Total item
Cart Subtotal
$0.00 - Yosefzon Y, .et al. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size, Mol Cell, 2018, May 17;70(4):573-587.e4 PMID: 29775577
- Akashi E, .et al. Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells, Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026
- Wenquan Liang, .et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 PMID: 27905569
Biological Activity
Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.
Targets
| Caspase-3 | ||||
| In vitro | DMSO | 100 mg/mL (149.55 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.96 mL | 74.78 mL | 149.55 mL |
| 0.5 mM | 2.99 mL | 14.96 mL | 29.91 mL |
| 1 mM | 1.5 mL | 7.48 mL | 14.96 mL |
| 5 mM | 0.3 mL | 1.5 mL | 2.99 mL |
*The above data is based on the productmolecular weight 668.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13503 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 668.66 |
| Formula | C30H41FN4O12 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 210344-95-9 |
| Synonyms | Caspase-3 Inhibitor |
| SMILES | O=C(N[[email protected]@H](C(C)C)C(N[[email protected]](C(CF)=O)CC(OC)=O)=O)[[email protected]](CCC(OC)=O)NC([[email protected]](CC(OC)=O)NC(OCC1=CC=CC=C1)=O)=O |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
VX-765 (Belnacasan)
VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18.
Z-VEID-FMK
Z-VEID-FMK is the specific recognition sequence for caspase-6/Mch2. Z-VEID-FMK is a synthetic peptide that irreversibly inhibits activity of…
Z-WEHD-FMK
Z-WEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-5 and related caspase activity.
Boc-D-FMK
BOC-D-FMK is a Novel inhibitor of Caspase-3.
Z-LEHD-FMK
Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.
PETCM
PETCM is an activator of caspase-3 and a stimulator of apoptosome formation in HeLa cell cytosols.
Z-VAD-FMK
Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vit…
Z-IETD-FMK
Z-IETD-FMK is a specific inhibitor of caspase 8.
Keywords:buy Z-DEVD-FMK | Z-DEVD-FMK Supplier | purchase | cost | manufacturer | order | distributor | buy 210344-95-9| 210344-95-9 Supplier | purchase 210344-95-9 | 210344-95-9 cost | 210344-95-9 manufacturer | order 210344-95-9 | 210344-95-9 distributor
Adooq Quality Guarantee
We promise all products perform as described.