13(S)-HODE-biotin

Catalog No.: A70838
Drug Metabolite
13(S)-HODE-biotin is a biotinylated derivative of 13(S)-hydroxyoctadecadienoic acid, a lipoxygenase metabolite of linoleic acid. It plays a critical role in regulating cellular responses, including modulation of platelet-activating factor and leukotriene B4, as well as calcium influx in human polymorphonuclear leukocytes. This compound is valuable for research applications involving lipid signaling pathways and inflammation studies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description13(S)-HODE-biotin is a biotinylated derivative of 13(S)-hydroxyoctadecadienoic acid, a lipoxygenase metabolite of linoleic acid. It plays a critical role in regulating cellular responses, including modulation of platelet-activating factor and leukotriene B4, as well as calcium influx in human polymorphonuclear leukocytes. This compound is valuable for research applications involving lipid signaling pathways and inflammation studies.
Product Information
Catalog NumA70838
FormulaC28H48N4O4S
Molecular Weight536.77
CAS Number1217458-58-6
SMILESCCCCC[C@H](O)/C=C/C=C\CCCCCCCC(NNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O
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