Catalog No.
Product Name
Application
Product Information
Citations
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Drug Metabolite
Chondroitin disaccharide Δdi-0S sodium is a drug metabolite derived from the degradation of Chondroitin sulfate. This unsaturated disaccharide can undergo derivatization with 2-aminopyridine to generate a fluorescent pyridylamino derivative, facilitating investigations into the metabolic pathway of Chondroitin sulfate. It is particularly useful for studying related disease mechanisms and elucidating the role of chondroitin in biologic systems. -
Drug Metabolite
2-Deoxokanshone L is a drug metabolite derived from the degradation of Nardosinone. It serves as a valuable marker in pharmacokinetic studies, aiding in the understanding of drug metabolism and disposition. This compound is essential for researchers investigating the metabolic pathways and therapeutic implications of Nardosinone and related compounds. -
Drug Metabolite Control
S-Methyl-D-penicillamine is a metabolite of the chelating agent Penicillamine, primarily involved in drug metabolite control. This compound exhibits significant biological activity in metal ion chelation, contributing to the detoxification and clearance of heavy metals from biological systems. It is employed in research applications focused on understanding metal metabolism and the biochemical pathways of chelation therapy. -
Drug Metabolite Control
7-APB hydrochloride is a benzofuran compound and a known metabolite of 7-MAPB. It serves as a valuable tool in drug metabolite control studies, enabling researchers to investigate the pharmacokinetics and metabolic pathways of related substances. Its application in toxicology and pharmacology research enhances the understanding of drug interactions and safety profiles in various biological contexts. -
Drug Metabolite
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SF-cysteine) serves as a drug metabolite derived from Sulforaphane. This compound has demonstrated the ability to enhance the survival rate of Nalm-6 cells in cellular studies. Its potential applications in research may include investigations into cellular response mechanisms and protective effects of dietary phytochemicals. SF-cysteine represents a valuable tool for exploring the biochemical pathways associated with cancer and other diseases. -
Drug Metabolite
4,5-Desisopropylidene topiramate is a significant metabolite of Topiramate, primarily serving as a drug metabolite. This compound is important for studying the pharmacokinetics and pharmacodynamics of Topiramate, which is utilized in the treatment of epilepsy and migraine disorders. Researchers can leverage its unique properties to explore metabolic pathways and the drug's efficacy in various clinical contexts. -
Drug Metabolite
7-Hydroxy etodolac is a metabolite of etodolac, a non-steroidal anti-inflammatory drug that functions as a cyclooxygenase (COX) inhibitor. This compound is of interest in pharmacokinetic studies and metabolism research, providing insights into the metabolic pathways of NSAIDs. Its investigation can enhance the understanding of drug efficacy and safety profiles in therapeutic applications. -
Drug Metabolite
15-Hydroxy Lubiprostone is an active metabolite of the laxative drug Lubiprostone, primarily targeting chloride channels. This compound exhibits biological activity by promoting fluid secretion in the intestinal lumen, thereby facilitating bowel movements. It is mainly utilized in research applications focused on gastrointestinal pharmacology and the mechanisms of action related to chloride channel activation. -
Drug Metabolite
3-Hydroxy desalkylgidazepam is the active metabolite of Gidazepam, playing a crucial role in the pharmacokinetics of this compound. This metabolite exhibits biological activity relevant to the study of benzodiazepine metabolism and its effects on the central nervous system. Research applications include investigations into drug interactions, toxicology studies, and the assessment of pharmacological profiles of related compounds. -
Drug Metabolite
3-(Methylphosphinico)propionic acid is a known metabolite of the herbicide glufosinate ammonium, with implications for environmental monitoring and toxicology studies. This compound's biological activity can provide insights into the degradation pathways of glufosinate and its potential effects on ecosystems. Researchers utilize this metabolite to assess the presence and impact of herbicide residues in agricultural environments. -
