Biological Activity
Quercetin inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C.
Targets
Target | Value | |
---|---|---|
Sirtuin | ||
Src | ||
PKC | ||
PI3Kγ | IC50: 2.4μM | |
PI3Kδ | IC50: 3.0μM | |
PI3Kβ | IC50: 5.4μM |
In vitro (25°C) | DMSO | 56 mg/mL (185.28 mM) | |
Water | Insoluble | ||
Ethanol | 9 mg/mL (29.77 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 5 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 33.09 mL | 165.45 mL | 330.91 mL |
0.5 mM | 6.62 mL | 33.09 mL | 66.18 mL |
1 mM | 3.31 mL | 16.55 mL | 33.09 mL |
5 mM | 0.66 mL | 3.31 mL | 6.62 mL |
*The above data is based on the productmolecular weight 302.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10766 |
---|---|
Actions | Inhibitor |
CAS No. | 117-39-5 |
Formula | C15H10O7 |
M. Wt | 302.2 |
Purity | >98% |
Synonyms | Sophoretin, Meletin, Quercetine |
SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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