United States
You have no items in your shopping cart.
Publications citing Adooq Products
Z-DEVD-FMK Citations (3)
- Yosefzon Y, .et al. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size, Mol Cell, 2018, May 17;70(4):573-587.e4 PMID: 29775577
- Akashi E, .et al. Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells, Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026
- Wenquan Liang, .et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 PMID: 27905569
Chemical Information
| Catalog Num | A13503 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 668.66 |
| Formula | C30H41FN4O12 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 210344-95-9 |
| Synonyms | Caspase-3 Inhibitor |
| SMILES | O=C(N[[email protected]@H](C(C)C)C(N[[email protected]](C(CF)=O)CC(OC)=O)=O)[[email protected]](CCC(OC)=O)NC([[email protected]](CC(OC)=O)NC(OCC1=CC=CC=C1)=O)=O |
| Chemical Name | N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-valinamide, 1,2-dimethyl ester |
Description |
Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (149.55 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.96 mL | 74.78 mL | 149.55mL |
| 0.5 mM | 2.99 mL | 14.96 mL | 29.91 mL |
| 1 mM | 1.5 mL | 7.48 mL | 14.96 mL |
| 5 mM | 0.3 mL | 1.5 mL | 2.99 mL |
*The above data is based on the productmolecular weight 668.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
$63.00
VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18. ...
Special Price Starting at: $63.00
Special Price Starting at:
$100.00
Z-VEID-FMK is the specific recognition sequence for caspase-6/Mch2. ...
Special Price Starting at: $100.00
Special Price Starting at:
$120.00
Z-WEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-5 and related caspase activity. ...
Special Price Starting at: $120.00
Special Price Starting at:
$120.00
BOC-D-FMK is a Novel inhibitor of Caspase-3. ...
Special Price Starting at: $120.00
Special Price Starting at:
$220.00
Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. ...
Special Price Starting at: $220.00
Special Price Starting at:
$150.00
PETCM is an activator of caspase-3 and a stimulator of apoptosome formation in HeLa cell cytosols. ...
Special Price Starting at: $150.00
Special Price Starting at:
$36.00
Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 - 5.8 mM). Active in vivo. ...
Special Price Starting at: $36.00
Special Price Starting at:
$220.00
Z-IETD-FMK is a specific inhibitor of caspase 8. ...
Special Price Starting at: $220.00
Special Price Starting at:
$160.00
AZ 10417808, selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 uM). ...
Special Price Starting at: $160.00
Special Price Starting at:
$36.00
PAC-1 is first procaspase activating compound. ...
Special Price Starting at: $36.00
Special Price Starting at:
$100.00
Z-VDVAD-FMK is a cell-permeable, irreversible inhibitor of caspase-2. Caspase inhibitors play an important role in investigating biological processes. ...
Special Price Starting at: $100.00
Special Price Starting at:
$120.00
Caspase-3/7 Inhibitor I is a potent, cell-permeable, and specific, reversible inhibitor of caspase-3 (Ki = 60 nM) and caspase-7 (Ki = 170 nM). ...
Special Price Starting at: $120.00
Special Price Starting at:
$100.00
Ac-DEVD-CHO is an aldehyde peptide and a CPP32/Apopain Inhibitor. ...
Special Price Starting at: $100.00
Special Price Starting at:
$81.00
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM). ...
Special Price Starting at: $81.00
Special Price Starting at:
$120.00
Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, caspase-5, and caspase-9. ...
Special Price Starting at: $120.00
Special Price Starting at:
$220.00
Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. ...
Special Price Starting at: $220.00
Special Price Starting at:
$150.00
Z-YVAD-FMK is a potent cell-permeable and irreversible inhibitor of caspase-1. ...
Special Price Starting at: $150.00
Special Price Starting at:
$95.00
Ivachtin is a potent, cell-permeable, reversible, non-competitive inhibitor of Caspase-3 (IC50 = 23 nM). ...
Special Price Starting at: $95.00
Special Price Starting at:
$50.00
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC ...
Special Price Starting at: $50.00
Special Price Starting at:
$50.00
Z-DQMD-FMK is a synthetic peptide that irreversibly inhibits the activity of Caspase-3. ...
Special Price Starting at: $50.00
Special Price Starting at:
$45.00
Ac-LEHD-AFC, fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC. ...
Special Price Starting at: $45.00
Keywords:buy Z-DEVD-FMK | Z-DEVD-FMK Supplier | purchase Z-DEVD-FMK | Z-DEVD-FMK cost | Z-DEVD-FMK manufacturer | order Z-DEVD-FMK | Z-DEVD-FMK distributor | buy 210344-95-9| 210344-95-9 Supplier | purchase 210344-95-9 | 210344-95-9 cost | 210344-95-9 manufacturer | order 210344-95-9 | 210344-95-9 distributor
We Using Safe Payments:
