Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
22-Bromodocosanoic acid serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the development of targeted protein degradation strategies, enabling selective gene regulation and therapeutic development. Its chemical structure supports efficient conjugation, enhancing the stability and efficacy of resulting PROTACs for various biological applications in drug discovery and molecular biology research. -
PROTAC Linker
Boc-Piperazine-piperidine-2-F-Ph-CHO is a versatile PROTAC linker that facilitates the construction of targeted protein degradation molecules. This compound enables selective ubiquitination and subsequent degradation of specific proteins, making it vital in research areas focusing on proteostasis and therapeutic development. Its utilization in synthesizing bifunctional small molecules underscores its importance in advancing drug discovery and oncology research. -
PROTAC Linker
tert-Butyl N-methyl-N-[4-(methylamino)butyl]carbamate serves as a PROTAC linker, facilitating the development of targeted protein degradation therapeutics. This compound enables the formation of PROTACs by providing a flexible and stable connection between target proteins and E3 ligases. Its structural properties make it a valuable tool for researchers investigating innovative approaches to manipulate cellular protein levels in various biological studies. -
PROTAC Linker
tert-Butyl (3-aminopropyl)carbamate hydrochloride serves as a PROTAC (Proteolysis Targeting Chimeras) linker, facilitating the design and synthesis of novel PROTAC compounds. This reagent is essential for the development of targeted protein degradation strategies, enabling researchers to modulate protein levels in a selective manner. Its application in chemical biology provides valuable insights into protein function and regulation, making it a crucial tool for drug discovery and development. -
PROTAC Linker
Cbz-NH-C4-O-NH2 is a PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases for targeted protein degradation, enhancing the efficacy of therapeutic agents. Its use in PROTAC development supports various research applications in drug discovery and development, particularly in exploring targeted degradation mechanisms in cellular models. -
PROTAC Linker
p-Phenylenedipropionic acid serves as an effective PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances target specificity and stability of PROTACs, thereby enabling selective degradation of intracellular proteins. Its application is critical in drug discovery and development, particularly in the study of protein regulation and targeted protein degradation mechanisms. -
PROTAC Linker
Tert-butyl 4-((1r,4r)-4-aminocyclohexyl)piperazine-1-carboxylate is a functional linker specifically designed for PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the assembly of bifunctional molecules that can recruit E3 ligases to target proteins for ubiquitination and degradation. It is instrumental in advancing research in targeted protein degradation and therapeutic development. -
PROTAC Linker
Boc-C-PEG3-I is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the effective conjugation of target proteins with E3 ligases, enhancing the targeted degradation of intracellular proteins. Its unique structure allows for improved solubility and stability, making it suitable for diverse research applications in drug discovery and cancer therapy. -
PROTAC Linker
tert-Butyl 4-(azetidin-3-yl)piperidine-1-carboxylate is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the assembly of bifunctional molecules that can selectively induce the degradation of target proteins, enabling targeted therapeutic interventions. Its role in PROTAC development makes it a valuable tool for researchers investigating protein regulation and degradation mechanisms in cellular processes. -
PROTAC Linker
3-Oxopropanoic acid serves as a key PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound is integral in the construction of bifunctional molecules designed to induce targeted protein degradation. Its role is essential in various research applications focused on therapeutic development and the modulation of protein activity. -
PROTAC Linker
Boc-NH-(1-Methylbicyclo[2.2.2]octane)-amino is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances binding efficiency and stability between the target protein and E3 ligase, enabling controlled degradation of specific proteins within cellular systems. It is applicable in chemical biology and drug discovery research, particularly for studies focusing on targeted protein degradation. -
PROTAC Linker
Piperazin-C-benzoic acid dihydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enhances the efficacy of PROTAC synthesis by providing a stable and versatile linker, essential for the selective modulation of protein function. Its application in chemical biology research supports the investigation of novel therapeutic strategies within drug discovery and proteomics. -
PROTAC Linker
