Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
3-(Piperidin-4-yl)propan-1-ol hydrochloride functions as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the target selection and degradation of specific proteins, enabling novel therapeutic approaches in targeted protein degradation research. Its application extends to the development of innovative strategies in drug discovery and cellular biology studies. -
PROTAC Linker
Hydroxy-PEG7-C2-COOH is a polyethylene glycol (PEG) based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins with E3 ligase recruiters, thereby enabling selective degradation of specific intracellular proteins. Its application is vital in the development of novel therapeutic strategies for cancer treatment and other disease models. -
PROTAC Linker
Benzyl (5-aminopentyl)carbamate hydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in merging target proteins with E3 ubiquitin ligases, thereby enabling selective degradation of specific proteins. It is utilized in various research applications, including drug discovery and protein modulation studies. -
PROTAC Linker
Benzyl hex-5-yn-1-ylcarbamate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of bifunctional molecules capable of selectively degrading target proteins through the ubiquitin-proteasome pathway. Its application in research encompasses the exploration of targeted protein degradation strategies and the investigation of protein function in cellular contexts. -
PROTAC Linker
Cbz-NH-C2-PEG3-Br is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (PROteolysis TArgeting Chimeras) synthesis. This compound facilitates targeted protein degradation by linking a ligand to an E3 ubiquitin ligase, enhancing the efficiency of PROTAC-mediated cellular mechanisms. Its application extends to the development of innovative therapeutic strategies in cell biology and drug discovery, enabling researchers to explore the modulation of complex protein interactions. -
PROTAC Linker
4-(4-Cyanobenzyl)piperidine, HCl serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound is essential in the synthesis of PROTACs for targeted protein degradation research, enabling the selective modulation of protein levels in cellular systems. Its structural features make it suitable for optimizing binding affinities in various applications within drug discovery and therapeutic research. -
PROTAC Linker
Benzyl 3-(2-bromoethyl)azetidine-1-carboxylate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of stable linkages between target proteins and E3 ligases, enhancing the specificity and efficacy of targeted degradation strategies. It is primarily used in chemical biology research to modulate protein levels and study the dynamics of cellular pathways. -
PROTAC Linker
Ac4GlcNAlk is an alkyl chain-based PROTAC linker designed for use in the synthesis of PROTAC molecules. It facilitates targeted protein degradation by linking a ligand to E3 ubiquitin ligases, enabling the selective modulation of protein levels in cells. This compound is valuable for research in pharmacology, especially in the development of therapeutic strategies aimed at protein degradation pathways. -
PROTAC Linker
NH2-PEG-C2-methanamine is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the conjugation of ligands and enhances the stability and efficacy of the resulting compounds. It is widely utilized in research applications focused on targeted protein degradation and the development of novel therapeutic interventions. -
PROTAC Linker
19-Bromononadecanoic acid serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the recruitment of E3 ligases to target proteins, thereby promoting selective degradation in cellular environments. It is instrumental in advancing research on targeted protein degradation and therapeutic applications in various diseases. -
PROTAC Linker
Potassium 6-hydroxyhexanoate is a PROTAC linker that facilitates the development of Proteolysis Targeting Chimeras (PROTACs). This compound provides a versatile connection between target proteins and E3 ligases, enabling targeted protein degradation. It is essential for the synthesis of novel PROTACs utilized in drug discovery and development for therapeutic applications. -
PROTAC Linker
[1,4′-Bipiperidine]-ethyl formate dihydrochloride functions as a PROTAC linker, facilitating the synthesis of PROTACs. This compound is integral for creating targeted protein degradation systems, enabling the selective modulation of protein levels within cells. Its chemical properties support the development of novel therapeutic strategies in cellular biology and drug discovery research. -
PROTAC Linker
Methyl 4-(piperidin-4-yloxy)benzoate hydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound is essential for synthesizing PROTACs, enabling targeted protein degradation with potential applications in therapeutic research. Its unique chemical structure enhances the specificity and efficiency of PROTAC design, making it a valuable tool in drug discovery and cellular biology studies. -
