Muscle Homing Peptide M12 targets surface proteins on muscle cells, facilitating enhanced cellular uptake of nanoparticles within myoblasts in vitro. Its ability to bind specifically to muscle tissue makes it a valuable tool in drug delivery applications. Muscle Homing Peptide M12 can be covalently conjugated to PLGA-PEG nanoparticles through N-terminal α-amino groups using the N-hydroxysuccinimide ester reaction, thereby improving the localization and effectiveness of therapeutic agents in muscle tissues.
Muscle Homing Peptide M12 targets surface proteins on muscle cells, facilitating enhanced cellular uptake of nanoparticles within myoblasts in vitro. Its ability to bind specifically to muscle tissue makes it a valuable tool in drug delivery applications. Muscle Homing Peptide M12 can be covalently conjugated to PLGA-PEG nanoparticles through N-terminal α-amino groups using the N-hydroxysuccinimide ester reaction, thereby improving the localization and effectiveness of therapeutic agents in muscle tissues.
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