4-Iodobutan-1-ol functions as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its structural properties promote efficient conjugation of target proteins with E3 ligases, enhancing the targeted degradation of unwanted proteins in cellular systems. This compound is valuable in research applications focused on targeted protein degradation and the development of innovative therapeutic strategies. -
PROTAC Linker
1,13-Dibromotridecane is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins through the modulation of the ubiquitin-proteasome system. It is particularly useful in the design of PROTACs for research applications in targeted protein degradation and therapeutic development. -
PROTAC Linker
Piperidine-4-carbaldehyde is a versatile PROTAC linker that plays a crucial role in enhancing protein degradation efficiency through targeted molecular interactions. Its structure allows for optimization of target protein affinity, making it an essential component in the development of novel PROTACs. This compound has demonstrated utility in the formulation of CDK2 PROTACs, facilitating advances in therapeutic strategies for targeted protein degradation. -
PROTAC Linker
BnO-PEG3-COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimera) molecules. This compound serves as a crucial component for the effective delivery of E3 ligase recruiting moieties to target proteins, facilitating their ubiquitination and subsequent degradation. BnO-PEG3-COOH is utilized in chemical biology research to investigate protein function and develop novel therapeutic strategies targeting protein misfolding and degradation pathways. -
PROTAC Linker
Octane-1,8-diamine-Glycolic acid is a versatile PROTAC linker designed for the synthesis of PROTAC molecules. Its primary application lies in cancer research, facilitating targeted protein degradation to investigate and modulate specific biological pathways. This compound plays a crucial role in the development of therapeutic strategies aimed at combating various malignancies. -
PROTAC Linker
Tert-butyl (5-aminopentyl)(methyl)carbamate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound effectively connects target proteins to E3 ligases, enabling targeted protein degradation and allowing researchers to investigate cellular processes, signaling pathways, and disease mechanisms. Its application is essential in the study of targeted therapeutics and in advancing drug discovery efforts. -
PROTAC Linker
m-PEG6-Hydrazide is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of E3 ligase ligands to target proteins by providing a flexible and hydrophilic spacer. Its unique structure enhances the solubility and stability of PROTACs, making it an essential tool for studies focused on targeted protein degradation and drug discovery applications. -
PROTAC Linker
NHBoc-PEG3-CO-OBn is a PROTAC linker featuring a polyethylene glycol (PEG) moiety that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound is designed to enhance the solubility and stability of PROTACs while enabling efficient ubiquitination of target proteins. Its application in chemical research supports the exploration of targeted protein degradation and therapeutic interventions. -
PROTAC Linker
tert-Butyl 4-(4-(ethoxycarbonyl)phenoxy)piperidine-1-carboxylate serves as a key linker in the synthesis of PROTAC molecules, facilitating targeted protein degradation. Its structural features enable the effective conjugation of degrading agents to specific target proteins, enhancing selectivity and efficacy in research applications. This compound is valuable in the development of innovative therapeutic strategies aimed at modulating protein levels within cellular environments. -
PROTAC Linker
tert-Butyl (4-(aminooxy)butyl)carbamate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in linking target proteins to E3 ubiquitin ligases, facilitating targeted protein degradation. Its application in research enhances the study of protein function and offers potential avenues for therapeutic intervention in various diseases. -
PROTAC Linker
3-(Hydroxymethyl)cyclobutanecarboxylic acid serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and selectivity of PROTACs, making it a valuable tool for targeted protein degradation studies. Its unique structural properties promote efficient binding and ease of synthesis, contributing to advancements in research applications focused on protein modulation and therapeutic interventions. -
PROTAC Linker
Ethyl 7-aminoheptanoate functions as a PROTAC linker, facilitating the development of PROTAC compounds. This molecule is utilized in the synthesis of proteolysis-targeting chimeras, which promote targeted protein degradation. Its structural properties enable efficient conjugation to various biological entities, making it valuable for research in targeted protein modulation and therapeutic applications. -
PROTAC Linker
15-Aminopentadecanoic acid acts as a PROTAC linker, facilitating the design and synthesis of PROTACs. This compound features a long alkane chain with terminal carboxylic acid and amine groups, allowing for versatile reactivity. The amino group (NH2) readily engages with carboxylic acids, activated NHS esters, and carbonyls to form stable amide bonds, making it an essential reagent for targeted protein degradation research applications. -
