Catalog No.
Product Name
Application
Product Information
Citations
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Tyrosinase Inhibitor
Cysteine peptide is a potent tyrosinase inhibitor that exhibits skin-whitening, antioxidant, and multi-regulatory properties. By inhibiting tyrosinase activity and obstructing melanin transport, it effectively reduces UV-B-induced skin erythema and pigmentation. Additionally, cysteine peptide plays a role in skin health by scavenging reactive oxygen species (ROS), mitigating oxidative stress, and promoting pheomelanin synthesis. This compound also functions as a plant signaling factor, influencing vegetative growth, development, and responses to environmental stressors. -
Peptide
[Asp371]-Tyrosinase (369-377), human is a peptide derived from the human tyrosinase protein and is characterized as an HLA-A2.1-restricted epitope. This peptide plays a crucial role in the development of tumor-targeted vaccines aimed at eliciting specific immune responses against melanoma. It has been utilized in research applications focused on cancer immunotherapy and cellular immune response studies. -
Nonapeptide
Tyrosinase (192-200), human mouse is a nonapeptide that serves as a significant target for cytolytic T cells (CTL) via the HLA-B44 molecule. This peptide is crucial for studying immune responses in melanoma-associated cancers. Its role in T cell recognition makes it valuable for research applications focused on cancer immunotherapy and the development of targeted treatments. -
Antioxidant Peptide
Diaminopropionoyl tripeptide-33 is an antioxidant peptide that provides protection against UVA-induced DNA damage in skin cells. This bioactive compound is primarily used in cosmetic formulations to enhance skin cell resilience and promote healthier skin. Its application in research encompasses the study of skin aging and cellular defense mechanisms, making it a valuable component in the development of dermatological products. -
Bioactive Peptide
GAD65 (524-543) is a bioactive peptide derived from the glutamic acid decarboxylase 65 protein. This peptide fragment plays a crucial role in eliciting proliferative T cell responses in the non-obese diabetic (NOD) mouse model of autoimmune diabetes. It serves as a selective stimulus for the diabetogenic T cell clone BDC2.5, enhancing the susceptibility of NOD mice to type 1 diabetes when immunized with GAD65 (524-543). This reagent is valuable for research into T cell activation, autoimmune diabetes mechanisms, and potential therapeutic targets. -
Neuroprotective Peptide
Semax is a synthetic neuroprotective peptide that mimics the adrenocorticotropic hormone (ACTH) and is capable of penetrating the blood-brain barrier. This peptide exhibits notable immunomodulatory and nootropic properties, making it relevant for research into central nervous system disorders. Semax's potential applications include investigations into Alzheimer's disease and cerebral ischemia, where its neuroprotective effects may provide valuable insights. -
α-Peptide
Oligopeptide P11-4 is an α-peptide that self-assembles into β-sheet amyloids, exhibiting hydrogel characteristics at low pH. This oligopeptide demonstrates significant potential in biomimetic mineralization and enamel regeneration, making it applicable in oral care research and development. -
Abeta Degrader
β-Sheet Breaker Peptide iAβ5 is a potent degrader of amyloid-β (Aβ) oligomers, specifically targeting the β-sheet conformation responsible for its aggregation in Alzheimer's disease. This peptide effectively promotes the degradation of fibrillar amyloid deposits in vivo, thereby mitigating the neurotoxic effects associated with Aβ. Additionally, β-Sheet Breaker Peptide iAβ5 can reduce the size and quantity of amyloid plaques while decreasing the activation of IL-1β-positive microglial cells surrounding these deposits. The incorporation of a hydrophobic benzyl alcohol (HBA) tag enables visual detection under acidic conditions, facilitating quantitative analysis in relevant research applications. -
β-Amyloid Peptide Fragment
β-Amyloid (31-35) is a peptide fragment derived from the native Amyloid-β peptide, specifically representing the shortest sequence that maintains neurotoxic functionality. This compound is primarily utilized in research focused on neurodegenerative diseases, particularly Alzheimer's disease, where it aids in the investigation of amyloid plaques and their impact on neuronal health. Its bioactivity makes it a valuable tool for understanding the mechanisms underlying neurotoxicity and for evaluating therapeutic strategies. -
dipeptide
