Catalog No.
Product Name
Application
Product Information
Citations
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Y5 Receptor Agonist
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective agonist for the neuropeptide Y Y5 receptor, exhibiting an IC50 of 0.24 nM for binding to the human Y5 receptor. This compound significantly stimulates food intake, making it valuable for research into appetite regulation and metabolic disorders. Its specific activity at the Y5 receptor allows for targeted investigations into neuropeptide signaling pathways and their implications in obesity and other related conditions. -
Neuropeptide S Receptor (NPSR) Antagonist
RTI-118 is a small-molecule antagonist of the neuropeptide S receptor (NPSR). This compound has demonstrated potential in mitigating addiction behaviors, including a selective reduction in self-administration of addictive agents. RTI-118 serves as a valuable tool for research investigating the role of NPSR in addiction and related neuropharmacological pathways. -
NPY Cardiac Receptor Antagonist
Neuropeptide Y (18-36) (porcine) serves as a competitive antagonist of neuropeptide Y (NPY) cardiac receptors. With an IC50 value of 158 nM and a Ki value of 140 nM, this compound effectively inhibits the binding of I-NPY to cardiac ventricular membranes in a concentration-dependent manner. It is a valuable reagent for research focused on the pathophysiology and therapeutic interventions in congestive heart failure. -
Neuropeptide
Capa-2 is a neuropeptide that primarily targets calcium ion channels. It activates calcium ion influx, stimulates nitric oxide (NO) production, and activates soluble guanylate cyclase (sGC), resulting in elevated intracellular cGMP levels. This compound plays a crucial role in regulating ion and fluid secretion and is valuable in research focusing on diuresis and renal function. -
Endogenous Peptide Hormone
Uroguanylin (human) is an endogenous peptide hormone that acts as a natural ligand for the Guanylyl Cyclase receptor. This compound exhibits significant anti-tumor activity, particularly in the context of metastatic colorectal cancer. Uroguanylin (human) serves as a valuable tool for research applications focused on cancer biology and the exploration of signaling pathways related to gastrointestinal tumors. -
Eyelash Growth Stimulator
Myristoyl pentapeptide-17 acetate is a potent eyelash growth stimulator that enhances keratin production. This compound facilitates the delivery of essential components in serums, including growth factors and lysophosphatidic acid, promoting healthy eyelash development. Its application in cosmetic research underscores its potential in hair follicle biology and regenerative therapies for enhancing eyelash length and density. -
Eyelash Growth Stimulator
Myristoyl pentapeptide-17 is a peptide compound that stimulates eyelash growth primarily by enhancing keratin production. This reagent facilitates the delivery of essential growth factors and lysophosphatidic acid present in formulations, supporting hair follicle health and elongation. Its applications include cosmetic research on eyelash enhancement and the development of formulations targeting hair growth. -
mAChR Antagonist
Dipeptide diaminobutyroyl benzylamide diacetate functions as a muscarinic acetylcholine receptor (mAChR) antagonist. It induces muscle relaxation, making it relevant in studies related to skin aging and facial wrinkles, including crow's feet and periorbital creases. This compound can be utilized in research focused on dermatological applications and the physiological mechanisms underlying muscle tone regulation in the skin. -
Neuropeptide
KEMPFPKYPVEP is a 12-amino acid neuropeptide that targets neuropeptide receptors to enhance the levels of dopamine (DA) and norepinephrine (NE) in the prefrontal cortex. This compound has been shown to promote spatial and object recognition memory in mouse models of amnesia induced by Scopolamine. It serves as a valuable tool for research into cognitive enhancement and the underlying mechanisms of memory function. -
Peptide Hormone
Atrial natriuretic peptide (3-28) (human) is a peptide hormone primarily synthesized and secreted by the atrial myocardium. This bioactive peptide plays a critical role in the regulation of blood pressure, fluid balance, and electrolyte homeostasis. Research applications include studies on cardiovascular function, renal physiology, and the modulation of neurohormonal pathways. -