PROTAC Linkers
Fmoc-Gly-Gly-Gly-NH-PEG4-C2-COOH is a PEG-derived linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of targeting ligands and E3 ligase recruiters, playing a pivotal role in the development of selective protein degradation strategies. Its unique structure enhances solubility and biological compatibility, making it suitable for various applications in drug discovery and research focused on targeted protein degradation mechanisms. -
PROTAC Linker
Methyl 11-aminoundecanoate hydrochloride serves as a PROTAC (Proteolysis Targeting Chimera) linker, facilitating the development of targeted protein degradation strategies. This compound plays a critical role in the synthesis of PROTACs, which are designed to selectively induce the degradation of specific proteins within cellular systems. Its utility in chemical biology and drug discovery enhances its relevance for researchers focused on innovative therapeutic approaches. -
PROTAC Linker
Tert-butyl 4-(2-prop-2-ynoxyethyl)piperazine-1-carboxylate is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by linking them to E3 ligases, thereby modulating biological pathways. It is valuable in chemical biology and drug discovery for exploring targeted protein degradation mechanisms. -
PROTAC Linker
N-Methylpropane-1,3-diamine serves as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the design and development of targeted protein degradation strategies, enhancing the efficacy of therapeutic agents. Its utility in chemical biology makes it an essential tool for researchers exploring novel approaches in targeted therapy and drug discovery. -
PROTAC Linker
1-(2-(But-3-yn-1-yloxy)ethoxy)-6-chlorohexane serves as a versatile PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). This compound enables the selective degradation of target proteins by engaging the ubiquitin-proteasome system. Its unique chemical structure enhances the efficacy of target engagement and modulation in various biochemical applications. Researchers can utilize this linker for advancing studies in targeted protein degradation and related therapeutic strategies. -
PROTAC Linker
6-(Benzyloxycarbonylamino)caproic acid functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of these bifunctional molecules, enhancing selectivity and efficacy in targeted protein degradation studies. Applications include research in cancer therapy, drug discovery, and the investigation of protein function through regulated degradation. -
PROTAC Linker
Ph-PEG9-NH2 is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the connection between E3 ligases and target proteins, enabling targeted protein degradation. Its application is crucial in research focused on protein regulation and therapeutic development in oncology and other disease areas. -
PROTAC Linker
Methyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates the conjugation of target proteins to E3 ligases, enabling the selective degradation of unwanted proteins within cells. This compound is essential for researchers exploring novel therapeutic approaches in areas such as cancer and neurodegenerative diseases through targeted protein degradation. -
PROTAC Linker
NHBoc-PEG4-methyl acetate is a PROTAC linker designed for the synthesis of proteolysis targeting chimeras (PROTACs). Its flexible PEG4 spacer enhances solubility and bioavailability, facilitating targeted protein degradation. This compound is essential for researchers investigating novel therapeutic strategies involving targeted protein modulation through the use of PROTAC technology. -
PROTAC Linker
Ethyl 3-(piperidin-4-yl)propanoate serves as an efficient PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the ability to design and study targeted protein degradation pathways. Its application in chemical biology research supports advances in therapeutic development and targeted modulation of protein function. -
PROTAC Linker
HS-PEG6-CH2CH2-Boc is a polyethylene glycol (PEG) based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the effective conjugation of target proteins to E3 ligases, enabling selective degradation of intracellular proteins. Its utility in chemical biology makes it valuable for researchers focusing on targeted protein degradation and therapeutic interventions in various disease models. -
PROTAC Linker
(S,R,S)-AHPC-PEG4-tosyl is a PROTAC linker designed for targeted protein degradation applications. Featuring an E3 ligase ligand and a PEG4 spacer, this compound enhances solubility and hydrophilicity, facilitating improved delivery in biological systems. The tosyl group enables reactivity with amines and other nucleophiles, making it a versatile tool in drug research and discovery. -
PROTAC Linker
4-Chloro-1-butyne serves as a potent PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of PROTACs, allowing for targeted degradation of specific proteins in cellular systems. It is particularly useful in studies focused on protein interactions and modulation of cellular pathways. -
