JTT-705 (Dalcetrapib)

Catalog No.: A11213

CETP inhibitor

JTT-705 (Dalcetrapib)

JTT-705 (Dalcetrapib) Chemical Structure

CAS NO. 211513-37-0

JTT-705 (Dalcetrapib) is a CETP inhibitor.Inhibition of CETP is a target to increase HDL-cholesterol and potentially reduce atherosclerosis.

Availability: In stock

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5 mg

Regular Price: $150.00

Special Price $120.00

10 mg

Regular Price: $250.00

Special Price $200.00

25 mg

Regular Price: $480.00

Special Price $384.00

50 mg

Regular Price: $780.00

Special Price $624.00

10mM * 1mL in DMSO

Regular Price: $176.00

Special Price $140.80

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Biological Activity

JTT-705 (Dalcetrapib) is a CETP inhibitor.Inhibition of CETP is a target to increase HDL-cholesterol and potentially reduce atherosclerosis.
Targets
rhCETP
0.2 μM
In vitro (25°C) DMSO 66 mg/mL (169.41 mM)
Water Insoluble
Ethanol 66 mg/mL (169.41 mM)
In vivo 0.5% methylcellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.67 mL 128.34 mL 256.67 mL
0.5 mM 5.13 mL 25.67 mL 51.33 mL
1 mM 2.57 mL 12.83 mL 25.67 mL
5 mM 0.51 mL 2.57 mL 5.13 mL

*The above data is based on the productmolecular weight 389.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11213
Actions Inhibitor
CAS No. 211513-37-0
Formula C23H35NO2S
M. Wt 389.6
Purity >98%
Synonyms JTT705
SMILES CCC(CC)CC1(CCCCC1)C(=O)NC2=CC=CC=C2SC(=O)C(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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