Drug Metabolite
Raloxifene Bismethyl Ether is a drug metabolite derived from Raloxifene, characterized by the absence of both hydroxyl groups, rendering it inactive at estrogen receptors. This compound serves as a useful tool in pharmacokinetic studies to explore metabolic pathways and the biological effects of Raloxifene and its derivatives. Its stability and metabolic profile can aid in understanding its role in therapeutic applications and safety evaluations. -
Drug Metabolite Control
AB-CHMINACA metabolite M5A is a liver-derived metabolite of the synthetic cannabinoid AB-CHMINACA. It serves as a crucial component for drug metabolite control studies, offering insights into the pharmacokinetics of AB-CHMINACA and its effects on human health. This metabolite is valuable for toxicological research and forensic analysis related to synthetic cannabinoids. -
Drug Metabolite Control
(±)13,14-EDT is an oxylipin and a metabolite of adrenic acid, produced through the cytochrome P450 (CYP) metabolic pathway. This compound serves as a valuable control in drug metabolism studies, aiding in the understanding of the biotransformation processes of various pharmaceuticals. Its biological activity is crucial for elucidating the effects of drug metabolites on physiological responses, making it an important reagent for researchers investigating drug metabolism and toxicity. -
Drug Metabolite Control
2-Amino-2'-chloro-5-nitrobenzophenone is a compound known for its role as a precursor in the synthesis of benzodiazepines. This reagent also serves as a hydrolysis product of Clonazepam, making it relevant for studies focused on drug metabolite control. Its biological activity is essential for research applications in pharmacology and toxicology, particularly in examining drug metabolism and the effects of benzodiazepine derivatives. -
Drug Metabolite
13(S)-HODE-biotin is a biotinylated derivative of 13(S)-hydroxyoctadecadienoic acid, a lipoxygenase metabolite of linoleic acid. It plays a critical role in regulating cellular responses, including modulation of platelet-activating factor and leukotriene B4, as well as calcium influx in human polymorphonuclear leukocytes. This compound is valuable for research applications involving lipid signaling pathways and inflammation studies. -
Drug Metabolite
Captopril EP Impurity J is a drug metabolite associated with the antihypertensive agent Captopril, a thiol-containing competitive angiotensin-converting enzyme (ACE) inhibitor. With an IC50 of 0.025 μM, it plays a crucial role in the modulation of blood pressure by inhibiting the conversion of angiotensin I to angiotensin II. This impurity is significant for research applications focused on drug metabolism and pharmacokinetics, enabling the study of the metabolic pathways and potential effects of Captopril. -
Drug Metabolite
Netupitant N-oxide is the primary metabolite of Netupitant, a highly selective antagonist of the neurokinin-1 (NK1) receptor. This compound is crucial for studying the pharmacokinetics and pharmacodynamics of Netupitant, contributing to the understanding of its efficacy and safety profile in clinical settings. It is particularly useful in research focusing on antiemetic therapies and the modulation of pain and anxiety pathways. -
Drug Metabolite
Dihydroechinofuran is a benzoquinone metabolite with significant relevance in drug metabolism studies. It serves as a useful tool for understanding biotransformation processes and the pharmacokinetics of various therapeutic agents. Research applications include the investigation of metabolic pathways and the assessment of drug interactions. -
Drug Metabolite
(S)-Menthiafolic acid is a naturally occurring drug metabolite derived from grape sources. It plays a significant role in the aroma profile of wines, produced during the alcoholic and malolactic fermentation processes from its glucose ester precursor. This compound is of interest in research related to wine chemistry and the modulation of sensory properties in fermented products. -
Drug Metabolite
CNJ-294 is a drug metabolite and an intermediate in the synthesis of Capmatinib. It plays a crucial role in understanding the metabolic pathways and pharmacokinetics of Capmatinib. Research applications of CNJ-294 include studies on drug metabolism, efficacy, and safety in the context of specific cancer therapies. -
Drug Metabolite