Peptide
Big endothelin-3 (Human, 1-41 amide) serves as a precursor molecule to the bioactive peptide Endothelin-3 (ET-3), consisting of 41 amino acids. This peptide is primarily involved in vasoconstriction and regulation of vascular tone. Its applications extend to studying cardiovascular function, understanding cellular signaling pathways, and exploring potential therapeutic targets in hypertension and heart failure research. -
Vasoactive Peptide
[Ala2] Endothelin-3 (ET-3) is a vasoactive peptide analog of endothelin-3, featuring alanine substitutions for cysteine residues. This peptide is primarily produced by human rhabdomyosarcoma cell lines and plays a crucial role in paracrine signaling by promoting endothelial cell migration. Research applications include studies on vascular biology, endothelial function, and the pathophysiology of muscle-origin tumors. -
B lymphocyte mitogen/polyclonal Activator
Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is a synthetic N-terminal analog of E. coli outer membrane lipoproteins that serves as a potent B lymphocyte mitogen and polyclonal activator. It plays a critical role in stimulating B cell proliferation and differentiation, making it valuable in the study of immune adjuvants. This reagent is useful for investigating immune responses and developing immunotherapeutic strategies. -
Bioactive Peptide
p70 S6 Kinase substrate is a bioactive peptide that serves as a specific substrate for p70 ribosomal S6 kinase (S6K). This peptide plays a critical role in cellular signaling pathways, particularly in protein synthesis and cell growth regulation. It is widely utilized in research applications focused on the mechanistic understanding of mTOR signaling and related cellular processes. -
Lamin Kinase
S6 peptide is a significant substrate of lamin kinase, playing a crucial role in cardiac hypertrophy induced by mechanical loading. This peptide is activated by various growth factors, making it a valuable tool for studying cellular signaling pathways related to cardiac remodeling and hypertrophic responses. Its use in research can enhance the understanding of mechanisms underlying cardiovascular diseases and developmental processes. -
Neuroprotective Peptide
TAT-EE3 is a neuroprotective peptide that disrupts the interaction between TRPM2 and N-methyl-D-aspartate receptors (NMDARs). By inhibiting TRPM2-induced increases in NMDAR surface expression and current amplitude, TAT-EE3 offers protective effects against neuronal damage. This reagent serves as an important tool for research focused on ischemic injury and related conditions, including the study of ischemic stroke both in vitro and in vivo. -
Modified TAT-CBD3 Peptide
TAT-CBD3A6K is a modified TAT-CBD3 peptide that primarily targets voltage-dependent calcium channels. This compound effectively reduces T- and R-type calcium currents in dorsal root ganglion (DRG) neurons, demonstrating notable anti-nociceptive properties. TAT-CBD3A6K has been shown to mitigate pain in a model of AIDS-induced peripheral neuropathy by preventing the CRMP-2-mediated enhancement of T- and R-type calcium channel activity, making it a valuable tool for studying pain mechanisms and peripheral neuropathy interventions. -
Depolarizing Agent
Mast cell degranulating peptide (28-49) is a depolarizing agent derived from bee venom that acts on mast cells to induce degranulation. It has been shown to elevate cyclic guanosine monophosphate (cGMP) levels in mouse cerebellar slices, implicating its role in modulating neurotransmission and signaling pathways. This peptide is valuable for research applications focused on mast cell biology and the study of neuropharmacological effects. -
Neuropeptide
YMRF-NH2 is a neuropeptide that specifically targets the FMRFa receptor (FMRFa-R), exhibiting an EC50 value of 31 nM. This compound plays a critical role in neurobiology, particularly in studies related to neuropeptide signaling pathways. YMRF-NH2 is valuable for research focusing on neurotransmission and the physiological effects of neuropeptides. -
Proatherosclerotic Peptide Hormone
GIP (22-51) human is a potent proatherosclerotic peptide hormone targeting the NF-κB signaling pathway. This 30-amino acid peptide promotes the expression of matrix metalloproteinase-8 (MMP-8) and induces proinflammatory and proatherosclerotic protein expression. Additionally, GIP (22-51) human elevates intracellular free calcium levels in THP-1-derived macrophages, making it a valuable tool for atherosclerosis research. -
