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Publications citing Adooq Products
Z-DEVD-FMK Citations (3)
- Yosefzon Y,et al. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size, Mol Cell, 2018, May 17;70(4):573-587.e4 29775577
- Akashi E,et al. Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells, Oncol Rep, 2017, Jul;38(1):506-514 28586026
- Wenquan Liang,et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 27905569
Chemical Information
| Catalog Num | A13503 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 668.66 |
| Formula | C30H41FN4O12 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 210344-95-9 |
| Synonyms | Caspase-3 Inhibitor |
| SMILES code | CC(C)[[email protected]@H](C(=O)N[[email protected]@H](CC(=O)OC)C(=O)CF)NC(=O)[[email protected]](CCC(=O)OC)NC(=O)[[email protected]]( CC(=O)OC)NC(=O)OCC1=CC=CC=C1 |
| Chemical Name | L-?Valinamide, N-?[(phenylmethoxy)?carbonyl]?-?L-???-?aspartyl-?L-???-?glutamyl-?N-?[(1S)?-?3-?fluoro-?1-?(2-?methoxy-?2-?oxoethyl)?-?2-?oxopropyl]?-?, 1,?2-?dimethyl ester |
Description |
Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (149.55 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.96 mL | 74.78 mL | 149.55mL |
| 0.5 mM | 2.99 mL | 14.96 mL | 29.91 mL |
| 1 mM | 1.5 mL | 7.48 mL | 14.96 mL |
| 5 mM | 0.3 mL | 1.5 mL | 2.99 mL |
*The above data is based on the productmolecular weight 668.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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