(Rac)-Mono(3,5,5-trimethylhexyl) phthalate is an important drug metabolite associated with phthalate plasticizers. This compound exhibits immunosuppressive effects, making it relevant for studies investigating the pharmacokinetics and toxicology of environmental pollutants. Its characterization aids in understanding the biological impact of plasticizers on human health and ecology. -
Drug Metabolite
7-Hydroxycannabidiol (7-OH-CBD) is a primary metabolite of cannabidiol, primarily functioning as a biomarker in drug metabolism studies. It is found in human serum and saliva, making it significant for pharmacokinetic research and therapeutic monitoring of cannabidiol-based treatments. This compound is essential for understanding the metabolic pathways of cannabinoids and their physiological effects. -
Drug Metabolite
3-Hydroxy-4-methyl-2(5H)-thiophenone is a key drug metabolite and a major acidic degradation product of Cephalexin. This compound plays a crucial role in pharmacokinetic studies and is essential for investigating the metabolic pathways of cephalosporin antibiotics. Its characterization can enhance the understanding of drug stability and efficacy in therapeutic applications. -
Drug Metabolite
Ethyl mycophenolate is a drug metabolite related to the prodrug mycophenolate mofetil, which primarily targets the immune system. It is often detected as a potential impurity in commercial formulations of mycophenolic acid, a compound widely used for immunosuppression in transplant patients. This metabolite is critical for studies examining drug efficacy, safety, and pharmacokinetics in clinical and research settings. -
Drug Metabolite
15-Keto latanoprost acid is a metabolite of latanoprost that demonstrates modest biological activity. This compound has been shown to induce a small reduction in intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. Additionally, 15-keto latanoprost exhibits miotic effects in cat eyes, causing an 8 mm Hg decrease in pupillary diameter at a concentration of 5 μg/eye. Its applications may be relevant for research involving ocular pharmacology and the mechanisms of prostaglandin action. -
Drug Metabolite
4-Hydroxytryptophol is a drug metabolite primarily involved in the metabolism of psilocin. This compound is identified in human liver microsomes and recombinant monoamine oxidase A systems, serving as an important tool for studying the pharmacokinetics and metabolic pathways of tryptamines. Although 4-hydroxytryptophol is not present in in vivo samples from mice or humans, its characterization in vitro provides valuable insights for research applications in drug metabolism and psychiatry. -
Drug Metabolite Control
Hydroxymethyl tolperisone hydrochloride is a metabolite of tolperisone, primarily formed by the cytochrome P450 isoform CYP2D6, with minor contributions from CYP2C19 and CYP1A2. This compound serves as an important analytical standard for drug metabolite control in pharmacokinetic studies. It plays a crucial role in evaluating metabolic pathways and potential drug interactions during research applications. -
Drug Metabolite Control
2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one hydrochloride is a metabolite of the anorectic agent Mazindol, functioning as a drug metabolite control. This compound is essential for studying the pharmacokinetics and metabolic pathways of Mazindol, aiding in understanding its pharmacological effects and safety profile. It is useful in research applications related to drug metabolism and therapeutic monitoring. -
Drug Metabolite
o-Desmethyl ranolazine is a drug metabolite formed through the metabolic conversion of Ranolazine by cytochrome P450 (CYP) 3A enzymes. This compound serves as an important reference in pharmacokinetic studies and can be utilized in research investigating the metabolism of therapeutic agents, particularly in the context of cardiovascular disease. Its biological activity and metabolic pathways are valuable for understanding drug efficacy and safety profiles. -
Drug Metabolite
Reduced Haloperidol, a primary metabolite of Haloperidol, functions as a dopamine receptor antagonist. It exhibits significant antipsychotic activity, primarily utilized in research related to schizophrenia and other psychotic disorders. This compound is instrumental in studies investigating the modulation of neurotransmitter systems, aiding in the reduction of hallucinations and delusions associated with these conditions. -
