Catalog No.
Product Name
Application
Product Information
Citations
-
PROTAC Linker
7-((Tert-butyldimethylsilyl)oxy)heptan-1-ol is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the assembly of targeted protein degradation complexes by linking ligands to E3 ligase receptors. Its application is essential in the development of novel therapeutic strategies for various diseases by enabling selective degradation of specific proteins. -
PROTAC Linker
tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate is a PROTAC linker utilized in the synthesis of PROTAC (Proteolysis-Targeting Chimeras) molecules. This compound enhances the development of targeted protein degradation systems, facilitating the selective removal of specific proteins from cells. It serves as a crucial component in research aimed at addressing various diseases by enabling the modulation of protein levels through controlled proteolysis. -
PROTAC Linker
N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a PEG-based linker designed for the development of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the assembly of PROTACs by linking the E3 ligase to target proteins, enhancing targeted protein degradation. Its stability and solubility in biological systems make it suitable for various research applications in drug discovery and cellular biology. -
PROTAC Linker
tert-Butyl (3-aminopropoxy)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound enhances the specificity and efficacy of targeted protein degradation by providing a versatile connection between the ligand and the E3 ubiquitin ligase. Its application in chemical biology enables researchers to investigate protein functions and therapeutic interventions through the modulation of cellular protein levels. -
PROTAC Linker
Benzyl 2-cyanoacetate is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in linking target proteins to E3 ligases, enhancing targeted protein degradation. Its application is essential for researchers developing innovative therapeutics in cancer and other diseases by enabling the selective modulation of protein levels within cells. -
PROTAC Linker
(S)-tert-Butyl 3-(piperazin-1-yl)pyrrolidine-1-carboxylate is a key PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins by linking ligands that recruit an E3 ligase to the target protein. Its application in PROTAC research aids in the development of novel therapeutics for various diseases by enabling precise modulation of protein levels. -
PROTAC Linker
3-(Piperidin-4-yl)propan-1-amine is a specialized PROTAC linker that facilitates the development of targeted protein degradation systems. This compound is essential for the synthesis of PROTACs, allowing researchers to create bifunctional molecules that induce degradation of specific proteins. Its structural features enhance binding affinity and stability, making it a valuable tool in drug discovery and development. -
PROTAC Linker
tert-Butyl 18-bromooctadecanoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases, enabling targeted protein degradation. Its distinct structure allows for effective conjugation with various targeting moieties, making it a valuable tool in drug discovery and development focused on modulating protein levels in cellular contexts. -
PROTAC Linker
tert-Butyl ((3-aminocyclobutyl)methyl)carbamate serves as a versatile PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound aids in the selective degradation of target proteins, thereby advancing studies in protein homeostasis and therapeutic interventions. Its application in the development of PROTACs positions it as a crucial reagent in chemical biology and drug discovery research. -
PROTAC Linker
N,N'-Di-Boc-1,4-butanediamine functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the synthesis of PROTACs, enabling targeted protein degradation for various applications in chemical biology. Its structural properties contribute to the stability and efficiency of PROTAC conjugates in research studies. -
PROTAC Linker
tert-Butyltrimethylsilane-PEG2-NH2 is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by linking E3 ubiquitin ligases to target proteins, enabling targeted protein modulation. Its application is instrumental in advancing research in targeted protein degradation and therapeutic discovery. -
PROTAC Linker
3-(Aminomethyl)cyclobutanecarboxylic acid hydrochloride acts as a PROTAC linker, facilitating the assembly of Proteolysis Targeting Chimeras (PROTACs). This compound enables the effective ubiquitination and subsequent degradation of target proteins by linking ligands to E3 ligases. Its use is critical in research focused on targeted protein degradation and therapeutic applications in various diseases, including cancer. -
PROTAC Linker
