15-Keto latanoprost acid is a metabolite of latanoprost that demonstrates modest biological activity. This compound has been shown to induce a small reduction in intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. Additionally, 15-keto latanoprost exhibits miotic effects in cat eyes, causing an 8 mm Hg decrease in pupillary diameter at a concentration of 5 μg/eye. Its applications may be relevant for research involving ocular pharmacology and the mechanisms of prostaglandin action.
15-Keto latanoprost acid is a metabolite of latanoprost that demonstrates modest biological activity. This compound has been shown to induce a small reduction in intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. Additionally, 15-keto latanoprost exhibits miotic effects in cat eyes, causing an 8 mm Hg decrease in pupillary diameter at a concentration of 5 μg/eye. Its applications may be relevant for research involving ocular pharmacology and the mechanisms of prostaglandin action.
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