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Quercetin inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C.
Targets
| Target | Value | |
|---|---|---|
| Sirtuin | ||
| Src | ||
| PKC | ||
| PI3Kγ | IC50: 2.4μM | |
| PI3Kδ | IC50: 3.0μM | |
| PI3Kβ | IC50: 5.4μM |
| In vitro | DMSO | 61 mg/mL (201.82 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 10 mg/mL (33.08 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.09 mL | 165.45 mL | 330.91 mL |
| 0.5 mM | 6.62 mL | 33.09 mL | 66.18 mL |
| 1 mM | 3.31 mL | 16.55 mL | 33.09 mL |
| 5 mM | 0.66 mL | 3.31 mL | 6.62 mL |
*The above data is based on the productmolecular weight 302.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10766 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 302.2 |
| Formula | C15H10O7 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 117-39-5 |
| Synonyms | Sophoretin, Meletin, Quercetine |
| SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
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