Z-DEVD-FMK
Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's Z-DEVD-FMK has been cited by 6 publications
- Megumi Andoh, .et al. , Nat Commun, 2025, Jan 22;16(1):918 PMID: 39843445
- Geoffrey Canet, .et al. , Res Sq, 2024, May 14:rs.3.rs-4384494 PMID: 38798432
- Roi Ankawa, .et al. , Dev Cell, 2021, Jul 12;56(13):1900-1916 PMID: 34197726
- Yosefzon Y, .et al. , Mol Cell, 2018, May 17;70(4):573-587.e4 PMID: 29775577
- Akashi E, .et al. , Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026
- Wenquan Liang, .et al. , Sci Rep, 2016, 6: 38267 PMID: 27905569
Z-DEVD-FMK related products
Biological Activity
| Description | Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor. | ||
|---|---|---|---|
| Targets |
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Product Information
| Catalog Num | A13503 |
|---|---|
| Formula | C30H41FN4O12 |
| Molecular Weight | 668.66 |
| CAS Number | 210344-95-9 |
| SMILES | O=C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)[C@H](CCC(OC)=O)NC([C@H](CC(OC)=O)NC(OCC1=CC=CC=C1)=O)=O |
| Synonyms | Caspase-3 Inhibitor |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 98 mg/mL (146.56 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 400+5% Tween 80+ddH2O | 1 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.96 mL | 74.78 mL | 149.55 mL |
| 0.5 mM | 2.99 mL | 14.96 mL | 29.91 mL |
| 1 mM | 1.5 mL | 7.48 mL | 14.96 mL |
| 5 mM | 0.3 mL | 1.5 mL | 2.99 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