Ile-Phe is a dipeptide known for its ability to self-associate in aqueous solutions, forming a transparent thermoreversible gel through a network of fibrillar nanostructures. This self-assembly property may play a role in biological processes involving amyloid formation and other protein aggregation phenomena. It serves as a valuable tool for studying peptide interactions and the mechanics of gel formation in various biochemical applications. -
Amyloid-β Peptide
β-Amyloid (1-28) is a fragment of the amyloid-β peptide, primarily recognized for its role in metal ion binding. This peptide is significant in the formation of amyloid plaques associated with Alzheimer's disease (AD), making it a critical target for research into AD pathogenesis and potential therapeutic interventions. It is valuable for studies investigating the biochemical pathways involved in neurodegeneration and the development of amyloid-targeting strategies. -
FITC Tagged Aβ1-42 Peptide
FITC-β-Ala-Amyloid β-Protein (1-42) is a fluorescein isothiocyanate (FITC) tagged version of the Aβ1-42 peptide. This peptide is critical in the study of Alzheimer’s disease, as it is involved in the formation of amyloid plaques that are characteristic of the condition. FITC labeling enhances its detectability in various assay formats, making it suitable for studies on peptide aggregation, interaction with receptors, and screening of compounds in Alzheimer's research. -
Amyloid-β Peptide Fragment
β-Amyloid (29-40) is a peptide fragment derived from the Amyloid-β peptide, specifically encompassing amino acids 29 to 40. This fragment plays a significant role in Alzheimer's disease research, as it contributes to the understanding of amyloid plaque formation and neurodegeneration. Its biological activity includes interactions with cellular receptors and modulation of neuroinflammatory responses, making it useful for studying mechanisms of synaptic dysfunction and potential therapeutic interventions in neurodegenerative disorders. -
Aβ Peptide
β-Amyloid (1-38) is a peptide that targets the aggregation of amyloid-beta (Aβ), primarily influencing the conversion of Aβ(1-42) to β-sheet-rich structures. This compound has been shown to reverse the detrimental effects of Aβ(1-42) on long-term potentiation in acute hippocampal slices and enhance membrane conductance in primary neuronal cultures. Additionally, β-Amyloid (1-38) alleviates Aβ(1-42)-related phenotypic changes in Caenorhabditis elegans, making it a valuable tool for research into Alzheimer’s disease and related neurodegenerative processes. -
Polypeptide
(Asp37)-Amyloid β-Protein (1-42) is a G37D mutant variant of the wild-type Amyloid-beta (1-42) peptide, which plays a crucial role in Alzheimer's disease pathology. This modified polypeptide is utilized in research studies investigating protein aggregation, neurotoxicity, and the mechanisms underlying amyloid plaque formation. Its unique properties make it an important tool for examining the functional consequences of mutations within the Amyloid-beta sequence. -
Amyloid-β Peptide
β-Amyloid (15-21) is a peptide fragment derived from the Amyloid-β peptide, primarily targeting amyloid aggregation pathways. It is essential for the study of Alzheimer's disease mechanisms and the investigation of neurodegenerative processes associated with amyloid pathology. This reagent aids in elucidating the role of amyloid plaques in neuronal toxicity and offers insights into potential therapeutic interventions. -
Bioactive Peptide
[D-Ser14]-Humanin is a modified bioactive peptide targeting amyloid-β fibrillation. This D-form variant exhibits enhanced protective effects against oxidative stress and cellular death compared to its L-form counterpart, Humanin. Its potent inhibitory activity makes [D-Ser14]-Humanin a valuable tool in Alzheimer's disease research, particularly in studies focused on amyloid-related neurotoxicity and cellular resilience. -
Bioactive Peptide
Biotin-Ahx-β-Amyloid (1-40) is a biotinylated bioactive peptide that targets amyloid-beta, a key component implicated in Alzheimer's disease pathology. This compound facilitates the study of amyloid aggregation and provides valuable insights into the mechanisms of neurodegeneration. Research applications include the exploration of amyloid-beta's role in cellular toxicity and the development of therapeutic strategies for Alzheimer's disease. -
Oligopeptide Capable Of Self-assembling Into Nanotubes
AAKLVFF is an oligopeptide known for its ability to self-assemble into nanotubes. It is derived from the core section of β-amyloid and serves as a methanol-compatible liquid crystal alignment medium, facilitating residual dipolar coupling measurements. This property enhances its application in structural studies of protein interactions and dynamics, making it a valuable tool in biochemical and biophysical research. -
