CETP

Inhibitory Selectivity
Catalog No.Inhibitor Name CETP
A11084Anacetrapib (MK-0859)
***
A11242Torcetrapib (CP-529414)
**
A11213JTT-705 (Dalcetrapib)
*
A11397Evacetrapib (LY2484595)
****

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.



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Catalog No. Product Name Application Product Information
A11084 SALE

Anacetrapib (MK-0859)

CETP inhibitor
Anacetrapib (MK-0859) is a CETP inhibitor being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.
A11213 SALE

JTT-705 (Dalcetrapib)

CETP inhibitor
JTT-705 (Dalcetrapib) is a CETP inhibitor.Inhibition of CETP is a target to increase HDL-cholesterol and potentially reduce atherosclerosis.
A11242 SALE

Torcetrapib (CP-529414)

CETP inhibitor
Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM.
A11397

Evacetrapib (LY2484595)

CETP inhibitor
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

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