HIV Protease

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  1. HIV Protease inhibitor

    Atazanavir is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV).
  2. HIV Protease inhibitor

    Atazanavir is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV).
  3. HIV Protease inhibitor

    Lopinavir is an inhibitor of the HIV protease.
  4. HIV Protease inhibitor

    Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease.Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
  5. HIV Entry Inhibitor

    BMS-806, also known as BMS-378806 , is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV from entering human cells. BMS-378806 (BMS-806) is a small molecule that blocks the binding of host-cell CD4 with viral gp120 protein and therefore inhibits the first steps of HIV-1 infection.
  6. HIV Protease Inhibitor

    Saquinavir is a protease inhibitor. Proteases are enzymes that cleave protein molecules into smaller fragments. Saquinavir inhibits both HIV-1 and HIV-2 proteases.
  7. HIV-1 protease inhibitor

    Nelfinavir is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.
  8. HIV-1 inhibitor

    NBD-557 is a potentially HIV-1 inhibitor.
  9. HIV Protease Inhibitor

    Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy.
  10. HIV protease inhibitor

    Darunavir Ethanolate (Prezista) is an HIV protease inhibitor.
  11. Indinavir sulfate is a novel hydroxyaminopentane amide class of HIV-1 protease inhibitors.
  12. Amprenavir is an human immunodeficiency virus (HIV) protease inhibitor with IC50 of 14.6 ?? 12.5 ng/ml for wild-type HIV isolates
  13. HIV protease inhibitor

    Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
  14. HIV-1 Vif inhibitor

    RN-18 is a HIV-1 viral infectivity factor (HIV-1 Vif) inhibitor with an IC50 of 6 μM in nonpermissive H9 cells.
  15. HIV maturation inhibitor

    GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection.
  16. HIV-1 RT inhibitor

    Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.
  17. HIV protease inhibitor

    PNU-103017 is an HIV protease inhibitor.
  18. HIV-1 attachment inhibitor

    BMS-626529 is a potent HIV-1 attachment inhibitor. BMS-663068 is also the phosphonooxymethyl prodrug of BMS-626529 that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells.
  19. HIV-1 maturation inhibitor

  20. HIV protease inhibitor

    Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM.
  21. aspartic protease inhibitor

    Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.
  22. HIV-1 attachment inhibitor

    BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
  23. HIV-1 attachment inhibitor

    BMS-663068 tris is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
  24. HIV protease inhibitor

    Fosamprenavir Calcium Salt is a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, with improved solubility over the parent molecule and a potential for reduced pill burden on current dosing regimens; GW433908G is the calcium salt of the prodrug.
  25. HIV protease inhibitor

    Tipranavir, a nonpeptidic HIV protease inhibitor (NPPI), inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-PI-resistant HIV-1 isolates.
  26. HIV fusion inhibitor

    Enfuvirtide Acetate (T-20) is a 36 amino acid peptide corresponding to a region of gp41, the transmembrane subunit of HIV-1 envelope protein.
  27. HIV maturation inhibitor

    GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection.
  28. Allosteric IN inhibitor

    (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.
  29. HIV replication inhibitor

    ABX-464, also known as SPL-464, is an inhibitor of the HIV replication potentially for the treatment of HIV infection.
  30. HIV-1 maturation inhibitor

    GSK3532795, also known as BMS-955176, is a potent, orally active, second-generation HIV-1 maturation inhibitor. CAS: 1392312-45-6 (free base) 2023808-13-9 (HCl) 2023798-97-0 (HCl hydrate) 2097784-79-5 (oxalate)
  31. HIV capsid inhibitor

    CA inhibitor 1 (GS-6207 analog) is a potent HIV capsid inhibitor for HIV inhibition.
  32. HIV infection inhibitor

    HIV-1 inhibitor-3 is a HIV infection inhibitor extracted from patent US2018360927.
  33. HIV-1 reverse transcriptase inhibitor

    beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor.
  34. HIV protease inhibitor

    DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.
  35. HIV protease inhibitor

    Darunavir is an HIV protease inhibitor
  36. anti-HIV-1 inhibitor

    D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75.
  37. antioxidant agent

    Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. Rosamultin has inhibitory effects against HIV-1 protease. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects.

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