Bioactive Peptide
Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 is a bioactive peptide designed as a substrate for matrix metalloproteinases (MMPs). This compound exhibits specific enzymatic activity that facilitates studies on MMP-mediated processes, such as tissue remodeling and extracellular matrix degradation. It serves as a valuable tool in research applications focused on cancer metastasis, wound healing, and various inflammatory conditions linked to MMP activity. -
Tripeptide
Lysyl-phenylalanyl-lysine is a tripeptide that effectively activates LAP-TGF-β1, facilitating the release of active TGF-β1. This compound plays a crucial role in regulating the expression of matrix metalloproteinases (MMPs), thus contributing to the modulation of tissue remodeling processes. Lysyl-phenylalanyl-lysine is valuable for research into skin aging-related diseases and impaired wound healing mechanisms. -
Cross-Linked Peptide
C-telopeptide is a cross-linked peptide derived from type I collagen, released during the process of bone resorption. It serves as a valuable biomarker for assessing bone health, as its levels correlate with bone mineral density (BMD). This reagent is essential for research applications focused on osteoporosis, bone metabolism, and related pathologies. -
Bioactive Peptide
Noxa A BH3 is a bioactive peptide that corresponds to the BH3 domain of the Noxa protein. This peptide is known to induce apoptosis through its interaction with pro-survival Bcl-2 proteins, thereby promoting cell death in cancer cells. It serves as a valuable tool for research in apoptosis mechanisms and therapeutic development targeting Bcl-2 family proteins. -
Bioactive Peptide
Noxa B BH3 is a bioactive peptide that targets the BH3 domain of the Noxa protein. It plays a crucial role in regulating apoptosis by promoting mitochondrial outer membrane permeabilization. This peptide is useful for studying cellular mechanisms of programmed cell death and exploring potential therapeutic interventions in cancer and other diseases associated with dysregulated apoptosis. -
Tetrapeptide
[Des-Tyr1]-Met-Enkephalin is a tetrapeptide that serves as a degradation product of enkephalins. This compound is primarily known for its role in modulating pain and providing analgesic effects through interactions with opioid receptors. It is utilized in research applications focused on pain management, neurobiology, and the study of endogenous peptide systems. -
Chromogenic Peptide Substrate
H-Gly-Glu-pNA is a chromogenic peptide substrate primarily utilized for enzymatic analysis, specifically in the detection of trypsin and urokinase-type plasminogen activator (uPA). This substrate allows for the sensitive measurement of enzymatic activity, facilitating research in areas such as proteolytic enzyme studies, clinical diagnostics, and biochemical assay development. Its ability to produce a measurable chromogenic signal makes it an essential tool for researchers investigating protease activity and related biological processes. -
Beauty Peptide
Acetyl hexapeptide-38 is a beauty peptide that enhances tissue repair by targeting fibroblasts in the dermis. Its primary mechanism involves promoting collagen synthesis and thickening subcutaneous fat, facilitating the skin's natural repair processes. Key biological activities include increasing collagen content and improving skin tissue structure, making it useful in cosmetic applications such as repairing congenital soft tissue defects, reducing tear grooves and nasolabial folds, and minimizing postoperative scars. This peptide is also applicable in micro-plastic surgery for skin tissue enhancement. -
Dipeptide
Prolylisoleucine (Pro-Ile) is a dipeptide consisting of proline and isoleucine, primarily known for its ability to inhibit endopeptidase 24.16. This compound exhibits significant biological activity by modulating peptide metabolism, making it a valuable tool in research focused on neuropeptide regulation and enzymatic pathways. Prolylisoleucine can be utilized in studies investigating the roles of neuropeptides in various physiological processes. -
Peptide-AMC Linked Substrate
Z-Leu-Leu-Glu-AMC is a peptide-AMC linked substrate designed to assess the hydrolytic activity of the proteasome. This compound is particularly useful in studies related to Parkinson's disease, enabling researchers to investigate the enzyme's role in protein degradation and cellular homeostasis. Its application facilitates the understanding of proteasome dysfunction in neurodegenerative disorders. -
Proteasome-Activating Peptide