Satiety Signaling Neuropeptide
Perisulfakinin is a satiety signaling neuropeptide that targets central nervous system pathways. It plays a crucial role in regulating appetite and energy balance by inhibiting the activity of neurons that promote general activity. This compound is valuable for research applications focused on understanding food intake regulation, metabolic processes, and neuropeptide functions in the context of obesity and related disorders. -
Antiwrinkle Peptide
Argireline acetate, also known as Acetyl hexapeptide-3 acetate, is a non-toxic peptide designed to target the neuromuscular junction by significantly inhibiting Ca2+-dependent neurotransmitter release, primarily acetylcholine. This mechanism leads to its notable antiwrinkle and anti-aging effects, making it valuable in cosmetic research focused on skin rejuvenation and wrinkle reduction. Further investigations can explore its applications in dermatological and cosmetic formulations aimed at improving skin texture and appearance. -
Sperm Activating Peptide
Ser-Ala-alloresact is a sperm activating peptide (SAP) that facilitates the initiation of sperm motility and fertilization processes. This peptide originates from the eggs of marine invertebrates, where it plays a crucial role in enhancing sperm activation and promoting successful fertilization events. Researchers can utilize Ser-Ala-alloresact to explore mechanisms of fertilization and assess sperm function, providing insights into reproductive biology and potential fertility treatments. -
Anorexigenic Neuropeptide
LPLRF-NH2 is an anorexigenic neuropeptide that functions as a member of the RFamide peptide family. It has demonstrated the ability to increase arterial blood pressure and modulate the electrical activity of brainstem neurons. This compound is valuable for research applications focusing on appetite regulation and central nervous system signaling pathways. -
Peptide Ligand for GABARAP
K1 peptide is a high-affinity ligand for GABAA receptor-associated protein (GABARAP). It plays a crucial role in mediating protein interactions involved in cellular processes such as autophagy and synaptic transmission. K1 peptide is valuable for research applications focused on GABARAP function and its implications in neurobiology and cellular signaling pathways. -
Peptide
Octadecaneuropeptide is an 18-residue peptide that functions as a ligand for the gamma-aminobutyric acid (GABA) receptor's regulatory site, which is modulated by beta-carbolines. This peptide demonstrates significant biological activity by facilitating the punishment-induced suppression of drinking behavior in a dose-dependent manner. It serves as a valuable research tool for investigating GABAergic transmission and its implications in behavioral studies and neuropharmacology. -
Peptide Fragment
Leptin (22-56), human is a peptide fragment that plays a critical role in energy homeostasis and appetite regulation, interacting with various isoforms of leptin receptors (Ob-Rs). This fragment can be utilized in research applications focused on obesity, metabolic disorders, and endocrine signaling pathways. Its ability to influence signaling contributes to the understanding of leptin’s physiological effects and therapeutic potential in weight-related conditions. -
NCED3 Inducer
CLE25 peptide functions as an inducer of NCED3, facilitating the transport from roots to leaves and modulating NCED3 expression in conjunction with receptor-like kinases BAM1 and BAM3. This peptide promotes stomatal closure by influencing abscisic acid accumulation, thereby enhancing plant resistance to dehydration stress. It serves as a valuable tool in research related to plant stress responses and water regulation mechanisms. -
Tripeptide
H-Gly-Gly-Tyr-OH is a tripeptide known for its involvement in various biochemical pathways. This compound serves as a valuable tool in pharmaceutical research and biochemistry, contributing to the understanding of peptide interactions and biological functions. It may also be utilized in studies related to drug design and therapeutic development. -
Peptide
