N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies.
N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies.
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