Proteasome-activating peptide 1 is a peptide that enhances chymotrypsin-like activity of the proteasome, thereby increasing proteolytic rates in vitro and in cellular cultures. This compound plays a significant role in preventing protein aggregation, demonstrated in cellular models of amyotrophic lateral sclerosis. Its ability to modulate proteasomal activity makes it a valuable tool for research into neurodegenerative diseases and protein homeostasis. -
Bioactive Peptide
Calpastatin subdomain B is a bioactive peptide that specifically inhibits calpain activity. By effectively regulating calpain, this peptide plays a crucial role in cellular processes such as apoptosis, muscle contraction, and neuronal signaling. It is widely used in research applications involving proteolytic regulation and the study of calpain-related diseases. -
Peptide Substrate
Z-Gly-Gly-Arg-βNA is a synthetic peptide substrate designed to target trypsin-like activities within the proteasome. This substrate is utilized for studying proteolytic processes and enzyme kinetics, facilitating research on protein degradation and regulation. Its chemical structure allows for specific interactions with proteasomal active sites, making it an essential tool for investigating cellular mechanisms related to proteostasis and stress responses. -
Bioactive Peptide
Renin inhibitor peptide, rat is a biologically active peptide that specifically inhibits renin, an enzyme involved in the regulation of blood pressure and electrolyte balance. This peptide serves as a valuable tool for studying the renin-angiotensin system and its implications in cardiovascular research. Its application in experimental models can aid in the investigation of hypertension and related disorders. -
Renin Antagonist
Handle region peptide, rat is a prorenin receptor antagonist that effectively inhibits the activation of prorenin, thereby mitigating the progression of diabetic nephropathy. This compound demonstrates significant anti-inflammatory properties, particularly within ocular tissues. Its applications extend to research on renal disease models and ocular inflammation, providing valuable insights into therapeutic interventions for these conditions. -
Oligopeptide Renin Inhibitor
PD 125967 is an oligopeptide renin inhibitor that specifically targets the renin-angiotensin system. It exhibits significant activity in lowering blood pressure, making it a valuable tool for cardiovascular research. This compound is useful for studying hypertension and related disorders, providing insights into the regulation of blood pressure through renin inhibition. -
EphA4 Antagonist
KYL peptide is an EphA4 antagonist that selectively inhibits the EphA4 receptor, demonstrating an IC50 of 4.22 μM and a Kd of 1.3 μM. By binding to the ligand-binding domain of EphA4, KYL peptide effectively mitigates Aβ-induced synaptic dysfunction and enhances synaptic plasticity in models of Alzheimer's disease. Additionally, this peptide may facilitate nerve regeneration following injury and has potential applications in modulating immune responses. -
Syk
Syk Kinase Peptide Substrate is a specific peptide substrate designed for Syk kinase activity assays. This substrate enables researchers to study the phosphorylation activity of Syk kinase, which plays a critical role in immune response and signaling pathways. It is useful for applications involving signal transduction research and the investigation of Syk-related diseases. -
Synthetic Natriuretic/Vasorelaxing Peptide
Vasonatrin Peptide (VNP) is a synthetic chimera that combines the properties of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). It exhibits vasorelaxing effects, including enhanced venodilation typical of CNP and natriuretic activity associated with ANP, along with unique arterial vasodilating effects. VNP has been shown to protect against ischemia-reperfusion injury in diabetic models by modulating ER stress through the cGMP-PKG signaling pathway, making it a valuable tool for cardiovascular research. -
Synthetic Peptide
BPDEtide is a synthetic peptide designed as a selective substrate for cyclic guanosine monophosphate-dependent protein kinase (cGK) and cyclic adenosine monophosphate-dependent protein kinase (cAK). It demonstrates apparent Km values of 68 μM for cGK and 320 μM for cAK, highlighting its specificity for cGK activity measurement. This compound is valuable for studying cGK signaling pathways and assessing kinase activity in various biological research applications. -
G Substrate Peptide
G-Subtide is a G-substrate peptide that specifically targets Purkinje cells within the cerebellum. It serves as a preferred phosphorylation substrate for recombinant PfPKG2 protein, demonstrating limited activity outside of background levels. This reagent is useful for studying signaling pathways involving protein kinases and understanding cerebellar function at a molecular level. -