(S,R,S)-Ahpc-PEG6-azide is a click chemistry PROTAC linker that integrates an E3 ligase ligand and a PEG6 arm, facilitating the advancement of PROTAC research and discovery. The hydrophilic PEG spacer enhances solubility in aqueous environments, making it suitable for various biological applications. The presence of the azide functionality allows for efficient click chemistry reactions with alkyne, DBCO, or BCN molecules, thereby enabling versatile conjugation strategies in drug development. -
PROTAC Linker
Cyano-PEG4-cyano is a bifunctional PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a polyethylene glycol (PEG) spacer, which enhances solubility and biocompatibility. Cyano-PEG4-cyano serves as a crucial component in the development of targeted protein degradation strategies, enabling researchers to investigate cellular protein dynamics and therapeutic interventions in disease models. -
PROTAC Linker
7-Oxoheptanoic acid methyl ester serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficiency of targeted protein degradation by connecting an E3 ligase ligand to a targeting moiety. Its role in research applications includes investigating novel therapeutic strategies for diseases by promoting selective protein degradation. -
PROTAC Linker
5-((tert-Butyldimethylsilyl)oxy)pentanal is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of proteins by enabling the recruitment of E3 ligases, thus enhancing the efficacy of targeted protein degradation strategies. Its use in research applications allows for the advancement of therapeutic development in areas such as cancer and autoimmune diseases. -
PROTAC Linker
trans-3-Aminocyclobutanecarboxylic acid serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). By connecting target proteins with E3 ubiquitin ligases, it enhances the selective degradation of specific proteins. This compound is pivotal for research applications in targeted protein degradation and therapeutic development in various diseases. -
PROTAC Linker
tert-Butyl 1-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate serves as an effective PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective targeting and degradation of specific proteins, making it valuable for research in targeted protein degradation and therapeutic development. Its structure supports stable conjugation with target ligands, enhancing the efficacy of PROTAC strategies in cellular assays. -
PROTAC Linker
15-(tert-Butoxy)-15-oxopentadecanoic acid is a specialized PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enables the targeted degradation of specific proteins, enhancing the utility of PROTAC technology in drug discovery and therapeutic research. It is essential for the synthesis of effective PROTACs, allowing researchers to manipulate protein levels within cellular systems for various applications in cancer research and other diseases. -
PROTAC Linker
Benzyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate serves as a valuable PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables effective engagement and regulation of target proteins by harnessing the ubiquitin-proteasome system, making it instrumental in various biochemical studies focused on targeted protein degradation and therapeutic applications in drug discovery. -
PROTAC Linker
Boc-C-PEG2-I is a versatile linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the covalent attachment of protein ligands to E3 ubiquitin ligases, enabling targeted degradation of specific proteins within the cell. Its PEGylated structure enhances solubility and stability, making it suitable for various biochemical and cellular applications in drug discovery and molecular biology research. -
PROTAC Linker
Ethyleneglycolbis(monochloroacetate) serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its structure enables effective conjugation of target-specific ligands to E3 ligase recruiters, thereby promoting targeted protein degradation in cellular systems. This reagent is essential for researchers investigating the regulation of protein levels and the therapeutic potential of targeted protein modulation. -
PROTAC Linker
Ethyl 2-(3-chloropropoxy)acetate serves as a versatile PROTAC linker, facilitating the construction of PROTAC molecules. This compound plays a crucial role in targeted protein degradation research, enabling the development of novel therapeutic strategies by linking target proteins to E3 ubiquitin ligases. Its application is essential for advancing studies in drug discovery and cellular biology. -
PROTAC Linker
N1-Benzyl-N1-methylethane-1,2-diamine serves as a potent PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for connecting ligands to E3 ligase moieties, enabling targeted protein degradation. Its structural properties make it suitable for various research applications in drug discovery and targeted therapeutics. -
PROTAC Linker
PEG2-C-NH2 is a PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in enabling the selective degradation of target proteins through the ubiquitin-proteasome pathway. Its versatile linking capabilities make it an essential reagent for research on targeted protein degradation and its therapeutic potential in various diseases. -