PROTAC Linker
6-((2-((Tert-butoxycarbonyl)amino)ethyl)amino)-6-oxohexanoic acid is a chemical compound designed as a PROTAC (proteolysis-targeting chimera) linker. This linker facilitates the conjugation of ligands to E3 ligases, enabling targeted protein degradation. Its applications primarily lie in drug discovery and development, particularly in the study of protein interactions and degradation pathways. Researchers utilize this compound to create innovative therapeutic strategies by harnessing the cellular ubiquitin-proteasome system. -
PROTAC Linker
Mal-NH-PEG6-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the efficient conjugation of ligands to target proteins for targeted degradation applications. Mal-NH-PEG6-CH2CH2COOPFP ester is pivotal in advancing research in targeted protein modulation and therapeutic development. -
PROTAC Linker
Z-5-Ava-OH is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of PROTACs by providing a flexible and effective linkage between target proteins and E3 ligases. Its application in research enables the selective degradation of specific proteins, advancing studies in targeted protein modulation and therapeutic intervention. -
PROTAC Linker
TBS-PEG4-O-alkyne is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of protein ligands to an E3 ubiquitin ligase, allowing for targeted degradation of specific proteins. Its key biological activity lies in enhancing the solubility and bioavailability of PROTACs, making it an essential component in targeted protein degradation research. TBS-PEG4-O-alkyne is widely utilized in pharmacological studies and drug discovery applications. -
PROTAC Linker
(R)-Boc-4-NH2-3,3-difluoropiperidin is a PROTAC linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates protein degradation by promoting targeted ubiquitination of specific proteins, enabling researchers to modulate protein levels in cellular systems. It serves as a valuable tool in the study of protein function and the development of therapeutic strategies aimed at diseases driven by dysregulated protein activity. -
PROTAC Linker
7-Bromoheptan-1-amine hydrobromide is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation by linking a ligand to an E3 ligase, enhancing the specificity and efficacy of therapeutic agents. It is valuable in the development of novel approaches for cancer therapy and other diseases through the modulation of protein levels. -
PROTAC Linker
4-(1-(tert-Butoxycarbonyl)azetidin-3-yl)benzoic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimera (PROTAC) molecules. This compound facilitates the recruitment of E3 ubiquitin ligases, enabling the selective degradation of target proteins. Its application is pivotal in drug discovery and development processes aimed at modulating protein levels within cellular pathways. -
PROTAC Linker
tert-Butyl (2-(chlorosulfonyl)ethyl)carbamate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound effectively enables the conjugation of targeting ligands to E3 ligases, thereby promoting targeted protein degradation. Its utility in chemical biology research enhances the potential for therapeutic applications through modulation of protein levels in cells. -
PROTAC Linker
3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoic acid is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in connecting targeting ligands to E3 ligase recruiters, enabling the selective degradation of specific proteins. Its application extends to drug discovery and development, particularly in the context of targeted protein degradation strategies. -
PROTAC Linker
4-Amino-cyclohexanecarboxylic acid methyl ester hydrochloride serves as a key linker in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound enhances the conjugation of target proteins to E3 ligases, facilitating the ubiquitination and subsequent degradation of specific proteins. It is essential for researchers developing targeted protein degradation strategies in various biological studies and therapeutic applications. -
PROTAC Linker
2-(4-((tert-Butoxycarbonyl)amino)cyclohexyl)acetic acid is a versatile linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). Its structure enables efficient conjugation of target proteins and E3 ligases, facilitating targeted protein degradation. This compound serves as a valuable tool in drug discovery and development, particularly in studies focusing on the modulation of cellular protein levels. -
PROTAC Linkers
N'-Boc-N-(Gly-Oleoyl)-Lys is a specialized linker designed for use in PROTAC (proteolysis-targeting chimera) assembly. This compound features an alkyl chain that enhances hydrophobic interactions, facilitating the effective targeting and degradation of specific proteins within cells. It is particularly valuable for researchers synthesizing diverse PROTACs aimed at modulating protein levels for therapeutic purposes. -
PROTAC Linker