Syntenin Peptide Inhibitor
KSL 128114 is a potent peptide inhibitor of syntenin, targeting the PDZ1 domain with nanomolar affinity. This compound exhibits stability in human plasma and mouse hepatic microsomes, making it suitable for in vitro and in vivo studies. KSL 128114 demonstrates selective inhibition of syntenin, providing valuable insights into cellular signaling pathways and potential therapeutic applications in disorders associated with syntenin dysregulation. -
Cell Adhesion Peptide
H-Tyr-Ile-Gly-Ser-Arg-NH2 is a cell adhesion peptide that plays a crucial role in mediating cell adhesion and receptor interactions. This hexapeptide, derived from laminin, enhances epithelial cell adhesion properties, making it a valuable tool for studies in tissue engineering, cell migration, and regenerative medicine. Its ability to promote cell attachment and function makes it an important reagent for researchers investigating cellular behaviors in various biological contexts. -
Wound Healing Peptide
Tiger17 is a wound healing peptide that promotes tissue repair through the regulation of TGF-β1 secretion. It activates the Smad signaling pathway, specifically enhancing the phosphorylation of Smad2 and Smad3, which are crucial for cellular processes involved in wound healing. This peptide is valuable for research focused on tissue regeneration and therapeutic strategies for improving wound recovery. -
LSKL Control Peptide
SLLK is a control peptide for the LSKL sequence, serving as an essential tool in studies investigating Thrombospondin-1 (TSP1) inhibition. This peptide facilitates the evaluation of TSP1-related biological pathways and interactions, aiding in the understanding of angiogenesis and tissue repair processes. Its application is crucial in various research settings, including wound healing, cancer biology, and vascular biology. -
Pentapeptide
H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide that promotes cell adhesion through its specific domain. This sequence is known to interact with the thrombospondin-1 (TS1) receptor, facilitating various biological processes. Applications of H-ILE-ARG-VAL-VAL-MET-OH include studies on cell signaling, tissue engineering, and investigating the role of extracellular matrix components in cellular dynamics. -
Control Peptide
L-Seryl-L-leucyl-L-leucyl-L-lysine (SLLK) is a control peptide used in research applications to validate experimental results involving LSKL. This peptide serves as a reference to distinguish specific biological activity when investigating peptide interactions and effects. SLLK is essential for studies focusing on peptide functionality, binding assays, and exploring cellular responses in various biological contexts. -
ACTH Peptide
Acetyl-ACTH (2-24) is a peptide fragment derived from proopiomelanocortin (POMC) that targets the adrenocorticotropic hormone (ACTH) pathway. This peptide exhibits potent biological activity as an agonist at the melanocortin-1 (MC-1) receptor, influencing various physiological processes related to stress response and pigmentation. It is applicable in studies investigating the role of ACTH in hormonal regulation, obesity, and metabolic disorders, making it a valuable tool in endocrine research. -
ACTH Peptide
Acetyl-ACTH (3-24) is a synthetic peptide derived from proopiomelanocortin (POMC), specifically acting on the adrenocorticotrophic hormone (ACTH) pathway. This fragment plays a pivotal role as an agonist at the melanocortin-1 receptor (MC-1), influencing various physiological processes. Acetyl-ACTH (3-24) is utilized in research applications exploring stress response, skin pigmentation, and metabolic regulation. It serves as a valuable tool for studies related to the biological actions of melanocortin peptides. -
Coactivator-derived Mimic
SRC2-2 peptide is a coactivator-derived mimic that targets the androgen receptor (AR) ligand. It plays a vital role in modulating AR activity, making it a valuable tool for investigating mechanisms of prostate cancer progression and treatment. This peptide is suitable for studies focused on AR signaling pathways and the development of AR-targeted therapies. -
Atrial Natriuretic Peptide
Atriopeptin I (rat, mouse) is an atrial natriuretic peptide that primarily targets the regulation of cardiovascular homeostasis. It is known to stimulate testosterone production, exhibiting a half-maximum stimulation concentration of 38 nM. This reagent is valuable for research applications related to endocrine regulation and cardiovascular function, providing insights into physiological responses and potential therapeutic targets.
