(Rac)-8-Hydroxy-efavirenz

Catalog No.: A70900
Drug Metabolite
(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz, functioning primarily as a non-nucleoside inhibitor of HIV-1 reverse transcriptase. This compound exhibits significant biological activity in the context of HIV research, contributing to the understanding of drug metabolism and efficacy. It is relevant for studies focusing on the pharmacokinetics and potential resistance mechanisms associated with antiretroviral therapy.
Grouped product items
Size Price Stock Qty
1mg
$425.00
In stock
5mg
$1,875.00
In stock
10mg
$3,345.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz, functioning primarily as a non-nucleoside inhibitor of HIV-1 reverse transcriptase. This compound exhibits significant biological activity in the context of HIV research, contributing to the understanding of drug metabolism and efficacy. It is relevant for studies focusing on the pharmacokinetics and potential resistance mechanisms associated with antiretroviral therapy.
Product Information
Catalog NumA70900
FormulaC14H9ClF3NO3
Molecular Weight331.67
CAS Number205754-32-1
SMILESO=C1NC2=C(O)C=C(Cl)C=C2C(C(F)(F)F)(C#CC3CC3)O1
Useful Calculator

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