Drug Metabolite
Ketopynalin is a drug metabolite derived from Vatalanib. It plays a crucial role in the metabolism and pharmacokinetics of Vatalanib, making it significant for studies focused on the drug's efficacy and safety. Researchers can utilize Ketopynalin to investigate the metabolic pathways and biological effects associated with Vatalanib in various cellular and animal models. -
Drug Metabolite
(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz, functioning primarily as a non-nucleoside inhibitor of HIV-1 reverse transcriptase. This compound exhibits significant biological activity in the context of HIV research, contributing to the understanding of drug metabolism and efficacy. It is relevant for studies focusing on the pharmacokinetics and potential resistance mechanisms associated with antiretroviral therapy. -
Drug Metabolite
1-(Hydroxymethyl)-5,5-dimethylhydantoin is a drug metabolite derived from the degradation of 1,3-dimethylol-5,5-dimethylhydantoin, a compound known for its formaldehyde-releasing and antimicrobial properties. This reagent serves as a valuable reference standard in pharmacokinetic studies and investigations into metabolite behavior. Its applications extend to toxicological research, where understanding its effects and interactions can contribute to safety assessments of formaldehyde-releasing agents in various formulations. -
Drug Metabolite
1,2-Diacetylbenzene is a γ-diketone metabolite that serves as an important model for studying the reactivity of aromatic hydrocarbons with proteins. Primarily derived from the neurotoxic solvent 1,2-diethylbenzene, this compound exhibits significant biological activity and is utilized in research investigating metabolic pathways, protein interactions, and toxicological impacts. Its reactive properties make it a valuable asset in the examination of related biochemical processes. -
Drug Metabolite Control
AB-PINACA 3-Carboxyindazole metabolite is a key metabolite of the synthetic cannabinoid APINAC. This compound plays a significant role in drug metabolite control, aiding in the investigation of the metabolic pathways of synthetic cannabinoids. Its analytical applications are particularly useful in toxicology and forensic science, providing essential insights into substance use and metabolism. -
Drug Metabolite
Dibutyl 3-hydroxybutyl phosphate is a significant metabolite of tris(n-butyl) phosphate (TNBP), which is widely utilized as an alkyl organophosphate ester. This compound serves as an important reference in studies of TNBP metabolism and its biological effects. Research applications include investigations into metabolic pathways and the toxicity of organophosphate esters in biological systems. -
Drug Metabolite
Fipronil sulfide is a toxic and persistent metabolite of the insecticide Fipronil, which acts primarily on the insect central nervous system by inhibiting gamma-aminobutyric acid (GABA) receptors. This compound exhibits significant biological activity in studies related to environmental toxicity and the degradation pathways of pesticides. Research applications include assessing the impact of fipronil metabolites on non-target organisms and evaluating their long-term environmental effects. -
Drug Metabolite Control
9(E)-Erythromycin A oxime is a metabolite of Roxithromycin, a semi-synthetic macrolide antibiotic. This compound serves as a valuable control in drug metabolism studies, facilitating the investigation of metabolic pathways and pharmacokinetics. Its utilization in research contributes to understanding antibiotic metabolism and potential interactions within biological systems. -
Drug Metabolite
DL-Sulforaphane glutathione (DL-SFN-GSH) is a conjugate of Sulforaphane, acting primarily as a drug metabolite. It plays a crucial role in cellular detoxification and antioxidant defense mechanisms. DL-SFN-GSH is often utilized in research related to sulforaphane metabolism, oxidative stress, and the investigation of its protective effects against various diseases. -
Drug Metabolite Control
4-Hydroxypentanoate sodium is an active metabolite of gamma-Valerolactone, functioning primarily as a sedative. Its primary mechanism involves modulation of GABA receptors, leading to enhanced inhibitory neurotransmission. This compound is utilized in pharmacological research to study drug metabolism and to evaluate sedative effects in various experimental models. -
Drug Metabolite