LSD is a peptide that specifically targets lymphatics associated with C8161 melanoma, demonstrating no binding affinity for normal tissues or tumor blood vessels. When conjugated with pro-apoptotic peptides, LSD effectively decreases the presence of tumor lymphatics. This compound is valuable for research in targeted therapies and the diagnostic evaluation of tumor lymphatics. -
Active Peptide
[Tyr8]-Substance P is an active peptide that functions primarily as a neuropeptide involved in pain perception and inflammation. This peptide is instrumental in studying receptor interactions and signal transduction pathways associated with neurogenic inflammation. Its biological activity makes it a valuable tool in neurological research and the investigation of pain-related disorders. -
Dipeptide
Fmoc-Gly-Gly-OSu is a dipeptide that serves as a valuable building block for the synthesis of antibody-drug conjugate (ADC) linkers. Its structural properties facilitate the formation of stable linkages, essential for effective delivery of therapeutic agents. This reagent is particularly useful in bioconjugation studies and in the development of targeted cancer therapies. -
Linear Dipeptide
H-Ile-Ala-OH, a linear dipeptide consisting of L-Isoleucine and L-Alanine, acts as a self-reactive cyclization reagent, demonstrating the ability to self-assemble into amorphous films or spherical structures in specific solvents. This compound serves as a precursor for the synthesis of cyclic peptides, such as cyclo (L-Isoleucyl-L-Alanine). Notably, H-Ile-Ala-OH undergoes solid-state cyclization at temperatures exceeding 206 °C, with initiation temperature influenced by side-chain substituent sizes. Its unique properties make it valuable in peptide research and materials science applications. -
Tool Peptide
BIMAX1 is a tool peptide designed to investigate the interaction between RBBP4 and importin β1, focusing on its role in the nuclear import pathway. This peptide facilitates studies on RBBP4's regulation of nuclear import efficiency, as well as its implications in cellular senescence. Its use in biochemical assays enhances the understanding of nucleocytoplasmic transport dynamics and cellular aging processes. -
CTL Peptide
OVA (241-270) is a non-specific cytotoxic T lymphocyte (CTL) peptide derived from the ovalbumin antigen. This peptide is instrumental in the study of T cell responses and is commonly utilized in immunological research to investigate CTL activation and functionality. Its application is particularly relevant in the context of vaccination and cancer immunotherapy research, aiding in the development of immune-modulatory strategies. -
Silica-precipitating Activity Peptide
R5 peptide is a silica-precipitating activity peptide derived from Cylindrotheca fusiformis. It exhibits the ability to induce silica precipitation, making it useful for studies involving biomineralization processes. This peptide can be applied in research focusing on silica-based materials and their interactions in biological systems. -
Peptide
5-Oxoprolyltryptophan is a peptide that serves as a model substrate for studying serotonin biosynthesis in the brain. This compound facilitates research into metabolic pathways related to neurotransmitter synthesis and offers insights into serotonin's role in neurological functions. Its application in biochemical assays makes it a valuable tool for investigating neuropharmacological effects. -
Peptide
Talovirtide is a peptide that incorporates L-valyl, functioning as a versatile research tool in the study of peptide biology and protein interactions. Its unique structural features facilitate investigations into cellular signaling pathways and therapeutic applications. Talovirtide is particularly valuable in the development of novel peptides for drug discovery and studying peptide-receptor interactions. -
CAQK Peptide Control
CGGK is a control peptide designed for use with the CAQK peptide. It serves as a vital tool in research applications involving peptide interactions and signaling pathways. CGGK aids in the validation and characterization of CAQK-related biological functions, enhancing the understanding of peptide-mediated processes in various experimental setups. -
Control Peptide for c(RGDyK)
Cyclo(Arg-Ala-Asp-(D-Tyr)-Lys) is a control peptide specifically designed for use with c(RGDyK). This cyclic peptide serves as a tool for studying integrin receptor interactions and cell adhesion processes. Its unique composition allows for comparative research with RGD-based peptides, providing insights into cellular signaling pathways and potential therapeutic applications in cancer and tissue engineering research. -
