Catalog No.: A13503
Caspase-3 Inhibitor
Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.
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Z-DEVD-FMK 10mM * 1mL in DMSO
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Z-DEVD-FMK has been cited by 4 publications
  • Roi Ankawa, .et al. , Dev Cell, 2021, Jul 12;56(13):1900-1916 PMID: 34197726
  • Yosefzon Y, .et al. , Mol Cell, 2018, May 17;70(4):573-587.e4 PMID: 29775577
  • Akashi E, .et al. , Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026
  • Wenquan Liang, .et al. , Sci Rep, 2016, 6: 38267 PMID: 27905569
  • Biological Activity
    Discription Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.
    Target Value
    Product Information
    Catalog Num A13503
    Formula C30H41FN4O12
    Molecular Weight 668.66
    CAS Number 210344-95-9
    SMILES O=C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)[C@H](CCC(OC)=O)NC([C@H](CC(OC)=O)NC(OCC1=CC=CC=C1)=O)=O
    Synonyms Caspase-3 Inhibitor

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 98 mg/mL (146.56 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 400+5% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 14.96 mL 74.78 mL 149.55 mL
    0.5 mM 2.99 mL 14.96 mL 29.91 mL
    1 mM 1.5 mL 7.48 mL 14.96 mL
    5 mM 0.3 mL 1.5 mL 2.99 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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