Fenretinide glucuronide, a drug metabolite, is produced via the glucuronidation of Fenretinide. This conversion increases the water solubility of Fenretinide, promoting its excretion. Fenretinide glucuronide is of significant interest for research applications in cancer studies, offering insights into the pharmacokinetics and biological effects of Fenretinide in cancer treatment. -
Drug Metabolite
5-O-Desmethyl omeprazole is a metabolic product of the proton pump inhibitor Omeprazole, generated through the action of cytochrome P450 enzymes. This compound is crucial for studying drug metabolism and pharmacokinetics, particularly in understanding the biotransformation of Omeprazole. Its analysis can provide insight into drug interactions and the therapeutic efficacy of proton pump inhibitors in clinical research. -
Drug Metabolite
DDOH, a metabolite of DTT, primarily functions as a conjugating agent by forming derivatives with palmitic acid. This compound is significant for studies in metabolic processes and the examination of drug metabolism. Its ability to form conjugates makes it valuable for research involving lipid metabolism and the pharmacokinetics of drug conjugation. -
Drug metabolite
3α,5α-Tetrahydronorethisterone is a significant urinary metabolite of the synthetic progestin, Norethisterone. It plays a crucial role in pharmacokinetic studies, particularly in the assessment of progestin metabolism and elimination in clinical and research settings. Its identification and quantification can provide valuable insights into hormonal pathways and drug efficacy. -
Drug Metabolite Control
7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one is a primary metabolite of Flubromazepam, acting on the central nervous system through modulation of GABA receptors. This compound exhibits potential anxiolytic and sedative properties, making it relevant for studies on drug metabolism and pharmacokinetics. Its application is beneficial in research focused on benzodiazepine derivatives and their metabolic pathways. -
Drug Metabolite
Para-Naphthol Duloxetine is a drug metabolite derived from Duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI). This compound is important for understanding the pharmacokinetics and pharmacodynamics of Duloxetine, as it may contribute to the drug's efficacy and side effect profile. Research applications include studies on metabolic pathways, drug interactions, and the therapeutic effects of SNRIs in various clinical contexts. -
Drug Metabolite Control
Nicorandil pyridine oxide is a metabolite of Nicorandil, which acts as an activator of the sulfonylurea receptor 2B (SUR2B) and the ATP-sensitive potassium channel Kir6.2. This compound serves as a crucial tool for drug metabolite control, offering insights into the pharmacokinetics and therapeutic mechanisms of Nicorandil. Its biological activity is important for researchers studying cardiovascular effects and the modulation of ion channels in various biological systems. -
Drug Metabolite
Diphenhydramine N-oxide is a metabolite of Diphenhydramine, a first-generation H1 receptor antagonist known for its anticholinergic properties. This reagent serves as an important tool for studying the pharmacokinetics and metabolic pathways of Diphenhydramine, particularly in relation to its central nervous system effects. Researchers can utilize Diphenhydramine N-oxide to investigate its role in drug metabolism and potential therapeutic implications in various biological systems. -
Drug Metabolite
2,3,4,5-Tetrachlorophenol is a drug metabolite derived from the insecticide γ-Lindane. This compound is utilized in research to study metabolic pathways and environmental persistence of chlorinated phenolic compounds. Its biological activity provides insights into the toxicity and ecological impact of pesticide degradation products, making it valuable for toxicological and environmental studies. -
Drug Metabolite
5-Hydroxy flunixin, the primary metabolite of Flunixin, acts as a potent anti-inflammatory agent by retaining the pharmacological properties of its parent compound. This metabolite significantly contributes to pain relief and inflammation reduction in veterinary medicine, addressing conditions such as equine colic, musculoskeletal disorders, and infectious diseases in cattle. Additionally, it supports the management of mastitis-metritis-agalactia syndrome in sows, making it valuable for various therapeutic applications in animal health.
