Ritonavir

Catalog No.: A10799

HIV Protease inhibitor

Ritonavir

Ritonavir Chemical Structure

CAS NO. 155213-67-5

Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease.Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$80.00
50 mg
$110.00
100 mg
$150.00
10mM * 1mL in DMSO
$50.00
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Biological Activity

Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease.Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Targets
CYP3A4 HIV
In vitro (25°C) DMSO 94 mg/mL (130.38 mM)
Water Insoluble
Ethanol 3 mg/mL (4.16 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.87 mL 69.36 mL 138.72 mL
0.5 mM 2.77 mL 13.87 mL 27.74 mL
1 mM 1.39 mL 6.94 mL 13.87 mL
5 mM 0.28 mL 1.39 mL 2.77 mL

*The above data is based on the productmolecular weight 720.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10799
Actions Inhibitor
CAS No. 155213-67-5
Formula C37H48N6O5S2
M. Wt 720.9
Purity >98%
Synonyms Norvir, Norvir Softgel
SMILES CC(C)C1=NC(=CS1)CN(C)C(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H](CC2=CC=CC=C2)C[[email protected]@H]([[email protected]](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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