PROTAC Linker
4,4'-(Propane-1,3-diylbis(oxy))dianiline serves as an effective PROTAC linker, facilitating the development of PROTAC (proteolysis-targeting chimeras) compounds. By linking a target protein to an E3 ubiquitin ligase, this compound enhances the targeted degradation of specific proteins, making it invaluable for research in cellular regulation and therapeutic development. Its usage is pivotal in studies aimed at understanding protein homeostasis and targeted drug design. -
PROTAC Linker
Tert-Butyl 3-(3-iodopropyl)azetidine-1-carboxylate is an effective PROTAC linker designed for synthesizing Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the degradation of specific proteins by promoting the recruitment of E3 ligases, providing a powerful tool for targeted protein modulation in biological research. It is applicable in studies focused on targeted protein degradation and can aid in the exploration of therapeutic strategies in various disease contexts. -
PROTAC Linker
Methyl 8-oxooctanoate is a versatile PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). It plays a crucial role in the development of novel therapeutic agents by linking target proteins to E3 ligases, thus promoting ubiquitination and degradation. This compound is essential for researchers investigating targeted protein degradation and its implications in various diseases. -
PROTAC Linker
5-Iodopentan-1-ol is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in creating potent and selective modulators of protein function by enabling the targeted degradation of specific proteins. It is essential for researchers focused on developing innovative therapeutic strategies in the fields of drug discovery and protein engineering. -
PROTAC Linker
4-Chlorobutyronitrile is a reactive PROTAC linker utilized in the synthesis of proteolysis-targeting chimera (PROTAC) molecules. It facilitates the assembly of bifunctional small molecules designed to selectively degrade target proteins through the ubiquitin-proteasome system. This compound is valuable in the development of targeted protein degradation strategies for various therapeutic applications, including cancer research and neurological disorders. -
PROTAC Linker
Piperidin-4-amine-C5-O-C1 is a PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). It serves as a critical component in the development of bifunctional molecules designed to selectively degrade target proteins via the ubiquitin-proteasome system. This compound enables researchers to explore innovative therapeutic strategies in targeted protein degradation, advancing the field of molecular biology and drug discovery. -
PROTAC Linker
3-(Azetidin-3-yl)propan-1-ol serves as a critical PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound contributes to the selective degradation of target proteins via the ubiquitin-proteasome system. It is utilized in various research applications focused on targeted protein degradation, advancing the understanding of protein function and therapeutic intervention in diseases. -
PROTAC Linker
H2N-PEG4-Hydrazide is a PEG-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enhancing target degradation through the ubiquitin-proteasome system. H2N-PEG4-Hydrazide is essential for researchers exploring targeted protein degradation approaches in drug discovery and development. -
PROTAC Linker
3-(Methylamino)propanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structure is optimized for conjugation, enhancing the efficacy of bioconjugates in research applications focused on protein modulation and cellular control mechanisms. This compound is instrumental in advancing drug discovery efforts aimed at novel therapeutic strategies. -
PROTAC Linker
(S,R,S)-AHPC-PEG4-NHS ester is a PROTAC linker featuring an E3 ligase ligand connected by a PEG4 spacer, enhancing PROTAC drug discovery and development. Its NHS ester functionality allows for efficient coupling with amine-containing molecules, facilitating the formation of targeted protein degradation complexes. The PEG4 spacer further improves the solubility of the conjugated compounds, making this linker a valuable tool in chemical biology research and therapeutic applications. -
PROTAC Linker
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid serves as a versatile PROTAC linker, facilitating the construction of targeted protein degraders. This compound enables the formation of bifunctional molecules that can selectively recruit E3 ligases to target proteins for ubiquitination and subsequent degradation. Its application is pivotal in the development of innovative therapeutics aimed at modulating protein levels and investigating cellular pathways. -
PROTAC Linker
4,4'-(Hexane-1,6-diylbis(oxy))dibenzonitrile serves as a PROTAC linker in the assembly of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of protein ligands, enhancing selective protein degradation in targeted therapeutic applications. Its structural properties make it suitable for the development of innovative treatments in cancer and other diseases.