Propargyl-(trans)-cyclohexanediamine-Boc is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the covalent connection between a protein of interest and an E3 ligase, enhancing targeted protein degradation. Its application in research supports the development of innovative therapeutic strategies in oncology and other fields by enabling selective degradation of disease-associated proteins. -
PROTAC Linker
Diethyl octanedioate functions as a PROTAC linker, instrumental in the synthesis of proteolysis-targeting chimeras (PROTACs). This chemical scaffold enhances the stability and efficacy of designed PROTACs, facilitating targeted protein degradation. Its application is significant in studying protein interactions and developing therapeutic modalities aimed at modulating cellular processes through targeted degradation. -
PROTAC Linker
Methyl 3-((tert-butoxycarbonyl)amino)propanoate serves as a PROTAC linker, facilitating the assembly of proteolysis-targeting chimeras. This compound is essential in the design and synthesis of PROTAC molecules, which harness the ubiquitin-proteasome system to selectively degrade target proteins. Its application is pivotal in advancing therapeutic strategies in cancer research and drug discovery by enabling targeted protein degradation. -
PROTAC Linker
Methyl 6-(chlorosulfonyl)hexanoate is a critical PROTAC linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). This compound facilitates the development of innovative therapeutic agents by enabling targeted protein degradation. Its structural characteristics support efficient conjugation to both ligand and E3 ligase, making it a valuable tool in drug discovery and development research. -
PROTAC Linkers
Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of warheads to E3 ligases, enhancing the efficiency of target protein degradation. Mal-NH-PEG12-CH2CH2COOPFP ester is ideal for applications in targeted protein degradation research and therapeutic development. -
PROTAC Linker
1,4-Phenylenedimethanamine dihydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for constructing bifunctional molecules that induce targeted degradation of specific proteins, enhancing the study of protein function and cellular mechanisms. Its application in chemical biology enables researchers to explore innovative therapeutic strategies by modulating protein levels within various biological systems. -
PROTAC Linker
Heptacosanedioic Acid is a PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). By linking E3 ligases to target proteins, it enhances targeted degradation pathways within cells. This compound is instrumental in research applications focusing on protein regulation and degradation, providing insights into various cellular processes and diseases. -
PROTAC Linker
6-Bromohexanoyl Chloride is a versatile PROTAC linker employed in the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the assembly of proteins for targeted degradation, thereby enhancing the study of protein regulation in various biological processes. This compound is integral for researchers developing novel therapeutic strategies aimed at modulating specific protein levels in cellular environments. -
PROTAC Linker
tert-Butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)carbamate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This reagent aids in the construction of bifunctional molecules that can selectively degrade target proteins, making it valuable in drug discovery and therapeutic research, particularly for optimizing protein degradation pathways. -
PROTAC Linker
Sebacic acid monomethyl ester is a versatile PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). This compound is essential for establishing the molecular connections necessary to selectively direct protein degradation, enhancing the study of protein function and therapeutic mechanisms. Its structural properties make it suitable for various applications in chemical biology and drug discovery processes. -
PROTAC Linker
PIP-C-3-Azaspiro[5.5]undecane-boc serves as a pivotal linker in the development of PROTAC (Proteolysis Targeting Chimera) molecules. This compound is essential for the synthesis of the PROTAC SOS1 degrader-10, contributing to targeted protein degradation studies. Its unique structural features facilitate effective protein recruitment and degradation, making it a valuable tool for researchers in exploring novel therapeutic strategies. -
PROTAC Linker
Tert-butyl (4-((tert-butoxycarbonyl)amino)phenethyl)carbamate serves as a PROTAC linker, facilitating the development of targeted protein degradation therapeutics. This compound plays a crucial role in the synthesis of PROTAC molecules by enabling the conjugation of targeting ligands to E3 ligases. Its utility in chemical biology aids researchers in exploring novel methods for protein modulation and degradation in various biological systems. -
PROTAC Linkers
