Fosamprenavir Calcium Salt

Catalog No.: A15089

HIV protease inhibitor

Fosamprenavir Calcium Salt

Fosamprenavir Calcium Salt Chemical Structure

CAS NO. 226700-81-8

Fosamprenavir Calcium Salt is a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, with improved solubility over the parent molecule and a potential for reduced pill burden on current dosing regimens; GW433908G is the calcium salt of the prodrug.

Availability: In stock

Package Price Qty
1 mg
$90.00
5 mg
$135.00
10 mg
$225.00
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Biological Activity

Fosamprenavir Calcium Salt is a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, with improved solubility over the parent molecule and a potential for reduced pill burden on current dosing regimens; GW433908G is the calcium salt of the prodrug.
In vitro DMSO 93 mg/mL (149.12 mM)
Water Insoluble
Ethanol 3 mg/mL (4.81 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.03 mL 80.17 mL 160.34 mL
0.5 mM 3.21 mL 16.03 mL 32.07 mL
1 mM 1.6 mL 8.02 mL 16.03 mL
5 mM 0.32 mL 1.6 mL 3.21 mL

*The above data is based on the productmolecular weight 623.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15089
Actions Inhibitor
CAS No. 226700-81-8
Formula C25H34CaN3O9PS
M. Wt 623.67
Solubility DMSO
Purity >98%
Synonyms GW 433908G, Lexiva, GW433908G, GW-433908G
SMILES CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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