PROTAC Linker
Benzyl 4-((2-aminoethoxy)methyl)piperidine-1-carboxylate is a PROTAC linker essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking target proteins to E3 ligases, enhancing selective degradation pathways. Research applications include cellular studies investigating protein dynamics and the therapeutic potential of targeted degradation in various diseases. -
PROTAC Linker
Hydroxy-PEG3-ethyl ester functions as a PROTAC (Proteolysis-targeting chimera) linker, facilitating the construction of bifunctional molecules for targeted protein degradation. This compound enhances the solubility and intracellular delivery of therapeutic agents, making it valuable for research in protein degradation pathways and targeted therapy development. Its application extends to the design of innovative PROTACs aimed at specific protein targets in cellular signaling and disease models. -
PROTAC Linker
10-(Benzyloxy)-10-oxodecanoic acid serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its unique structural properties enable the selective degradation of target proteins, making it a valuable tool for researchers in drug discovery and cellular biology. This compound is instrumental in studies focused on targeted protein degradation and therapeutic development. -
PROTAC Linker
Boc-MeN-C5-OH is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the selective degradation of target proteins by promoting their recruitment to the ubiquitin-proteasome system. Its hydrophilic nature enhances solubility and cellular uptake, making it suitable for a variety of biochemical applications in drug development and molecular biology studies. -
PROTAC Linker
tert-Butyl (4-hydroxybicyclo[2.2.2]octan-1-yl)carbamate is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the effective recruitment of E3 ubiquitin ligases to target proteins, enabling targeted protein degradation. This compound is essential for researchers focused on developing novel therapeutic strategies involving targeted protein modulation and selective degradation pathways. -
PROTAC Linker
(9H-Fluoren-9-yl)methyl (4-aminobutyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enables the conjugation of target proteins to E3 ligases, promoting selective ubiquitination and subsequent proteasomal degradation. It is valuable in drug discovery and molecular biology research for manipulating protein expression levels and studying protein function. -
PROTAC Linker
17-Methoxy-17-oxoheptadecanoic acid is a PROTAC linker that facilitates the targeted degradation of specific proteins through the ubiquitin-proteasome pathway. This compound plays a critical role in the synthesis of PROTACs, enabling the selective modulation of protein levels in cellular systems. Its application extends to research in protein biology, drug discovery, and therapeutic development aimed at various diseases. -
PROTAC Linker
Methyl 6-aminohexanoate serves as a PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the selectivity and efficacy of targeted protein degradation. Its structural properties make it an essential tool in chemical biology and drug discovery for achieving specific modulation of protein activity. -
PROTAC Linker
trans-1,4-Cyclohexanedicarboxylic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This reagent enhances the binding affinity and specificity of PROTACs, allowing for targeted protein degradation in various biological systems. Its application is crucial for researchers investigating protein dynamics and cellular regulation through targeted therapeutic strategies. -
PROTAC Linker
Octa-1,7-diyne is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables effective target degradation by linking target proteins to E3 ligases, thus promoting ubiquitination and subsequent proteasomal degradation. Its application in PROTAC research underscores its significance in the development of novel therapeutics aimed at selectively eliminating unwanted proteins. -
PROTAC Linker
tert-Butyl 20-bromoicosanoate serves as a versatile PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound is integral in constructing bifunctional molecules that can target specific proteins for degradation via the ubiquitin-proteasome pathway. Its unique structure enhances the selectivity and efficacy of PROTACs in cellular studies and therapeutic applications, making it a valuable reagent for researchers in targeted protein degradation. -
PROTAC Linker
1-Boc-4-(4-Carboxybenzyl)piperazine is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies, enabling researchers to selectively degrade specific proteins in biological research. Its unique structure enhances the binding efficiency of PROTACs, making it suitable for a wide range of applications in biochemistry and drug discovery. -
PROTAC Linker