Fmoc-NH-PEG15-CH2CH2COOH is a polyethylene glycol (PEG) based PROTAC linker designed for the synthesis of Proteolysis-Targeting Chimeras (PROTACs). This compound facilitates the effective conjugation of target proteins to E3 ligases, promoting the degradation of specific proteins within cells. It is suitable for applications in targeted protein degradation research and the development of novel therapeutic strategies. -
PROTAC Linker
Ethyl 3-aminopropanoate is a versatile PROTAC linker that facilitates the construction of proteolysis-targeting chimera (PROTAC) molecules. By connecting ligand-modified targets with E3 ligase recruiters, this compound enables selective ubiquitination and subsequent degradation of specific proteins. Its application in PROTAC development enhances research in targeted protein degradation and therapeutic interventions in various diseases. -
PROTAC Linker
Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of innovative therapeutic agents by promoting selective degradation of target proteins. Its utility in chemical biology research makes it valuable for studying protein turnover and the modulation of cellular pathways. -
PROTAC Linker
Ethyl 5-bromo-4-oxopentanoate serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the development of novel therapeutic strategies by enabling targeted degradation of specific proteins within cellular contexts. Its application in PROTAC assembly makes it a valuable reagent in chemical biology and drug design research. -
PROTAC Linker
19-Hydroxynonadecanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the targeting and degradation of specific proteins, thereby playing a crucial role in protein modulation studies. It is primarily utilized in the synthesis of innovative therapeutic agents designed for targeted protein degradation research. -
PROTAC Linker
Boc-PEG3-O-methyl acetate is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It facilitates the conjugation of target proteins and E3 ubiquitin ligases, enhancing the efficiency of targeted protein degradation. This versatile linker is particularly useful in chemical biology and drug discovery applications focused on targeted protein modulation. -
PROTAC Linker
Methyl 4-((tert-butoxycarbonyl)amino)butanoate is a PROTAC linker that facilitates the development of targeted protein degradation systems. This compound plays a crucial role in synthesizing PROTACs, enabling the selective degradation of specific proteins, thus providing valuable insights into protein function and regulation. Its application in chemical biology research supports advancements in therapeutic strategies aimed at diverse diseases. -
PROTAC Linker
Tert-butyl (3-cyanopropyl)(methyl)carbamate functions as a PROTAC linker, facilitating the creation of protein-targeting chimeras. This compound is essential for developing Proteolysis Targeting Chimeras (PROTACs), which are utilized in targeted protein degradation studies. Its structural properties contribute to effective interactions with protein partners, making it suitable for advancing research in targeted therapeutics and cellular modulation. -
PROTAC Linker
3-[Benzyl(methyl)amino]propanoic acid functions as a PROTAC linker, instrumental in the construction of PROTAC molecules that facilitate targeted protein degradation. This reagent enhances the therapeutic efficacy of PROTACs by enabling the selective removal of specific proteins within cellular environments. It is crucial for researchers developing novel approaches to study protein dynamics and therapeutic interventions in various disease states. -
PROTAC Linker
H2N-PEG2-CH2COOtBu hydrochloride is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates the conjugation of target proteins to E3 ligases, enabling efficient cellular degradation of specific proteins. This compound is essential for research applications focused on targeted protein degradation and the development of novel therapeutic strategies in various diseases. -
PROTAC Linker
m-PEG12-Br is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its primary mechanism involves facilitating the conjugation of ligands to E3 ubiquitin ligases, enabling targeted protein degradation. m-PEG12-Br enhances the solubility and bioavailability of PROTACs, making it a valuable tool in chemical biology and drug discovery applications. -
PROTAC Linker
2-(4-(2-Aminoethyl)piperazin-1-yl)ethan-1-ol serves as a linker in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the conjugation of target proteins for ubiquitin-mediated degradation. It is essential for synthesizing innovative PROTACs that can enhance the specificity and efficacy of targeted protein degradation therapies in various biological research applications. -
PROTAC Linkers
Hydroxy-PEG7-CH2-Boc is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the effective conjugation of target proteins and E3 ligases, enhancing the development of targeted protein degradation strategies. Its hydrophilic properties contribute to improved solubility and bioavailability, making it suitable for diverse research applications in drug discovery and pharmacological studies.
