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ANK peptide

Catalog No.: A86275
Synuclein-γ Inhibitor
ANK peptide is a selective synuclein-γ (SNCG) inhibitor that effectively disrupts the interaction between SNCG and BubR1. This interference enhances the sensitivity of breast cancer cells to antimicrotubule agents, including nocodazole and paclitaxel. ANK peptide is valuable for research into cancer biology, particularly in understanding the molecular mechanisms of drug resistance in breast cancer.
ANK peptide 929207-58-9 Synuclein-γ Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionANK peptide is a selective synuclein-γ (SNCG) inhibitor that effectively disrupts the interaction between SNCG and BubR1. This interference enhances the sensitivity of breast cancer cells to antimicrotubule agents, including nocodazole and paclitaxel. ANK peptide is valuable for research into cancer biology, particularly in understanding the molecular mechanisms of drug resistance in breast cancer.
Product Information
Catalog NumA86275
FormulaC152H244N52O46S2
Molecular Weight3600.01
CAS Number929207-58-9
SequenceLys-Gly-Asn-Ser-Ala-Leu-His-Val-Ala-Ser-Gln-His-Gly-His-Leu-Gly-Cys-Ile-Gln-Thr-Leu-Val-Arg-Tyr-Gly-Ala-Asn-Val-Thr-Met-Gln-Asn-His-Gly
Sequence shorteningKGNSALHVASQHGHLGCIQTLVRYGANVTMQNHG
SMILES[C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCCCN)N)=O)=O)CC(N)=O)=O)CO)=O)C)=O)CC(C)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(NCC(N[C@@H](CC3=CN=CN3)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CN=CN5)C(NCC(O)=O)=O)=O)CC(N)=O)=O)CCC(N)=O)=O)CCSC)=O)[C@@H](C)O)=O)C(C)C)=O)CC(N)=O)=O)C)=O)=O)=O)CCCNC(=N)N)=O)C(C)C)=O)CC(C)C)=O)[C@@H](C)O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CS)=O)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)CO)=O)C)=O)C(C)C)=O
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