6-tert-Butyl 2-methyl 6-azaspiro[3.4]octane-2,6-dicarboxylate is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by promoting interactions between E3 ligases and specific proteins of interest. Its unique structural attributes enhance the efficiency of PROTAC development for studies in cellular mechanisms and therapeutic targeting. -
PROTAC Linker
N1,N4-Dimethylbutane-1,4-diamine is a versatile PROTAC linker utilized in the design and synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the conjugation of target proteins to E3 ligases, thereby promoting ubiquitination and subsequent proteasomal degradation. This compound plays a crucial role in targeted protein degradation research and drug discovery applications, allowing for the selective modulation of protein levels in various biological systems. -
PROTAC Linker
tert-Butyl 4-(4-aminophenoxy)piperidine-1-carboxylate serves as a key PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). Its structure enables efficient conjugation between an E3 ligase and a target protein, enhancing the selective degradation of specific proteins within cellular environments. This compound is instrumental in drug discovery and development research aimed at targeted protein degradation strategies. -
PROTAC Linker
Thalidomide-O-PEG4-acid is a PROTAC linker designed for targeted protein degradation applications. It features a reactive site for amine-containing moieties, enabling efficient conjugation in the presence of coupling agents such as EDC or HATU. This compound is crucial for the development of bifunctional molecules that facilitate the selective degradation of target proteins, supporting research in cancer, neurodegenerative diseases, and cellular regulation. -
PROTAC Linker
Methyl 2-[3-(aminomethyl)cyclobutyl]acetate hydrochloride serves as a versatile PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins, making it valuable for targeted protein modulation in various research applications. Its structural properties contribute to the development of innovative therapeutic strategies in drug discovery and cancer research. -
PROTAC Linker
2-(2-((Tert-butyldimethylsilyl)oxy)ethoxy)acetic acid acts as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). Its structure enables efficient conjugation to target proteins, enhancing the selectivity and efficacy of targeted protein degradation strategies. This compound is valuable for researchers investigating protein regulation and the development of innovative therapeutic approaches in oncology and other fields. -
PROTAC Linker
Methyl 10-hydroxydecanoate is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the specificity and efficacy of targeted protein degradation, making it an essential reagent for researchers focused on proteomics and drug development. Its unique structural properties allow for optimal integration in various PROTAC constructs, aiding in the exploration of novel therapeutic mechanisms. -
PROTAC Linker
Benzyl 5-hydroxypentanoate is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ubiquitin ligases, enabling targeted degradation of specific proteins within cellular pathways. Its application in drug discovery research supports the development of innovative therapeutics that selectively modulate protein levels. -
PROTAC Linker
Hex-3-enedinitrile is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). Its unique chemical structure enhances the conjugation of targeting and E3 ligase components, promoting effective targeted protein degradation. This compound is instrumental in advancing research on targeted therapies and cellular protein regulation. -
PROTAC Linker
4-(Azetidin-3-yl)piperazin-2-one hydrochloride functions as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins through the ubiquitin-proteasome pathway, making it a valuable tool for studying protein function and regulation. Its application in the development of targeted protein degradation strategies supports advances in therapeutic interventions in various diseases. -
PROTAC Linker
4-Bromobutyl acetate serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting target proteins with E3 ligases, thereby promoting targeted protein degradation. It is valuable for researchers investigating the modulation of protein levels in various biological pathways. -
PROTAC Linker
5-Aminopentanoic acid hydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). By serving as a connecting unit between a target protein and an E3 ligase, it enhances the selective degradation of specific proteins within cells. This compound is valuable in chemical biology and drug discovery applications, particularly in studies focusing on targeted protein degradation mechanisms. -
PROTAC linker
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs by enabling targeted protein degradation. This compound features a bicyclononyne (BCN) group, which allows for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its applications extend to the development of advanced therapeutic modalities in chemical biology and drug discovery.