Peptide
NFLINETAR is a peptide derived from egg proteins, serving as a specific marker for the detection of egg allergens. Its application in ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) enables precise identification and quantification of egg allergens in various samples. This makes NFLINETAR a valuable tool for research in allergen characterization and food safety assessments. -
Peptide
RPFYSNAPQEIFIQQGR is a peptide derived from peanut proteins, serving as a specific marker for the detection of peanut allergens. Its unique sequence enables its use in advanced analytical techniques such as UHPLC-MS/MS, facilitating precise identification and quantification of peanut allergens in various samples. This peptide is essential for research applications focused on food safety, allergen detection, and immunological studies related to peanut allergies. -
Peptide Substrate
Suc-Phe-Leu-Phe-4MβNA is a fluorescent peptide substrate primarily used for the detection and quantification of proteolytic activity. This compound serves as an effective tool for research applications involving proteases, enabling the study of enzymatic mechanisms and dynamics in various biological processes. Its fluorescent properties facilitate real-time monitoring and analysis, making it valuable in biochemical assays and drug discovery research. -
Tumor Targeting Peptide
LS10 is a tumor-targeting peptide that specifically binds to the NG2 protein, serving as a functional ligand for targeted drug delivery to glioma. NG2 is predominantly overexpressed in glioma cells, while its expression is limited in normal tissues, making LS10 a valuable tool for precise therapeutic applications in glioma treatment and research. -
Peptide
YLLDLLPAAASHR is a peptide derived from egg proteins and serves as a specific marker for egg allergens. Its primary mechanism involves the detection of allergens through advanced analytical techniques such as UHPLC-MS/MS. This peptide is essential for research applications aimed at studying food allergies, particularly in the context of egg protein sensitization and its implications in immunological studies. -
Peptide
Prepro-von Willebrand factor (641-650) (bovine) is a peptide fragment derived from the Prepro-von Willebrand factor protein, exhibiting a specific binding affinity for type I collagen. This binding is crucial for vascular biology studies, particularly in understanding platelet adhesion and aggregation processes. The peptide can be utilized in research focused on hemostasis, thrombosis, and other cardiovascular conditions where von Willebrand factor plays a significant role. -
Neuropeptide
Small cardioactive peptide A (SCPA) is a neuropeptide derived from Aplysia that primarily modulates cardiac function. It exhibits significant biological activity in regulating heart rate and contractility, making it valuable for studies on cardiac physiology and neurobiology. SCPA is primarily utilized in research applications exploring neuropeptide signaling pathways and their effects on cardiovascular health. -
Heptapeptide
GRGDSPC is a thiolated heptapeptide that enhances cell adhesion by targeting integrins on cell surfaces. This peptide is commonly used in cell culture and tissue engineering applications to promote cell attachment and proliferation. Its biochemical properties make it an essential tool for studying cellular interactions and tissue regeneration. -
Osteocalcin Peptide Fragment
Osteocalcin (7-19) (human) is a peptide fragment derived from osteocalcin, primarily serving as a peptide tag in biochemical applications. This fragment retains key structural properties that facilitate its use in various research settings, including studies related to bone metabolism and mineralization. Its utility in protein labeling and modification enables researchers to investigate osteocalcin's biological roles in osteogenesis and its potential implications in metabolic regulation. -
N-formylated Peptide Substrate
For-Met-Leu-pNA is an N-formylated peptide substrate designed for use in deformylase assays. This compound serves as a valuable analytical tool to investigate the activity and kinetics of deformylases, key enzymes involved in protein maturation processes. Its specificity and utility make it ideal for studying post-translational modifications and protein degradation pathways in biochemical research.
