetrating dipeptide that facilitates the development of hydrogel-based chemosensors and enhances targeted drug delivery systems. Its ability to penetrate cellular membranes makes it a valuable tool for studying cellular uptake and bioactivity. Researchers can utilize Nap-FF in applications ranging from drug formulation to the design of innovative therapeutic delivery mechanisms.
  13. Peptide Synthesis

    Boc-Glu(OBzl)-OSu is a pivotal reagent in peptide synthesis that introduces glutamate benzyl ester residues into peptides. This compound is designed for solid-phase peptide synthesis, facilitating the formation of key peptide bonds and enhancing the overall efficiency of peptide assembly. Its utility in constructing complex peptides makes it an essential tool for researchers in the field of peptide chemistry.
  14. Dipeptide

    Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH is a synthesized dipeptide designed for use in peptide synthesis and biomolecular research. This compound features unique structural modifications that enhance its stability and bioactivity, making it suitable for studies of protein interactions and enzymatic activity. Its specific applications include facilitating the development of peptide-based therapeutics and probing biological pathways involving tyrosine and threonine residues.
  15. Dipeptide

    Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide that serves as a building block for peptide synthesis. It features a protected glutamic acid and a modified serine residue, allowing for the incorporation of stereochemical diversity in peptide design. This reagent is valuable in biological research aimed at investigating peptide interactions, functional studies, and developing novel therapeutic agents.
  16. Fmoc-Tyr(3-F,tBu)-OH Cyclic Peptide

    Fmoc-Tyr(3-F,tBu)-OH is an Fmoc-protected derivative of tyrosine, featuring a 3-fluoro and tert-butyl substitution. This compound serves as a valuable building block for the synthesis of cyclic peptides, facilitating the incorporation of functional modifications into peptide sequences. Its applications extend to studies involving structural biology and the development of peptide-based therapeutics.
  17. Dipeptide

    Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide featuring a protected tyrosine and a modified serine residue. This compound is primarily utilized for peptide synthesis and modification studies. Its unique structure enables researchers to explore the effects of different amino acid substitutions on peptide functionality and stability in biological systems. This reagent is suitable for applications in drug development, protein mimetics, and therapeutic peptide research.
  18. Dipeptide

    Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide that incorporates a protected asparagine and serine residue. This compound is designed for use in peptide synthesis and can aid in the development of peptide-based therapeutics. Its unique structure provides opportunities for studies involving protein folding and interactions, making it valuable in the field of medicinal chemistry and biochemistry research.
  19. Dipeptide

    Leucylproline is a dipeptide that modulates proteinase activity in a medium-dependent manner. This compound is of significant interest in biochemical research for its potential regulatory roles in protein metabolism and enzymatic functions. Its unique structure and biological activity make it a valuable tool for studies involving dipeptides and proteolytic enzymes.
  20. Nuclear localization peptide

    NHIP peptide is a nuclear localization peptide comprising 20 amino acids. It is predominantly expressed in neuronal-derived cells, such as LUHMES cells, and has been shown to promote the proliferation of 293T cells. NHIP peptide plays a significant role in regulating gene networks associated with neural development and autism spectrum disorder (ASD), making it valuable for research in neurobiology and related fields.
  21. dipeptide

    H-Asp-Ala-OH is a dipeptide comprised of aspartic acid and alanine. This compound can serve as a building block in peptide synthesis and is used in various biochemical assays to study protein interactions and cellular functions. Its unique structure allows researchers to investigate the effects of dipeptides on biological activity, making it valuable for studies in peptide-based drug discovery and development.
  22. Peptide

    Tat-GluR23Y, scrambled is a scrambled variant of the Tat-GluR23Y synthetic peptide. This peptide is designed to inhibit AMPA receptor (AMPAR) endocytosis, thereby contributing to the understanding of long-term depression (LTD) mechanisms in neural signaling. Researchers can utilize this reagent to study synaptic plasticity and related cognitive processes.
  23. Dipeptide

    Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide that incorporates a modified backbone structure. This compound is designed to facilitate peptide synthesis with enhanced stability and specificity in biological environments. It is primarily utilized in research applications focused on peptide engineering, drug delivery systems, and the study of peptide-receptor interactions.
  24. Polycationic Peptide

    Hexaarginine, a polycationic peptide composed of six arginine residues, acts predominantly through cell penetration mechanisms. This reagent is primarily utilized for the intracellular delivery of low-molecular-weight compounds, biomolecules, and particles, facilitating enhanced cellular uptake and distribution. Its efficacy in translocating various agents into cells makes it valuable for research applications in drug delivery and gene therapy.
  25. Polypeptide

    Fmoc-Thr(GalNAc(Ac)3-β-D)-OH is a polypeptide that primarily targets cancer-specific signaling pathways. This compound exhibits notable biological activity through the inhibition of cancer cell proliferation, while also enhancing the immune response. Its applications in research include investigating cellular mechanisms of cancer progression and immunotherapy development.
  26. Dipeptide

    Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide that features a unique psi (Me, Me) proline derivative. This compound serves as an important building block for peptide synthesis and can be used in the development of peptide-based therapeutics. Its structural modifications facilitate studies in various biological activities, including protein-protein interactions and enzyme activity modulation.
  27. Tripeptide

    H-Gly-Lys-Gly-OH is a tripeptide composed of glycine and lysine, which serves as a building block for various protein synthesis pathways. This reagent is particularly relevant in the study of casein and soybean protein synthesis, making it a valuable tool in biochemical research. Its unique sequence may also be of interest in exploring peptide function and interactions in biological systems.
  28. Dipeptide

    Fmoc-Val-Ser(psi(Me,Me)pro)-OH is a dipeptide that serves as a valuable building block for the synthesis of peptides and peptidomimetics. Its unique structure, featuring a psi(Me,Me)pro group, enhances conformational stability and bioactivity. This reagent is particularly useful in studies related to peptide design and optimization, as well as in the development of therapeutics targeting protein-protein interactions.
  29. Dipeptide

    Fmoc-Leu-Thr(psi(Me,Me)pro)-OH is a dipeptide characterized by the incorporation of a psi(Me,Me)proline moiety. This compound is utilized in peptide synthesis and can facilitate the study of peptide conformation and stability. Its unique structure makes it an important tool for examining protein interactions and developing peptide-based therapeutics.
  30. Synuclein-γ Inhibitor

    ANK peptide is a selective synuclein-γ (SNCG) inhibitor that effectively disrupts the interaction between SNCG and BubR1. This interference enhances the sensitivity of breast cancer cells to antimicrotubule agents, including nocodazole and paclitaxel. ANK peptide is valuable for research into cancer biology, particularly in understanding the molecular mechanisms of drug resistance in breast cancer.
  31. Lytic Peptide

    CyPep-1 is a cationic lytic peptide that exhibits significant antitumor activity. Its mechanism involves interaction with the negatively charged membranes of cancer cells, resulting in strong cytotoxic effects. CyPep-1 demonstrates potent cytolytic activity both in vivo and in vitro, making it a valuable tool for research applications focused on solid tumors.
  32. Dipeptide

    Fmoc-Leu-Ser(psi(Me,Me)pro)-OH is a synthetic dipeptide that incorporates an innovative psi-me(2)pro moiety. This compound serves as a valuable tool in peptide synthesis and exploration of protein interactions. Its unique structure enables researchers to investigate peptide conformation and stability, making it suitable for various applications in biomedical research and drug development.
  33. Polypeptide

    Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is a specialized polypeptide designed for use in fluorescence-based assays. This compound aids in tracking peptide interactions and localization within various biological systems due to its fluorescent properties. It is applicable in research areas focused on peptide synthesis, protein engineering, and cell imaging studies.
  34. Dipeptide

    Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH is a novel dipeptide with a focus on peptide synthesis. This compound exhibits significant potential for modulating protein interactions and enhancing peptide stability. It is particularly useful in the design of bioactive peptides and in studies that explore protein folding and aggregation. Researchers can utilize this compound for various applications in drug discovery and development, as well as in biochemical assays.
  35. Peptide Derivative

    Boc-Lys(Z)-OH (DCHA) is a peptide derivative primarily utilized in the synthesis of thymosin β4, βg, and β6 fragments. This compound has been shown to enhance E-rosette forming capacity in models of Lupus Nephritis. Additionally, Boc-Lys(Z)-OH (DCHA) serves as a reagent in the production of peptidyl thrombin inhibitors, contributing to various biochemical research applications.
  36. Peptide

    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met is a peptide sequence designed for biochemical research applications. This compound is utilized to study protein-protein interactions and enzymatic processes, and it may serve as a model for investigating peptide folding and stability. Its structural properties can facilitate the exploration of receptor binding and signaling pathways in various biological contexts.
  37. Dipeptide

    H-Met-Pro-OH is a dipeptide composed of methionine and proline. It serves as a substrate for the enzyme aminopeptidase P (APP) and plays a role in the activity of skin fibroblast prolidase. This reagent is valuable in studies related to peptide metabolism, enzymatic activity, and fibroblast function, making it suitable for a variety of biochemical and cellular research applications.
  38. Dipeptide

    Fmoc-Val-Thr(psi(Me,Me)pro)-OH is a dipeptide comprised of valine and threonine, modified with a psi(Me,Me)proline residue. This compound is utilized in peptide synthesis and can serve as a tool to study protein interactions and structure-activity relationships. Its structural features make it valuable for investigations in the fields of medicinal chemistry and peptide therapeutics.
  39. Methionine Dipeptide

