INF7

Catalog No.: A86563
Polypeptide
INF7 is a derivative of the N-terminal domain of the HA2 protein that functions primarily as a polypeptide. It disrupts the stability of endosomal membranes through a mechanism that does not rely on membrane fusion, making it effective in enhancing the endosomal escape of complex or liposome-encapsulated proteins. This property allows for improved intracellular signaling and increased retention of molecular imaging probes when co-encapsulated with INF7 in liposomes, facilitating various biological research applications.
Grouped product items
Size Price Stock Qty
1mg
$50.00
In stock
5mg
$125.00
In stock
10mg
$210.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionINF7 is a derivative of the N-terminal domain of the HA2 protein that functions primarily as a polypeptide. It disrupts the stability of endosomal membranes through a mechanism that does not rely on membrane fusion, making it effective in enhancing the endosomal escape of complex or liposome-encapsulated proteins. This property allows for improved intracellular signaling and increased retention of molecular imaging probes when co-encapsulated with INF7 in liposomes, facilitating various biological research applications.
Product Information
Catalog NumA86563
FormulaC124H169N27O37S2
Molecular Weight2693.96
CAS Number185462-59-3
SequenceGly-Leu-Phe-Glu-Ala-Ile-Glu-Gly-Phe-Ile-Glu-Asn-Gly-Trp-Glu-Gly-Met-Ile-Asp-Gly-Trp-Tyr-Gly-Cys
Sequence shorteningGLFEAIEGFIENGWEGMIDGWYGC
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