    D-Met-Met is a methionine dipeptide that serves as an orally active compound, primarily involved in cellular metabolism and protein synthesis. This reagent exhibits key biological activity in promoting antioxidant defenses, potential neuroprotective effects, and supporting muscle recovery. D-Met-Met is applicable in research related to nutritional supplements, therapeutic development, and studies on amino acid metabolism.
  40. Dipeptide

    Glycyl-L-Proline TFA is a dipeptide composed of glycine and L-proline, primarily utilized in studies investigating the relationship between transmembrane potential and proton gradients in cellular transport mechanisms. This compound is valuable in research exploring intestinal absorption processes and can provide insights into peptide transport systems. Its unique structure facilitates investigations into the physiological roles of dipeptides in membrane dynamics and transport efficiency.
  41. Dipeptide

    Lysylcysteine is a dipeptide formed by the combination of lysine and cysteine. It has been shown to possess antioxidant properties and may influence cellular signaling pathways. This compound is primarily used in research related to protein structure, redox biology, and as a potential therapeutic agent in oxidative stress-related disorders.
  42. Dipeptide

    L-Phenylalanyl-L-glutamic acid is a dipeptide that serves as a high-affinity substrate for the peptide transporter PEPT2, demonstrated by a Ki value of 0.022 mM. In contrast, it exhibits a lower affinity for PEPT1, with a Ki value of 0.18 mM. This compound can be utilized in research focused on peptide transport mechanisms and their implications in pharmacology and drug delivery systems.
  43. Peptide Coupling Reagent

    HATU (Hexafluoro-2-(mercaptomethyl) pyridine) is a third-generation uronium salt employed as a peptide coupling reagent. It enhances the rate of peptide coupling reactions and activates amino acids, facilitating peptide bond formation in both solution-phase and solid-phase syntheses. Additionally, HATU supports peptide assembly, fragment coupling, and linear peptide cyclization. It is also effective in promoting N-acylation of chitosan to produce amide-linked cationic derivatives with a modifiable degree of substitution, making it a valuable tool in amine acylation processes.
  44. Peptide Coupling Additive

    Ethyl 2-cyano-2-(hydroxyimino)acetate serves as a peptide coupling additive, primarily functioning to suppress racemization during peptide synthesis. This compound enhances coupling efficiency in both solution-phase and solid-phase synthesis, making it a valuable tool in peptide chemistry. Its ability to promote higher yields and improve product purity underscores its significance in various biological research applications.
  45. Tripeptide

    Copper tripeptide (GHK-Cu) is a tripeptide known for its role as a natural modulator in skin regeneration. This compound enhances messenger RNA levels for critical extracellular matrix components such as collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Additionally, Copper tripeptide serves as a chemoattractant during wound healing, promoting the recruitment of inflammatory and endothelial cells, thus playing a vital role in tissue repair and regeneration. Its biological activities make it valuable for research applications focused on dermal health and regenerative medicine.
  46. Peptide Coupling Reagent

    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate functions as an effective peptide coupling reagent, facilitating the formation of peptide bonds between amino and carboxyl groups. This compound serves as a versatile BOP analog in peptide synthesis, promoting the efficient construction of various peptide compounds. Its application is essential in the development of peptide-based therapeutics and research in synthetic chemistry.
  47. Polypeptide

    INF7 is a derivative of the N-terminal domain of the HA2 protein that functions primarily as a polypeptide. It disrupts the stability of endosomal membranes through a mechanism that does not rely on membrane fusion, making it effective in enhancing the endosomal escape of complex or liposome-encapsulated proteins. This property allows for improved intracellular signaling and increased retention of molecular imaging probes when co-encapsulated with INF7 in liposomes, facilitating various biological research applications.
  48. Cross-Linked Peptide

    Azide-A-DSBSO crosslinker is a homobifunctional, azide-labeled crosslinking reagent that targets lysine residues through an NHS ester reaction. This membrane-permeable and acid-cleavable compound is particularly useful in cross-linking mass spectrometry (XL-MS) to investigate protein-protein interactions. Its mass spectrometry-cleavable properties enable efficient analysis of cross-linked complexes, facilitating deeper insights into protein dynamics and interactions in biological systems.
  49. Anticancer Peptide

    GE11 is an active anticancer peptide that serves as a smart carrier in colloidal drug delivery systems for antitumor agents. Its ability to selectively target cancer cells enhances the therapeutic efficacy of combined treatments. GE11 is valuable for research applications aimed at understanding tumor biology and developing innovative cancer therapies.
  50. Muscle Homing Peptide

    Muscle Homing Peptide M12 targets surface proteins on muscle cells, facilitating enhanced cellular uptake of nanoparticles within myoblasts in vitro. Its ability to bind specifically to muscle tissue makes it a valuable tool in drug delivery applications. Muscle Homing Peptide M12 can be covalently conjugated to PLGA-PEG nanoparticles through N-terminal α-amino groups using the N-hydroxysuccinimide ester reaction, thereby improving the localization and effectiveness of therapeutic agents in muscle tissues.

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